Corey Casper

Summary

Affiliation: University of Washington
Country: USA

Publications

  1. ncbi request reprint Condom use and the prevention of genital herpes acquisition
    Corey Casper
    Department of Medicine, University of Washington, Seattle 98122, USA
    Herpes 9:10-4. 2002
  2. pmc Valganciclovir for suppression of human herpesvirus-8 replication: a randomized, double-blind, placebo-controlled, crossover trial
    Corey Casper
    Department of Medicine, University of Washington, Washington, USA
    J Infect Dis 198:23-30. 2008
  3. pmc Frequent and asymptomatic oropharyngeal shedding of human herpesvirus 8 among immunocompetent men
    Corey Casper
    Department of Medicine, University of Washington, Seattle, WA, USA
    J Infect Dis 195:30-6. 2007
  4. ncbi request reprint The use of antiviral drugs in the prevention and treatment of Kaposi sarcoma, multicentric Castleman disease and primary effusion lymphoma
    C Casper
    University of Washington Virology Research Clinic, 600 Broadway, Suite 400, Seattle, WA 98122, USA
    Curr Top Microbiol Immunol 312:289-307. 2007
  5. ncbi request reprint Human herpesvirus 8 infection among adolescents in the REACH cohort
    Corey Casper
    Departments of Medicine, Laboratory Medicine, and Epidemiology, University of Washington, Seattle, USA
    Arch Pediatr Adolesc Med 160:937-42. 2006
  6. ncbi request reprint Defining a role for antiviral drugs in the treatment of persons with HHV-8 infection
    C Casper
    The Department of Medicine, University of Washington, and The Program in Infectious Disease, Fred Hutchinson Cancer Research Center, Seattle, WA 98122, USA
    Herpes 13:42-7. 2006
  7. pmc HIV serodiscordant sex partners and the prevalence of human herpesvirus 8 infection among HIV negative men who have sex with men: baseline data from the EXPLORE Study
    C Casper
    Department of Medicine, The University of Washington, Seattle, WA, USA
    Sex Transm Infect 82:229-35. 2006
  8. ncbi request reprint The aetiology and management of Castleman disease at 50 years: translating pathophysiology to patient care
    Corey Casper
    Department of Medicine, Division of Infectious Disease, University of Washington School of Medicine, and The Program in Infectious Disease, Fred Hutchinson Cancer Research Center, Seattle, WA 98122, USA
    Br J Haematol 129:3-17. 2005
  9. ncbi request reprint HIV infection and human herpesvirus-8 oral shedding among men who have sex with men
    Corey Casper
    Department of Medicine, The University of Washington, Seattle 98122, USA
    J Acquir Immune Defic Syndr 35:233-8. 2004
  10. ncbi request reprint Remission of HHV-8 and HIV-associated multicentric Castleman disease with ganciclovir treatment
    Corey Casper
    Department of Medicine, University of Washington School of Medicine, Seattle, USA
    Blood 103:1632-4. 2004

Detail Information

Publications36

  1. ncbi request reprint Condom use and the prevention of genital herpes acquisition
    Corey Casper
    Department of Medicine, University of Washington, Seattle 98122, USA
    Herpes 9:10-4. 2002
    ....
  2. pmc Valganciclovir for suppression of human herpesvirus-8 replication: a randomized, double-blind, placebo-controlled, crossover trial
    Corey Casper
    Department of Medicine, University of Washington, Washington, USA
    J Infect Dis 198:23-30. 2008
    ..In vitro and observational studies suggest that ganciclovir inhibits HHV-8 replication, but no randomized clinical trials have been conducted...
  3. pmc Frequent and asymptomatic oropharyngeal shedding of human herpesvirus 8 among immunocompetent men
    Corey Casper
    Department of Medicine, University of Washington, Seattle, WA, USA
    J Infect Dis 195:30-6. 2007
    ..Little is known about the clinical and virologic manifestations of human herpesvirus (HHV)-8 infection in immunocompetent persons in the absence of malignancy...
