C D Chambers

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Is genotype important in predicting the fetal alcohol syndrome?
    Christina D Chambers
    J Pediatr 141:751-2. 2002
  2. doi request reprint Time-dependent propensity score for assessing the effect of vaccine exposure on pregnancy outcomes through pregnancy exposure cohort studies
    Ronghui Xu
    Department of Family and Preventive Medicine, University of California, San Diego, 9500 Gilman Drive, MC 0112, La Jolla, CA 92093, USA
    Int J Environ Res Public Health 11:3074-85. 2014
  3. doi request reprint Risks and safety of pandemic H1N1 influenza vaccine in pregnancy: birth defects, spontaneous abortion, preterm delivery, and small for gestational age infants
    Christina D Chambers
    Department of Pediatrics, University of California San Diego, La Jolla, CA, United States Rady Children s Hospital, San Diego, CA, United States Department of Family and Preventive Medicine, University of California San Diego, La Jolla, CA, United States Clinical Translational Research Institute, University of California San Diego, La Jolla, CA, United States Vaccines and Medications in Pregnancy Surveillance System, United States Electronic address
    Vaccine 31:5026-32. 2013
  4. pmc Perceived neighborhood environment and physical activity in 11 countries: do associations differ by country?
    Ding Ding
    Department of Family Preventive Medicine, University of California San Diego, La Jolla, California, USA
    Int J Behav Nutr Phys Act 10:57. 2013
  5. doi request reprint Emerging data on the use of anti-tumor necrosis factor-alpha medications in pregnancy
    Christina D Chambers
    Department of Pediatrics, Division of Dysmorphology and Teratology, University of California San Diego, La Jolla, California, USA
    Birth Defects Res A Clin Mol Teratol 94:607-11. 2012
  6. pmc Birth outcomes in women who have taken leflunomide during pregnancy
    Christina D Chambers
    Rady Children s Hospital, University of California, San Diego, California 92093 0828, USA
    Arthritis Rheum 62:1494-503. 2010
  7. ncbi request reprint Drug safety in pregnant women and their babies: ignorance not bliss
    C D Chambers
    Department of Pediatrics, University of California, San Diego School of Medicine, La Jolla, California, USA
    Clin Pharmacol Ther 83:181-3. 2008
  8. ncbi request reprint Intrauterine growth restriction in like-sex twins discordant for structural defects
    Christina D Chambers
    Department of Pediatrics, Division of Dysmorphology and Teratology, University of California San Diego School of Medicine, La Jolla, 92103, USA
    Birth Defects Res A Clin Mol Teratol 76:246-8. 2006
  9. pmc Human pregnancy safety for agents used to treat rheumatoid arthritis: adequacy of available information and strategies for developing post-marketing data
    Christina D Chambers
    Department of Pediatrics, University of California, San Diego, CA, USA
    Arthritis Res Ther 8:215. 2006
  10. ncbi request reprint Alcohol consumption patterns among pregnant women in the Moscow region of the Russian Federation
    Christina D Chambers
    Department of Pediatrics, University of California at San Diego, La Jolla, CA, USA
    Alcohol 38:133-7. 2006

Research Grants

Collaborators

Detail Information

Publications44

  1. ncbi request reprint Is genotype important in predicting the fetal alcohol syndrome?
    Christina D Chambers
    J Pediatr 141:751-2. 2002
  2. doi request reprint Time-dependent propensity score for assessing the effect of vaccine exposure on pregnancy outcomes through pregnancy exposure cohort studies
    Ronghui Xu
    Department of Family and Preventive Medicine, University of California, San Diego, 9500 Gilman Drive, MC 0112, La Jolla, CA 92093, USA
    Int J Environ Res Public Health 11:3074-85. 2014
    ..The application of the Cox regression PS is illustrated using data from a recent study of the safety of pandemic H1N1 influenza vaccine during pregnancy. ..
