RICHARD MOORE CAWTHON

Summary

Affiliation: University of Utah
Country: USA

Publications

  1. ncbi request reprint Association between telomere length in blood and mortality in people aged 60 years or older
    Richard M Cawthon
    Department of Human Genetics, University of Utah, Salt Lake City, UT 84112, USA
    Lancet 361:393-5. 2003
  2. pmc Telomere measurement by quantitative PCR
    Richard M Cawthon
    Department of Human Genetics, University of Utah, 15 N 2030 E, Room 2100, Salt Lake City, UT 84112, USA
    Nucleic Acids Res 30:e47. 2002
  3. pmc Telomere length measurement by a novel monochrome multiplex quantitative PCR method
    Richard M Cawthon
    Department of Human Genetics, University of Utah, Salt Lake City, UT 84112, USA
    Nucleic Acids Res 37:e21. 2009
  4. ncbi request reprint Sodium bicarbonate cotransporter polymorphisms are associated with baseline and 10-year follow-up blood pressures
    Steven C Hunt
    Cardiovascular Genetics Division, Department of Human Genetics, University of Utah School of Medicine, Salt Lake City, Utah, USA
    Hypertension 47:532-6. 2006
  5. ncbi request reprint Upstream stimulatory factor 1 associated with familial combined hyperlipidemia, LDL cholesterol, and triglycerides
    Hilary Coon
    Neurodevelopmental Genetics Project, Department of Psychiatry, University of Utah, Salt Lake City, UT 84108, USA
    Hum Genet 117:444-51. 2005
  6. ncbi request reprint Model-fitting and linkage analysis of sodium-lithium countertransport
    Sandra J Hasstedt
    Department of Human Genetics, University of Utah, Salt Lake City, UT 84112 5330, USA
    Eur J Hum Genet 12:1055-61. 2004
  7. ncbi request reprint Linkage of serum creatinine and glomerular filtration rate to chromosome 2 in Utah pedigrees
    Steven C Hunt
    Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, Utah 84108, USA
    Am J Hypertens 17:511-5. 2004
  8. ncbi request reprint Genome-wide multipoint parametric linkage analysis of pulse pressure in large, extended utah pedigrees
    Nicola J Camp
    Genetic Epidemiology, Department of Medical Informatics, University of Utah School of Medicine, 391 Chipeta Way, Suite D, Salt Lake City, UT 84108 1206, USA
    Hypertension 42:322-8. 2003
  9. ncbi request reprint Linkage of creatinine clearance to chromosome 10 in Utah pedigrees replicates a locus for end-stage renal disease in humans and renal failure in the fawn-hooded rat
    Steven C Hunt
    Cardiovascular Genetics, Department of Internal Medicine, University of Utah School of Medicine, 410 Chipeta Way, Salt Lake City, UT 84108, USA
    Kidney Int 62:1143-8. 2002
  10. pmc Familial aggregation of survival and late female reproduction
    Ken R Smith
    Department of Family and Consumer Studies, University of Utah, Salt Lake City, 84112, USA
    J Gerontol A Biol Sci Med Sci 64:740-4. 2009

