Jk Chan

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi Influence of the gynecologic oncologist on the survival of ovarian cancer patients
    John K Chan
    Division of Gynecologic Oncology, Department of Obstetrics, University of California, San Francisco School of Medicine, San Francisco Comprehensive Cancer Center, San Francisco, California 94143 1702, USA
    Obstet Gynecol 109:1342-50. 2007
  2. ncbi Prognostic factors for high-risk early-stage epithelial ovarian cancer: a Gynecologic Oncology Group study
    John K Chan
    Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco School of Medicine, UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, California 94143 1702, USA
    Cancer 112:2202-10. 2008
  3. ncbi Analysis of phase II studies on targeted agents and subsequent phase III trials: what are the predictors for success?
    John K Chan
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of California, San Francisco, UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA 94143 1702, USA
    J Clin Oncol 26:1511-8. 2008
  4. ncbi Prognostic factors and risk of extrauterine metastases in 3867 women with grade 1 endometrioid corpus cancer
    John K Chan
    Division of Gynecologic Oncology, Department of Obstetrics, Gynecology, and Reproductive Services, University of California, San Francisco School of Medicine, Helen Diller Family Comprehensive Cancer Center, 94143 1702, USA
    Am J Obstet Gynecol 198:216.e1-5. 2008
  5. ncbi Influence of gynecologic oncologists on the survival of patients with endometrial cancer
    John K Chan
    University of California, San Francisco UCSF School of Medicine, UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA 94143 1702, USA
    J Clin Oncol 29:832-8. 2011
  6. ncbi A novel technique for the enrichment of primary ovarian cancer cells
    John K Chan
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of California, San Francisco, UCSF Comprehensive Cancer Center, 94143 1702, USA
    Am J Obstet Gynecol 197:507.e1-5. 2007
  7. ncbi Racial disparities in surgical treatment and survival of epithelial ovarian cancer in United States
    John K Chan
    Division of Gynecologic Oncology, Department of Obsetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco School of Medicine, UCSF Comprehensive Cancer Center, San Francisco, CA 94143 1702, USA
    J Surg Oncol 97:103-7. 2008
  8. ncbi The outcomes of 27,063 women with unstaged endometrioid uterine cancer
    John K Chan
    Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco School of Medicine, University of California, San Francisco Comprehensive Cancer Center, San Francisco, CA 94143, USA
    Gynecol Oncol 106:282-8. 2007
  9. ncbi Factors associated with the suboptimal treatment of women less than 55 years of age with early-stage ovarian cancer
    John K Chan
    Division of Gynecologic Oncology, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco School of Medicine, UCSF Comprehensive Cancer Center, 94143 1702, USA
    Gynecol Oncol 108:95-9. 2008
  10. ncbi Role of complete lymphadenectomy in endometrioid uterine cancer
    John K Chan
    University of California, San Francisco Comprehensive Cancer Center, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco School of Medicine, San Francisco, CA, USA
    Lancet Oncol 8:831-41. 2007

Collaborators

Detail Information

Publications59

  1. ncbi Influence of the gynecologic oncologist on the survival of ovarian cancer patients
    John K Chan
    Division of Gynecologic Oncology, Department of Obstetrics, University of California, San Francisco School of Medicine, San Francisco Comprehensive Cancer Center, San Francisco, California 94143 1702, USA
    Obstet Gynecol 109:1342-50. 2007
    ..To estimate the influence of gynecologic oncologists on the treatment and outcome of patients with ovarian cancer...
  2. ncbi Prognostic factors for high-risk early-stage epithelial ovarian cancer: a Gynecologic Oncology Group study
    John K Chan
    Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco School of Medicine, UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, California 94143 1702, USA
    Cancer 112:2202-10. 2008
    ..The purpose was to identify the factors predictive of recurrence and survival in patients with high-risk (stage I, grade 3; stage IC, stage II, or clear cell) epithelial ovarian cancer after adjuvant therapy...
