Research Topics
| Anees B ChagparSummaryAffiliation: University of Louisville Country: USA Publications
Research Grants
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Publications
Predicting patients at low probability of requiring postmastectomy radiation therapyAnees B Chagpar
Division of Surgical Oncology, University of Louisville, 315 East Broadway, Suite 312, Louisville, KY 40202, USA
Ann Surg Oncol 14:670-7. 2007..Given the ramifications of PMRT for immediate reconstruction, we sought to create a model using preoperative and intraoperative factors to predict which patients with a positive sentinel lymph node will have less than four LN+...
Clinical significance of minimal sentinel node involvement and management optionsAnees B Chagpar
Department of Surgery, University of Louisville, 315 East Broadway, Suite 312, Louisville, KY 40202, USA
Surg Oncol Clin N Am 19:493-505. 2010..The relevance of such minute disease has been controversial, and there has been considerable debate as to how best to manage such patients...- Determinants of early distant metastatic disease in elderly patients with breast cancerAnees B Chagpar
Division of Surgical Oncology, Department of Surgery, University of Louisville, 315 E Broadway, Suite 312, Louisville, KY 40202, USA
Am J Surg 192:317-21. 2006..The purpose of this analysis was to determine predictors of early distant metastasis in elderly breast cancer patients receiving hormonal therapy... - Treatment of sentinel node-positive breast cancerAnees B Chagpar
Division of Surgical Oncology Director, JG Brown Cancer Center Multidisciplinary Breast Program, University of Louisville, 312 East Broadway, Suite 314, Louisville, KY 40202, USA
Expert Rev Anticancer Ther 6:1233-9. 2006..This review addresses the controversies regarding the management of sentinel node-positive breast cancer patients... - Prediction of sentinel lymph node-only disease in women with invasive breast cancerAnees B Chagpar
Department of Surgery, University of Louisville, 315 East Broadway, Suite 312, Louisville, KY 40202, USA
Am J Surg 192:882-7. 2006..The purpose of this study was to create a model that predicts which breast cancer patients will have sentinel lymph node (SLN)-only metastasis... - Trends in mammography and clinical breast examination: a population-based studyAnees B Chagpar
Division of Surgical Oncology, Department of Surgery, University of Louisville, Louisville, Kentucky 40202, USA
J Surg Res 140:214-9. 2007..The purpose of this study was to determine trends in the utilization of these techniques over the past 5 years... - Factors determining adequacy of axillary node dissection in breast cancer patientsAnees B Chagpar
Departments of Surgery, University of Louisville, Lousiville, KY 40202, USA
Breast J 13:233-7. 2007..Surgeons with a more breast experience had a lower rate of adequate ALND. Patient age, surgeon academic affiliation, and breast experience, as well as community size are all significant factors predictive of adequacy of ALND... - Extramammary Paget's disease of the axilla: an unusual caseAnees B Chagpar
Department of Surgery, University of Louisville, Louisville, Kentucky, USA
Breast J 13:291-3. 2007..We present a case of extramammary Paget's disease of the axilla, and discuss the known literature regarding this rare disease... - Are 3 sentinel nodes sufficient?Anees B Chagpar
Department of Surgery, University of Louisville, Louisville, KY, USA
Arch Surg 142:456-9; discussion 459-60. 2007..Our objective was to determine the false-negative rate (FNR) associated with limiting SLN biopsy to 3 nodes... - Factors influencing the number of sentinel lymph nodes identified in patients with breast cancerAnees B Chagpar
Division of Surgical Oncology, Department of Surgery, University of Louisville, 315 East Broadway, Suite 312, Louisville, KY, USA
