Affiliation: University of California
- CompMoby: comparative MobyDick for detection of cis-regulatory motifsChristina Chaivorapol
Department of Biochemistry and Biophysics, California Institute for Quantitative Biomedical Research, Graduate Program in Biological and Medical Informatics, University of California, San Francisco, CA 94143 2540, USA
BMC Bioinformatics 9:455. 2008..Therefore, a computational algorithm should account for both conserved and nonconserved cis-regulatory elements in metazoans...
- fREDUCE: detection of degenerate regulatory elements using correlation with expressionRandy Z Wu
Department of Biochemistry and Biophysics, UCSF, 1700 4th Street, San Francisco, CA 94143 2542, USA
BMC Bioinformatics 8:399. 2007..A major challenge is to decipher transcription factor binding sites from sequence and functional genomic data using computational means. While current methods can detect strong binding sites, they are less sensitive to degenerate motifs...
- Cell- and gene-specific regulation of primary target genes by the androgen receptorEric C Bolton
Department of Cellular and Molecular Pharmacology, University of California, San Francisco, California 94143, USA
Genes Dev 21:2005-17. 2007..Our results provide new insights into cell- and gene-specific mechanisms of transcriptional regulation of androgen-responsive gene networks...