Research Topics
| Paul S ChanSummaryAffiliation: University of Michigan Country: USA Publications
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Detail Information
Publications
Mortality reduction by implantable cardioverter-defibrillators in high-risk patients with heart failure, ischemic heart disease, and new-onset ventricular arrhythmia: an effectiveness studyPaul S Chan
Division of Cardiology, University of Michigan School of Medicine, USA
J Am Coll Cardiol 45:1474-81. 2005..To investigate the generalizability of the reduction in mortality posed by implantable cardioverter-defibrillators, we examined the effectiveness of defibrillators as applied in routine medical practice...
Incremental benefit and cost-effectiveness of high-dose statin therapy in high-risk patients with coronary artery diseasePaul S Chan
University of Michigan Department of Internal Medicine, Ann Arbor, MI, USA
Circulation 115:2398-409. 2007..However, the actual benefit and cost-effectiveness of high-dose statin therapy are unknown...
Prognostic implication of redefining indeterminate microvolt T-wave alternans studies as abnormal or normalPaul S Chan
Division of Cardiology, University of Michigan, Ann Arbor, MI, USA
Am Heart J 153:523-9. 2007..The objective of this study was to assess if patients have differences in survival prognosis based on the reasons for an indeterminate MTWA result...
Effectiveness of implantable cardioverter-defibrillators in patients with ischemic heart disease and left ventricular dysfunctionPaul S Chan
Division of Cardiology, University of Michigan, Ann Arbor, USA
Arch Intern Med 166:2228-33. 2006..To investigate the generalizabilty of this mortality reduction, we examined the effectiveness of ICDs in clinical practice...
Cost-effectiveness of a microvolt T-wave alternans screening strategy for implantable cardioverter-defibrillator placement in the MADIT-II-eligible populationPaul S Chan
VA Center for Practice Management and Outcomes Research, Ann Arbor, Michigan, USA
J Am Coll Cardiol 48:112-21. 2006....
Cost-effectiveness of radiofrequency catheter ablation for atrial fibrillationPaul S Chan
Division of Cardiology, University of Michigan School of Medicine, Ann Arbor, Michigan, USA
J Am Coll Cardiol 47:2513-20. 2006..We sought to compare the cost-effectiveness of left atrial catheter ablation (LACA), amiodarone, and rate control therapy in the management of atrial fibrillation (AF)...
Duration of resuscitation efforts and survival after in-hospital cardiac arrest: an observational studyZachary D Goldberger
Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI 48109 5869, USA
Lancet 380:1473-81. 2012....
Delayed time to defibrillation after intraoperative and periprocedural cardiac arrestJill M Mhyre
Department of Anesthesiology, The University of Michigan Health System, Ann Arbor, Michigan, USA
Anesthesiology 113:782-93. 2010..Delay in defibrillation (more than 2 min) is associated with worse survival in patients with a cardiac arrest because of ventricular fibrillation or pulseless ventricular tachycardia in intensive care units and inpatient wards...
Factors associated with neurologically intact survival for patients with acute heart failure and in-hospital cardiac arrestPhillip D Levy
Department of Emergency Medicine and the Cardiovascular Research Institute, Wayne State University School of Medicine, Detroit, Michigan, USA
Circ Heart Fail 2:572-81. 2009..The ability to predict who may survive such an event with or without neurological deficit would enhance the information on which patients and providers establish resuscitative preferences...
Health literacy and outcomes among patients with heart failurePamela N Peterson
Division of Cardiology, Denver Health Medical Center, Mail Code 0960, 777 Bannock St, Denver, CO 80204, USA
JAMA 305:1695-701. 2011..Little is known about the effects of low health literacy among patients with heart failure, a condition that requires self-management and frequent interactions with the health care system...
Meta-analysis of randomized trials of drug-eluting stents versus bare metal stents in patients with diabetes mellitusThomas F Boyden
University Michigan Medical School, Ann Arbor VA Medical Center, Ann Arbor, Michigan, USA
Am J Cardiol 99:1399-402. 2007..001). DES use is associated with a marked decrease in in-stent restenosis and target lesion revascularization in patients with diabetes. In conclusion, the analysis supports the current widespread use of DESs in these high-risk patients...
