Matteo Cesari

Summary

Affiliation: University of Florida
Country: USA

Publications

  1. ncbi request reprint Anemia and cognitive performance in hospitalized older patients: results from the GIFA study
    Valentina Zamboni
    Department of Gerontology, Geriatrics and Physiatry, Catholic University of Sacred Heart, Rome, Italy
    Int J Geriatr Psychiatry 21:529-34. 2006
  2. pmc Frailty syndrome and skeletal muscle: results from the Invecchiare in Chianti study
    Matteo Cesari
    Department of Aging and Geriatric Research, College of Medicine, Institute on Aging, University of Florida, Gainesville, FL 32608, USA
    Am J Clin Nutr 83:1142-8. 2006
  3. ncbi request reprint Oxidative damage and platelet activation as new predictors of mobility disability and mortality in elders
    Matteo Cesari
    Department of Aging and Geriatric Research, College of Medicine, Institute on Aging, University of Florida, Gainesville, Florida 36208, USA
    Antioxid Redox Signal 8:609-19. 2006
  4. ncbi request reprint Comorbidity and physical function: results from the aging and longevity study in the Sirente geographic area (ilSIRENTE study)
    Matteo Cesari
    Department of Gerontology, Geriatrics and Physiatry, Catholic University of Sacred Heart, Rome, Italy
    Gerontology 52:24-32. 2006
  5. ncbi request reprint Lipoprotein peroxidation and mobility limitation: results from the Health, Aging, and Body Composition Study
    Matteo Cesari
    Department of Aging and Geriatric Research, College of Medicine, Institute on Aging, University of Florida, Gainesville 32608, USA
    Arch Intern Med 165:2148-54. 2005
  6. ncbi request reprint Prognostic value of usual gait speed in well-functioning older people--results from the Health, Aging and Body Composition Study
    Matteo Cesari
    Department of Aging and Geriatric Research, College of Medicine, Institute on Aging, University of Florida, Gainesville, Florida 32608, USA
    J Am Geriatr Soc 53:1675-80. 2005
  7. ncbi request reprint Sarcopenia, obesity, and inflammation--results from the Trial of Angiotensin Converting Enzyme Inhibition and Novel Cardiovascular Risk Factors study
    Matteo Cesari
    Department of Aging and Geriatric Research, College of Medicine, Institute on Aging, University of Florida, Gainesville, FL, USA
    Am J Clin Nutr 82:428-34. 2005
  8. ncbi request reprint Target population for clinical trials on sarcopenia
    M Cesari
    Department of Aging and Geriatric Research, University of Florida Institute on Aging, Gainesville, FL 32611, USA
    J Nutr Health Aging 12:470-8. 2008
  9. pmc Skeletal muscle and mortality results from the InCHIANTI Study
    Matteo Cesari
    Department of Gerontology, Geriatrics, and Physiatry, Catholic University of Sacred Heart, Rome, Italy
    J Gerontol A Biol Sci Med Sci 64:377-84. 2009
  10. ncbi request reprint Depression and physical function: results from the aging and longevity study in the Sirente geographic area (ilSIRENTE Study)
    Andrea Russo
    Department of Gerontology, Geriatrics and Physiatry, Catholic University of Sacred Heart, Roma, Italy
    J Geriatr Psychiatry Neurol 20:131-7. 2007

Research Grants

Detail Information

Publications85

  1. ncbi request reprint Anemia and cognitive performance in hospitalized older patients: results from the GIFA study
    Valentina Zamboni
    Department of Gerontology, Geriatrics and Physiatry, Catholic University of Sacred Heart, Rome, Italy
    Int J Geriatr Psychiatry 21:529-34. 2006
    ..Anemia represents a major risk factor for adverse health-related events in older persons. The aim of this study was to evaluate the association between hemoglobin levels/anemia and cognitive function in hospitalized older persons...
  2. pmc Frailty syndrome and skeletal muscle: results from the Invecchiare in Chianti study
    Matteo Cesari
    Department of Aging and Geriatric Research, College of Medicine, Institute on Aging, University of Florida, Gainesville, FL 32608, USA
    Am J Clin Nutr 83:1142-8. 2006
    ..Frailty is a common condition in elders and identifies a state of vulnerability for adverse health outcomes...
  3. ncbi request reprint Oxidative damage and platelet activation as new predictors of mobility disability and mortality in elders
    Matteo Cesari
    Department of Aging and Geriatric Research, College of Medicine, Institute on Aging, University of Florida, Gainesville, Florida 36208, USA
    Antioxid Redox Signal 8:609-19. 2006
    ..g., physical activity, dietary restriction, smoking cessation) play an important role in the reduction of oxidative damage levels and are associated with improved physical performance and muscle strength...
  4. ncbi request reprint Comorbidity and physical function: results from the aging and longevity study in the Sirente geographic area (ilSIRENTE study)
    Matteo Cesari
    Department of Gerontology, Geriatrics and Physiatry, Catholic University of Sacred Heart, Rome, Italy
    Gerontology 52:24-32. 2006
    ..Physical function measures have gained increased importance in the evaluation of older persons. The presence of comorbidity is a major and growing issue in geriatrics...
