Research Topics
| C C CarsonSummaryAffiliation: University of North Carolina Country: USA Publications
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Detail Information
Publications
Antibiotic impregnation of inflatable penile prostheses: effect on perioperative infectionCulley Carson
University of North Carolina, Chapel Hill, NC 27599-7235, USA
Expert Rev Med Devices 1:165-7. 2004
Long-term infection outcomes after original antibiotic impregnated inflatable penile prosthesis implants: up to 7.7 years of followupCulley C Carson
Department of Urology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7235, USA
J Urol 185:614-8. 2011..Long-term data are now available on infection revision after initial implantation of antibiotic impregnated vs nonimpregnated prostheses...- Premature ejaculation: definition and prevalenceC Carson
Department of Urology, University of North Carolina, Chapel Hill, NC 27599 7235, USA
Int J Impot Res 18:S5-13. 2006..Clearly, an improved and universal definition and understanding of PE and its epidemiology will improve the clinical management of PE and the success of future epidemiologic studies and clinical trials... - Therapeutic strategies for managing erectile dysfunction: a step-care approachCulley C Carson
Division of Urology, School of Medicine, University of North Carolina at Chapel Hill, 427 Burnet Womack Bldg, Campus Box 7235, Chapel Hill, NC 27599 7235, USA
J Am Osteopath Assoc 102:S12-8. 2002..This article reviews all treatment strategies for erectile dysfunction, with a focus on PDE5 inhibitors, including novel agents that may optimize patient outcomes... - Penile prosthesis implantation: surgical implants in the era of oral medicationCulley C Carson
Division of Urology, Department of Surgery, University of North Carolina Chapel Hill, 2140 Bioinformatics Building, CB 7235, Chapel Hill, NC 27599 7235, USA
Urol Clin North Am 32:503-9, vii. 2005..Complications of these multipiece prostheses continue to decline, and patient satisfaction rates, tolerability, and longevity continue to increase... - Central nervous system-acting agents and the treatment of erectile and sexual dysfunctionCulley C Carson
Division of Urology, School of Medicine, University of North Carolina at Chapel Hill, 2140 Bioinformatics Building, Chapel Hill, NC 27599, USA
Curr Urol Rep 8:472-6. 2007..Further, development of selective dopamine receptor agonists, melatonin agonists, and other CNS stimulatory or inhibitory agents may lead to improved treatment of sexual dysfunction in men and women... - Erectile response with vardenafil in sildenafil nonresponders: a multicentre, double-blind, 12-week, flexible-dose, placebo-controlled erectile dysfunction clinical trialCulley C Carson
School of Medicine, University of North Carolina, Chapel Hill, NC 27599 7235, USA
BJU Int 94:1301-9. 2004..To evaluate the efficacy of vardenafil in patients previously unresponsive to sildenafil... - The efficacy and safety of tadalafil: an updateC C Carson
Department of Surgery, Division of Urology, University of North Carolina, Chapel Hill, NC, USA
BJU Int 93:1276-81. 2004..To provide an update on the efficacy and safety of tadalafil, a phosphodiesterase-5 inhibitor, in the treatment of erectile dysfunction (ED)... - Ejaculatory dysfunction: progress in a rarely recognized sexual problemC C Carson
University of North Carolina, Department of Urology, Chapel Hill, NC 27599-7235, USA
Int J Impot Res 18:S3-4. 2006 - Diagnosis, treatment and prevention of penile prosthesis infectionC C Carson
Division of Urology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA
Int J Impot Res 15:S139-46. 2003..Implanting urologists must be familiar prophylaxis, avoidance, and treatment of penile prosthesis infections... - Erectile dysfunction in the 21st century: whom we can treat, whom we cannot treat and patient educationC C Carson
Division of Urology, University of North Carolina, Chapel Hill, North Carolina 27599 7235, USA
Int J Impot Res 14:S29-34. 2002..If initial treatment modalities fail, more invasive alternatives or combination therapy should be offered to cure the patient's erectile dysfunction... - Penile prostheses: are they still relevant?C C Carson
Division of Urology, University of North Carolina, NC, USA
BJU Int 91:176-7. 2003 - Penile prosthesis implantation and infection for Sexual Medicine Society of North AmericaC C Carson
University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA
Int J Impot Res 13:S35-8. 2001..While penile prosthesis infection continues to be a dreaded complication, early diagnosis and aggressive surgical treatment may salvage the majority of these implants... - Oral and injectable medications for the treatment of erectile dysfunctionC C Carson
University of North Carolina, Division of Urology, 427 Burnett Womack CB 7235, Chapel Hill, NC 27599 7235, USA
Curr Urol Rep 1:307-12. 2000..We can expect these oral agents, assisted by topical and injectable agents, to successfully restore erectile function in the majority of men suffering from erectile dysfunction... - The epidemiology, anatomy, physiology, and treatment of erectile dysfunction in chronic renal failure patientsC C Carson