  3. ncbi Analysis of phase II studies on targeted agents and subsequent phase III trials: what are the predictors for success?
    John K Chan
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of California, San Francisco, UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA 94143 1702, USA
    J Clin Oncol 26:1511-8. 2008
    ....
  4. ncbi Prognostic factors and risk of extrauterine metastases in 3867 women with grade 1 endometrioid corpus cancer
    John K Chan
    Division of Gynecologic Oncology, Department of Obstetrics, Gynecology, and Reproductive Services, University of California, San Francisco School of Medicine, Helen Diller Family Comprehensive Cancer Center, 94143 1702, USA
    Am J Obstet Gynecol 198:216.e1-5. 2008
    ..The purpose of this study was to evaluate the role of surgical staging in patients with grade 1 endometrioid uterine cancer...
  5. ncbi Influence of gynecologic oncologists on the survival of patients with endometrial cancer
    John K Chan
    University of California, San Francisco UCSF School of Medicine, UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA 94143 1702, USA
    J Clin Oncol 29:832-8. 2011
    ..Therefore, we propose to determine the influence of gynecologic oncologists on the treatment and survival of patients with endometrial cancer...
  6. ncbi A novel technique for the enrichment of primary ovarian cancer cells
    John K Chan
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of California, San Francisco, UCSF Comprehensive Cancer Center, 94143 1702, USA
    Am J Obstet Gynecol 197:507.e1-5. 2007
    ..We describe an efficient and effective method of enriching ovarian tumor cells from ascitic fluid using an immunomagnetic-based method...
  7. ncbi Racial disparities in surgical treatment and survival of epithelial ovarian cancer in United States
    John K Chan
    Division of Gynecologic Oncology, Department of Obsetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco School of Medicine, UCSF Comprehensive Cancer Center, San Francisco, CA 94143 1702, USA
    J Surg Oncol 97:103-7. 2008
    ..To compare the racial differences in treatment and survival of epithelial ovarian cancer patients...
  8. ncbi The outcomes of 27,063 women with unstaged endometrioid uterine cancer
    John K Chan
    Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco School of Medicine, University of California, San Francisco Comprehensive Cancer Center, San Francisco, CA 94143, USA
    Gynecol Oncol 106:282-8. 2007
    ..Over two-thirds of patients with endometrioid uterine cancer in the Surveillance, Epidemiology and End Results program from 1988 to 2001 did not undergo a lymphadenectomy. These patients were compared to those who had a lymphadenectomy...
  9. ncbi Factors associated with the suboptimal treatment of women less than 55 years of age with early-stage ovarian cancer
    John K Chan
    Division of Gynecologic Oncology, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco School of Medicine, UCSF Comprehensive Cancer Center, 94143 1702, USA
    Gynecol Oncol 108:95-9. 2008
    ..A significant number of young patients with early-stage ovarian cancer did not receive chemotherapy based on standard practice guidelines. We investigated factors associated with the suboptimal treatment in these women...
  10. ncbi Role of complete lymphadenectomy in endometrioid uterine cancer
    John K Chan
    University of California, San Francisco Comprehensive Cancer Center, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco School of Medicine, San Francisco, CA, USA
    Lancet Oncol 8:831-41. 2007
    ..Moreover, we discuss the complications associated with lymphadenectomy and identify subsets of low-risk patients who might not need to undergo this procedure...
  11. ncbi The potential therapeutic role of lymph node resection in epithelial ovarian cancer: a study of 13918 patients
    J K Chan
    Division of Gynecologic Oncology, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco School of Medicine, 1600 Divisadero Street, Box 1702, San Francisco, CA 94143, USA
    Br J Cancer 96:1817-22. 2007
    ..The extent of lymphadenectomy is associated with an improved disease-specific survival of women with advanced epithelial ovarian cancer...
  12. ncbi The treatment and outcomes of early-stage epithelial ovarian cancer: have we made any progress?