  3. doi request reprint Risks and safety of pandemic H1N1 influenza vaccine in pregnancy: birth defects, spontaneous abortion, preterm delivery, and small for gestational age infants
    Christina D Chambers
    Department of Pediatrics, University of California San Diego, La Jolla, CA, United States Rady Children s Hospital, San Diego, CA, United States Department of Family and Preventive Medicine, University of California San Diego, La Jolla, CA, United States Clinical Translational Research Institute, University of California San Diego, La Jolla, CA, United States Vaccines and Medications in Pregnancy Surveillance System, United States Electronic address
    Vaccine 31:5026-32. 2013
    ..There is a need for additional information on the fetal risks and relative safety of the pandemic H1N1 monovalent or trivalent influenza (pH1N1)-containing vaccines in women exposed during pregnancy...
  4. pmc Perceived neighborhood environment and physical activity in 11 countries: do associations differ by country?
    Ding Ding
    Department of Family Preventive Medicine, University of California San Diego, La Jolla, California, USA
    Int J Behav Nutr Phys Act 10:57. 2013
    ..The current study examined whether associations between perceived attributes of neighborhood environments and physical activity differed by country...
  5. doi request reprint Emerging data on the use of anti-tumor necrosis factor-alpha medications in pregnancy
    Christina D Chambers
    Department of Pediatrics, Division of Dysmorphology and Teratology, University of California San Diego, La Jolla, California, USA
    Birth Defects Res A Clin Mol Teratol 94:607-11. 2012
    ..Currently ongoing controlled cohort studies for some of the TNF blocker medications will help to provide more definitive answers for clinicians and patients...
  6. pmc Birth outcomes in women who have taken leflunomide during pregnancy
    Christina D Chambers
    Rady Children s Hospital, University of California, San Diego, California 92093 0828, USA
    Arthritis Rheum 62:1494-503. 2010
    ..The present study was undertaken to investigate pregnancy outcomes in women who received leflunomide and were treated with cholestyramine during pregnancy...
  7. ncbi request reprint Drug safety in pregnant women and their babies: ignorance not bliss
    C D Chambers
    Department of Pediatrics, University of California, San Diego School of Medicine, La Jolla, California, USA
    Clin Pharmacol Ther 83:181-3. 2008
    ....
  8. ncbi request reprint Intrauterine growth restriction in like-sex twins discordant for structural defects
    Christina D Chambers
    Department of Pediatrics, Division of Dysmorphology and Teratology, University of California San Diego School of Medicine, La Jolla, 92103, USA
    Birth Defects Res A Clin Mol Teratol 76:246-8. 2006
    ....
  9. pmc Human pregnancy safety for agents used to treat rheumatoid arthritis: adequacy of available information and strategies for developing post-marketing data
    Christina D Chambers
    Department of Pediatrics, University of California, San Diego, CA, USA
    Arthritis Res Ther 8:215. 2006
    ..In addition, the strengths and weaknesses of post-marketing strategies for developing new pregnancy safety information are described...
  10. ncbi request reprint Alcohol consumption patterns among pregnant women in the Moscow region of the Russian Federation
    Christina D Chambers
    Department of Pediatrics, University of California at San Diego, La Jolla, CA, USA
    Alcohol 38:133-7. 2006
    ..These data indicate that pregnant women in these areas of the Moscow Region present an important opportunity for education and intervention for alcohol-related birth outcomes...
  11. ncbi request reprint Risks of hyperthermia associated with hot tub or spa use by pregnant women
    Christina D Chambers
    Department of Pediatrics, University of California, San Diego, La Jolla, California, USA
    Birth Defects Res A Clin Mol Teratol 76:569-73. 2006
    ..9 degrees C...
  12. ncbi request reprint Novel risk factor in gastroschisis: change of paternity
    Christina D Chambers
    Division of Dysmorphology and Teratology, Department of Pediatrics, University of California San Diego, La Jolla, CA 92103, USA
    Am J Med Genet A 143:653-9. 2007
    ..Further research is needed to corroborate these findings and to elucidate possible immunologic mechanisms involved in the pathogenesis of gastroschisis...
  13. doi request reprint Value of the small cohort study including a physical examination for minor structural defects in identifying new human teratogens
    Christina D Chambers
    Division of Dysmorphology and Teratology, Department of Pediatrics, School of Medicine, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0828, USA
    Congenit Anom (Kyoto) 51:16-20. 2011
    ....