Am J Surg 194:860-4; discussion 864-5. 2007..Few SLNs are required for adequate staging; removal of more may be unnecessary. The objective of this study was to determine factors influencing the number of SLN identified... - The use of radiation therapy after breast-conserving surgery in hormonally treated breast cancer patients is dependent on patient age, geographic region, and surgeon specialtyAnees B Chagpar
Department of Surgery, University of Louisville, Louisville, KY, USA
Am J Surg 195:793-8. 2008..The use of radiation therapy (RT) after breast-conserving surgery (BCS) is inconsistent in patients treated with hormonal therapy (HT). We sought to identify factors influencing the decision to use RT in this setting... - Racial trends in mammography rates: a population-based studyAnees B Chagpar
Division of Surgical Oncology, Department of Surgery, University of Louisville, Louisville, KY, USA
Surgery 144:467-72. 2008..The rates of mammography have been declining over the last 5 years. The objective of this study was to examine racial disparities in this trend... - Can sentinel node biopsy be avoided in some elderly breast cancer patients?Anees B Chagpar
Division of Surgical Oncology, Department of Surgery, University of Louisville, Louisville, Kentucky, USA
Ann Surg 249:455-60. 2009.... - Does ductal carcinoma in situ accompanying invasive carcinoma affect prognosis?Anees B Chagpar
Department of Surgery, University of Louisville, Louisville, KY, USA
Surgery 146:561-7; discussion 567-8. 2009..Ductal carcinoma in situ (DCIS) often accompanies invasive breast cancer. The prognostic implication of this is unclear. We sought to determine whether concomitant DCIS affects outcomes in patients with invasive disease... - Factors associated with surgical options for breast carcinomaAnees B Chagpar
Division of Surgical Oncology, Department of Surgery, University of Louisville, KY, USA
Cancer 106:1462-6. 2006..The current study evaluated the impact of patient and physician factors on surgical decision-making... - Sentinel lymph node biopsy for breast cancer: from investigational procedure to standard practiceAnees B Chagpar
Division of Surgical Oncology, University of Louisville, KY 40202, USA
Expert Rev Anticancer Ther 4:903-12. 2004..The historic roots of this technique are discussed, along with the controversial issues surrounding the technique and the clinical trials that are currently ongoing... - Validation of subareolar and periareolar injection techniques for breast sentinel lymph node biopsyAnees Chagpar
Department of Surgery, Division of Surgical Oncology, University of Louisville, Louisville, KY, USA
Arch Surg 139:614-8; discussion 618-20. 2004..Subareolar or periareolar injection of radioactive technetium sulfur colloid is equivalent to other injection techniques for breast cancer sentinel lymph node (SLN) biopsy... - Factors predicting failure to identify a sentinel lymph node in breast cancerAnees B Chagpar
Division of Surgical Oncology, Department of Surgery, University of Louisville, KY, USA
Surgery 138:56-63. 2005..The purpose of this study was to elucidate factors that independently predict failure to identify an SLN... - Biopsy type does not influence sentinel lymph node statusAnees B Chagpar
Department of Surgery, University of Louisville, 315 E Broadway, Suite 312, Louisville, KY 40202, USA
Am J Surg 190:551-6. 2005..This study sought to determine whether the type of biopsy examination independently affects sentinel lymph node (SLN) status in breast cancer patients... - Effect of lymphoscintigraphy drainage patterns on sentinel lymph node biopsy in patients with breast cancerAnees B Chagpar
Department of Surgery, University of Louisville, 315 E Broadway, Suite 312, Louisville, KY 40202, USA
Am J Surg 190:557-62. 2005..Sentinel lymph node (SLN) biopsy examination is an accepted method of staging breast cancer patients. SLN biopsy examination in patients with drainage to the internal mammary chain (IMC) nodes is controversial... - Advances in the management of localized breast cancer: an overviewAnees B Chagpar
Division of Surgical Oncology, Department of Surgery, University of Louisville School of Medicine, Center for Advanced Surgical Technologies, Louisville, KY 40292, USA