    Jk Chan
    Division of Gynecologic Oncology, Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco School of Medicine, 1600 Divisadero Street, Box 1702, San Francisco, CA 94143, USA
    Br J Cancer 98:1191-6. 2008
    ..The marginal improvement in survival demonstrated over time is potentially attributed to the increased use of staging procedures with lymphadenectomy...
  13. ncbi Do clear cell ovarian carcinomas have poorer prognosis compared to other epithelial cell types? A study of 1411 clear cell ovarian cancers
    John K Chan
    Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco School of Medicine, UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA 94143 1702, USA
    Gynecol Oncol 109:370-6. 2008
    ..To compare the clinico-pathologic characteristics and survival of women with clear cell versus other epithelial ovarian cancers...
  14. ncbi Survival after recurrence in early-stage high-risk epithelial ovarian cancer: a Gynecologic Oncology Group study
    John K Chan
    Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, Division of Gynecologic Oncology, San Francisco School of Medicine, UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA 94143 1702, USA
    Gynecol Oncol 116:307-11. 2010
    ..This study aimed to evaluate the clinical outcome of recurrent early-stage high-risk epithelial ovarian cancer patients...
  15. ncbi The influence of conservative surgical practices for malignant ovarian germ cell tumors
    John K Chan
    Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco School of Medicine, UCSF Helen Diller Family, Comprehensive Cancer Center, San Francisco, California 94143 1702, USA
    J Surg Oncol 98:111-6. 2008
    ..To evaluate demographics, survival, and surgical trends for patients with malignant ovarian germ cell tumors...
  16. ncbi The potential benefit of 6 vs. 3 cycles of chemotherapy in subsets of women with early-stage high-risk epithelial ovarian cancer: an exploratory analysis of a Gynecologic Oncology Group study
    John K Chan
    Division of Gynecologic Oncology, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco School of Medicine, UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA 94143 1702, USA
    Gynecol Oncol 116:301-6. 2010
    ..three cycles of chemotherapy. We proposed to identify subsets of patients who may benefit from more cycles of chemotherapy...
  17. ncbi Endometrial stromal sarcoma: a population-based analysis
    J K Chan
    Department of Obstetrics, Gynecology, and Reproductive Sciences, San Francisco School of Medicine, UCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA 94143, USA
    Br J Cancer 99:1210-5. 2008
    ..Ovarian-sparing surgeries may be considered in younger patients with early-stage disease...
  18. ncbi Patterns and progress in ovarian cancer over 14 years
    John K Chan
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford Cancer Center, Stanford, California 94305, USA
    Obstet Gynecol 108:521-8. 2006
    ..To estimate the change in survival rates of women with ovarian cancer during the past 14 years...
  19. ncbi Impact of adjuvant therapy on survival of patients with early-stage uterine papillary serous carcinoma
    Chad A Hamilton
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Int J Radiat Oncol Biol Phys 63:839-44. 2005
    ..001) remained as independent prognostic factors for improved survival. CONCLUSION: Adjuvant therapy with chemotherapy or radiotherapy improves the survival of women with early-stage uterine papillary serous carcinoma...
  20. ncbi Trends in demographic and clinical characteristics in women diagnosed with corpus cancer and their potential impact on the increasing number of deaths
    Stefanie M Ueda
    Division of Gynecologic Oncology, Department of Obstetrics, Gynecology, and Reproductive Sciences, UCSF, School of Medicine and Comprehensive Cancer Center, San Francisco, CA 94143 1702, USA
    Am J Obstet Gynecol 198:218.e1-6. 2008
    ..The purpose of this study was to determine factors responsible for the increasing number of deaths from corpus cancer over three time periods...
  21. ncbi Stages III and IV invasive epithelial ovarian carcinoma in younger versus older women: what prognostic factors are important?
    John K Chan
    Division of Gynecologic Oncology, Chao Family Comprehensive Cancer Center, University of California, Orange, California, USA
    Obstet Gynecol 102:156-61. 2003
    ..Clinical and pathologic factors responsible for survival differences between the two groups were also determined...
