Jk Chan

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint MiR-378 as a biomarker for response to anti-angiogenic treatment in ovarian cancer
    John K Chan
    Division of Gynecologic Oncology, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco School of Medicine, 1600 Divisadero Street, Box 1702, San Francisco, CA 94143, USA Palo Alto Medical Foundation Research Institute, 795 El Camino Real, Palo Alto, CA 94301, USA Electronic address
    Gynecol Oncol 133:568-74. 2014
  2. pmc The impact of the absolute number and ratio of positive lymph nodes on survival of endometrioid uterine cancer patients
    J K Chan
    Division of Gynecologic Oncology, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco School of Medicine, San Francisco Comprehensive Cancer Center, San Francisco, CA 94143, USA
    Br J Cancer 97:605-11. 2007
  3. doi request reprint The inhibition of miR-21 promotes apoptosis and chemosensitivity in ovarian cancer
    John K Chan
    Division of Gynecologic Oncology, Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco School of Medicine, UCSF Helen Diller Family Comprehensive Cancer Center, 1600 Divisadero Street, Box 1702, San Francisco, CA 94143, USA Electronic address
    Gynecol Oncol 132:739-44. 2014
  4. ncbi request reprint Influence of the gynecologic oncologist on the survival of ovarian cancer patients
    John K Chan
    Division of Gynecologic Oncology, Department of Obstetrics, University of California, San Francisco School of Medicine, San Francisco Comprehensive Cancer Center, San Francisco, California 94143 1702, USA
    Obstet Gynecol 109:1342-50. 2007
  5. doi request reprint Influence of gynecologic oncologists on the survival of patients with endometrial cancer
    John K Chan
    University of California, San Francisco UCSF School of Medicine, UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA 94143 1702, USA
    J Clin Oncol 29:832-8. 2011
  6. doi request reprint Prognostic factors and risk of extrauterine metastases in 3867 women with grade 1 endometrioid corpus cancer
    John K Chan
    Division of Gynecologic Oncology, Department of Obstetrics, Gynecology, and Reproductive Services, University of California, San Francisco School of Medicine, Helen Diller Family Comprehensive Cancer Center, 94143 1702, USA
    Am J Obstet Gynecol 198:216.e1-5. 2008
  7. pmc The potential therapeutic role of lymph node resection in epithelial ovarian cancer: a study of 13918 patients
    J K Chan
    Division of Gynecologic Oncology, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco School of Medicine, 1600 Divisadero Street, Box 1702, San Francisco, CA 94143, USA
    Br J Cancer 96:1817-22. 2007
  8. ncbi request reprint A novel technique for the enrichment of primary ovarian cancer cells
    John K Chan
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of California, San Francisco, UCSF Comprehensive Cancer Center, 94143 1702, USA
    Am J Obstet Gynecol 197:507.e1-5. 2007
  9. ncbi request reprint Racial disparities in surgical treatment and survival of epithelial ovarian cancer in United States
    John K Chan
    Division of Gynecologic Oncology, Department of Obsetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco School of Medicine, UCSF Comprehensive Cancer Center, San Francisco, CA 94143 1702, USA
    J Surg Oncol 97:103-7. 2008
  10. ncbi request reprint Factors associated with the suboptimal treatment of women less than 55 years of age with early-stage ovarian cancer
    John K Chan
    Division of Gynecologic Oncology, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco School of Medicine, UCSF Comprehensive Cancer Center, 94143 1702, USA
    Gynecol Oncol 108:95-9. 2008

Detail Information

Publications62

  1. ncbi request reprint MiR-378 as a biomarker for response to anti-angiogenic treatment in ovarian cancer
    John K Chan
    Division of Gynecologic Oncology, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco School of Medicine, 1600 Divisadero Street, Box 1702, San Francisco, CA 94143, USA Palo Alto Medical Foundation Research Institute, 795 El Camino Real, Palo Alto, CA 94301, USA Electronic address
    Gynecol Oncol 133:568-74. 2014
    ..To determine the role of miR-378 as a biomarker for anti-angiogenic therapy response in ovarian cancer...
  2. pmc The impact of the absolute number and ratio of positive lymph nodes on survival of endometrioid uterine cancer patients
    J K Chan
    Division of Gynecologic Oncology, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco School of Medicine, San Francisco Comprehensive Cancer Center, San Francisco, CA 94143, USA
    Br J Cancer 97:605-11. 2007
    ..The stratification of node-positive uterine cancer for prognostic and treatment purposes warrants further investigation...