  5. ncbi request reprint Lipoprotein peroxidation and mobility limitation: results from the Health, Aging, and Body Composition Study
    Matteo Cesari
    Department of Aging and Geriatric Research, College of Medicine, Institute on Aging, University of Florida, Gainesville 32608, USA
    Arch Intern Med 165:2148-54. 2005
    ..The aim of this study was to assess the predictive value of a lipoprotein peroxidation marker, oxidized low-density lipoprotein (oxLDL) for incident mobility limitation (ML)...
  6. ncbi request reprint Prognostic value of usual gait speed in well-functioning older people--results from the Health, Aging and Body Composition Study
    Matteo Cesari
    Department of Aging and Geriatric Research, College of Medicine, Institute on Aging, University of Florida, Gainesville, Florida 32608, USA
    J Am Geriatr Soc 53:1675-80. 2005
    ..To define clinically relevant cutpoints for usual gait speed and to investigate their predictive value for health-related events in older persons...
  7. ncbi request reprint Sarcopenia, obesity, and inflammation--results from the Trial of Angiotensin Converting Enzyme Inhibition and Novel Cardiovascular Risk Factors study
    Matteo Cesari
    Department of Aging and Geriatric Research, College of Medicine, Institute on Aging, University of Florida, Gainesville, FL, USA
    Am J Clin Nutr 82:428-34. 2005
    ..Age-related body-composition changes are associated with health-related outcomes in elders. This relation may be explained by inflammation and hemostatic abnormalities...
  8. ncbi request reprint Target population for clinical trials on sarcopenia
    M Cesari
    Department of Aging and Geriatric Research, University of Florida Institute on Aging, Gainesville, FL 32611, USA
    J Nutr Health Aging 12:470-8. 2008
    ..The development of clinical trials exploring the nature of the sarcopenia process is urgent, but several controversial issues on this hallmark of aging still need clarification...
  9. pmc Skeletal muscle and mortality results from the InCHIANTI Study
    Matteo Cesari
    Department of Gerontology, Geriatrics, and Physiatry, Catholic University of Sacred Heart, Rome, Italy
    J Gerontol A Biol Sci Med Sci 64:377-84. 2009
    ..Sarcopenia, the age-related loss of muscle mass, may not be an isolated process but is associated with an increase in fat mass. The aim of this study was to estimate the mortality risk of sarcopenia in the presence or absence of obesity...
  10. ncbi request reprint Depression and physical function: results from the aging and longevity study in the Sirente geographic area (ilSIRENTE Study)
    Andrea Russo
    Department of Gerontology, Geriatrics and Physiatry, Catholic University of Sacred Heart, Roma, Italy
    J Geriatr Psychiatry Neurol 20:131-7. 2007
    ..In conclusion, physical performance and functional status measures are significantly and negatively influenced by the presence of depression in community-dwelling older persons aged 80 years and older...
  11. ncbi request reprint Physical activity prevented functional decline among frail community-living elderly subjects in an international observational study
    Francesco Landi
    Department of Gerontology Geriatric, Catholic University Sacred Heart, Rome, Italy
    J Clin Epidemiol 60:518-24. 2007
    ..The aims of the study were to describe the prevalence of physical activity in a sample of older adults in home care in Europe and to examine the relationship between physical activity and incident disability...
  12. ncbi request reprint The ilSIRENTE study: a prospective cohort study on persons aged 80 years and older living in a mountain community of Central Italy
    Francesco Landi
    Department of Gerontology, Geriatric and Physiatric, Catholic University of Sacred Heart, Rome, Italy
    Aging Clin Exp Res 17:486-93. 2005
    ....
  13. doi request reprint Walking one hour or more per day prevented mortality among older persons: results from ilSIRENTE study
    Francesco Landi
    Department of Gerontology, Geriatrics and Physiatry, Catholic University of Sacred Heart, Roma, Italy
    Prev Med 47:422-6. 2008
    ..The aim of the present study was to explore the relationship between regular walking and the risk of all-cause death in a large population of frail and very old people living in community...
  14. ncbi request reprint Psychotropic medications and risk for falls among community-dwelling frail older people: an observational study
    Francesco Landi
    Department of Gerontology Geriatrics, Catholic University of Sacred Heart, Rome, Italy
    J Gerontol A Biol Sci Med Sci 60:622-6. 2005
    ..Although a small number of falls have a single cause, the majority have many different causes resulting from the interactions between intrinsic or extrinsic risk factors...
  15. ncbi request reprint The effects of cognitive impairment on mortality among hospitalized patients with heart failure
    Giuseppe Zuccala
    Department of Gerontology, Catholic University of the Sacred Heart, Rome, Italy
    Am J Med 115:97-103. 2003
    ..Because cerebral metabolic abnormalities have been associated with reduced survival in younger patients with advanced heart failure, we assessed the effect of cognitive impairment on the survival of older patients with heart failure...