  22. ncbi Therapeutic role of lymph node resection in endometrioid corpus cancer: a study of 12,333 patients
    John K Chan
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford Cancer Center, Stanford, California 94305, USA
    Cancer 107:1823-30. 2006
    ..The purpose of the current study was to determine the potential therapeutic role of lymphadenectomy in women with endometrioid corpus cancer...
  23. ncbi Prognostic factors for uterine cancer in reproductive-aged women
    Nita Karnik Lee
    Division of Gynecologic Oncology, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco, California 94143, USA
    Obstet Gynecol 109:655-62. 2007
    ..To determine the prognostic factors that influence the survival of younger women diagnosed with uterine cancer...
  24. ncbi The benefit of adjuvant radiation therapy in single-node-positive squamous cell vulvar carcinoma
    Anand Parthasarathy
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford Cancer Center, 875 Blake Wilbur Drive, MC 5827, Stanford, CA 94305, USA
    Gynecol Oncol 103:1095-9. 2006
    ..06). CONCLUSION: Our data suggest that adjuvant radiotherapy may improve the disease-specific survival of patients with single-node-positive vulvar cancer who underwent a less extensive lymph node resection (<or=12 nodes removed)...
  25. ncbi Safety and efficacy of thalidomide in recurrent epithelial ovarian and peritoneal carcinoma
    John K Chan
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Stanford University School of Medicine, 300 Pasteur Drive, Room HH333, Stanford, CA, USA
    Gynecol Oncol 103:919-23. 2006
    ..07). CONCLUSION: Our study demonstrates the safety, tolerability, and potential efficacy of Thalidomide in recurrent and refractory epithelial ovarian cancers. Additional clinical trials are warranted...
  26. ncbi The effect of adjuvant chemotherapy versus whole abdominopelvic radiation on the survival of patients with advanced stage uterine papillary serous carcinoma
    Chad A Hamilton
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Gynecol Oncol 103:679-83. 2006
    ..Given the overall poor prognosis of these patients, new treatment modalities are warranted...
  27. ncbi Small cell carcinoma of the cervix: treatment and survival outcomes of 188 patients
    Joshua G Cohen
    Division of Gynecologic Oncology, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, USA
    Am J Obstet Gynecol 203:347.e1-6. 2010
    ..To determine the clinicopathologic factors associated with survival in neuroendocrine small cell cervical cancer patients...
  28. ncbi Adjuvant radiation therapy in stage III node-positive uterine cancer
    Seraina Schmid
    Division of Gynecologic Oncology, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco School of Medicine, UCSF Helen Diller Family Comprehensive Cancer Center, 1600 Divisadero Street, Box 1702, San Francisco, CA 94143 1702, USA
    Gynecol Oncol 115:239-43. 2009
    ..To determine the association of adjuvant radiotherapy and outcomes of women with stage III node-positive uterine cancer...
  29. ncbi Borderline ovarian tumors in reproductive-age women. Fertility-sparing surgery and outcome
    John K Chan
    Division of Gynecologic Oncology, Chao Family Comprehensive Cancer Center, University of California, Irvine, Medical Center, Orange, USA
    J Reprod Med 48:756-60. 2003
    ..The median follow-up was 80 months (range, 4-157). CONCLUSION: Conservative surgery for borderline ovarian tumors should be considered for women in the reproductive age group who desire preservation of fertility...
  30. ncbi Prognostic factors responsible for survival in sex cord stromal tumors of the ovary--an analysis of 376 women
    Mallory Zhang
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford Cancer Center, 875 Blake Wilbur Drive, MC 5827, Stanford, CA 94305, USA
    Gynecol Oncol 104:396-400. 2007
    ..To evaluate prognostic factors that impact on the survival of women with ovarian sex cord stromal tumors (SCST)...
