Research Topics
| C D ChambersSummaryAffiliation: University of California Country: USA Publications
Research Grants
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Detail Information
Publications
Is genotype important in predicting the fetal alcohol syndrome?Christina D Chambers
J Pediatr 141:751-2. 2002
Emerging data on the use of anti-tumor necrosis factor-alpha medications in pregnancyChristina D Chambers
Department of Pediatrics, Division of Dysmorphology and Teratology, University of California San Diego, La Jolla, California, USA
Birth Defects Res A Clin Mol Teratol 94:607-11. 2012..Currently ongoing controlled cohort studies for some of the TNF blocker medications will help to provide more definitive answers for clinicians and patients...- Weight gain in infants breastfed by mothers who take fluoxetineC D Chambers
Departments of Pediatrics, University of California, San Diego, California 92103, USA
Pediatrics 104:e61. 1999..A secondary goal was to assess the frequency of reported side effects in infants who are breastfed by mothers who take fluoxetine... - Risks of hyperthermia associated with hot tub or spa use by pregnant womenChristina D Chambers
Department of Pediatrics, University of California, San Diego, La Jolla, California, USA
Birth Defects Res A Clin Mol Teratol 76:569-73. 2006..9 degrees C... - Intrauterine growth restriction in like-sex twins discordant for structural defectsChristina D Chambers
Department of Pediatrics, Division of Dysmorphology and Teratology, University of California San Diego School of Medicine, La Jolla, 92103, USA
Birth Defects Res A Clin Mol Teratol 76:246-8. 2006.... - Selective serotonin-reuptake inhibitors and risk of persistent pulmonary hypertension of the newbornChristina D Chambers
Department of Pediatrics, University of California, San Diego, La Jolla, CA 92103, USA
N Engl J Med 354:579-87. 2006..We performed a case-control study to assess whether PPHN is associated with exposure to SSRIs during late pregnancy... 
Human pregnancy safety for agents used to treat rheumatoid arthritis: adequacy of available information and strategies for developing post-marketing dataChristina D Chambers
Department of Pediatrics, University of California, San Diego, CA, USA
Arthritis Res Ther 8:215. 2006..In addition, the strengths and weaknesses of post-marketing strategies for developing new pregnancy safety information are described...- Novel risk factor in gastroschisis: change of paternityChristina D Chambers
Division of Dysmorphology and Teratology, Department of Pediatrics, University of California San Diego, La Jolla, CA 92103, USA
Am J Med Genet A 143:653-9. 2007..Further research is needed to corroborate these findings and to elucidate possible immunologic mechanisms involved in the pathogenesis of gastroschisis... - Drug safety in pregnant women and their babies: ignorance not blissC D Chambers
Department of Pediatrics, University of California, San Diego School of Medicine, La Jolla, California, USA
Clin Pharmacol Ther 83:181-3. 2008.... - Alcohol consumption patterns among pregnant women in the Moscow region of the Russian FederationChristina D Chambers
Department of Pediatrics, University of California at San Diego, La Jolla, CA, USA
Alcohol 38:133-7. 2006..These data indicate that pregnant women in these areas of the Moscow Region present an important opportunity for education and intervention for alcohol-related birth outcomes... - Birth outcomes in women who have taken leflunomide during pregnancyChristina D Chambers
Rady Children s Hospital, University of California, San Diego, California 92093 0828, USA
Arthritis Rheum 62:1494-503. 2010..The present study was undertaken to investigate pregnancy outcomes in women who received leflunomide and were treated with cholestyramine during pregnancy... - Value of the small cohort study including a physical examination for minor structural defects in identifying new human teratogensChristina D Chambers
Division of Dysmorphology and Teratology, Department of Pediatrics, School of Medicine, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0828, USA
Congenit Anom (Kyoto) 51:16-20. 2011.... - Postmarketing surveillance for human teratogenicity: a model approachC D Chambers
Department of Pediatrics, University of California, San Diego, CA 92103 8446, USA
Teratology 64:252-61. 2001..The purpose of this report is to outline a complementary approach that can be used in addition to other more established methods to provide the most comprehensive evaluation of prenatal exposures with respect to teratogenicity... - The role of teratology information services in screening for teratogenic exposures: challenges and opportunitiesChristina Chambers
Department of Pediatrics, Division of Dysmorphology and Teratology, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA
Am J Med Genet C Semin Med Genet 157:195-200. 2011..A formal collaboration between the TIS cohort study model with a case-control study design is also underway and will provide complementary strengths... - Selection bias in Teratology Information Service pregnancy outcome studiesK A Johnson
