Research Topics
| Leah Y CarreonSummaryAffiliation: University of Louisville Country: USA Publications
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Detail Information
Publications
Cost-effectiveness of single-level anterior cervical discectomy and fusion five years after surgeryLeah Y Carreon
Department of Orthopaedic Surgery, Norton Leatherman Spine Center, Louisville, KY 40202, USA
Spine (Phila Pa 1976) 38:471-5. 2013..Longitudinal cohort. OBJECTIVE.: The purpose of this study is to determine the cost per quality-adjusted life year (cost/QALY) gained for single-level instrumented anterior cervical discectomy and fusion (ACDF) over 5 years...- Differentiating minimum clinically important difference for primary and revision lumbar fusion surgeriesLeah Y Carreon
Norton Leatherman Spine Center, Louisville, KY 40202, USA
J Neurosurg Spine 18:102-6. 2013..This study determined if MCID values for the Oswestry Disability Index (ODI), 36-Item Short-Form Health Survey (SF-36), and back and leg pain are different between patients undergoing primary or revision lumbar fusion... 
Clinical outcomes following repair of the pars interarticularisTravis Clegg
Department of Orthopaedic Surgery, University of Louisville School of Medicine, Kentucky, USA
Am J Orthop (Belle Mead NJ) 42:72-6. 2013..The strongest preoperative predictor of Oswestry Disability Index score was Fujii chronicity (P = .041). Motion segment sparing repair of the pars is a safe and effective procedure for refractory cases of spondylolysis...- The discriminative properties of the SF-6D compared with the SF-36 and ODILeah Y Carreon
Norton Leatherman Spine Center, Louisville, KY 40202, USA
Spine (Phila Pa 1976) 38:60-4. 2013..Longitudinal cohort... - SF-6D values stratified by specific diagnostic indicationLeah Y Carreon
Norton Leatherman Spine Center, Louisville, KY 40202, USA
Spine (Phila Pa 1976) 37:E804-8. 2012..Longitudinal cohort... - Neck Disability Index, short form-36 physical component summary, and pain scales for neck and arm pain: the minimum clinically important difference and substantial clinical benefit after cervical spine fusionLeah Y Carreon
Norton Leatherman Spine Center, 210 East Gray St, Suite 900, Louisville, KY 40202, USA
Spine J 10:469-74. 2010..The minimum clinically important difference (MCID) is a threshold of improvement that is clinically relevant to the patient. However, the true goal is to provide the patient with a substantial clinical benefit (SCB)... - Spinal appearance questionnaire: factor analysis, scoring, reliability, and validity testingLeah Y Carreon
Norton Leatherman Spine Center, Louisville, KY, USA
Spine (Phila Pa 1976) 36:E1240-4. 2011..Cross sectional... 
Predicting SF-6D utility scores from the neck disability index and numeric rating scales for neck and arm painLeah Y Carreon
Norton Leatherman Spine Center, Louisville, KY, USA
Spine (Phila Pa 1976) 36:490-4. 2011..Cross-sectional cohort...- Early versus late stabilization of spine injuries: a systematic reviewLeah Y Carreon
Norton Leatherman Spine Center, Louisville, KY 40202, USA
Spine (Phila Pa 1976) 36:E727-33. 2011..Systematic review... - Patient satisfaction after surgical correction of adolescent idiopathic scoliosisLeah Yacat Carreon
Norton Leatherman Spine Center, Louisville, KY, USA
Spine (Phila Pa 1976) 36:965-8. 2011..Longitudinal cohort... - The minimum clinically important difference in Scoliosis Research Society-22 Appearance, Activity, And Pain domains after surgical correction of adolescent idiopathic scoliosisLeah Y Carreon
Norton Leatherman Spine Center, Louisville, KY 40202, USA
Spine (Phila Pa 1976) 35:2079-83. 2010..Longitudinal cohort... - Clinical outcomes after posterolateral lumbar fusion in workers' compensation patients: a case-control studyLeah Y Carreon
Norton Leatherman Spine Center, Louisville, KY 40202, USA
Spine (Phila Pa 1976) 35:1812-7. 2010..Case-control propensity matched... - Are preoperative health-related quality of life scores predictive of clinical outcomes after lumbar fusion?Leah Y Carreon