  31. ncbi Survival outcomes in patients with recurrent ovarian cancer who were treated with chemoresistance assay-guided chemotherapy
    Vera Loizzi
    Division of Gynecologic Oncology, Chao Family Comprehensive Cancer Center, University of California-Irvine Medical Center, 101 The City Drive, Orange, CA 92868, USA
    Am J Obstet Gynecol 189:1301-7. 2003
    ..Randomized, prospective, controlled trials are needed...
  32. ncbi Vulvar melanoma: a multivariable analysis of 644 patients
    Valerie E Sugiyama
    Division of Gynecologic Oncology, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Francisco School of Medicine, UCSF Comprehensive Cancer Center, 1600 Divisadero Street, San Francisco, CA, USA
    Obstet Gynecol 110:296-301. 2007
    ..To determine the prognostic factors associated with the survival of vulvar melanoma patients...
  33. ncbi Prognostic factors responsible for survival in sex cord stromal tumors of the ovary--a multivariate analysis
    John K Chan
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Stanford University School of Medicine, 300 Pasteur Drive, HH333, Stanford Cancer Center, Stanford, CA 94305, USA
    Gynecol Oncol 96:204-9. 2005
    ..To evaluate prognostic factors that impacts the survival of women with sex cord stromal tumors of the ovary (SCST)...
  34. ncbi Lymphadenectomy in endometrioid uterine cancer staging: how many lymph nodes are enough? A study of 11,443 patients
    John K Chan
    Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California at San Francisco School of Medicine, University of California, San Francisco Comprehensive Cancer Center, California 94143 1702, USA
    Cancer 109:2454-60. 2007
    ....
  35. ncbi Adjuvant radiotherapy in incompletely staged IC and II endometrioid uterine cancer
    Anand Parthasarathy
    Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco, California 94143 1702, USA
    Obstet Gynecol 110:1237-43. 2007
    ..To estimate if adjuvant radiotherapy improves the disease-specific survival of patients with clinical stage IC and II endometrioid corpus cancer who did not undergo lymphadenectomy...
  36. ncbi Cost effectiveness of a test to detect metastases for endometrial cancer
    Laura J Havrilesky
    Division of Gynecologic Oncology, Duke University Medical Center, Durham, NC 27710, USA
    Gynecol Oncol 112:526-30. 2009
    ..To estimate the potential cost-effectiveness of a hypothetical test to screen for lymph node metastases in women with newly diagnosed, apparent early stage endometrial cancer...
  37. ncbi Association of lymphadenectomy and survival in stage I ovarian cancer patients
    John K Chan
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Stanford Cancer Center, Stanford University School of Medicine, Stanford, CA 94305, USA
    Obstet Gynecol 109:12-9. 2007
    ..To estimate the survival impact of lymphadenectomy in women diagnosed with clinical stage I ovarian cancer...
  38. ncbi Margin distance and other clinico-pathologic prognostic factors in vulvar carcinoma: a multivariate analysis
    John K Chan
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Stanford Cancer Center, 875 Blake Wilbur Drive, MC 5827, Stanford, CA 94305, USA
    Gynecol Oncol 104:636-41. 2007
    ..To determine the importance of margin status and other prognostic factors associated with the recurrence and survival of patients with squamous cell vulvar carcinoma...
  39. ncbi Prognostic factors in neuroendocrine small cell cervical carcinoma: a multivariate analysis
    John K Chan
    Division of Gynecologic Oncology, The Chao Family Comprehensive Cancer Center, University of California-Irvine Medical Center, Orange, California 92868, USA
    Cancer 97:568-74. 2003
    ..The role of primary or postoperative radiation with or without chemotherapy is unclear and yields uniformly poor results, particularly in patients with advanced lesions. Clinical trials are needed...
  40. ncbi Improved survival of Asians with corpus cancer compared with whites: an analysis of underlying factors
    Mallory M Zhang
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Stanford Cancer Center, Stanford University School of Medicine, CA 94305, USA
    Obstet Gynecol 107:329-35. 2006
    ..level of evidence: ii-2...