  16. ncbi request reprint Indwelling urethral catheter and mortality in frail elderly women living in community
    Francesco Landi
    Department of Gerontology Geriatric and Physiatric, Catholic University of Sacred Heart, Rome, Italy
    Neurourol Urodyn 23:697-701. 2004
    ..The aims of present study were to describe the prevalence of bladder catheter in a population of older women living in community and to examine the relationship between urinary catheter and mortality...
  17. ncbi request reprint Impact of inflammation on the relationship among alcohol consumption, mortality, and cardiac events: the health, aging, and body composition study
    Cinzia Maraldi
    Department of Aging and Geriatric Research, College of Medicine, Institute on Aging, University of Florida, 1329 SW 16th St, Gainesville, FL 32608, USA
    Arch Intern Med 166:1490-7. 2006
    ..We investigated the relationship of alcohol intake with all-cause mortality and cardiac events and evaluated whether this relationship is mediated or modified by inflammatory markers...
  18. ncbi request reprint Anemia and recovery from disability in activities of daily living in hospitalized older persons
    Cinzia Maraldi
    Department of Aging and Geriatric Research, College of Medicine, Institute on Aging, University of Florida, Gainesville, FL 32608, USA
    J Am Geriatr Soc 54:632-6. 2006
    ..To evaluate the predictive value of hemoglobin levels upon hospital admission on recovery from activity of daily living (ADL) disability during hospital stay in older patients...
  19. ncbi request reprint Comorbidity and social factors predicted hospitalization in frail elderly patients
    Francesco Landi
    Instituto di Medicina Interna e Geriatria, Centro Medicina dell Invecchiamento, Universita Cattolica del Sacro Cuore, Rome, Italy
    J Clin Epidemiol 57:832-6. 2004
    ....
  20. ncbi request reprint In a prospective observational study, influenza vaccination prevented hospitalization among older home care patients
    Francesco Landi
    Department of Gerontology Geriatric and Physiatric, Catholic University of Sacred Heart, 00168 Rome, Italy
    J Clin Epidemiol 59:1072-7. 2006
    ..The aim of the study is (1) to describe the prevalence of vaccination against influenza in older home care patients and (2) to investigate the protective effect of influenza vaccination for hospitalization events...
  21. pmc Added value of physical performance measures in predicting adverse health-related events: results from the Health, Aging And Body Composition Study
    Matteo Cesari
    Department of Aging and Geriatric Reseach, Institute on Aging, University of Florida, Gainesville, 32611, USA
    J Am Geriatr Soc 57:251-9. 2009
    ..To determine how three different physical performance measures (PPMs) combine for added utility in predicting adverse health events in elders...
  22. pmc Interaction of HDL cholesterol concentrations on the relationship between physical function and inflammation in community-dwelling older persons
    Matteo Cesari
    Centro per la Salute dell Anziano Area di Geriatria, Università Campus Bio Medico, Rome, Italy
    Age Ageing 39:74-80. 2010
    ..the existence of a relationship among inflammation, high-density lipoprotein cholesterol (HDL-C) and physical function has been suggested...
  23. pmc Self-assessed health status, walking speed and mortality in older Mexican-Americans
    Matteo Cesari
    Department of Aging and Geriatric Research, University of Florida Institute on Aging, Gainesville, FL 32611, USA
    Gerontology 55:194-201. 2009
    ..Nevertheless, the possible interaction between them in predicting major outcomes has not been clearly explored...
  24. ncbi request reprint Insulin-like growth factor-binding protein 3 and hemoglobin concentration in older persons living in the community
    Francesco Landi
    Department of Gerontology and Geriatrics, Catholic University of Sacred Heart, Roma, Italy
    Int J Hematol 85:294-9. 2007
    ..This finding suggests that the growth hormone/IGF axis may play an important role in hematopoiesis, and it may be implicated in the age-related decline in hemoglobin concentration...
  25. pmc Angiotensin-converting enzyme inhibitor use by older adults is associated with greater functional responses to exercise
    Thomas W Buford
    Department of Aging and Geriatric Research, University of Florida College of Medicine, Gainesville, Florida 32607, USA
    J Am Geriatr Soc 60:1244-52. 2012
    ..To assess the association between angiotensin converting enzyme inhibitors (ACEis) and improvements in the physical function of older adults in response to chronic exercise training...
  26. ncbi request reprint Physical function and perceived quality of life in older persons
    Oriana Fusco
    Department of Gerontology, Geriatrics, and Physical Medicine, Catholic University of the Sacred Heart, Rome, Italy
    Aging Clin Exp Res 24:68-73. 2012
    ..The aim of the study was to verify which specific physical function measure is a more important predictor of quality of life in these individuals...
  27. ncbi request reprint Anemia, physical disability, and survival in older patients with heart failure
    Cinzia Maraldi
    Department of Aging and Geriatric Research, College of Medicine, Institute on Aging, University of Florida, Gainesville, Florida 32608, USA
    J Card Fail 12:533-9. 2006
    ..The effect of anemia on functional ability in heart failure has not been described. We evaluated the relationship of anemia, physical disability, and survival in patients with heart failure...