  3. doi request reprint The inhibition of miR-21 promotes apoptosis and chemosensitivity in ovarian cancer
    John K Chan
    Division of Gynecologic Oncology, Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco School of Medicine, UCSF Helen Diller Family Comprehensive Cancer Center, 1600 Divisadero Street, Box 1702, San Francisco, CA 94143, USA Electronic address
    Gynecol Oncol 132:739-44. 2014
    ..MicroRNAs have been implicated in tumorigenesis, drug resistance, and prognosis in cancer. We investigated the role of microRNA-21 (miR-21) in regulating ovarian cancer drug resistance...
  4. ncbi request reprint Influence of the gynecologic oncologist on the survival of ovarian cancer patients
    John K Chan
    Division of Gynecologic Oncology, Department of Obstetrics, University of California, San Francisco School of Medicine, San Francisco Comprehensive Cancer Center, San Francisco, California 94143 1702, USA
    Obstet Gynecol 109:1342-50. 2007
    ..To estimate the influence of gynecologic oncologists on the treatment and outcome of patients with ovarian cancer...
  5. doi request reprint Influence of gynecologic oncologists on the survival of patients with endometrial cancer
    John K Chan
    University of California, San Francisco UCSF School of Medicine, UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA 94143 1702, USA
    J Clin Oncol 29:832-8. 2011
    ..Therefore, we propose to determine the influence of gynecologic oncologists on the treatment and survival of patients with endometrial cancer...
  6. doi request reprint Prognostic factors and risk of extrauterine metastases in 3867 women with grade 1 endometrioid corpus cancer
    John K Chan
    Division of Gynecologic Oncology, Department of Obstetrics, Gynecology, and Reproductive Services, University of California, San Francisco School of Medicine, Helen Diller Family Comprehensive Cancer Center, 94143 1702, USA
    Am J Obstet Gynecol 198:216.e1-5. 2008
    ..The purpose of this study was to evaluate the role of surgical staging in patients with grade 1 endometrioid uterine cancer...
  7. pmc The potential therapeutic role of lymph node resection in epithelial ovarian cancer: a study of 13918 patients
    J K Chan
    Division of Gynecologic Oncology, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco School of Medicine, 1600 Divisadero Street, Box 1702, San Francisco, CA 94143, USA
    Br J Cancer 96:1817-22. 2007
    ..The extent of lymphadenectomy is associated with an improved disease-specific survival of women with advanced epithelial ovarian cancer...
  8. ncbi request reprint A novel technique for the enrichment of primary ovarian cancer cells
    John K Chan
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of California, San Francisco, UCSF Comprehensive Cancer Center, 94143 1702, USA
    Am J Obstet Gynecol 197:507.e1-5. 2007
    ..We describe an efficient and effective method of enriching ovarian tumor cells from ascitic fluid using an immunomagnetic-based method...
  9. ncbi request reprint Racial disparities in surgical treatment and survival of epithelial ovarian cancer in United States
    John K Chan
    Division of Gynecologic Oncology, Department of Obsetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco School of Medicine, UCSF Comprehensive Cancer Center, San Francisco, CA 94143 1702, USA
    J Surg Oncol 97:103-7. 2008
    ..To compare the racial differences in treatment and survival of epithelial ovarian cancer patients...
  10. ncbi request reprint Factors associated with the suboptimal treatment of women less than 55 years of age with early-stage ovarian cancer
    John K Chan
    Division of Gynecologic Oncology, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco School of Medicine, UCSF Comprehensive Cancer Center, 94143 1702, USA
    Gynecol Oncol 108:95-9. 2008
    ..A significant number of young patients with early-stage ovarian cancer did not receive chemotherapy based on standard practice guidelines. We investigated factors associated with the suboptimal treatment in these women...
  11. ncbi request reprint Role of complete lymphadenectomy in endometrioid uterine cancer
    John K Chan
    University of California, San Francisco Comprehensive Cancer Center, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco School of Medicine, San Francisco, CA, USA
    Lancet Oncol 8:831-41. 2007
    ..Moreover, we discuss the complications associated with lymphadenectomy and identify subsets of low-risk patients who might not need to undergo this procedure...