Department of Pediatrics, University of California San Diego, 200 W Arbor Drive, La Jolla, CA 92093, USA
Teratology 64:79-82. 2001..If these subjects tend to have different risk profiles than the population from which they are drawn, the results of TIS studies may have limited generalizability... - Can prenatal ultrasound detect the effects of in-utero alcohol exposure? A pilot studyM Kfir
Department of Reproductive Medicine, University of California San Diego, La Jolla, CA 92103 8433, USA
Ultrasound Obstet Gynecol 33:683-9. 2009..Early detection of fetuses at risk of FASD would support earlier interventions... - Postmarketing surveillance for drug safety in pregnancy: the Organization of Teratology Information Services projectRobert J Felix
California Teratogen Information Service and Clinical Research Program, Department of Pediatrics, University of California San Diego, La Jolla, CA 92103, USA
Birth Defects Res A Clin Mol Teratol 70:944-7. 2004.... - Change in paternity and select perinatal outcomes: causal or confounded?G Bandoli
Department of Pediatrics, University of California San Diego, San Diego, CA, USA
J Obstet Gynaecol 32:657-62. 2012..13; 4.47), after adjusting for selected risk factors. Paternity change remains a significant risk factor for pre-eclampsia and SGA in the presence of select risk factors... - Potentially modifiable risk factors for adverse pregnancy outcomes in women with psoriasisG Bandoli
Department of Pediatrics, University of California San Diego, La Jolla, CA, USA
Br J Dermatol 163:334-9. 2010..Data on pregnancy outcomes among women with psoriasis are lacking. However, there are several known comorbidities of psoriasis, including obesity, smoking and depression, each of which increases the risk for negative birth outcomes... - Accuracy of the diagnosis of physical features of fetal alcohol syndrome by pediatricians after specialized trainingKenneth Lyons Jones
Department of Pediatrics, Division of Dysmorphology and Teratology, University of California San Diego, La Jolla, California, USA
Pediatrics 118:e1734-8. 2006..After a structured training program for pediatricians, we examined the ability to accurately diagnose fetal alcohol syndrome... - Fetal alcohol spectrum disorders: Extending the range of structural defectsKenneth Lyons Jones
Department of Pediatrics, University of California, San Diego, La Jolla, CA 92093 0828, USA
Am J Med Genet A 152:2731-5. 2010..Prenatal alcohol exposure may produce a broad spectrum of structural defects that goes beyond FAS with implications regarding the impact of alcohol on the developing fetus, a prerequisite for ultimate prevention of FASD... - Developmental pathogenesis of short palpebral fissure length in children with fetal alcohol syndromeKenneth Lyons Jones
Department of Pediatrics, University of California, San Diego, La Jolla, California 92093 0828, USA
Birth Defects Res A Clin Mol Teratol 85:695-9. 2009..The purpose of this study was to examine whether short palpebral fissures are independent of or determined by the OFC... - Safety of leukotriene receptor antagonists in pregnancyLudmila N Bakhireva
Department of Pediatrics, University of California, San Diego, La Jolla, CA 92093, USA
J Allergy Clin Immunol 119:618-25. 2007..Asthma is a chronic disorder that affects about 8% of pregnant women and may complicate pregnancy. Adequate asthma therapy in pregnancy is crucial but challenging because of safety concerns for the fetus... - Pregnancy outcomes after first trimester exposure to phentermine/fenfluramineKenneth Lyons Jones
Department of Pediatrics, Division of Dysmorphology and Teratology, University of California San Diego, La Jolla, CA 92093, USA
Teratology 65:125-30. 2002..The possible effect on the developing fetus has not been studied... - Minor malformations characteristic of the retinoic acid embryopathy and other birth outcomes in children of women exposed to topical tretinoin during early pregnancyKirsten D Loureiro
Graduate School of Public Health, San Diego State University, CA 92103, USA
Am J Med Genet A 136:117-21. 2005..Although it is impossible to exclude the possibility that some women/infants may be uniquely susceptible to topical tretinoin exposure, this study provides further reassurance for women who are inadvertently exposed early in pregnancy... - Risk for fetal death after fever in pregnancyChristina D Chambers
Division of Dysmorphology/Teratology, Department of Pediatrics, University of California, San Diego, School of Medicine, La Jolla, CA 92103, USA
Lancet 360:1526. 2002 - Monitoring leflunomide (Arava) as a new potential teratogenKenneth Lyons Jones
Department of Pediatrics, Division of Dysmorphology and Teratology, University of California, San Diego, La Jolla 92093, USA
Teratology 65:200-2. 2002 - Effect of maternal asthma and gestational asthma therapy on fetal growthLudmila N Bakhireva
Department of Pediatrics, University of California La Jolla, San Diego, California 92103, USA