  28. ncbi request reprint HDL-cholesterol and physical performance: results from the ageing and longevity study in the sirente geographic area (ilSIRENTE Study)
    Francesco Landi
    Department of Gerontology, Geriatrics and Physiatry, Catholic University of Sacred Heart, Roma, Italy
    Age Ageing 36:514-20. 2007
    ..We evaluate the relationship of HDL-cholesterol with measures of physical performance, muscle strength, and functional status in older persons aged 80years or older...
  29. ncbi request reprint Free insulin-like growth factor-I and cognitive function in older persons living in community
    Francesco Landi
    Department of Gerontology and Geriatrics, Catholic University of Sacred Heart, 00168, Roma, Italy
    Growth Horm IGF Res 17:58-66. 2007
    ..Increasing evidences from experimental and human studies suggest that the activity of the growth hormone (GH/insulin-like growth factor-I) axis may contribute to the age-related cognitive decline and poor cognition in late life...
  30. ncbi request reprint Association between daily pain and physical function among old-old adults living in the community: results from the ilSIRENTE study
    Graziano Onder
    Department of Gerontology, Catholic University of Sacred Heart, Rome, Italy
    Pain 121:53-9. 2006
    ..In conclusion, the present study shows that among old-old subjects living in the community, daily pain is highly prevalent and that this condition is associated with impaired muscle strength and physical performance...
  31. ncbi request reprint Physical activity and risk of cognitive impairment among older persons living in the community
    Francesco Landi
    Department of Gerontology and Geriatrics, Catholic University of the Sacred Heart, Rome, Italy
    Aging Clin Exp Res 19:410-6. 2007
    ..The aim of the present study was to evaluate the relationship of lifetime physical activity with cognitive performance in older persons aged 80 years or older...
  32. ncbi request reprint Use of ACE inhibitors is associated with elevated levels of IGFBP-3 among hypertensive older adults: results from the IlSIRENTE study
    Graziano Onder
    Department of Geriatrics, Catholic University of the Sacred Heart, Rome, Italy
    Eur J Clin Pharmacol 63:389-95. 2007
    ..However, this relationship has only rarely been investigated in humans. The aim of the present cross-sectional study was to assess the association of ACE inhibitors with free IGF-1 and IGFBP-3 in the blood of older hypertensive adults...
  33. ncbi request reprint Serum high-density lipoprotein cholesterol levels and mortality in frail, community-living elderly
    Francesco Landi
    Department of Gerontology and Geriatrics, Catholic University of Sacred Heart, Rome, Italy
    Gerontology 54:71-8. 2008
    ..High-density lipoprotein (HDL) cholesterol has been hypothesized to be a reliable marker of frailty and poor prognosis among the oldest elderly...
  34. doi request reprint Angiotensin-converting enzyme inhibition and novel cardiovascular risk biomarkers: results from the Trial of Angiotensin Converting Enzyme Inhibition and Novel Cardiovascular Risk Factors (TRAIN) study
    Matteo Cesari
    Department of Aging and Geriatric Research, University of Florida Institute on Aging, Gainesville, 32611, USA
    Am Heart J 157:334.e1-8. 2009
    ..The present study evaluates effects of an ACE inhibitor (ie, fosinopril) intervention on novel cardiovascular risk factors...
  35. ncbi request reprint Use of angiotensin-converting enzyme inhibitors and variations in cognitive performance among patients with heart failure
    Giuseppe Zuccala
    Catholic University, Department of Gerontology, Geriatrics, and Physiatrics, L go F Vito, I 00168 Rome, Italy
    Eur Heart J 26:226-33. 2005
    ..Our aim was to assess whether starting treatment with ACE-inhibitors might improve cognition in patients with heart failure...
  36. ncbi request reprint Diabetes mellitus, glycemic control, and incident depressive symptoms among 70- to 79-year-old persons: the health, aging, and body composition study
    Cinzia Maraldi
    Institute on Aging, University of Florida, USA
    Arch Intern Med 167:1137-44. 2007
    ..The causal mechanisms and temporal sequence of this association have not been clearly delineated. This study investigated the prospective relationship between DM and depressive symptoms...
  37. ncbi request reprint Body mass index, free insulin-like growth factor I, and physical function among older adults: results from the ilSIRENTE study
    Graziano Onder
    Department of Geriatrics, Catholic University of Sacred Heart, Rome, Italy
    Am J Physiol Endocrinol Metab 291:E829-34. 2006
    ..By contrast, no association was observed between IGFBP-3 and study outcomes, independently of BMI. In conclusion, high IGF-I level is associated with better physical function in older persons with obesity, but not in nonobese subjects...
  38. pmc ACE-inhibition and physical function: results from the Trial of Angiotensin-Converting Enzyme Inhibition and Novel Cardiovascular Risk Factors (TRAIN) study
    Matteo Cesari
    Centro per la Salute dell Anziano Area di Geriatria, Università Campus Bio Medico, Via Alvaro del Portillo 5, Rome, Italy
    J Am Med Dir Assoc 11:26-32. 2010
    ..Aim of the present study was to evaluate whether an ACE inhibitor intervention is able to significantly improve physical performance and muscle strength in a sample of older persons...