Department of Surgery, University of North Carolina at Chapel Hill, USA
Adv Ren Replace Ther 6:296-309. 1999..The purpose of this article is to assist the nephrology interdisciplinary team in the management of ED by reviewing possible causes, available studies, and treatment options for their patients... - Distal penile prosthesis extrusion: treatment with distal corporoplasty or Gortex windsock reinforcementC C Carson
University of North Carolina, Division of Urology, Chapel Hill 27599 7235, USA
Int J Impot Res 14:81-4. 2002..Outcomes with distal corporoplasty result in better function, less pain, and fewer recurrences than Gortex windsock repair... - A comparison of dermal and cadaveric pericardial grafts in the modified Horton-Devine procedure for Peyronie's diseaseJ L Chun
University of North Carolina, Chapel Hill, North Carolina, USA
J Urol 166:185-8. 2001..Longer followup and larger patient series are needed to confirm the advantages of cadaveric pericardium... - Physician-patient dialogue and clinical evaluation of erectile dysfunctionJ Chun
Division of Urology, University of North Carolina, Chapel Hill, North Carolina, USA
Urol Clin North Am 28:249-58, viii. 2001..The goal of evaluation is to find the appropriate treatment for the individual, dictated primarily by factors like the patients' preferences, comfort, cost, and the availability of treatment modalities... - The 'effectiveness' scale--therapeutic outcome of pharmacologic therapies for ED: an international consensus panel reportC Carson
Department of Urology, University of North Carolina, Chapel Hill, North Carolina, USA
Int J Impot Res 16:207-13. 2004..The concept of 'treatment effectiveness' is proposed as a new 'umbrella concept' or distal outcome to be evaluated... - Urinary tract infections in womenSean P McLaughlin
Division of Urology, Department of Surgery, University of North Carolina Hospitals, 2140 Bioinformatics Building, Campus Box 7235, Chapel Hill, NC 27599 7235, USA
Med Clin North Am 88:417-29. 2004..Response to therapy should govern the need for additional treatment. Certain motivated patients with three or more UTIs per year should be considered for prophylaxis therapy... - Cardiac safety in clinical trials of phosphodiesterase 5 inhibitorsCulley C Carson
University of North Carolina School of Medicine at Chapel Hill, North Carolina 27599 7235, USA
Am J Cardiol 96:37M-41M. 2005..PDE5 inhibitors are effective in treating ED, and their safety profile is excellent. There do not appear to be significant cardiovascular safety issues in the man with satisfactory cardiac and performance status... - Combination of phosphodiesterase-5 inhibitors and alpha-blockers in patients with benign prostatic hyperplasia: treatments of lower urinary tract symptoms, erectile dysfunction, or both?Culley C Carson
University of North Carolina, Chapel Hill, North Carolina, USA
BJU Int 97:39-43; discussion 44-5. 2006..Although placebo-controlled studies are needed to confirm the impact of these drugs, alone or combined, on both ED and LUTS, this reinforces the need for a common approach to managing these two highly prevalent and bothersome conditions... - PDE5 inhibitors: are there differences?Culley C Carson
Division of Urology, University of North Carolina, Chapel Hill, North Carolina 27759 7235, USA
Can J Urol 13:34-9. 2006..This discussion summarizes some of the current data on PDE5 inhibitors and their efficacy, safety, and use in other conditions... - Phase II trial of celecoxib in prostate-specific antigen recurrent prostate cancer after definitive radiation therapy or radical prostatectomyRaj S Pruthi
Division of Urologic Surgery, Department of Biostatistics, and Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
Clin Cancer Res 12:2172-7. 2006..However, human trials are absent. This study evaluated the efficacy of the COX-2 inhibitor celecoxib in prostate-specific antigen (PSA) recurrent prostate cancer after radiation therapy (X-ray therapy or XRT) or radical prostatectomy... - PNU-83757: a new agent for the treatment of erectile dysfunctionCulley C Carson
Division of Urology, University of North Carolina, Chapel Hill, 27599-7235, USA
Curr Urol Rep 3:465-6. 2002 - Carcinoma of the prostate: overview of the most common malignancy in menCulley C Carson
Division of Urology, Department of Surgery, School of Medicine, UNC, Chapel Hill 27599-7235, USA
N C Med J 67:122-7. 2006 - The efficacy of sildenafil citrate (Viagra) in clinical populations: an updateCulley C Carson
Department of Surgery, Division of Urology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7235, USA
Urology 60:12-27. 2002..Findings from published accounts of sildenafil use in the clinical practice setting further demonstrated that sildenafil is an effective treatment for a wide range of patients with ED... - Re: Long-term efficacy of sildenafil and tachyphylaxis effectCulley C Carson