  12. ncbi request reprint The outcomes of 27,063 women with unstaged endometrioid uterine cancer
    John K Chan
    Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco School of Medicine, University of California, San Francisco Comprehensive Cancer Center, San Francisco, CA 94143, USA
    Gynecol Oncol 106:282-8. 2007
    ..Over two-thirds of patients with endometrioid uterine cancer in the Surveillance, Epidemiology and End Results program from 1988 to 2001 did not undergo a lymphadenectomy. These patients were compared to those who had a lymphadenectomy...
  13. doi request reprint Analysis of phase II studies on targeted agents and subsequent phase III trials: what are the predictors for success?
    John K Chan
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of California, San Francisco, UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA 94143 1702, USA
    J Clin Oncol 26:1511-8. 2008
    ....
  14. ncbi request reprint Prognostic factors for high-risk early-stage epithelial ovarian cancer: a Gynecologic Oncology Group study
    John K Chan
    Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco School of Medicine, UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, California 94143 1702, USA
    Cancer 112:2202-10. 2008
    ..The purpose was to identify the factors predictive of recurrence and survival in patients with high-risk (stage I, grade 3; stage IC, stage II, or clear cell) epithelial ovarian cancer after adjuvant therapy...
  15. pmc The treatment and outcomes of early-stage epithelial ovarian cancer: have we made any progress?
    Jk Chan
    Division of Gynecologic Oncology, Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco School of Medicine, 1600 Divisadero Street, Box 1702, San Francisco, CA 94143, USA
    Br J Cancer 98:1191-6. 2008
    ..The marginal improvement in survival demonstrated over time is potentially attributed to the increased use of staging procedures with lymphadenectomy...
  16. doi request reprint Do clear cell ovarian carcinomas have poorer prognosis compared to other epithelial cell types? A study of 1411 clear cell ovarian cancers
    John K Chan
    Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco School of Medicine, UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA 94143 1702, USA
    Gynecol Oncol 109:370-6. 2008
    ..To compare the clinico-pathologic characteristics and survival of women with clear cell versus other epithelial ovarian cancers...
  17. pmc The influence of conservative surgical practices for malignant ovarian germ cell tumors
    John K Chan
    Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco School of Medicine, UCSF Helen Diller Family, Comprehensive Cancer Center, San Francisco, California 94143 1702, USA
    J Surg Oncol 98:111-6. 2008
    ..To evaluate demographics, survival, and surgical trends for patients with malignant ovarian germ cell tumors...
  18. pmc Endometrial stromal sarcoma: a population-based analysis
    J K Chan
    Department of Obstetrics, Gynecology, and Reproductive Sciences, San Francisco School of Medicine, UCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA 94143, USA
    Br J Cancer 99:1210-5. 2008
    ..Ovarian-sparing surgeries may be considered in younger patients with early-stage disease...
  19. doi request reprint The potential benefit of 6 vs. 3 cycles of chemotherapy in subsets of women with early-stage high-risk epithelial ovarian cancer: an exploratory analysis of a Gynecologic Oncology Group study
    John K Chan
    Division of Gynecologic Oncology, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco School of Medicine, UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA 94143 1702, USA
    Gynecol Oncol 116:301-6. 2010
    ..three cycles of chemotherapy. We proposed to identify subsets of patients who may benefit from more cycles of chemotherapy...
  20. doi request reprint Survival after recurrence in early-stage high-risk epithelial ovarian cancer: a Gynecologic Oncology Group study
    John K Chan
    Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, Division of Gynecologic Oncology, San Francisco School of Medicine, UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA 94143 1702, USA
    Gynecol Oncol 116:307-11. 2010
    ..This study aimed to evaluate the clinical outcome of recurrent early-stage high-risk epithelial ovarian cancer patients...
  21. ncbi request reprint Patterns and progress in ovarian cancer over 14 years
    John K Chan
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford Cancer Center, Stanford, California 94305, USA
    Obstet Gynecol 108:521-8. 2006
    ..To estimate the change in survival rates of women with ovarian cancer during the past 14 years...
  22. ncbi request reprint Impact of adjuvant therapy on survival of patients with early-stage uterine papillary serous carcinoma
    Chad A Hamilton
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Int J Radiat Oncol Biol Phys 63:839-44. 2005
    ..To determine the efficacy of adjuvant therapy in patients with early-stage uterine papillary serous carcinoma...