  39. pmc Plasminogen activator inhibitor-1 (PAI-1): a key factor linking fibrinolysis and age-related subclinical and clinical conditions
    Matteo Cesari
    Area di Geriatria, Università Campus Bio Medico, Rome, Italy
    Cardiovasc Ther 28:e72-91. 2010
    ..The plasminogen activator system plays a key role in a wide range of physiological and pathological processes...
  40. ncbi request reprint Physical exercise and comorbidity. Results from the Fitness and Arthritis in Seniors Trial (FAST)
    Irene Mangani
    Department of Aging and Geriatric Research, College of Medicine, Institute on Aging, University of Florida, Gainesville, FL, USA
    Aging Clin Exp Res 18:374-80. 2006
    ..The impact of comorbidity on the benefits from physical exercise has not been clearly investigated. Elders with comorbidity may benefit from physical exercise to preserve physical function...
  41. ncbi request reprint Anemia is associated with depression in older adults: results from the InCHIANTI study
    Graziano Onder
    Geriatric Department, Catholic University of the Sacred Heart, Rome, Italy
    J Gerontol A Biol Sci Med Sci 60:1168-72. 2005
    ..The objective of this study was to examine whether depressive symptoms and anemia are associated among older adults living in the community...
  42. ncbi request reprint Physical activity and mortality in frail, community-living elderly patients
    Francesco Landi
    Department of Gerontology, Geriatrics and Physiatrics, Catholic University of the Sacred Heart, Rome, Italy
    J Gerontol A Biol Sci Med Sci 59:833-7. 2004
    ..The authors describe the prevalence of moderate-intensity physical activity in a population of older persons living in the community. In addition, they explore the relationship between physical activity and mortality...
  43. ncbi request reprint Effects of influenza vaccination on mortality among frail, community-living elderly patients: an observational study
    Francesco Landi
    Department of Gerontology, Geriatric and Physiatric Medicine, Catholic University of the Sacred Heart, Roma, Italy
    Aging Clin Exp Res 15:254-8. 2003
    ..The aims of the present study were to describe the prevalence of vaccination against influenza in a population of older people living in the community, and to examine the relationship between influenza vaccination and mortality...
  44. pmc Effects of antioxidant supplementation on the aging process
    Domenico Fusco
    Department of Gerontology, Geriatrics and Physiatry, Catholic University of Sacred Heart, Rome, Italy
    Clin Interv Aging 2:377-87. 2007
    ..The aim of this paper is to provide the main basis from which future studies should start and indicate which the main limitations that need to be addressed are...
  45. ncbi request reprint Potentially reversible risk factors and urinary incontinence in frail older people living in community
    Francesco Landi
    Institute of Internal Medicine, Department of Gerontology Geriatric and Physiatric, Catholic University of Sacred Heart, Largo Agostino Gemelli 8, I 00168 Rome, Italy
    Age Ageing 32:194-9. 2003
    ..However, few data exist concerning the potentially reversible causes of this condition among frail community-dwelling older individuals...
  46. ncbi request reprint Prevalence and risk factors for falls in an older community-dwelling population
    Matteo Cesari
    Department of Gerontology, Geriatrics, and Physiatric Sciences, Catholic University of the Sacred Heart, Rome, Italy
    J Gerontol A Biol Sci Med Sci 57:M722-6. 2002
    ..The aim of this study was to determine the prevalence of falls and related intrinsic and extrinsic risk factors in a community-dwelling older population...
  47. ncbi request reprint Predictors of rehabilitation outcomes in frail patients treated in a geriatric hospital
    Francesco Landi
    Department of Gerontology and Geriatrics, Catholic University of Sacred Heart, Rome, Italy
    J Am Geriatr Soc 50:679-84. 2002
    ..To evaluate the effect of medical indicators of health status on functional gain during rehabilitation of frail older patients...
  48. ncbi request reprint Pain and its relation to depressive symptoms in frail older people living in the community: an observational study
    Francesco Landi
    Istituto di Medicina Interna e Geriatria, Universita Cattolica del Sacro Cuore, Rome, Italy
    J Pain Symptom Manage 29:255-62. 2005
    ..Treatment models that put together the assessment and the treatment of both pain and depression are indispensable for better outcomes...
  49. ncbi request reprint Use of calcium antagonists and worsening renal function in patients receiving angiotensin-converting-enzyme inhibitors
    Giuseppe Zuccala
    Catholic University of the Sacred Heart, L go F Vito 1, 00168, Rome, Italy
    Eur J Clin Pharmacol 58:695-9. 2003
    ....
  50. pmc The aging process and potential interventions to extend life expectancy
    Matteo Tosato
    Department of Gerontology, Geriatrics and Physiatry, Catholic University of Sacred Heart, Rome, Italy
    Clin Interv Aging 2:401-12. 2007
    ..The present review provides an overlook of the most commonly accepted theories of aging, providing current evidence of those interventions aimed at modifying the aging process...