  14. ncbi request reprint Selective serotonin-reuptake inhibitors and risk of persistent pulmonary hypertension of the newborn
    Christina D Chambers
    Department of Pediatrics, University of California, San Diego, La Jolla, CA 92103, USA
    N Engl J Med 354:579-87. 2006
    ..We performed a case-control study to assess whether PPHN is associated with exposure to SSRIs during late pregnancy...
  15. ncbi request reprint Weight gain in infants breastfed by mothers who take fluoxetine
    C D Chambers
    Departments of Pediatrics, University of California, San Diego, California 92103, USA
    Pediatrics 104:e61. 1999
    ..A secondary goal was to assess the frequency of reported side effects in infants who are breastfed by mothers who take fluoxetine...
  16. ncbi request reprint Postmarketing surveillance for human teratogenicity: a model approach
    C D Chambers
    Department of Pediatrics, University of California, San Diego, CA 92103 8446, USA
    Teratology 64:252-61. 2001
    ..The purpose of this report is to outline a complementary approach that can be used in addition to other more established methods to provide the most comprehensive evaluation of prenatal exposures with respect to teratogenicity...
  17. doi request reprint The role of teratology information services in screening for teratogenic exposures: challenges and opportunities
    Christina Chambers
    Department of Pediatrics, Division of Dysmorphology and Teratology, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA
    Am J Med Genet C Semin Med Genet 157:195-200. 2011
    ..A formal collaboration between the TIS cohort study model with a case-control study design is also underway and will provide complementary strengths...
  18. ncbi request reprint Selection bias in Teratology Information Service pregnancy outcome studies
    K A Johnson
    Department of Pediatrics, University of California San Diego, 200 W Arbor Drive, La Jolla, CA 92093, USA
    Teratology 64:79-82. 2001
    ..If these subjects tend to have different risk profiles than the population from which they are drawn, the results of TIS studies may have limited generalizability...
  19. pmc Can prenatal ultrasound detect the effects of in-utero alcohol exposure? A pilot study
    M Kfir
    Department of Reproductive Medicine, University of California San Diego, La Jolla, CA 92103 8433, USA
    Ultrasound Obstet Gynecol 33:683-9. 2009
    ..Early detection of fetuses at risk of FASD would support earlier interventions...
  20. doi request reprint Change in paternity and select perinatal outcomes: causal or confounded?
    G Bandoli
    Department of Pediatrics, University of California San Diego, San Diego, CA, USA
    J Obstet Gynaecol 32:657-62. 2012
    ..13; 4.47), after adjusting for selected risk factors. Paternity change remains a significant risk factor for pre-eclampsia and SGA in the presence of select risk factors...
  21. ncbi request reprint Postmarketing surveillance for drug safety in pregnancy: the Organization of Teratology Information Services project
    Robert J Felix
    California Teratogen Information Service and Clinical Research Program, Department of Pediatrics, University of California San Diego, La Jolla, CA 92103, USA
    Birth Defects Res A Clin Mol Teratol 70:944-7. 2004
    ..Although medications are frequently used during pregnancy, premarketing studies exclude pregnant women, with the result that maternal and fetal risks of medications are largely unknown prior to marketing...
  22. doi request reprint Potentially modifiable risk factors for adverse pregnancy outcomes in women with psoriasis
    G Bandoli
    Department of Pediatrics, University of California San Diego, La Jolla, CA, USA
    Br J Dermatol 163:334-9. 2010
    ..Data on pregnancy outcomes among women with psoriasis are lacking. However, there are several known comorbidities of psoriasis, including obesity, smoking and depression, each of which increases the risk for negative birth outcomes...
  23. pmc Developmental pathogenesis of short palpebral fissure length in children with fetal alcohol syndrome
    Kenneth Lyons Jones
    Department of Pediatrics, University of California, San Diego, La Jolla, California 92093 0828, USA
    Birth Defects Res A Clin Mol Teratol 85:695-9. 2009
    ..The purpose of this study was to examine whether short palpebral fissures are independent of or determined by the OFC...