  23. ncbi request reprint Therapeutic role of lymph node resection in endometrioid corpus cancer: a study of 12,333 patients
    John K Chan
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford Cancer Center, Stanford, California 94305, USA
    Cancer 107:1823-30. 2006
    ..The purpose of the current study was to determine the potential therapeutic role of lymphadenectomy in women with endometrioid corpus cancer...
  24. ncbi request reprint Stages III and IV invasive epithelial ovarian carcinoma in younger versus older women: what prognostic factors are important?
    John K Chan
    Division of Gynecologic Oncology, Chao Family Comprehensive Cancer Center, University of California, Orange, California, USA
    Obstet Gynecol 102:156-61. 2003
    ..Clinical and pathologic factors responsible for survival differences between the two groups were also determined...
  25. doi request reprint Trends in demographic and clinical characteristics in women diagnosed with corpus cancer and their potential impact on the increasing number of deaths
    Stefanie M Ueda
    Division of Gynecologic Oncology, Department of Obstetrics, Gynecology, and Reproductive Sciences, UCSF, School of Medicine and Comprehensive Cancer Center, San Francisco, CA 94143 1702, USA
    Am J Obstet Gynecol 198:218.e1-6. 2008
    ..The purpose of this study was to determine factors responsible for the increasing number of deaths from corpus cancer over three time periods...
  26. doi request reprint Small cell carcinoma of the cervix: treatment and survival outcomes of 188 patients
    Joshua G Cohen
    Division of Gynecologic Oncology, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, USA
    Am J Obstet Gynecol 203:347.e1-6. 2010
    ..To determine the clinicopathologic factors associated with survival in neuroendocrine small cell cervical cancer patients...
  27. ncbi request reprint Prognostic factors for uterine cancer in reproductive-aged women
    Nita Karnik Lee
    Division of Gynecologic Oncology, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco, California 94143, USA
    Obstet Gynecol 109:655-62. 2007
    ..To determine the prognostic factors that influence the survival of younger women diagnosed with uterine cancer...
  28. ncbi request reprint Adjuvant radiation therapy in stage III node-positive uterine cancer
    Seraina Schmid
    Division of Gynecologic Oncology, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco School of Medicine, UCSF Helen Diller Family Comprehensive Cancer Center, 1600 Divisadero Street, Box 1702, San Francisco, CA 94143 1702, USA
    Gynecol Oncol 115:239-43. 2009
    ..To determine the association of adjuvant radiotherapy and outcomes of women with stage III node-positive uterine cancer...
  29. ncbi request reprint Safety and efficacy of thalidomide in recurrent epithelial ovarian and peritoneal carcinoma
    John K Chan
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Stanford University School of Medicine, 300 Pasteur Drive, Room HH333, Stanford, CA, USA
    Gynecol Oncol 103:919-23. 2006
    ..Thalidomide is an anti-angiogenesis agent that has shown activity in some solid tumors. We performed a phase I clinical trial to determine the toxicity and potential efficacy of Thalidomide in recurrent epithelial ovarian carcinoma...
  30. ncbi request reprint The effect of adjuvant chemotherapy versus whole abdominopelvic radiation on the survival of patients with advanced stage uterine papillary serous carcinoma
    Chad A Hamilton
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Gynecol Oncol 103:679-83. 2006
    ..To compare the outcomes of stage III and IV uterine papillary serous carcinoma (UPSC) patients treated with platinum-based chemotherapy (PC) versus whole abdominopelvic irradiation (WAPI) after optimal cytoreductive surgery...
  31. ncbi request reprint Borderline ovarian tumors in reproductive-age women. Fertility-sparing surgery and outcome
    John K Chan
    Division of Gynecologic Oncology, Chao Family Comprehensive Cancer Center, University of California, Irvine, Medical Center, Orange, USA
    J Reprod Med 48:756-60. 2003
    ..To evaluate the fertility and survival outcomes in young women with borderline ovarian tumors treated with fertility-sparing surgery...
  32. ncbi request reprint The benefit of adjuvant radiation therapy in single-node-positive squamous cell vulvar carcinoma
    Anand Parthasarathy
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford Cancer Center, 875 Blake Wilbur Drive, MC 5827, Stanford, CA 94305, USA
    Gynecol Oncol 103:1095-9. 2006
    ..To determine if adjuvant radiotherapy improves the survival of women with invasive squamous cell carcinoma of the vulva involving one inguinal node...