  51. ncbi request reprint Non-steroidal anti-inflammatory drug (NSAID) use and Alzheimer disease in community-dwelling elderly patients
    Francesco Landi
    Department of Gerontology Geriatric and Physiatric, Catholic University of the Sacred Heart, Rome, Italy
    Am J Geriatr Psychiatry 11:179-85. 2003
    ..The aim of the present study was to examine the relationship between NSAIDs use and AD in a large sample of community-dwelling elderly people...
  52. ncbi request reprint Effects of an occupational therapy program on functional outcomes in older stroke patients
    Francesco Landi
    Department of Gerontology Geriatric and Physiatric, Catholic University of Sacred Heart, Rome, Italy
    Gerontology 52:85-91. 2006
    ..Objective: To evaluate the efficacy of occupational therapy programs in patients with a recent stroke...
  53. pmc Effects of a weight loss plus exercise program on physical function in overweight, older women: a randomized controlled trial
    Stephen D Anton
    Department of Aging and Geriatric Research, University of Florida, Gainesville, USA
    Clin Interv Aging 6:141-9. 2011
    ..This study tested whether a weight loss program combined with moderate exercise could improve physical function in obese, older adult women...
  54. ncbi request reprint Benzodiazepines and the risk of urinary incontinence in frail older persons living in the community
    Francesco Landi
    Department of Gerontology Geriatrics and Physiatrics, Catholic University of Sacred Heart, Rome, Italy
    Clin Pharmacol Ther 72:729-34. 2002
    ..The aim of this study was to estimate the risk of urinary incontinence associated with the use of oxidative or nonoxidative benzodiazepines...
  55. ncbi request reprint Topical treatment of pressure ulcers with nerve growth factor: a randomized clinical trial
    Francesco Landi
    Department of Geriatrics, Catholic University of the Sacred Heart, Rome, Italy
    Ann Intern Med 139:635-41. 2003
    ..Management options for pressure ulcers include local wound care; surgical repair; and, more recently, topical application of growth factors...
  56. doi request reprint Onco-geriatric approach for the management of older patients with cancer
    Matteo Cesari
    Università Campus Bio Medico, Rome, Italy
    J Am Med Dir Assoc 12:153-9. 2011
    ..In fact, aggressive antineoplastic managements are often denied to older patients, possibly because of the common misconception suggesting older age and/or clinical complexity as absolute contraindications to advanced treatments...
  57. doi request reprint Gas exchanges and pulmonary vascular abnormalities at different stages of chronic liver disease
    Simone Scarlata
    Unit of Respiratory Pathophysiology, Universita Campus BioMedico, Rome, Italy
    Liver Int 31:525-33. 2011
    ..Aim of this study was to compare pulmonary capillary volumes and gas exchange efficiency of CLD patients with and without cirrhosis...
  58. ncbi request reprint Adverse drug reactions and cognitive function among hospitalized older adults
    Graziano Onder
    Centro Medicina dell Invecchiamento, Universita Cattolica del Sacro Cuore, Rome, Italy
    Eur J Clin Pharmacol 58:371-7. 2002
    ..To explore the relationship between cognitive function and the detection of adverse drug reactions (ADRs) and to evaluate whether cognitive function could influence the association between age and ADRs...
  59. doi request reprint Vitamin D hormone: a multitude of actions potentially influencing the physical function decline in older persons
    Matteo Cesari
    Geriatric Medicine Unit, Campus Bio Medico University, Rome, Italy
    Geriatr Gerontol Int 11:133-42. 2011
    ..Special focus is given to skeletal muscle and physical function. Limitations of available scientific evidence on the topic are also discussed...
  60. doi request reprint Spontaneous resolution of a giant pulmonary bulla in an older woman: role of functional assessment
    Simone Scarlata
    Centro per la Salute dell Anziano Area di Geriatria, Università Campus Bio Medico, Rome, Italy
    Respiration 81:59-62. 2011
    ..Interestingly, the reported case is characterized by a negligible improvement in respiratory function parameters, despite a substantial increase in the 6-min walking test and the oxygen arteriolar partial pressure...
  61. ncbi request reprint Impact of hospitalization on blood pressure control in Italy: results from the Italian Group of Pharmacoepidemiology in the Elderly (GIFA)
    Graziano Onder
    Section of Gerontology and Geriatrics, Stricht Center on Aging, Wake Forest University Baptist Medical Center, Winston Salem, North Carolina 27157, USA
    Pharmacotherapy 23:240-7. 2003
    ..To evaluate whether hospitalization affects blood pressure control in hypertensive patients, and to identify factors associated with attainment of adequate blood pressure control and with aggressive pharmacologic treatment...
  62. ncbi request reprint Antioxidants and physical performance in elderly persons: the Invecchiare in Chianti (InCHIANTI) study
    Matteo Cesari
    Sticht Center on Aging, Wake Forest University Health Sciences, Winston Salem, NC 27157, USA
    Am J Clin Nutr 79:289-94. 2004
    ..Muscle strength and physical performance in old age might be related to the oxidative damage caused by free radicals...