J Urol 168:205. 2002 - A prospective study of the beneficial effects of dose optimization and customized instructions on patient satisfaction with sildenafil citrate (Viagra) for erectile dysfunctionAndrew R McCullough
Department of Urology, New York University School of Medicine, New York, New York 10016, USA
Urology 68:38-46. 2006..These results were enhanced with dose optimization, individual patient counseling, and customized instructions... - Cyclooxygenase-2 inhibitors and other NSAIDs in urology: current peril or future promise?Raj S Pruthi
Division of Urologic Surgery, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA
Urology 68:917-23. 2006 - Vascular risk factors for erectile dysfunctionCulley C Carson
J Urol 178:2250-1. 2007 - Phosphodiesterase type 5 inhibitors: state of the therapeutic classCulley C Carson
Division of Urology, Department of Surgery, University of North Carolina, Chapel Hill, NC, USA
Urol Clin North Am 34:507-15, vi. 2007..This discussion summarizes some of the current data on PDE5 inhibitors and their efficacy, safety, and use in other conditions... - Medical management of benign prostatic hypertrophyJeffrey W Nix
Division of Urology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC 27599 7235, USA
Can J Urol 14:53-7. 2007..PDE 5 inhibitors, while effective in relieving LUTS symptoms, have not shown effectiveness in reducing post void residual volumes or increasing urinary flow rates... - Commentary on apomorphine versus sildenafil for erectile dysfunctionCulley C Carson
J Urol 179:S95-6. 2008 - Impact of race, age, income, and residence on prostate cancer knowledge, screening behavior, and health maintenance in siblings of patients with prostate cancerRaj S Pruthi
Division of Urologic Surgery, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA
Eur Urol 50:64-9. 2006.... - Tolerance to the therapeutic effect of tadalafil does not occur during 6 months of treatment: A randomized, double-blind, placebo-controlled study in men with erectile dysfunctionChris G McMahon
Australian Centre for Sexual Health, Sydney, Australia
J Sex Med 3:504-11. 2006..Tolerance can cause a decrease in drug efficacy during chronic therapy, possibly leading to treatment failures... - Laboratory evaluation of the patient with erectile dysfunctionSean P McLaughlin
Department of Surgery, Division of Urology, University of North Carolina, Chapel Hill, NC 27599 7235, USA
Endocrine 23:113-7. 2004.... - Efficacy of antibiotic impregnation of inflatable penile prostheses in decreasing infection in original implantsCulley C Carson
University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
J Urol 171:1611-4. 2004..Infection rates in the control group were consistent with those in the published literature... - Sildenafil: a 4-year update in the treatment of 20 million erectile dysfunction patientsCulley C Carson
Division of Urology, School of Medicine, University of North Carolina at Chapel Hill, 427 Burnet Womack Bldg, Campus Box 7235, Chapel Hill, NC 27599 7235, USA
Curr Urol Rep 4:488-96. 2003..Sildenafil has been safe and effective in patients taking various medications including multiple antihypertensive drugs, selective serotonin reuptake inhibitors, cardiac, and diabetic medications... - Erectile dysfunction: evaluation and new treatment optionsCulley C Carson
Division of Urology, School of Medicine, University of North Carolina at Chapel Hill, 427 Burnet Womack Building, Campus Box 7235, Chapel Hill, NC 27599 7235, USA
Psychosom Med 66:664-71. 2004..This erectile dysfunction has substantial impact on interaction with their partners, families, and employment. ED may be a harbinger of more serious vascular events and is commonly associated with depression... - Surgical alternatives for treating Peyronie's diseaseChris K Tornehl
Division of Urology, The University of North Carolina at Chapel Hill, NC, USA
BJU Int 94:774-83. 2004 - Long-term use of sildenafilCulley C Carson
University of North Carolina School of Medicine, Chapel Hill 27599 7000, USA
Expert Opin Pharmacother 4:397-405. 2003..With the use of sildenafil, it has been clearly, clinically demonstrated that the selective inhibition of PDE5 is an appropriate, effective, safe method for the treatment of ED of all aetiologies and severities... - The efficacy, safety and tolerability of intracavernous PNU-83757 for the treatment of erectile dysfunctionRalph N Vick
Division of Urology, Department of Surgery, University of North Carolina, Chapel Hill, NC, USA
J Urol 167:2618-23. 2002..Further study is required to evaluate the efficacy of PNU-83757 combined with other drugs and with sexual stimulation... - Phosphodiesterase type 5 inhibitors for erectile dysfunctionCulley C Carson
Department of Surgery, Division of Urology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
BJU Int 96:257-80. 2005..Other PDE5Is offering further potential improvements are under active investigation... - Erectile response to vardenafil in men with a history of nonresponse to sildenafil: a time-from-dosing descriptive analysisDimitrios G Hatzichristou