  24. pmc Fetal alcohol spectrum disorders: Extending the range of structural defects
    Kenneth Lyons Jones
    Department of Pediatrics, University of California, San Diego, La Jolla, CA 92093 0828, USA
    Am J Med Genet A 152:2731-5. 2010
    ..Prenatal alcohol exposure may produce a broad spectrum of structural defects that goes beyond FAS with implications regarding the impact of alcohol on the developing fetus, a prerequisite for ultimate prevention of FASD...
  25. ncbi request reprint Pregnancy outcomes after first trimester exposure to phentermine/fenfluramine
    Kenneth Lyons Jones
    Department of Pediatrics, Division of Dysmorphology and Teratology, University of California San Diego, La Jolla, CA 92093, USA
    Teratology 65:125-30. 2002
    ..The possible effect on the developing fetus has not been studied...
  26. ncbi request reprint Minor malformations characteristic of the retinoic acid embryopathy and other birth outcomes in children of women exposed to topical tretinoin during early pregnancy
    Kirsten D Loureiro
    Graduate School of Public Health, San Diego State University, CA 92103, USA
    Am J Med Genet A 136:117-21. 2005
    ..Although it is impossible to exclude the possibility that some women/infants may be uniquely susceptible to topical tretinoin exposure, this study provides further reassurance for women who are inadvertently exposed early in pregnancy...
  27. ncbi request reprint Safety of leukotriene receptor antagonists in pregnancy
    Ludmila N Bakhireva
    Department of Pediatrics, University of California, San Diego, La Jolla, CA 92093, USA
    J Allergy Clin Immunol 119:618-25. 2007
    ..Asthma is a chronic disorder that affects about 8% of pregnant women and may complicate pregnancy. Adequate asthma therapy in pregnancy is crucial but challenging because of safety concerns for the fetus...
  28. ncbi request reprint Accuracy of the diagnosis of physical features of fetal alcohol syndrome by pediatricians after specialized training
    Kenneth Lyons Jones
    Department of Pediatrics, Division of Dysmorphology and Teratology, University of California San Diego, La Jolla, California, USA
    Pediatrics 118:e1734-8. 2006
    ..After a structured training program for pediatricians, we examined the ability to accurately diagnose fetal alcohol syndrome...
  29. ncbi request reprint Effect of maternal asthma and gestational asthma therapy on fetal growth
    Ludmila N Bakhireva
    Department of Pediatrics, University of California La Jolla, San Diego, California 92103, USA
    J Asthma 44:71-6. 2007
    ..Methodological and practical considerations related to safety of asthma medications in pregnancy and management of gestational asthma are discussed...
  30. ncbi request reprint Monitoring leflunomide (Arava) as a new potential teratogen
    Kenneth Lyons Jones
    Department of Pediatrics, Division of Dysmorphology and Teratology, University of California, San Diego, La Jolla 92093, USA
    Teratology 65:200-2. 2002
  31. ncbi request reprint Alcohol consumption among low-income pregnant Latinas
    Christina D Chambers
    Department of Pediatrics and Family and Preventive Medicine, University of California, San Diego, La Jolla, CA, USA
    Alcohol Clin Exp Res 29:2022-8. 2005
    ..We assessed the prevalence of alcohol consumption in a sample of low-income pregnant Latinas and examined risk factors for alcohol use in the periconceptional period...
  32. ncbi request reprint Risk for fetal death after fever in pregnancy
    Christina D Chambers
    Division of Dysmorphology Teratology, Department of Pediatrics, University of California, San Diego, School of Medicine, La Jolla, CA 92103, USA
    Lancet 360:1526. 2002
  33. ncbi request reprint Alcohol use in pregnancy: inadequate recommendations for an increasing problem
    K L Jones
    Division of Dysmorphology and Teratology, Department of Pediatrics, University of California, San Diego, La Jolla, CA 92037 0811, USA
    BJOG 113:967-8. 2006
  34. ncbi request reprint Asthma medication use in pregnancy and fetal growth
    Ludmila N Bakhireva
    Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA
    J Allergy Clin Immunol 116:503-9. 2005
    ..Given the high prevalence of asthma in pregnancy, it is important to understand the relationship between asthma medications and fetal growth in the context of appropriate treatment...