  63. ncbi request reprint Moderate alcohol consumption and adverse drug reactions among older adults
    Graziano Onder
    Section of Gerontology and Geriatrics, Sticht Center on Aging, Wake Forest University, Baptist Medical Center, Winston Salem, NC, USA
    Pharmacoepidemiol Drug Saf 11:385-92. 2002
    ..To assess the effect of moderate alcohol consumption on Adverse Drug Reactions (ADRs) among older adults admitted to acute care hospitals and to examine the consistency of this effect across gender and age groups...
  64. ncbi request reprint Inflammatory markers and cardiovascular health in older adults
    Stephen B Kritchevsky
    Sticht Center on Aging, Section of Gerontology and Geriatric Medicine, Department of Internal Medicine, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157, USA
    Cardiovasc Res 66:265-75. 2005
    ..Thus it is possible that, in older age-groups, interventions designed to prevent cardiovascular disease through the modulation of inflammation would also be helpful in reducing disability and mortality...
  65. ncbi request reprint Inappropriate medication use among hospitalized older adults in Italy: results from the Italian Group of Pharmacoepidemiology in the Elderly
    Graziano Onder
    Centro Medicina dell Invecchiamento, Universita Cattolica del Sacro Cuore, Policlinico A Gemelli, L go Francesco Vito 1, 00168, Roma, Italy
    Eur J Clin Pharmacol 59:157-62. 2003
    ..To determine the prevalence of inappropriate medication use among hospitalized older adults and to identify predictors of this use...
  66. ncbi request reprint Inflammatory markers and cardiovascular disease (The Health, Aging and Body Composition [Health ABC] Study)
    Matteo Cesari
    Sticht Center on Aging, Wake Forest University Health Sciences, Winston Salem, North Carolina 27157, USA
    Am J Cardiol 92:522-8. 2003
    ..Thus, our findings suggest an important role for IL-6 and TNF-alpha in clinical as well as subclinical cardiovascular disease. In this study, CRP had a weaker association with cardiovascular disease than the cytokines...
  67. ncbi request reprint Abdominal obesity is an independent risk factor for chronic heart failure in older people
    Barbara J Nicklas
    Sticht Center on Aging, Section on Gerontology and Geriatric Medicine, Department of Internal Medicine, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    J Am Geriatr Soc 54:413-20. 2006
    ..To examine whether total and abdominal adiposity are risk factors for the development of chronic heart failure (CHF) in older men and women...
  68. ncbi request reprint Correlates of cognitive impairment among patients with heart failure: results of a multicenter survey
    Giuseppe Zuccala
    Catholic University of the Sacred Heart, Largo F Vito, I 00168 Rome, Italy
    Am J Med 118:496-502. 2005
    ..We assessed the correlates of cognitive impairment among patients with heart failure enrolled in a multicenter pharmacoepidemiology survey...
  69. ncbi request reprint Association of visceral adipose tissue with incident myocardial infarction in older men and women: the Health, Aging and Body Composition Study
    Barbara J Nicklas
    Section on Gerontology and Geriatric Medicine, Sticht Center on Aging, Wake Forest University School of Medicine, Winston Salem, NC, USA
    Am J Epidemiol 160:741-9. 2004
    ..79, 95% confidence interval: 1.24, 2.58 per standard-deviation increase; p < 0.01). The amount of adipose tissue stored in the intraabdominal cavity is an important, independent risk factor for MI in well-functioning, elderly women...
  70. ncbi request reprint Bone density and hemoglobin levels in older persons: results from the InCHIANTI study
    Matteo Cesari
    Sticht Center on Aging, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, North Carolina, NC 27157, USA
    Osteoporos Int 16:691-9. 2005
    ..The bone loss associated with hemoglobin levels mainly occurs in the cortical bone. Women with lower hemoglobin levels demonstrate a higher bone loss than male counterparts...
  71. ncbi request reprint Reliability of the 400-m usual-pace walk test as an assessment of mobility limitation in older adults
    Yves M Rolland
    Sticht Center on Aging, Section on Gerontology and Geriatric Medicine, Department of Internal Medicine, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    J Am Geriatr Soc 52:972-6. 2004
    ..To assess the test-retest reliability of the 400-m usual-pace walk test (400-MWT), and to determine whether the 4-m walk test predicts inability to walk 400 m...
  72. ncbi request reprint Physical performance measures as predictors of mortality in a cohort of community-dwelling older French women
    Yves Rolland
    Service de Medecine Interne et de Gerontologie Clinique, Hopital La Grave Casselardit, 31300, Toulouse, France
    Eur J Epidemiol 21:113-22. 2006
    ..Increased risk of death was partly explained by baseline health status and was absent in the healthiest elderly...
  73. ncbi request reprint Anemia is associated with disability and decreased physical performance and muscle strength in the elderly
    Brenda W J H Penninx
    Sticht Center on Aging, Section on Gerontology and Geriatric Medicine, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    J Am Geriatr Soc 52:719-24. 2004
    ..To examine the association between anemia and disability, physical performance, and muscle strength in older persons...
