Research Topics
| Andrew P CarterSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
Communication between the AAA+ ring and microtubule-binding domain of dyneinAndrew P Carter
Howard Hughes Medical Institute and Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94158, USA
Biochem Cell Biol 88:15-21. 2010..A recent crystal structure of dynein's MTBD sheds new light on how this long-range communication along a coiled coil might occur...
Structure and functional role of dynein's microtubule-binding domainAndrew P Carter
Howard Hughes Medical Institute and Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94158, USA
Science 322:1691-5. 2008..Surprisingly, functional data suggest that the MTBD, and not the ATPase domain, is the main determinant of the direction of dynein motility...
Force-induced bidirectional stepping of cytoplasmic dyneinArne Gennerich
The Howard Hughes Medical Institute and the Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA 94158 2200, USA
Cell 131:952-65. 2007..These results suggest a model for how dynein's two motor domains coordinate their activities during normal processive motility and provide new clues for understanding dynein-based motility in living cells...
Crystal structure of the dynein motor domainAndrew P Carter
Department of Cellular and Molecular Pharmacology, Howard Hughes Medical Institute, University of California San Francisco, 600 16th Street, San Francisco, CA 94158, USA
Science 331:1159-65. 2011..The arrangement of these elements provides clues as to how adenosine triphosphate-driven conformational changes might be transmitted across the motor domain...
Single-molecule analysis of dynein processivity and stepping behaviorSamara L Reck-Peterson
Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94158, USA
Cell 126:335-48. 2006....
The affinity of the dynein microtubule-binding domain is modulated by the conformation of its coiled-coil stalkI R Gibbons
Molecular and Cell Biology Department, University of California, Berkeley, California 94720, USA
J Biol Chem 280:23960-5. 2005....