  41. ncbi Patients with malignancy requiring urgent therapy: CASE 3. Tumor lysis syndrome associated with chemotherapy in ovarian cancer
    John K Chan
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, CA, USA
    J Clin Oncol 23:6794-5. 2005
  42. ncbi Conservative clitoral preservation surgery in the treatment of vulvar squamous cell carcinoma
    John K Chan
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, CA 94305-5317, USA
    Gynecol Oncol 95:152-6. 2004
    ..CONCLUSION: Clitoral-sparing vulvar cancer surgery does not compromise the rate of loco-regional control in patients and may be offered to selected women...
  43. ncbi Significance of comprehensive surgical staging in noninvasive papillary serous carcinoma of the endometrium
    John K Chan
    Department of Obstetrics and Gynecology, University of California, Irvine-Medical Center, 101 The City Drive, Orange, CA 92868, USA
    Gynecol Oncol 90:181-5. 2003
    ..Thus, women with noninvasive UPSC should undergo a comprehensive staging procedure including omental sampling to determine the extent of disease...
  44. ncbi Safety and efficacy of lenalidomide (Revlimid) in recurrent ovarian and primary peritoneal carcinoma
    Mallory M Zhang
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Stanford University School of Medicine, 300 Pasteur Drive, Room HH333, Stanford, CA 94305 5317, USA
    Gynecol Oncol 105:194-8. 2007
    ..The secondary objective is to evaluate the efficacy profile and quality of life (QOL) parameters in patients receiving this treatment...
  45. ncbi Suppression of ovarian cancer cell tumorigenicity and evasion of Cisplatin resistance using a truncated epidermal growth factor receptor in a rat model
    John K Chan
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Stanford Cancer Center, 300 Pasteur Drive HH333, Stanford, CA 94305 5317, USA
    Cancer Res 65:3243-8. 2005
    ..Thus, EGFR blockade may ultimately prove to be a useful therapeutic tool in the treatment of cisplatin-sensitive and cisplatin-resistant ovarian cancers...
  46. ncbi Mast cell density, angiogenesis, blood clotting, and prognosis in women with advanced ovarian cancer
    John K Chan
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Stanford University School of Medicine, 300 Pasteur Dr HH333, Stanford, CA 94305 5317, USA
    Gynecol Oncol 99:20-5. 2005
    ..To determine clinical or biological associations between mast cell density, blood clotting, angiogenesis, and survival of patients with advanced ovarian cancer...
  47. ncbi Clinicopathologic features of six cases of primary cervical lymphoma
    John K Chan
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Stanford Cancer Center, Stanford University School of Medicine, Stanford, CA, USA
    Am J Obstet Gynecol 193:866-72. 2005
    ..Primary lymphoma of the uterine cervix is rare, with less than 60 cases reported. We present a series of 6 patients with cervical lymphoma and review the literature...
  48. ncbi Clinical aspects of uterine papillary serous carcinoma
    Chad A Hamilton
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Walter Reed Army Medical Center, Washington, District of Columbia, USA
    Curr Opin Obstet Gynecol 20:26-33. 2008
    ..We review the demographic and clinicopathologic characteristics, and prognosis of women diagnosed with uterine papillary serous carcinoma, with a focus on clinical management...
  49. ncbi Oral altretamine used as salvage therapy in recurrent ovarian cancer
    John K Chan
    Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, CA 94305 5317, USA
    Gynecol Oncol 92:368-71. 2004
    ..Altretamine has reported efficacy in the treatment of recurrent ovarian cancer following platinum-based therapy. This report presents the cases of two long-term survivors with recurrent ovarian cancer given oral altretamine...
  50. ncbi Breast cancer followed by corpus cancer: is there a higher risk for aggressive histologic subtypes?
    John K Chan
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Stanford University Medical Center, Stanford Cancer Center 875 Blake Wilbur Drive, MC 5827, Stanford, CA 94305, USA
    Gynecol Oncol 102:508-12. 2006
    ..To analyze corpus cancer patients with a breast cancer history for risk of developing aggressive uterine histologic types...