  74. ncbi request reprint Predictors of combined cognitive and physical decline
    Hal H Atkinson
    Roena Kulynych Center for Memory and Cognition Research, Sticht Center on Aging, Department of Internal Medicine, Section on Gerontology and Geriatric Medicine, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    J Am Geriatr Soc 53:1197-202. 2005
    ..To determine the incidence and correlates of combined declines in cognitive and physical performance...
  75. ncbi request reprint Hemoglobin levels and skeletal muscle: results from the InCHIANTI study
    Matteo Cesari
    Sticht Center on Aging, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    J Gerontol A Biol Sci Med Sci 59:249-54. 2004
    ..Anemia is associated with reduced physical performance and muscle strength. The aim of the study was to explore whether anemia and hemoglobin levels are associated with differences in quantitative and qualitative measures of muscle and fat...
  76. ncbi request reprint Inflammatory markers and physical performance in older persons: the InCHIANTI study
    Matteo Cesari
    Sticht Center on Aging, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    J Gerontol A Biol Sci Med Sci 59:242-8. 2004
    ..The aim of this study is to evaluate the relationship between several inflammatory markers and physical performance in an older population...
  77. ncbi request reprint Correlation between two markers of inflammation, serum C-reactive protein and interleukin 6, and indices of oxidative stress in patients with high risk of cardiovascular disease
    Dora Il'yasova
    Duke Comprehensive Cancer Center, 2424 Erwin Rd, Hock Bldg, Ste 602, Box 2949, Durham, NC 27710, USA
    Biomarkers 13:41-51. 2008
    ..Urinary levels of F2-IsoP and serum levels of CRP represent appropriate biomarkers for future studies of inflammation and oxidative status in humans...
  78. ncbi request reprint Inflammatory markers and onset of cardiovascular events: results from the Health ABC study
    Matteo Cesari
    Sticht Center on Aging, Wake Forest University School of Medicine, Medical Center Blvd, Winston Salem, NC 27157, USA
    Circulation 108:2317-22. 2003
    ..Inflammation plays an important role in cardiovascular disease. The aim of this study is to investigate the predictive value of several inflammatory markers on the incidence of cardiovascular events in well-functioning older persons...
  79. ncbi request reprint Cognitive function, gait speed decline, and comorbidities: the health, aging and body composition study
    Hal H Atkinson
    Department of Internal Medicine, Section on Gerontology and Geriatric Medicine, Claude D Pepper Older Americans Independence Center, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    J Gerontol A Biol Sci Med Sci 62:844-50. 2007
    ..This study examines the relationship between cognitive function and subsequent gait speed decline among high-functioning older adults...
  80. pmc Relationship between the occiput-wall distance and physical performance in the elderly: a cross sectional study
    Raffaele Antonelli-Incalzi
    Cattedra di Geriatria, Universita Campus BioMedico, 00128 Roma, Italy
    Aging Clin Exp Res 19:207-12. 2007
    ..The occiput-wall distance (OWD), a measure of kyphosis, has been associated with postural instability, osteoporosis, disability and depression. The association between OWD and measures of physical performance was evaluated...
  81. ncbi request reprint Angiotensin-converting enzyme inhibition, body composition, and physical performance in aged rats
    Christy S Carter
    Sticht Center on Aging, Department of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    J Gerontol A Biol Sci Med Sci 59:416-23. 2004
    ..These results suggest that ACE inhibition may prevent age-related declines in physical performance, which may be mediated by a reduction in body fat mass...
  82. ncbi request reprint Physical function, physical activity and recent falls. Results from the "Invecchiamento e Longevità nel Sirente (ilSIRENTE)" Study
    Irene Mangani
    Department of Critical Care Medicine and Surgery, Unit of Geriatric Medicine, University of Florence, Florence, Italy
    Aging Clin Exp Res 20:234-41. 2008
    ....
  83. pmc Association between vitamin D status and physical performance: the InCHIANTI study
    Denise K Houston
    Department of Internal Medicine, Section on Gerontology and Geriatric Medicine, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    J Gerontol A Biol Sci Med Sci 62:440-6. 2007
    ..Vitamin D status has been hypothesized to play a role in musculoskeletal function. Using data from the InCHIANTI study, we examined the association between vitamin D status and physical performance...
  84. ncbi request reprint Depression and adverse drug reactions among hospitalized older adults
    Graziano Onder
    Centro Medicina dell Invecchiamento, Universita Cattolica del Sacro Cuore, Policlinico A Gemelli, L go Francesco Vito 1, 00168 Rome, Italy
    Arch Intern Med 163:301-5. 2003
    ..The aim of this study was to assess whether depression may be a risk factor for adverse drug reactions (ADRs) among hospitalized older adults...
  85. ncbi request reprint Adverse drug reactions as cause of hospital admissions: results from the Italian Group of Pharmacoepidemiology in the Elderly (GIFA)
    Graziano Onder
    Section of Gerontology and Geriatrics, Sticht Center on Aging, Wake Forest University Baptist Medical Center, Winston Salem, North Carolina, USA
    J Am Geriatr Soc 50:1962-8. 2002
    ....

Research Grants1

  1. Oxidative damage, disability and mortality in elders
    Matteo Cesari; Fiscal Year: 2007
    ....