Center for Sexual and Reproductive Health, Aristotle University of Thessaloniki, Thessaloniki, Greece
Clin Ther 27:1452-61. 2005..The efficacy and tolerability of vardenafil hydrochloride in men with erectile dysfunction (ED) and a history of nonresponse to sildenafil citrate have previously been reported... - Urologic manifestations of hematologic disease sickle cell, leukemia, and thromboembolic diseaseJoseph A Molitierno
Division of Urology, 428 Burnett Womack Building, CB7235, University of North Carolina Medical Center, Chapel Hill, NC 27599, USA
Urol Clin North Am 30:49-61. 2003..It is our duty to educate ourselves about these disease processes so that we can make the best clinical decisions for our patients... - Erectile dysfunction and treatment of carcinoma of the prostateCulley C Carson
Division of Urology, University of North Carolina, 2140 Bioinformatics Bldg CB 7235, Chapel Hill, NC 27599 7235, USA
Curr Urol Rep 6:461-9. 2005..Combination medical therapy and surgical penile prosthesis implantation also are options for patients who do not respond to oral PDE-5 inhibitors... - Lower urinary tract symptoms are associated with depressive symptoms in white, black and Hispanic men in the United StatesEdward O Laumann
Department of Sociology, University of Chicago, Chicago, Illinois 60637, USA
J Urol 180:233-40. 2008..The relationship between lower urinary tract symptoms and depressive symptoms was assessed using data from the Male Attitudes Regarding Sexual Health study... - Adult circumcision outcomes study: effect on erectile function, penile sensitivity, sexual activity and satisfactionKenneth S Fink
Robert Wood Johnson Clinical Scholars Program and Division of Urology, School of Medicine, and the Department of Health Behavior and Health Education, School of Public Health, University of North Carolina at Chapel Hill, USA
J Urol 167:2113-6. 2002..CONCLUSIONS: Our findings may help urologists better counsel men undergoing circumcision as adults. Prospective studies are needed to better understand the relationship between circumcision and sexual function... - Revision washout decreases implant capsule tissue culture positivity: a multicenter studyGerard D Henry
Regional Urology, Shreveport, Louisiana, USA
J Urol 179:186-90; discussion 190. 2008..We investigated a larger series of patients for positive culture rates and evaluated implant capsule tissue culture rates before and after revision washout... - Surgical treatment of Peyronie's diseaseChris Tornehl
Division of Urology, University of North Carolina Chapel Hill, 2140 Bio informatics Building, Chapel Hill, NC 27599 7235, USA
Urol Clin North Am 32:479-85, vii. 2005..This review is intended to share the experiences of other urologists in the surgical approach to PD... - Penile prosthesis cultures during revision surgery: a multicenter studyGerard D Henry
Institute for Urologic Excellence, Van Buren, Arkansas, USA
J Urol 172:153-6. 2004..To explain the higher risk in revision surgery in this prospective study we cultured clinically uninfected prostheses requiring revision. Prosthesis pain was also investigated as a predictor of positive culture... - Acute and chronic dosing of Lepidium meyenii (Maca) on male rat sexual behaviorAaron Lentz
Division of Urology, Department of Surgery, University of North Carolina, Chapel Hill, NC, USA
J Sex Med 4:332-9; discussion 339-40. 2007..For generations people of the rural community in Peru have used Lepidium meyenii Walpers (Maca), because of their belief that it improves fertility and sexual desire... - Efficacy and safety of tadalafil in men with severe erectile dysfunction in tertiary care academic centersCulley C Carson
Curr Urol Rep 6:437-8. 2005 - Revision washout decreases penile prosthesis infection in revision surgery: a multicenter studyGerard D Henry
From Regional Urology, 255 Bert Kouns Street, Shreveport, Louisiana 71196, USA
J Urol 173:89-92. 2005..During revision surgery for noninfectious reasons we investigated washing out the implant space at revision surgery and using an antibiotic coated replacement prosthesis to determine if it would decrease subsequent infection rates... - The treatment of urinary tract infections and use of ciprofloxacin extended releaseAdam D Hickerson
University of North Carolina, Division of Urology, 2140 Bioinformatics Building, Chapel Hill, NC27599 7235, USA
Expert Opin Investig Drugs 15:519-32. 2006..Economic considerations are also increasingly important and providing convenient and effective treatment leading to high clinical success decreases overall costs... - Sexual dysfunction and lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH)Raymond C Rosen
Department of Psychiatry, UMDNJ Robert Wood Johnson Medical School, 675 Hoes Lane, Piscataway, NJ 08854, USA
Eur Urol 47:824-37. 2005..For men with LUTS and sexual dysfunction, an appropriate integrated management approach, based on each patient's symptoms and outcome objectives, is warranted...