Research Topics
| S A CastellonSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
Apathy, depression, and cognitive performance in HIV-1 infectionS A Castellon
Department of Psychology, University of California Los Angeles 90024, USA
J Neuropsychiatry Clin Neurosci 10:320-9. 1998..Total BDI scores showed a less consistent relationship with neurocognitive performance, suggesting that somatic symptomatology is diagnostically ambiguous among HIV-infected subjects...
Breast cancer treatment and cognitive functioning: current status and future challenges in assessmentSteven A Castellon
Greater Los Angeles VA Healthcare System, Los Angeles, CA, USA
Breast Cancer Res Treat 92:199-206. 2005
Neurocognitive performance in breast cancer survivors exposed to adjuvant chemotherapy and tamoxifenSteven A Castellon
Department of Psychiatry and Biobehavioral Sciences, UCLA School of Medicine, Los Angeles, CA, USA
J Clin Exp Neuropsychol 26:955-69. 2004..We highlight ways in which these data converge with other recent studies to suggest that systemic chemotherapy, especially in combination with tamoxifen, can have adverse yet subtle effects on cognitive functioning...
Components of depression in HIV-1 infection: their differential relationship to neurocognitive performanceSteven A Castellon
Department of Psychiatry and Biobehavioral Sciences, University of California Los Angeles, Los Angeles, CA, USA
J Clin Exp Neuropsychol 28:420-37. 2006..The association between disturbance in mood and motivation and neurocognitive compromise may suggest that each are sequelae of disease specific mechanisms...
Neuropsychiatric disturbance is associated with executive dysfunction in HIV-1 infectionS A Castellon
Department of Psychiatry, UCLA School of Medicine, USA
J Int Neuropsychol Soc 6:336-47. 2000..In HIV/AIDS, the disruption of frontal-subcortical circuits may be a common mechanism causing both executive dysfunction and NP disturbance...
Dual task performance in HIV-1 infectionC H Hinkin
Department of Psychiatry and Biobehavioral Sciences, UCLA School of Medicine, CA 90024, USA
J Clin Exp Neuropsychol 22:16-24. 2000..These results suggest that HIV-1 infection leads to deficits in divided attention and the simultaneous processing of competing stimuli, deficits which have been linked to disruption of the anterior attentional system...
Computerized and traditional stroop task dysfunction in HIV-1 infectionC H Hinkin
Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles UCLA School of Medicine and VA Los Angeles Health Care System, 90024, USA
Neuropsychology 13:306-16. 1999..These data suggest that HIV infection may result in deficient response inhibition, possibly secondary to frontostriatal dysfunction and dopaminergic alterations...
Methylphenidate improves HIV-1-associated cognitive slowingC H Hinkin
Department of Psychiatry and Behavioral Sciences, UCLA School of Medicine, Los Angeles 90024, USA
J Neuropsychiatry Clin Neurosci 13:248-54. 2001..However, results suggest clinicians should consider reserving the use of MPH for patients with more pronounced cognitive and affective deficits...
Depression predicts procedural but not episodic memory in HIV-1 infectionA D Kalechstein
Department of Psychiatry and Biobehavioral Sciences, University of California Los Angeles Neuropsychiatric Institute and Hospital, USA
J Clin Exp Neuropsychol 20:529-35. 1998..These findings underscore the complex interplay between neuropsychiatric and neuropsychological symptomatology in HIV-1 infection...
Neuropsychiatric aspects of HIV infection among older adultsC H Hinkin
Department of Psychiatry and Biobehavioral Sciences, UCLA School of Medicine, 760 Westwood Plaza, Room C8 747, Los Angeles, CA 90024, USA
J Clin Epidemiol 54:S44-52. 2001....
Adherence to antiretroviral medications in HIV: differences in data collected via self-report and electronic monitoringAndrew J Levine
Neuropsychiatric Institute, University of California, Los Angeles, CA, USA
Health Psychol 25:329-35. 2006..These findings lend support for using both EM and SR methods; however, study design (e.g., length) and other factors (e.g., cognitive status, cost) should be considered...
Drug use and medication adherence among HIV-1 infected individualsCharles H Hinkin
David Geffen School of Medicine, University of California at Los Angeles, 760 Westwood Plaza, Room C8 747, Los Angeles, CA 90024, USA
AIDS Behav 11:185-94. 2007..These data suggest that it is the acute effects of intoxication, rather than stable features that may be characteristic of the drug-using populace, which leads to difficulties with medication adherence...
Altered frontocortical, cerebellar, and basal ganglia activity in adjuvant-treated breast cancer survivors 5-10 years after chemotherapyDaniel H S Silverman
Department of Molecular and Medical Pharmacology, University of California, David Geffen School of Medicine, Los Angeles, CA 90095 6942, USA
Breast Cancer Res Treat 103:303-11. 2007..To explore the relationship of regional cerebral blood flow and metabolism with cognitive function and past exposure to chemotherapy for breast cancer...
Age-associated predictors of medication adherence in HIV-positive adults: health beliefs, self-efficacy, and neurocognitive statusTerry R Barclay
Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, Los Angeles, CA 90095, USA
Health Psychol 26:40-9. 2007..In this study, a theoretical framework encompassing demographic characteristics, health beliefs/attitudes, treatment self-efficacy, and neurocognitive status was examined in relationship to highly active antiretroviral therapy adherence...