  4. ncbi request reprint The use of antiviral drugs in the prevention and treatment of Kaposi sarcoma, multicentric Castleman disease and primary effusion lymphoma
    C Casper
    University of Washington Virology Research Clinic, 600 Broadway, Suite 400, Seattle, WA 98122, USA
    Curr Top Microbiol Immunol 312:289-307. 2007
    ..A growing body of basic science, preclinical, and observational data suggests that antiviral medications may play an important role in the prevention and treatment of KSHV-associated disease...
  5. ncbi request reprint Human herpesvirus 8 infection among adolescents in the REACH cohort
    Corey Casper
    Departments of Medicine, Laboratory Medicine, and Epidemiology, University of Washington, Seattle, USA
    Arch Pediatr Adolesc Med 160:937-42. 2006
    ..We examined the prevalence and predictors of HHV-8 infection among adolescents with or at high risk for acquiring HIV infection...
  6. ncbi request reprint Defining a role for antiviral drugs in the treatment of persons with HHV-8 infection
    C Casper
    The Department of Medicine, University of Washington, and The Program in Infectious Disease, Fred Hutchinson Cancer Research Center, Seattle, WA 98122, USA
    Herpes 13:42-7. 2006
    ..This review discusses current evidence for the efficacy of antivirals against HHV-8 and proposes novel uses for such medications in HHV-8 treatment...
  7. pmc HIV serodiscordant sex partners and the prevalence of human herpesvirus 8 infection among HIV negative men who have sex with men: baseline data from the EXPLORE Study
    C Casper
    Department of Medicine, The University of Washington, Seattle, WA, USA
    Sex Transm Infect 82:229-35. 2006
    ..We sought to determine whether oral or anogenital contact with HIV discordant, or unknown serostatus sexual partners is associated with HHV-8 seroprevalence among HIV negative MSM...
  8. ncbi request reprint The aetiology and management of Castleman disease at 50 years: translating pathophysiology to patient care
    Corey Casper
    Department of Medicine, Division of Infectious Disease, University of Washington School of Medicine, and The Program in Infectious Disease, Fred Hutchinson Cancer Research Center, Seattle, WA 98122, USA
    Br J Haematol 129:3-17. 2005
    ..Finally, the natural history of CD and the myriad of therapeutic options are reviewed in the context of a unified model of CD pathophysiology, and continued areas of uncertainty are discussed...
  9. ncbi request reprint HIV infection and human herpesvirus-8 oral shedding among men who have sex with men
    Corey Casper
    Department of Medicine, The University of Washington, Seattle 98122, USA
    J Acquir Immune Defic Syndr 35:233-8. 2004
    ..8, 95% CI 1.0-22.8, P = 0.05), or with detectable oral leukocyte esterase (odds ratio 5.0, 95% CI 2.0-12.5, P < 0.01). CD4 count, antiretroviral therapy, and oral inflammation may influence HHV-8 oropharyngeal shedding...
  10. ncbi request reprint Remission of HHV-8 and HIV-associated multicentric Castleman disease with ganciclovir treatment
    Corey Casper
    Department of Medicine, University of Washington School of Medicine, Seattle, USA
    Blood 103:1632-4. 2004
    ..These data provide in vivo evidence for the utility of antiviral agents against HHV-8 in the management of MCD...
  11. ncbi request reprint Correlates of prevalent and incident Kaposi's sarcoma-associated herpesvirus infection in men who have sex with men
    Corey Casper
    Department of Medicine, University of Washington, Seattle, WA 98195, USA
    J Infect Dis 185:990-3. 2002
    ..Reporting > or =1 HIV-positive partner (OR, 5.9; 95% CI, 1.8-19.3), amyl nitrite use (OR, 7.0; 95% CI, 2.1-23.0), and lymphadenopathy in the past 6 months (OR, 7.7; 95% CI, 1.9-31.0) correlated with KSHV seroconversion...