  33. ncbi request reprint Vulvar melanoma: a multivariable analysis of 644 patients
    Valerie E Sugiyama
    Division of Gynecologic Oncology, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Francisco School of Medicine, UCSF Comprehensive Cancer Center, 1600 Divisadero Street, San Francisco, CA, USA
    Obstet Gynecol 110:296-301. 2007
    ..To determine the prognostic factors associated with the survival of vulvar melanoma patients...
  34. ncbi request reprint Prognostic factors responsible for survival in sex cord stromal tumors of the ovary--a multivariate analysis
    John K Chan
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Stanford University School of Medicine, 300 Pasteur Drive, HH333, Stanford Cancer Center, Stanford, CA 94305, USA
    Gynecol Oncol 96:204-9. 2005
    ..To evaluate prognostic factors that impacts the survival of women with sex cord stromal tumors of the ovary (SCST)...
  35. ncbi request reprint Survival outcomes in patients with recurrent ovarian cancer who were treated with chemoresistance assay-guided chemotherapy
    Vera Loizzi
    Division of Gynecologic Oncology, Chao Family Comprehensive Cancer Center, University of California Irvine Medical Center, 101 The City Drive, Orange, CA 92868, USA
    Am J Obstet Gynecol 189:1301-7. 2003
    ..The purpose of this study was to determine the outcome of patients with recurrent ovarian carcinoma after extreme drug resistance assay-directed therapy...
  36. ncbi request reprint Adjuvant radiotherapy in incompletely staged IC and II endometrioid uterine cancer
    Anand Parthasarathy
    Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco, California 94143 1702, USA
    Obstet Gynecol 110:1237-43. 2007
    ..To estimate if adjuvant radiotherapy improves the disease-specific survival of patients with clinical stage IC and II endometrioid corpus cancer who did not undergo lymphadenectomy...
  37. ncbi request reprint Lymphadenectomy in endometrioid uterine cancer staging: how many lymph nodes are enough? A study of 11,443 patients
    John K Chan
    Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California at San Francisco School of Medicine, University of California, San Francisco Comprehensive Cancer Center, California 94143 1702, USA
    Cancer 109:2454-60. 2007
    ....
  38. ncbi request reprint Prognostic factors responsible for survival in sex cord stromal tumors of the ovary--an analysis of 376 women
    Mallory Zhang
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford Cancer Center, 875 Blake Wilbur Drive, MC 5827, Stanford, CA 94305, USA
    Gynecol Oncol 104:396-400. 2007
    ..To evaluate prognostic factors that impact on the survival of women with ovarian sex cord stromal tumors (SCST)...
  39. ncbi request reprint Cost effectiveness of a test to detect metastases for endometrial cancer
    Laura J Havrilesky
    Division of Gynecologic Oncology, Duke University Medical Center, Durham, NC 27710, USA
    Gynecol Oncol 112:526-30. 2009
    ..To estimate the potential cost-effectiveness of a hypothetical test to screen for lymph node metastases in women with newly diagnosed, apparent early stage endometrial cancer...
  40. ncbi request reprint Margin distance and other clinico-pathologic prognostic factors in vulvar carcinoma: a multivariate analysis
    John K Chan
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Stanford Cancer Center, 875 Blake Wilbur Drive, MC 5827, Stanford, CA 94305, USA
    Gynecol Oncol 104:636-41. 2007
    ..To determine the importance of margin status and other prognostic factors associated with the recurrence and survival of patients with squamous cell vulvar carcinoma...
  41. ncbi request reprint Association of lymphadenectomy and survival in stage I ovarian cancer patients
    John K Chan
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Stanford Cancer Center, Stanford University School of Medicine, Stanford, CA 94305, USA
    Obstet Gynecol 109:12-9. 2007
    ..To estimate the survival impact of lymphadenectomy in women diagnosed with clinical stage I ovarian cancer...
  42. ncbi request reprint Safety and efficacy of lenalidomide (Revlimid) in recurrent ovarian and primary peritoneal carcinoma
    Mallory M Zhang
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Stanford University School of Medicine, 300 Pasteur Drive, Room HH333, Stanford, CA 94305 5317, USA
    Gynecol Oncol 105:194-8. 2007
    ..The secondary objective is to evaluate the efficacy profile and quality of life (QOL) parameters in patients receiving this treatment...