J Asthma 44:71-6. 2007..Methodological and practical considerations related to safety of asthma medications in pregnancy and management of gestational asthma are discussed... - Alcohol consumption among low-income pregnant LatinasChristina D Chambers
Department of Pediatrics and Family and Preventive Medicine, University of California, San Diego, La Jolla, CA, USA
Alcohol Clin Exp Res 29:2022-8. 2005..Selective interventions in low-income Latinas are warranted, and should be focused on women of reproductive age who are binge or frequent drinkers and who are at risk of becoming pregnant... - Alcohol use in pregnancy: inadequate recommendations for an increasing problemK L Jones
Division of Dysmorphology and Teratology, Department of Pediatrics, University of California, San Diego, La Jolla, CA 92037-0811, USA
BJOG 113:967-8. 2006 - Asthma medication use in pregnancy and fetal growthLudmila N Bakhireva
Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA
J Allergy Clin Immunol 116:503-9. 2005.... - Interaction of maternal smoking and other in-pregnancy exposures: analytic considerationsSarah N Mattson
Center for Behavioral Teratology, Department of Psychology, San Diego State University, San Diego, CA, USA
Neurotoxicol Teratol 24:359-67. 2002.... - Neurodevelopmental follow-up of children of women infected with varicella during pregnancy: a prospective studySarah N Mattson
Center for Behavioral Teratology, Department of Psychology, San Diego State University, 6363 Alvarado Court, Suite 209, San Diego, CA 92120, USA
Pediatr Infect Dis J 22:819-23. 2003..However, the incidence of neurobehavioral deficits in asymptomatic structurally normal children whose mothers had clinically diagnosed varicella-zoster virus infection is unknown... - Inconsistent report of pre-pregnancy-recognition alcohol use by LatinasSuzanne C Hughes
Center for Behavioral Epidemiology and Community Health, San Diego State University, 9245 Sky Park Court, Suite 230, San Diego, CA 92123, USA
Matern Child Health J 13:857-64. 2009..This study compared pregnant Latinas' report of alcohol use for the 3-month period before pregnancy recognition with two different methods of data collection, in an attempt to identify opportunities for improved screening... - Prevalence of periconceptional folic acid use and perceived barriers to the postgestation continuance of supplemental folic acid: survey results from a Teratogen Information ServiceBeck B Goldberg
Graduate School of Public Health, San Diego State University, San Diego, California 92103, USA
Birth Defects Res A Clin Mol Teratol 76:193-9. 2006..This represents an opportunity for TIS specialists and physicians to intervene in a current pregnancy to encourage maintenance of supplement use in the subsequent interpregnancy interval... - The plausibility of maternal nutritional status being a contributing factor to the risk for fetal alcohol spectrum disorders: the potential influence of zinc status as an exampleCarl L Keen
Department of Nutrition, University of California, Davis, Davis, CA 95616, USA
Biofactors 36:125-35. 2010.... - Asthma control during pregnancy and the risk of preterm delivery or impaired fetal growthLudmila N Bakhireva
Division of Pharmacy Practice and Department of Family Community Medicine, University of New Mexico, Albuquerque, New Mexico 87131 0001, USA
Ann Allergy Asthma Immunol 101:137-43. 2008..Concerns regarding potential harmful effect of medications on fetuses often result in inadequate treatment of asthma in pregnancy, whereas risks posed by poorly controlled maternal asthma are often underestimated... - Fetal sex and maternal asthma control in pregnancyLudmila N Bakhireva
Division of Pharmacy Practice and Department of Family Community Medicine, University of New Mexico, Albuquerque, New Mexico, USA
J Asthma 45:403-7. 2008..84; 95% CI: 1.05; 3.21) independent of maternal age, BMI, ethnicity, smoking, and socioeconomic status. The current study suggests that pregnant asthmatic women carrying a girl might be more susceptible to asthma exacerbations... - Evidence-based assessment of pregnancy outcome after sumatriptan exposureAnthony W Fox
EBD Group, Carlsbad, Calif 92009, USA
Headache 42:8-15. 2002..Patients inadvertently exposed to sumatriptan during an early stage of pregnancy should be reassured by these data... - Statement of the Public Affairs Committee of the Teratology Society on the fetal alcohol syndromeJane Adams
Department of Psychology, University of Massachusetts, Boston, Massachusetts 02125-3393, USA
Teratology 66:344-7. 2002 - Communicating risks during pregnancy: a workshop on the use of data from animal developmental toxicity studies in pregnancy labels for drugsAnthony R Scialli
Department of Obstetrics and Gynecology, Georgetown University Medical Center, 3800 Reservoir Road NW, Washington, DC 20007-2119, USA
Birth Defects Res A Clin Mol Teratol 70:7-12. 2004
Research Grants
- Spectrum of and Nutritional Risk Factors for FASD in Russia and UkraineChristina Chambers; Fiscal Year: 2007....