J Ky Med Assoc 102:202-8. 2004..As we enter the new millennium, breast cancer management will continue to evolve... - The replication error phenotype is associated with the development of distant metastases in hormonally treated patients with breast carcinomaAnees Chagpar
Department of Surgery, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
Cancer 100:913-9. 2004..More recently, this phenotype also has been described in breast carcinoma... - Surgeon and community factors affecting breast cancer sentinel lymph node biopsyJulie R Hutchinson
Division of Surgical Oncology, Department of Surgery, University of Louisville, Louisville, KY 40292, USA
Am J Surg 190:903-6. 2005..79, P = .0073) was surgeon experience (>20 SLN cases). CONCLUSIONS: Surgeon experience is the major factor that contributes to improved SLN biopsy results. SLN biopsy can be performed equally well by community and academic surgeons... - Body mass index influences palpability but not stage of breast cancer at diagnosisAnees B Chagpar
Department of Surgery, University of Louisville, Louisville, Kentucky, USA
Am Surg 73:555-60; discussion 560. 2007..9 vs > or =30). Increased BMI does not lead to a worse stage at presentation. Obese patients, however, tend to have nonpalpable tumors. Mammography in this population is especially important... - Effect of multiple-nodal basin drainage on cutaneous melanomaAndrea C Federico
Division of Surgical Oncology, Department of Surgery, University of Louisville School of Medicine, Louisville, KY 40292
Arch Surg 143:632-7; discussion 637-8. 2008..The number of nodal basins draining a primary cutaneous melanoma is not an independent predictor of outcome... - Lymph node ratio: a proposed refinement of current axillary staging in breast cancer patientsSuzanne C Schiffman
Department of Surgery, University of Louisville, Louisville, KY, USA
J Am Coll Surg 213:45-52; discussion 52-3. 2011..The optimal method for classifying lymph node (LN) status in breast cancer patients is unknown. We sought to determine if LN ratio (LNR) improves axillary staging... - Should sentinel lymph-node biopsy be used routinely for staging melanoma and breast cancers?Charles R Scoggins
Department of Surgery, University of Louisville, Louisville, KY 40202, USA
Nat Clin Pract Oncol 2:448-55. 2005..The objectives of this review are to provide a current and concise overview of the current literature on SLN biopsy and describe its role in clinical oncology... - The role of sentinel node biopsy in women undergoing prophylactic mastectomySamiha M Nasser
Department of Surgery, University of Louisville, Louisville, Kentucky, USA
J Surg Res 164:188-92. 2010..We sought to determine the incidence of finding occult cancer and the frequency of SLN positivity in patients undergoing contralateral PM... - Primary tumor size, not race, determines outcomes in women with hormone-responsive breast cancerAnees B Chagpar
Department of Surgery, Yale University, New Haven, CT 06510, USA
Surgery 150:796-801. 2011..We sought to determine if there was a difference in outcomes in African-American compared with Caucasian women with hormone-responsive breast cancer, and whether this was related to race or other tumor and treatment variables... - Lymph node ratio should be considered for incorporation into staging for breast cancerAnees B Chagpar
Department of Surgery, Yale University School of Medicine, New Haven, CT, USA
Ann Surg Oncol 18:3143-8. 2011..We sought to determine whether lymph node ratio (LNR; defined as number of positive nodes/number of nodes dissected) provides additional prognostic information in node-positive breast cancer patients... - Lumpectomy margins are affected by tumor size and histologic subtype but not by biopsy techniqueAnees B Chagpar
Department of Surgery, University of Louisville, 315 E. Broadway, Suite #312, Louisville, KY 40202, USA
Am J Surg 188:399-402. 2004..The type of biopsy, needle or excisional, had no effect on the ability to achieve negative margins... 