  12. pmc Assessment of a combined testing strategy for detection of antibodies to human herpesvirus 8 (HHV-8) in persons with Kaposi's sarcoma, persons with asymptomatic HHV-8 infection, and persons at low risk for HHV-8 infection
    Corey Casper
    Department of Medicine, Virology Research Clinic, University of Washington School of Medicine, Box 359928, Seattle, WA 98195, USA
    J Clin Microbiol 40:3822-5. 2002
    ..15 to 0.35) where there was considerable overlap between HHV-8-infected and uninfected individuals. The sensitivity of the testing strategy was 88%, with a specificity of 97%...
  13. pmc Treatment with valacyclovir, famciclovir, or antiretrovirals reduces human herpesvirus-8 replication in HIV-1 seropositive men
    Ashok Cattamanchi
    Department of Medicine, University of Washington, Seattle, Washington, USA
    J Med Virol 83:1696-703. 2011
    ..In contrast, HAART was a potent inhibitor of HHV-8 replication. Studies of whether antiviral therapy in combination with ART will prevent HHV-8-associated disease appear warranted...
  14. pmc Persistent genital herpes simplex virus-2 shedding years following the first clinical episode
    Warren Phipps
    Department of Medicine, University of Washington, Seattle, Washington, USA
    J Infect Dis 203:180-7. 2011
    ..Rates of genital shedding initially decrease over time after infection, but data on long-term viral shedding are lacking...
  15. pmc Gender differences in clinical presentation and outcomes of epidemic Kaposi sarcoma in Uganda
    Warren Phipps
    Department of Medicine, University of Washington, Seattle, Washington, United States of America
    PLoS ONE 5:e13936. 2010
    ..To identify gender-related differences in KS presentation and outcomes, we evaluated the clinical manifestations and response in men and women with AIDS-associated KS in Uganda...
  16. pmc Clinical presentation and outcome of epidemic Kaposi sarcoma in Ugandan children
    Soren Gantt
    Seattle Children s Hospital, Seattle, WA, USA
    Pediatr Blood Cancer 54:670-4. 2010
    ..Kaposi sarcoma (KS) is one of the most common pediatric cancers in sub-Saharan Africa. Few data are available about the clinical presentation or response to treatment of children with epidemic (HIV-associated) KS...
  17. pmc The HIV protease inhibitor nelfinavir inhibits Kaposi's sarcoma-associated herpesvirus replication in vitro
    Soren Gantt
    Department of Pediatrics, University of Washington, Seattle, Washington, USA
    Antimicrob Agents Chemother 55:2696-703. 2011
    ..Nelfinavir may provide unique benefits for the prevention or treatment of HIV-associated KS and potentially other human herpesviruses by direct inhibition of replication...
  18. ncbi request reprint Reduced levels of neutralizing antibodies to Kaposi sarcoma-associated herpesvirus in persons with a history of Kaposi sarcoma
    Louise E Kimball
    Department of Pathobiology, University of Washington, and Program in Infectious Diseases, Fred Hutchinson Cancer Research Center, Seattle, 98109, USA
    J Infect Dis 189:2016-22. 2004
    ..The data from the present study suggest that NAb may play a role in the control of KSHV infection and the prevention of progression of KSHV infection to KS...
  19. pmc Persistent Kaposi sarcoma in the era of highly active antiretroviral therapy: characterizing the predictors of clinical response
    Huong Q Nguyen
    Department of Epidemiology, University of Washington, Seattle, Washington, USA
    AIDS 22:937-45. 2008
    ..To evaluate the role of highly active antiretroviral therapy and chemotherapy on tumor response among persons with AIDS-related Kaposi sarcoma and identify factors associated with response in a clinic setting...