  43. ncbi request reprint Improved survival of Asians with corpus cancer compared with whites: an analysis of underlying factors
    Mallory M Zhang
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Stanford Cancer Center, Stanford University School of Medicine, CA 94305, USA
    Obstet Gynecol 107:329-35. 2006
    ..To compare the clinicopathologic prognosticators and survival of Asians and whites with corpus cancer...
  44. ncbi request reprint Patients with malignancy requiring urgent therapy: CASE 3. Tumor lysis syndrome associated with chemotherapy in ovarian cancer
    John K Chan
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, CA, USA
    J Clin Oncol 23:6794-5. 2005
  45. ncbi request reprint Prognostic factors in neuroendocrine small cell cervical carcinoma: a multivariate analysis
    John K Chan
    Division of Gynecologic Oncology, The Chao Family Comprehensive Cancer Center, University of California Irvine Medical Center, Orange, California 92868, USA
    Cancer 97:568-74. 2003
    ..The purpose of this study was to evaluate the clinical and pathologic factors associated with survival in patients with neuroendocrine (NE) cervical carcinoma...
  46. ncbi request reprint Significance of comprehensive surgical staging in noninvasive papillary serous carcinoma of the endometrium
    John K Chan
    Department of Obstetrics and Gynecology, University of California, Irvine Medical Center, 101 The City Drive, Orange, CA 92868, USA
    Gynecol Oncol 90:181-5. 2003
    ..Data for analysis were collected from hospital charts, office records, and tumor registry files...
  47. ncbi request reprint Conservative clitoral preservation surgery in the treatment of vulvar squamous cell carcinoma
    John K Chan
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, CA 94305 5317, USA
    Gynecol Oncol 95:152-6. 2004
    ..To determine the safety and efficacy of clitoral-sparing surgery in women with squamous cell carcinoma (SCCA) of the anterior vulva not involving the clitoris...
  48. ncbi request reprint Enhanced killing of primary ovarian cancer by retargeting autologous cytokine-induced killer cells with bispecific antibodies: a preclinical study
    John K Chan
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Stanford Cancer Center, Stanford University, Stanford, California, USA
    Clin Cancer Res 12:1859-67. 2006
    ..Bispecific antibodies significantly enhanced the cytotoxicity of CIK cells in primary ovarian cancer cells and in our in vivo mouse model. The mechanism of cytolysis seems to be mediated in part by the NKG2D receptor...
  49. ncbi request reprint Oral altretamine used as salvage therapy in recurrent ovarian cancer
    John K Chan
    Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, CA 94305 5317, USA
    Gynecol Oncol 92:368-71. 2004
    ..Altretamine has reported efficacy in the treatment of recurrent ovarian cancer following platinum-based therapy. This report presents the cases of two long-term survivors with recurrent ovarian cancer given oral altretamine...
  50. ncbi request reprint Breast cancer followed by corpus cancer: is there a higher risk for aggressive histologic subtypes?
    John K Chan
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Stanford University Medical Center, Stanford Cancer Center 875 Blake Wilbur Drive, MC 5827, Stanford, CA 94305, USA
    Gynecol Oncol 102:508-12. 2006
    ..To analyze corpus cancer patients with a breast cancer history for risk of developing aggressive uterine histologic types...
  51. ncbi request reprint Suppression of ovarian cancer cell tumorigenicity and evasion of Cisplatin resistance using a truncated epidermal growth factor receptor in a rat model
    John K Chan
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Stanford Cancer Center, 300 Pasteur Drive HH333, Stanford, CA 94305 5317, USA
    Cancer Res 65:3243-8. 2005
    ..Thus, EGFR blockade may ultimately prove to be a useful therapeutic tool in the treatment of cisplatin-sensitive and cisplatin-resistant ovarian cancers...
  52. doi request reprint Clinical aspects of uterine papillary serous carcinoma
    Chad A Hamilton
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Walter Reed Army Medical Center, Washington, District of Columbia, USA
    Curr Opin Obstet Gynecol 20:26-33. 2008
    ..We review the demographic and clinicopathologic characteristics, and prognosis of women diagnosed with uterine papillary serous carcinoma, with a focus on clinical management...