  51. ncbi Enhanced killing of primary ovarian cancer by retargeting autologous cytokine-induced killer cells with bispecific antibodies: a preclinical study
    John K Chan
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Stanford Cancer Center, Stanford University, Stanford, California, USA
    Clin Cancer Res 12:1859-67. 2006
    ..Bispecific antibodies significantly enhanced the cytotoxicity of CIK cells in primary ovarian cancer cells and in our in vivo mouse model. The mechanism of cytolysis seems to be mediated in part by the NKG2D receptor...
  52. ncbi Degranulating mast cells in fibrotic regions of human tumors and evidence that mast cell heparin interferes with the growth of tumor cells through a mechanism involving fibroblasts
    Michael Samoszuk
    Department of Pathology and Laboratory Medicine, University of California, Irvine, California, USA
    BMC Cancer 5:121. 2005
    ..The purpose of this study was to test the hypothesis that mast cells that are present in fibrotic regions of cancer can suppress the growth of tumor cells through an indirect mechanism involving peri-tumoral fibroblasts...
  53. ncbi A modified technique for insertion of intraperitoneal port for chemotherapy
    Wen-Shiung Liou
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Stanford Cancer Center, Stanford University School of Medicine, Stanford, California 94305-5317, USA
    J Surg Oncol 90:247-8. 2005
    ..An effective method that provides a reliable access to the IP cavity is needed. In this report, we describe a novel technique of IP port placement that may prevent access problems and decrease patient discomfort...
  54. ncbi Juvenile granulosa cell tumor of the ovary associated with tuberous sclerosis
    Hongyan Guo
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Stanford University School of Medicine, 300 Pasteur Drive HH333, CA 94305, USA
    Gynecol Oncol 102:118-20. 2006
    ..She is currently free of disease 8 years after her recurrence. CONCLUSION: Treatment options and a review of the literature pertaining to juvenile ovarian granulosa cell tumors and tuberous sclerosis are discussed...
  55. ncbi Innovations in fertility preservation for patients with gynecologic cancers
    Wen-Shiung Liou
    Division of Gynecologic Oncology, Department of Gynecology and Obstetrics, Stanford University School of Medicine, Palo Alto, California, USA
    Fertil Steril 84:1561-73. 2005
    ..For some women with gynecologic cancers, fertility-sparing treatment might be appropriate...
  56. ncbi Differences in prognostic molecular markers between women over and under 45 years of age with advanced ovarian cancer
    John K Chan
    Division of Obstetrics and Gynecology, Stanford University School of Medicine, California, USA
    Clin Cancer Res 10:8538-43. 2004
    ..Lower MVD was an independent prognostic factor for decreased survival. Lower frequency of neovascularization in these cancers may contribute to the decreased survival observed in women >45 years of age...
  57. ncbi Laparoscopic photodynamic diagnosis of ovarian cancer using 5-aminolevulinic acid in a rat model
    John K Chan
    Beckman Laser Institute, University of California-Irvine, Irvine, CA 92612, USA
    Gynecol Oncol 87:64-70. 2002
    ..Human trials are indicated...
  58. ncbi Prognostic factors and survival in 1396 patients with uterine leiomyosarcomas: emphasis on impact of lymphadenectomy and oophorectomy
    Daniel S Kapp
    Division of Radiation Therapy, Department of Radiation Oncology, Stanford University School of Medicine, Stanford Cancer Center, Stanford, California 94305 5847, USA
    Cancer 112:820-30. 2008
    ....
  59. ncbi Outcomes of women with metachronous breast and ovarian carcinomas
    Wen-Shiung Liou
    Department of Gynecology and Obstetrics, Stanford Cancer Center, Stanford University School of Medicine, 875 Blake Wilbur Drive, MC 5827, Stanford, CA 94305, USA
    Gynecol Oncol 103:190-4. 2006
    ..Since half of the women had their second cancer beyond 5 years, continued surveillance of these high risk patients is recommended...