  35. ncbi request reprint Interaction of maternal smoking and other in-pregnancy exposures: analytic considerations
    Sarah N Mattson
    Center for Behavioral Teratology, Department of Psychology, San Diego State University, San Diego, CA, USA
    Neurotoxicol Teratol 24:359-67. 2002
    ....
  36. doi request reprint Inconsistent report of pre-pregnancy-recognition alcohol use by Latinas
    Suzanne C Hughes
    Center for Behavioral Epidemiology and Community Health, San Diego State University, 9245 Sky Park Court, Suite 230, San Diego, CA 92123, USA
    Matern Child Health J 13:857-64. 2009
    ..This study compared pregnant Latinas' report of alcohol use for the 3-month period before pregnancy recognition with two different methods of data collection, in an attempt to identify opportunities for improved screening...
  37. ncbi request reprint Prevalence of periconceptional folic acid use and perceived barriers to the postgestation continuance of supplemental folic acid: survey results from a Teratogen Information Service
    Beck B Goldberg
    Graduate School of Public Health, San Diego State University, San Diego, California 92103, USA
    Birth Defects Res A Clin Mol Teratol 76:193-9. 2006
    ..A better understanding of the vitamin-taking habits of childbearing-age women and effective methods for improving periconceptional supplement use are needed...
  38. ncbi request reprint Neurodevelopmental follow-up of children of women infected with varicella during pregnancy: a prospective study
    Sarah N Mattson
    Center for Behavioral Teratology, Department of Psychology, San Diego State University, 6363 Alvarado Court, Suite 209, San Diego, CA 92120, USA
    Pediatr Infect Dis J 22:819-23. 2003
    ..However, the incidence of neurobehavioral deficits in asymptomatic structurally normal children whose mothers had clinically diagnosed varicella-zoster virus infection is unknown...
  39. pmc The plausibility of maternal nutritional status being a contributing factor to the risk for fetal alcohol spectrum disorders: the potential influence of zinc status as an example
    Carl L Keen
    Department of Nutrition, University of California, Davis, Davis, CA 95616, USA
    Biofactors 36:125-35. 2010
    ....
  40. ncbi request reprint Evidence-based assessment of pregnancy outcome after sumatriptan exposure
    Anthony W Fox
    EBD Group, Carlsbad, Calif 92009, USA
    Headache 42:8-15. 2002
    ..Assessment of best available evidence for tolerability of sumatriptan after inadvertent exposure during pregnancy...
  41. doi request reprint Fetal sex and maternal asthma control in pregnancy
    Ludmila N Bakhireva
    Division of Pharmacy Practice and Department of Family Community Medicine, University of New Mexico, Albuquerque, New Mexico, USA
    J Asthma 45:403-7. 2008
    ..84; 95% CI: 1.05; 3.21) independent of maternal age, BMI, ethnicity, smoking, and socioeconomic status. The current study suggests that pregnant asthmatic women carrying a girl might be more susceptible to asthma exacerbations...
  42. doi request reprint Asthma control during pregnancy and the risk of preterm delivery or impaired fetal growth
    Ludmila N Bakhireva
    Division of Pharmacy Practice and Department of Family Community Medicine, University of New Mexico, Albuquerque, New Mexico 87131 0001, USA
    Ann Allergy Asthma Immunol 101:137-43. 2008
    ..Concerns regarding potential harmful effect of medications on fetuses often result in inadequate treatment of asthma in pregnancy, whereas risks posed by poorly controlled maternal asthma are often underestimated...
  43. ncbi request reprint Communicating risks during pregnancy: a workshop on the use of data from animal developmental toxicity studies in pregnancy labels for drugs
    Anthony R Scialli
    Department of Obstetrics and Gynecology, Georgetown University Medical Center, 3800 Reservoir Road NW, Washington, DC 20007 2119, USA
    Birth Defects Res A Clin Mol Teratol 70:7-12. 2004
  44. ncbi request reprint Statement of the Public Affairs Committee of the Teratology Society on the fetal alcohol syndrome
    Jane Adams
    Department of Psychology, University of Massachusetts, Boston, Massachusetts 02125 3393, USA
    Teratology 66:344-7. 2002

Research Grants2