  53. ncbi request reprint Mast cell density, angiogenesis, blood clotting, and prognosis in women with advanced ovarian cancer
    John K Chan
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Stanford University School of Medicine, 300 Pasteur Dr HH333, Stanford, CA 94305 5317, USA
    Gynecol Oncol 99:20-5. 2005
    ..To determine clinical or biological associations between mast cell density, blood clotting, angiogenesis, and survival of patients with advanced ovarian cancer...
  54. ncbi request reprint Clinicopathologic features of six cases of primary cervical lymphoma
    John K Chan
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Stanford Cancer Center, Stanford University School of Medicine, Stanford, CA, USA
    Am J Obstet Gynecol 193:866-72. 2005
    ..Primary lymphoma of the uterine cervix is rare, with less than 60 cases reported. We present a series of 6 patients with cervical lymphoma and review the literature...
  55. ncbi request reprint Innovations in fertility preservation for patients with gynecologic cancers
    Wen Shiung Liou
    Division of Gynecologic Oncology, Department of Gynecology and Obstetrics, Stanford University School of Medicine, Palo Alto, California, USA
    Fertil Steril 84:1561-73. 2005
    ..To review options for fertility preservation in women with gynecologic cancers...
  56. ncbi request reprint Juvenile granulosa cell tumor of the ovary associated with tuberous sclerosis
    Hongyan Guo
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Stanford University School of Medicine, 300 Pasteur Drive HH333, CA 94305, USA
    Gynecol Oncol 102:118-20. 2006
    ..Juvenile granulosa cell tumors of the ovary are rare neoplasms that typically occur in the first three decades of life and have excellent prognosis for early-staged disease...
  57. pmc Degranulating mast cells in fibrotic regions of human tumors and evidence that mast cell heparin interferes with the growth of tumor cells through a mechanism involving fibroblasts
    Michael Samoszuk
    Department of Pathology and Laboratory Medicine, University of California, Irvine, California, USA
    BMC Cancer 5:121. 2005
    ..The purpose of this study was to test the hypothesis that mast cells that are present in fibrotic regions of cancer can suppress the growth of tumor cells through an indirect mechanism involving peri-tumoral fibroblasts...
  58. ncbi request reprint A modified technique for insertion of intraperitoneal port for chemotherapy
    Wen Shiung Liou
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Stanford Cancer Center, Stanford University School of Medicine, Stanford, California 94305 5317, USA
    J Surg Oncol 90:247-8. 2005
    ..An effective method that provides a reliable access to the IP cavity is needed. In this report, we describe a novel technique of IP port placement that may prevent access problems and decrease patient discomfort...
  59. doi request reprint Prognostic factors and survival in 1396 patients with uterine leiomyosarcomas: emphasis on impact of lymphadenectomy and oophorectomy
    Daniel S Kapp
    Division of Radiation Therapy, Department of Radiation Oncology, Stanford University School of Medicine, Stanford Cancer Center, Stanford, California 94305 5847, USA
    Cancer 112:820-30. 2008
    ....
  60. ncbi request reprint Laparoscopic photodynamic diagnosis of ovarian cancer using 5-aminolevulinic acid in a rat model
    John K Chan
    Beckman Laser Institute, University of California Irvine, Irvine, CA 92612, USA
    Gynecol Oncol 87:64-70. 2002
    ..The objective of this study was to determine the efficacy and sensitivity of laparoscopic photodynamic diagnosis to detect 5-aminolevulinic acid (ALA)-induced fluorescent tumors in an animal model...
  61. ncbi request reprint Differences in prognostic molecular markers between women over and under 45 years of age with advanced ovarian cancer
    John K Chan
    Division of Obstetrics and Gynecology, Stanford University School of Medicine, California, USA
    Clin Cancer Res 10:8538-43. 2004
    ..The purpose of this study was to determine whether differences in molecular markers might explain the better prognosis of women < or =45 years of age versus women >45 years of age diagnosed with ovarian cancers...
  62. ncbi request reprint Outcomes of women with metachronous breast and ovarian carcinomas
    Wen Shiung Liou
    Department of Gynecology and Obstetrics, Stanford Cancer Center, Stanford University School of Medicine, 875 Blake Wilbur Drive, MC 5827, Stanford, CA 94305, USA
    Gynecol Oncol 103:190-4. 2006
    ..We proposed to determine the characteristics and outcomes of women diagnosed with metachronous breast and ovarian cancer...