Research Topics
| Carlos A CastroSummaryAffiliation: University of Pittsburgh Country: USA Publications
| Collaborators |
Detail Information
Publications
Systems biology discoveries using non-human primate pluripotent stem and germ cells: novel gene and genomic imprinting interactions as well as unique expression patternsAhmi Ben-Yehudah
Pittsburgh Development Center, 204 Craft Avenue, Pittsburgh, PA 15213, USA
Stem Cell Res Ther 1:24. 2010..In this review, we consider the mRNAs and novel genes with unique expression and imprinting patterns that were discovered using systems biology approaches with primate pluripotent stem and germ cells...
Semiquantitative histopathology and 3D magnetic resonance microscopy as collaborative platforms for tissue identification and comparison within teratomas derived from pedigreed primate embryonic stem cellsCarlos A Castro
Pittsburgh Development Center, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
Stem Cell Res 5:201-11. 2010..MRM provides rapid quantitative imaging of intact teratomas that complements histology and identifies sites of interest for additional biological studies...
Establishment and characterization of baboon embryonic stem cell lines: an Old World Primate model for regeneration and transplantation researchCalvin R Simerly
Division of Developmental and Regenerative Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh, Pittsburgh, PA 15213, USA
Stem Cell Res 2:178-87. 2009..They have been grown continuously for >430 and 290 days, respectively. Teratomas from both lines have all three germ layers. Availabilities of these BabESCs represent another important resource for stem cell biologists...
Pluripotency genes overexpressed in primate embryonic stem cells are localized on homologues of human chromosomes 16, 17, 19, and XAhmi Ben-Yehudah
Pittsburgh Development Center, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
Stem Cell Res 4:25-37. 2010....
Evaluating protocols for embryonic stem cell differentiation into insulin-secreting beta-cells using insulin II-GFP as a specific and noninvasive reporterAhmi Ben-Yehudah
Department of Obstetrics, Gynecology, and Reproductive Sciences, Pittsburgh Development Center, Magee Womens Research Institute and Foundation, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
Cloning Stem Cells 11:245-57. 2009..Therefore, improved beta-cells differentiation protocols are needed, and these insulin II GFP cells may prove to be an important tool to accelerate this process...
Human amniotic epithelial cells are reprogrammed more efficiently by induced pluripotency than adult fibroblastsCharles A Easley
Division of Developmental and Regenerative Medicine, Departments of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh, Pittsburgh, PA 15213, USA
Cell Reprogram 14:193-203. 2012....
Human IL-12 p40 as a reporter gene for high-throughput screening of engineered mouse embryonic stem cellsLeonardo D'Aiuto
Department of Cell Biology and Physiology, Pittsburgh Development Center, Magee Women s Research Institute, University of Pittsburgh School of Medicine, PA 15261, USA
BMC Biotechnol 8:52. 2008....
Pedigreed primate embryonic stem cells express homogeneous familial gene profilesChristopher S Navara
Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh Development Center, Magee Womens Research Institute and Foundation, Pittsburgh, Pennsylvania, USA
Stem Cells 25:2695-704. 2007..These similarities to mouse ESCs suggest that heterogeneities found among hESCs likely result from their disparate origins rather than intrinsic biological limitations with primate embryonic stem cells...
Assisted Reproductive Technologies (ART) with baboons generate live offspring: a nonhuman primate model for ART and reproductive sciencesCalvin R Simerly
Division of Developmental and Regenerative Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, Pittsburgh Development Center Magee Womens Research Institute, University of Pittsburgh, Pittsburgh, PA 15213, USA
Reprod Sci 17:917-30. 2010..These results have implications for ART outcomes, embryonic stem cell (ESC) derivation, and reproductive sciences...