  20. pmc New approaches to the treatment of human herpesvirus 8-associated disease
    Corey Casper
    Vaccine and Infectious Disease Institute, Fred Hutchinson Cancer Research Center, and the Department of Medicine, University of Washington, Seattle, Washington 98109, USA
    Rev Med Virol 18:321-9. 2008
    ..Finally, novel approaches to treatment and prevention are described, including antiviral agents, targeted molecular therapy and a combination of these modalities...
  21. ncbi request reprint Correlates of human herpesvirus-8 seropositivity among U.S. military members recently infected with human immunodeficiency virus
    Nancy F Crum
    Department of Medicine, Infectious Diseases Division, Naval Medical Center San Diego, San Diego, California 92134 1005, USA
    Sex Transm Dis 30:713-8. 2003
    ..Human herpesvirus 8 (HHV-8), the cause of Kaposi's sarcoma, is common among HIV-infected persons. The exact route of transmission of HHV-8 in various populations is still debated...
  22. pmc Clinical correlates of herpes simplex virus viremia among hospitalized adults
    William R Berrington
    Department of Medicine, University of Washington, Seattle, Washington, USA
    Clin Infect Dis 49:1295-301. 2009
    ..Quantification of herpes simplex virus (HSV) DNA in the peripheral blood is often used to evaluate patients suspected of having disseminated HSV infection. Few studies have examined the clinical correlates of HSV viremia among adults...
  23. doi request reprint An artesunate-containing antimalarial treatment regimen did not suppress cytomegalovirus viremia
    Soren Gantt
    Seattle Children s Hospital, Seattle, WA, USA University of Washington, Seattle, WA, USA Electronic address
    J Clin Virol 58:276-8. 2013
    ..Only a small number of case reports are available describing the clinical effects of artesunate on CMV infection, and these yielded inconsistent results...
  24. pmc HIV-specific CD8+ T cells from HIV+ individuals receiving HAART can be expanded ex vivo to augment systemic and mucosal immunity in vivo
    Aude G Chapuis
    Program in Immunology, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, Seattle, WA 98109, USA
    Blood 117:5391-402. 2011
    ....
  25. pmc Impact of HIV infection and Kaposi sarcoma on human herpesvirus-8 mucosal replication and dissemination in Uganda
    Christine Johnston
    Department of Medicine, University of Washington, Seattle, Washington, United States of America
    PLoS ONE 4:e4222. 2009
    ..Human herpesvirus-8 (HHV-8) replication is important both in transmission of HHV-8 and progression to KS. We characterized the sites and frequency of HHV-8 detection in Ugandans with and without HIV and KS...
  26. doi request reprint The increasing burden of HIV-associated malignancies in resource-limited regions
    Corey Casper
    Vaccine and Infectious Disease, Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
    Annu Rev Med 62:157-70. 2011
    ..The pathogenesis of HIV-associated cancers is considered in relation to potential strategies for their prevention and treatment...
  27. ncbi request reprint Gamma delta+ T cells involvement in viral immune control of chronic human herpesvirus 8 infection
    Serge Barcy
    Department of Laboratory Medicine, University of Washington, Seattle, WA 98109, USA
    J Immunol 180:3417-25. 2008
    ..These data indicate that gammadelta T cells play a role in both innate and adaptive T cell responses against HHV-8 in immunocompetent individuals...
  28. pmc Predictors of survival after a diagnosis of non-Hodgkin lymphoma in a resource-limited setting: a retrospective study on the impact of HIV infection and its treatment
    Moses H Bateganya
    Department of Global Health, University of Washington, Seattle, WA 98104, USA
    J Acquir Immune Defic Syndr 56:312-9. 2011
    ..We examined factors associated with survival among patients with newly diagnosed non-Hodgkin lymphoma (NHL) in Uganda...
