JOHN CEBRA

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. ncbi request reprint Influences of microbiota on intestinal immune system development
    J J Cebra
    Department of Biology, The University of Pennsylvania, Philadelphia 19104 6018, USA
    Am J Clin Nutr 69:1046S-1051S. 1999
  2. pmc Orally administered microencapsulated reovirus can bypass suckled, neutralizing maternal antibody that inhibits active immunization of neonates
    S B Periwal
    Department of Biology, University of Pennsylvania, Philadelphia 19104 6018, USA
    J Virol 71:2844-50. 1997
  3. pmc Gut colonization of mice with actA-negative mutant of Listeria monocytogenes can stimulate a humoral mucosal immune response
    M Manohar
    Department of Biology, University of Pennsylvania, Philadelphia, Pennysylvania 19104-6018, USA
    Infect Immun 69:3542-9. 2001
  4. pmc Timing, localization, and persistence of colonization by segmented filamentous bacteria in the neonatal mouse gut depend on immune status of mothers and pups
    H Q Jiang
    Department of Biology, University of Pennsylvania, Philadelphia 19104, USA
    Infect Immun 69:3611-7. 2001
  5. pmc B2 but not B1 cells can contribute to CD4+ T-cell-mediated clearance of rotavirus in SCID mice
    N Kushnir
    Department of Biology, University of Pennsylvania, Philadelphia 19104-6018, USA
    J Virol 75:5482-90. 2001

Collaborators

  • S E Coffin
  • C A Moser
  • N A Bos
  • N Kushnir
  • M Manohar
  • H Q Jiang
  • S B Periwal
  • D O Baumann
  • P A Offit
  • A W Zuercher
  • T J Speaker

Detail Information

Publications5

  1. ncbi request reprint Influences of microbiota on intestinal immune system development
    J J Cebra
    Department of Biology, The University of Pennsylvania, Philadelphia 19104 6018, USA
    Am J Clin Nutr 69:1046S-1051S. 1999
    ..Neonatal conventionally reared mice and germ-free, deliberately colonized adult mice (gnotobiotic mice) were used to examine the efficacy of certain intestinal microbes...
  2. pmc Orally administered microencapsulated reovirus can bypass suckled, neutralizing maternal antibody that inhibits active immunization of neonates
    S B Periwal
    Department of Biology, University of Pennsylvania, Philadelphia 19104 6018, USA
    J Virol 71:2844-50. 1997
    ..These observations seem relevant to the development of efficacious oral vaccines that also allow passive, protective immunity via suckled maternal antibodies while permitting active oral immunization of neonates...
  3. pmc Gut colonization of mice with actA-negative mutant of Listeria monocytogenes can stimulate a humoral mucosal immune response
    M Manohar
    Department of Biology, University of Pennsylvania, Philadelphia, Pennysylvania 19104-6018, USA
    Infect Immun 69:3542-9. 2001
    ..monocytogenes. We detected IgA binding to antigenic proteins with molecular masses of 96, 60, 40, and 14 kDa in the Listeria sonicates...
  4. pmc Timing, localization, and persistence of colonization by segmented filamentous bacteria in the neonatal mouse gut depend on immune status of mothers and pups
    H Q Jiang
    Department of Biology, University of Pennsylvania, Philadelphia 19104, USA
    Infect Immun 69:3611-7. 2001
    ..Nevertheless, it is evident that the timing, localization, and persistence of colonization of the neonatal gut by SFB depends on the immune status of both mothers and pups...
  5. pmc B2 but not B1 cells can contribute to CD4+ T-cell-mediated clearance of rotavirus in SCID mice
    N Kushnir
    Department of Biology, University of Pennsylvania, Philadelphia 19104-6018, USA
    J Virol 75:5482-90. 2001
    ..Reconstitution of RV-infected SCID mice with B1 cells results in the outgrowth of contaminating, donor CD4+ T cells that are unable to clear RV, possibly because their oligoclonal specificities may be ineffective against RV antigens...

Research Grants15

  1. REOVIRUSES AS PROBES OF GUT MUCOSAL T-CELL RESPONSE
    JOHN CEBRA; Fiscal Year: 1993
    ..Particularly, we will seek to define the bases for their accumulation in infected liver, target cell preferences, contributions to liver pathology, and interactions with adoptively transferred T cell subsets in vivo...
  2. REOVIRUSES AS PROBES OF GUT MUCOSAL T-CELL RESPONSE
    JOHN CEBRA; Fiscal Year: 1992
    ..Particularly, we will seek to define the bases for their accumulation in infected liver, target cell preferences, contributions to liver pathology, and interactions with adoptively transferred T cell subsets in vivo...
  3. REOVIRUSES AS PROBES OF GUT MUCOSAL T-CELL RESPONSE
    JOHN CEBRA; Fiscal Year: 1990
    ....
  4. REOVIRUSES AND PROBES OF MUCOSAL IMMUNE RESPONSES
    JOHN CEBRA; Fiscal Year: 2001
    ..The results of these analyses should be extremely relevant for the development of efficacious vaccines vs. respiratory pathogens. ..