Body mass index and survival after in-hospital cardiac arrestRenuka Jain
Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, USA
Circ Cardiovasc Qual Outcomes 3:490-7. 2010..The quality and effectiveness of resuscitation processes may be influenced by the patient's body mass index (BMI); however, the relationship between BMI and survival after in-hospital cardiac arrest has not been previously studied...
Are changes in carotid intima-media thickness related to risk of nonfatal myocardial infarction? A critical review and meta-regression analysisZachary D Goldberger
Department of Internal Medicine, Division of Cardiology, University of Michigan Health System, Ann Arbor, MI, USA
Am Heart J 160:701-14. 2010..However, it remains unclear whether changes in CIMT that result from these therapies correlate with nonfatal myocardial infarction (MI)...
Vasodilator therapy in patients with aortic insufficiency: a systematic reviewAli Mahajerin
Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI 48109 0366, USA
Am Heart J 153:454-61. 2007..The use of vasodilators to improve long-term outcomes in asymptomatic patients with chronic aortic insufficiency (AI) is controversial...
Hospital-wide code rates and mortality before and after implementation of a rapid response teamPaul S Chan
Division of Cardiology, Mid America Heart Institute and University of Missouri, Kansas City, MO 64111, USA
JAMA 300:2506-13. 2008..Because a primary action of rapid response teams is to transfer patients to the ICU, their ability to reduce hospital-wide code rates and mortality remains unknown...
Delayed time to defibrillation after in-hospital cardiac arrestPaul S Chan
Saint Luke s Mid America Heart Institute, Kansas City, MO 64111, USA
N Engl J Med 358:9-17. 2008..However, empirical data on the prevalence of delayed defibrillation in the United States and its effect on survival are limited...
Usefulness of microvolt T-wave alternans to predict outcomes in patients with ischemic cardiomyopathy beyond one yearPaul S Chan
Mid America Heart Institute and University of Missouri, Kansas City, Missouri, USA
Am J Cardiol 102:280-4. 2008..Although these findings need further validation, they suggest that rescreening with MTWA may not need to be performed more frequently than once every 2 years...
Usefulness of microvolt T-wave alternans on predicting outcome in patients with ischemic cardiomyopathy with and without defibrillatorsTheodore Chow
The Lindner Clinical Trial Center, Christ Hospital and Ohio Heart and Vascular Center, Cincinnati, Ohio, USA
Am J Cardiol 100:598-604. 2007..19, ICD p = 0.73). In conclusion, MTWA, but not QRS duration, predicted mortality outcomes in patients with ischemic cardiomyopathy. Moreover, the prognostic utility of MTWA did not appear to differ by QRS duration...
Microvolt T-wave alternans: where do we go from here?Paul S Chan
J Am Coll Cardiol 47:1736; author reply 1736-7. 2006
Prognostic utility of microvolt T-wave alternans in risk stratification of patients with ischemic cardiomyopathyTheodore Chow
The Lindner Clinical Trial Center at the Christ Hospital and the Ohio Heart and Vascular Center, Cincinnati, Ohio, USA
J Am Coll Cardiol 47:1820-7. 2006..08 [1.18 to 3.66]; p = 0.01). CONCLUSIONS: Microvolt T-wave alternans is a strong and independent predictor of all-cause and arrhythmic mortality in patients with ischemic cardiomyopathy...
Keeping apples and oranges separate: reassessing clinical trials that use composite end points as their primary outcomePaul S Chan
J Am Coll Cardiol 48:850; author reply 851-2. 2006
Microvolt T-wave alternans identifies patients with ischemic cardiomyopathy who benefit from implantable cardioverter-defibrillator therapyTheodore Chow
The Lindner Clinical Trial Center at the Christ Hospital and the Ohio Heart and Vascular Center, Cincinnati, Ohio, USA
J Am Coll Cardiol 49:50-8. 2007....
High-dose statins and the IDEAL studyPaul S Chan
JAMA 295:2477; author reply 2478-9. 2006