  29. ncbi request reprint Cutaneous T-cell lymphoma in sub-Saharan Africa
    Matthew Ulrickson
    Clinical Research Division, Fred Hutchinson Cancer Research Center, and Department of Medicine, University of Washington, Seattle, Washington, USA
    J Natl Compr Canc Netw 11:275-80. 2013
    ..Areas for future investigation that can improve the care of patients in this region are identified...
  30. pmc A case report of dengue virus infection and acalculous cholecystitis in a pregnant returning traveler
    William R Berrington
    Department of Medicine, Division of Allergy and Infectious Disease, University of Washington, Seattle, WA 98195, USA
    Travel Med Infect Dis 5:251-3. 2007
    ..Travel during pregnancy to dengue-endemic areas poses a risk to both mother and fetus. Pregnancies complicated by dengue infection require close monitoring for potential maternal and fetal complications...
  31. pmc Paradoxical immune reconstitution inflammatory syndrome in HIV-infected patients treated with combination antiretroviral therapy after AIDS-defining opportunistic infection
    Chad J Achenbach
    Department of Medicine, Feinberg School of Medicine, Division of Infectious Diseases and Center for Global Health, Northwestern University, Chicago, Illinois 60611, USA
    Clin Infect Dis 54:424-33. 2012
    ..The incidence of immune reconstitution inflammatory syndrome (IRIS) when antiretroviral therapy (ART) is initiated after an AIDS-defining opportunistic infection (OI) is uncertain and understudied for the most common OIs...
  32. pmc How I treat influenza in patients with hematologic malignancies
    Corey Casper
    Vaccine and Infectious Disease Institute, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Blood 115:1331-42. 2010
    ..We also summarize infection control and vaccination strategies for patients, family members, and caregivers...
  33. doi request reprint Human herpesvirus 8-associated neoplasms: the roles of viral replication and antiviral treatment
    Soren Gantt
    Department of Pediatrics, University of Washington, Seattle Children s Hospital, Seattle, WA 98101, USA
    Curr Opin Infect Dis 24:295-301. 2011
    ..In this review, we highlight the importance of human herpesvirus 8 (HHV-8) lytic replication and the potential for antiviral therapies to prevent or treat HHV-8-related neoplasms...
  34. doi request reprint Insights into the broad cellular effects of nelfinavir and the HIV protease inhibitors supporting their role in cancer treatment and prevention
    Soren Gantt
    aDepartment of Pediatrics bDepartment of Medicine cDepartment of Epidemiology dDepartment of Global Health, University of Washington eSeattle Children s Hospital, University of Washington School of Medicine fVaccine and Infectious Disease gPublic Health Sciences hClinical Research Divisions, Fred Hutchinson Cancer Research Center, Seattle, Washington iSidney Kimmel Cancer Center at Johns Hopkins University, Baltimore, Maryland, USA
    Curr Opin Oncol 25:495-502. 2013
    ..With the widespread use of protease inhibitors, there was a reduction in the incidence and mortality of HIV-associated malignancies. Studies later found these drugs to have promising direct antitumor effects...
  35. pmc The contribution of malglycemia to mortality among allogeneic hematopoietic cell transplant recipients
    Marilyn J Hammer
    Department of Biobehavioral Nursing and Health Systems, University of Washington, Seattle, Washington, USA
    Biol Blood Marrow Transplant 15:344-51. 2009
    ..The applicability of these findings to other situations and whether correcting malglycemia in HCT can lead to reductions in mortality remain to be determined...
  36. pmc HIV/AIDS: epidemiology, pathophysiology, and treatment of Kaposi sarcoma-associated herpesvirus disease: Kaposi sarcoma, primary effusion lymphoma, and multicentric Castleman disease
    Ryan J Sullivan
    Division of Hematology and Oncology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Clin Infect Dis 47:1209-15. 2008
    ..The scope of this review is to present contemporary knowledge about the epidemiology, virology, and immunology of Kaposi sarcoma-associated herpesvirus and to highlight several key oncogene products that may be targets for chemotherapy...