Gender-related differences in outcome for melanoma patientsCharles R Scoggins
Division of Surgical Oncology, Department of Surgery, University of Louisville, KY 40292, USA
Ann Surg 243:693-8; discussion 698-700. 2006..0001). CONCLUSIONS: Male gender is associated with a greater incidence of unfavorable primary tumor characteristics without an increased risk for nodal metastasis. Nonetheless, gender is an independent factor affecting survival...- The lower incidence of melanoma in women may be related to increased preventative behaviorsNathaniel P Reuter
Department of Surgery, CentraCare Clinic, St Cloud, MN, USA
Am J Surg 200:765-8, discussion 768-9. 2010..Men have a higher lifetime incidence of melanoma than women... - A strategic approach to the evaluation of axillary lymph nodes in breast cancer patients: analysis of 168 patients at a single institutionSunati Sahoo
Department of Pathology, University Louisville Hospital, University of Louisville, 530 South Jackson St, Louisville, KY 40202, USA
Am J Surg 194:524-6. 2007..The purpose of this study was to examine and determine the number of operative procedures that could be excluded using both approaches... - The surgical management of breast cancerBeatrix A Slomiany
Department of Surgery, Division of Surgical Oncology, University of Louisville, Louisville, KY 40202, USA
J Ky Med Assoc 107:391-5. 2009.... - The impact of lymphovascular invasion on lymph node status in patients with breast cancerLaura B Cornwell
Department of Surgery, University of Louisville, Louisville, Kentucky, USA
Am Surg 77:874-7. 2011..002). Although LVI is known to be associated with lymph node status, it is not frequently noted on pathology reports. Given its prognostic value, LVI should be carefully evaluated and reported... - The recent decline in mammography rates is limited to low- to average-risk womenBeatrix A Slomiany
Department of Surgery, Division of Surgical Oncology, University of Louisville, 315 E Broadway, Suite 312, Louisville, KY 40202, USA
Am J Surg 196:821-6; discussion 826. 2008..There has recently been a decline in mammography rates noted in the general population. We sought to determine whether similar trends hold in high-risk populations... - Pathologic evaluation of cryoprobe-assisted lumpectomy for breast cancerSunati Sahoo
Departments of Pathology, University of Louisville Hospital, Louisville, KY 40202, USA
Am J Clin Pathol 128:239-44. 2007..The "cryoprobe effect" did not interfere with evaluation of the margins and surrounding breast tissue... - Breast biopsy marker masquerading as a mass lesionHouda Alatassi
Department of Pathology, University of Louisville Hospital, Louisville, Kentucky 40241, USA
Breast J 11:504-5. 2005 - Adherence to physical activity guidelines in breast cancer survivorsSavanna G Smith
From the Department of Surgery, University of Louisville, Louisville, Kentucky, USA
Am Surg 76:962-5. 2010..73; 95% CI: 0.41-1.30, P = 0.282). Despite more interaction with healthcare providers, breast cancer survivors are no more likely to adhere to activity guidelines than the general population... - Malignant phylloides tumor in pregnancyKristen M Blaker
Department of Surgery, University of Louisville, Louisville, Kentucky, USA
Am Surg 76:302-5. 2010..With early detection, malignant phylloides tumors can present in the first trimester of pregnancy at smaller sizes; in these patients, breast-conserving surgery is possible... - Skin-sparing and nipple-sparing mastectomy: preoperative, intraoperative, and postoperative considerationsAnees B Chagpar
Division of Surgical Oncology, University of Louisville, Louisville, Kentucky, USA
Am Surg 70:425-32. 2004..In addition, newer techniques, which spare the nipple and/or areola, warrant further examination... - Clinicopathologic factors associated with false-negative sentinel lymph-node biopsy in breast cancerRobert C G Martin
Department of Surgery, Division of Surgical Oncology, University of Louisville, Louisville, Kentucky 40202, USA
Ann Surg 241:1005-12; discussion 1012-5. 2005.... - Novel intraoperative molecular test for sentinel lymph node metastases in patients with early-stage breast cancerThomas B Julian
Allegheny Breast Care Center, Allegheny General Hospital, 320 E North Ave, Pittsburgh, PA 15212, USA
J Clin Oncol 26:3338-45. 2008..We present the results from a large, prospective evaluation of the first rapid molecular SLN test, the Breast Lymph Node (BLN) Assay... - Predicting extensive nodal disease in women with breast cancerAnees B Chagpar
Ann Surg Oncol 13:3-4. 2006 - Accuracy of physical examination, ultrasonography, and mammography in predicting residual pathologic tumor size in patients treated with neoadjuvant chemotherapyAnees B Chagpar
Department of Surgical Oncology, University of Texas M.D. Anderson Cancer Center, Houston, TX 77030-4095, USA
Ann Surg 243:257-64. 2006..CONCLUSION: Physical examination, ultrasonography, and mammography were only moderately useful for predicting residual pathologic tumor size after neoadjuvant chemotherapy... - Insights into the management of locally advanced, inflammatory, and metastatic breast cancer: highlights from the 2007 Louisville Breast Cancer UpdateAnees B Chagpar
J Ky Med Assoc 105:559-60. 2007
Research Grants
- Louisville Breast Cancer UpdateAnees Chagpar; Fiscal Year: 2007..This annual event is the only one of its kind in Kentucky, and provides an important resource for education of clinicians, scientists and advocates. ..