Relationship between psychiatric status and frontal-subcortical systems in HIV-infected individualsMichael A Cole
Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, California 90095, USA
J Int Neuropsychol Soc 13:549-54. 2007..Thus, these findings suggest that apathy and irritability, but not depression and anxiety, are likely associated with the effects of HIV on frontal-subcortical circuitry...
Aging, neurocognition, and medication adherence in HIV infectionMark L Ettenhofer
Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, USA
Am J Geriatr Psychiatry 17:281-90. 2009..To evaluate the hypothesis that poor adherence to highly active antiretroviral treatment (HAART) would be more strongly related to cognitive impairment among older than among younger HIV-seropositive adults...
Neurocognition in individuals co-infected with HIV and hepatitis CCharles H Hinkin
David Geffen School of Medicine, University of California, Los Angeles, 760 Westwood Plaza, Room C8 747, Los Angeles, CA 90024, USA
J Addict Dis 27:11-7. 2008..Finally, we discuss implications of these findings and potential future directions for research in this area...
The effect of recent stimulant use on sustained attention in HIV-infected adultsAndrew J Levine
University of California, Los Angeles, Neuropsychiatric Institute, USA
J Clin Exp Neuropsychol 28:29-42. 2006..The results indicate that recent stimulant use among HIV-infected adults adversely affects sustained attention...
Reciprocal prediction of medication adherence and neurocognition in HIV/AIDSMark L Ettenhofer
Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, University of California at Los Angeles, CA, USA
Neurology 74:1217-22. 2010..However, little is known about the predictive pathways linking medication adherence with cognitive ability...
Variations in patterns of highly active antiretroviral therapy (HAART) adherenceAndrew J Levine
Neuropsychiatric Institute, University of California, Los Angeles, California 90024 1759, USA
AIDS Behav 9:355-62. 2005..The results of the current study indicate that distinct subgroups of adherers may exist, and suggest that interventions designed to improve adherence can be designed to accommodate this variability in behavior...
Estrogen, tamoxifen, and the brainPatricia A Ganz
University of California at Los Angeles (UCLA) School of Medicine, and Jonsson Comprehensive Cancer Center at UCLA, 90095-6900, USA
J Natl Cancer Inst 94:547-9. 2002
Medication adherence in HIV-infected adults: effect of patient age, cognitive status, and substance abuseCharles H Hinkin
Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, University of California at Los Angeles, and Psychology Service, VA Greater Los Angeles Health Care System, 90024, USA
AIDS 18:S19-25. 2004..To examine the predictors of antiretroviral adherence among HIV-infected adults, with a particular focus on advancing age, neuropsychological dysfunction, and substance abuse...
Perceptual span deficits in adults with HIVDavid J Hardy
Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles 90024, USA
J Int Neuropsychol Soc 10:135-40. 2004..The present results illustrate a new type of attentional deficit in HIV and show the impact of HIV on cognition at an earlier point in information processing than has been previously reported...
Verbal and spatial working memory performance among HIV-infected adultsCharles H Hinkin
Department of Psychiatry and Behavioral Sciences, UCLA School of Medicine, Los Angeles, CA 90024, USA
J Int Neuropsychol Soc 8:532-8. 2002..These findings implicate central executive dysfunction as a likely substrate and provide the basis for hypothesizing that decline in working memory may contribute to other HIV-associated neuropsychological deficits...
Medication adherence among HIV+ adults: effects of cognitive dysfunction and regimen complexityC H Hinkin
Department of Psychiatry and Biobehavioral Sciences, UCLA School of Medicine, Los Angeles, CA 90024, USA
Neurology 59:1944-50. 2002..e., at least 90 to 95% of doses taken), viral replication may ensue and drug-resistant strains of the virus may emerge...
Sensation seeking and visual selective attention in adults with HIV/AIDSDavid J Hardy
Department of Psychology, Loyola Marymount University, Los Angeles, CA 90045, USA
AIDS Behav 12:930-4. 2008..Furthermore, sensation seeking differences might explain certain inconsistencies in the HIV neuropsychology literature...
Risky decision making assessed with the gambling task in adults with HIVDavid J Hardy
Department of Psychology, Loyola Marymount University, and the VA Greater Los Angeles Health Care System, CA 90045 2659, USA
Neuropsychology 20:355-60. 2006..These findings indicate the usefulness of the gambling task as a laboratory tool to examine risky decision making and cognition in the HIV population...
Screening for drug and alcohol abuse among older adults using a modified version of the CAGEC H Hinkin
Department of Psychiatry and Biobehavioral Sciences, UCLA School of Medicine, Los Angeles, CA 90024, USA
Am J Addict 10:319-26. 2001..Given the ease of administration and sensitivity to both alcohol and drug abuse, these data suggest that the modified CAGE is well suited as a screening instrument for geriatric drug and alcohol abuse...
Neuropsychological aspects of coinfection with HIV and hepatitis C virusRobin C Hilsabeck
Psychology Service, South Texas Veterans Health Care System, San Antonio, TX 78229 4404, USA
Clin Infect Dis 41:S38-44. 2005..This review summarizes what is known about neuropsychological aspects of monoinfection with HIV and HCV, as well as coinfection, discusses implications of these findings, and suggests future directions for this research area...