Research Grants

  1. Genomic Integrity, Aging, and Longevity
    Richard Cawthon; Fiscal Year: 2007

Detail Information

Publications11

  1. ncbi request reprint Association between telomere length in blood and mortality in people aged 60 years or older
    Richard M Cawthon
    Department of Human Genetics, University of Utah, Salt Lake City, UT 84112, USA
    Lancet 361:393-5. 2003
    ..0079), and an 8.54-fold higher mortality rate from infectious disease (1.52-47.9, p=0.015). These results lend support to the hypothesis that telomere shortening in human beings contributes to mortality in many age-related diseases...
  2. pmc Telomere measurement by quantitative PCR
    Richard M Cawthon
    Department of Human Genetics, University of Utah, 15 N 2030 E, Room 2100, Salt Lake City, UT 84112, USA
    Nucleic Acids Res 30:e47. 2002
    ..This assay will facilitate investigations of the biology of telomeres and the roles they play in the molecular pathophysiology of diseases and aging...
  3. pmc Telomere length measurement by a novel monochrome multiplex quantitative PCR method
    Richard M Cawthon
    Department of Human Genetics, University of Utah, Salt Lake City, UT 84112, USA
    Nucleic Acids Res 37:e21. 2009
    ..844) than with our original singleplex method (R(2) = 0.677). Multiplex T/S results from independent runs on different days were highly reproducible (R(2) = 0.91)...
  4. ncbi request reprint Sodium bicarbonate cotransporter polymorphisms are associated with baseline and 10-year follow-up blood pressures
    Steven C Hunt
    Cardiovascular Genetics Division, Department of Human Genetics, University of Utah School of Medicine, Salt Lake City, Utah, USA
    Hypertension 47:532-6. 2006
    ..These results additionally confirm the involvement of SLC4A5 with blood pressure control, although the mechanism is still unclear...
  5. ncbi request reprint Upstream stimulatory factor 1 associated with familial combined hyperlipidemia, LDL cholesterol, and triglycerides
    Hilary Coon
    Neurodevelopmental Genetics Project, Department of Psychiatry, University of Utah, Salt Lake City, UT 84108, USA
    Hum Genet 117:444-51. 2005
    ..This study replicates the involvement of USF1 in FCHL and related lipid traits in a family sample not ascertained for FCHL...
  6. ncbi request reprint Model-fitting and linkage analysis of sodium-lithium countertransport
    Sandra J Hasstedt
    Department of Human Genetics, University of Utah, Salt Lake City, UT 84112 5330, USA
    Eur J Hum Genet 12:1055-61. 2004
    ..Using the inferred model, lod scores >2 were obtained for D3S3038, D11S4464, and D10S677 for the BMI-responsive locus, and for D8S1048 for the TG-responsive locus...
  7. ncbi request reprint Linkage of serum creatinine and glomerular filtration rate to chromosome 2 in Utah pedigrees
    Steven C Hunt
    Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, Utah 84108, USA
    Am J Hypertens 17:511-5. 2004
    ..This can lead to a loss in power to detect linkage. Therefore, in this study we also investigated serum creatinine and estimated glomerular filtration rates (GFR), both of which are more reliably measured...
  8. ncbi request reprint Genome-wide multipoint parametric linkage analysis of pulse pressure in large, extended utah pedigrees
    Nicola J Camp
    Genetic Epidemiology, Department of Medical Informatics, University of Utah School of Medicine, 391 Chipeta Way, Suite D, Salt Lake City, UT 84108 1206, USA
    Hypertension 42:322-8. 2003
    ..In conclusion, our results suggest that pulse pressure might be of use for identifying genes involved in blood pressure phenotypes and arterial aging...
  9. ncbi request reprint Linkage of creatinine clearance to chromosome 10 in Utah pedigrees replicates a locus for end-stage renal disease in humans and renal failure in the fawn-hooded rat
    Steven C Hunt
    Cardiovascular Genetics, Department of Internal Medicine, University of Utah School of Medicine, 410 Chipeta Way, Salt Lake City, UT 84108, USA
    Kidney Int 62:1143-8. 2002
    ..4. An important question is whether this region can be detected in healthy subjects prior to onset of ESRD by examining creatinine clearance as an indicator of early renal damage...
  10. pmc Familial aggregation of survival and late female reproduction
    Ken R Smith
    Department of Family and Consumer Studies, University of Utah, Salt Lake City, 84112, USA
    J Gerontol A Biol Sci Med Sci 64:740-4. 2009
    ..These results support the hypothesis that late female fertility and slow somatic aging may be promoted by the same genetic variants...
  11. pmc Gene expression profiles associated with aging and mortality in humans
    Richard A Kerber
    Department of Oncological Sciences, 2000 Circle of Hope, Salt Lake City, UT 84112 5550, USA
    Aging Cell 8:239-50. 2009
    ..These observations may lead to new insights regarding the genetic contribution to exceptional longevity...

Research Grants2

  1. Genomic Integrity, Aging, and Longevity
    Richard Cawthon; Fiscal Year: 2007
    ..Therefore, this research is likely to speed the development of medical interventions that slow aging and extend the duration of healthy adult life. ..