Leatherman Spine Center, 210 East Gray Street, Louisville, KY 40202, USA
Spine (Phila Pa 1976) 34:725-30. 2009..Prospective longitudinal cohort... - Perioperative complications of recombinant human bone morphogenetic protein-2 on an absorbable collagen sponge versus iliac crest bone graft for posterior cervical arthrodesisCharles H Crawford
Department of Orthopaedic Surgery, University of Louisville School of Medicine, Louisville, KY, USA
Spine (Phila Pa 1976) 34:1390-4. 2009..Retrospective evaluation of perioperative complications with recombinant human bone morphogenetic protein-2 on an absorbable collagen sponge (rhBMP-2/ACS) versus iliac crest bone graft (ICBG) for instrumented posterior cervical fusion... - Clinical outcomes after lumbar fusion complicated by deep wound infection: a case-control studyJulio M Petilon
Norton Leatherman Spine Center, Louisville, KY 40202, USA
Spine (Phila Pa 1976) 37:1370-4. 2012..A propensity score-matched case-control study... - Sagittal alignment as a risk factor for adjacent level degeneration: a case-control studyMladen O Djurasovic
Kenton D Leatherman Spine Center and the Department of Orthopedic Surgery, University of Louisville, Louisville, KY 40202, USA
Orthopedics 31:546. 2008..Adjacent segment degeneration does not appear to be just a progression of preexisting degenerative changes at the adjacent level... - Predicting SF-6D utility scores from the Oswestry disability index and numeric rating scales for back and leg painLeah Y Carreon
Kenton D Leatherman Spine Center, Louisville, KY, USA
Spine (Phila Pa 1976) 34:2085-9. 2009..Cross-sectional cohort... - Male-female differences in Scoliosis Research Society-30 scores in adolescent idiopathic scoliosisDavid W Roberts
Department of Orthopaedic Surgery, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
Spine (Phila Pa 1976) 36:E53-9. 2011..Longitudinal cohort study... - Changes in the Oswestry Disability Index that predict improvement after lumbar fusionMladen Djurasovic
Norton Leatherman Spine Center, Louisville, Kentucky 40202, USA
J Neurosurg Spine 17:486-90. 2012..The objective of the study is to determine which clinical elements assessed by the ODI most influence improvement of overall health-related quality of life... - Health-related quality of life after posterolateral lumbar arthrodesis in patients seventy-five years of age and olderCharles H Crawford
Department of Orthopaedic Surgery, University of Louisville School of Medicine, KY, USA
Spine (Phila Pa 1976) 36:1065-8. 2011..Retrospective cohort analysis of prospectively collected data... - The perioperative cost of Infuse bone graft in posterolateral lumbar spine fusionSteven D Glassman
Department of Orthopaedic Surgery, University of Louisville School of Medicine, Louisville, KY, USA
Spine J 8:443-8. 2008..However, the relative cost of BMP remains an important concern for physicians, hospitals, and payers... - RhBMP-2 versus iliac crest bone graft for lumbar spine fusion in patients over 60 years of age: a cost-utility studyLeah Y Carreon
Kenton D Leatherman Spine Center, Louisville, KY 40202, USA
Spine (Phila Pa 1976) 34:238-43. 2009..Randomized clinical trial... - RhBMP-2 versus iliac crest bone graft for lumbar spine fusion: a randomized, controlled trial in patients over sixty years of ageSteven D Glassman
School of Medicine, University of Louisville, Louisville, KY, USA
Spine (Phila Pa 1976) 33:2843-9. 2008..Prospective randomized controlled trial of rhBMP-2/ACS (Infuse bone graft) versus iliac crest bone graft (ICBG) for lumbar spine fusion in patients over 60 years of age... - The efficacy of rhBMP-2 for posterolateral lumbar fusion in smokersSteven D Glassman
Kenton D Leatherman Spine Center, Louisville, KY, USA
Spine (Phila Pa 1976) 32:1693-8. 2007..Retrospective review of prospectively collected data, as part of an IRB-approved, FDA-regulated, randomized, nonblinded IDE trial of rhBMP-2 matrix for lumbar spinal fusion... - Predictors of complications after spinal stabilization of thoracolumbar spine injuriesJohn R Dimar
Norton Leatherman Spine Center, Louisville, KY, USA
J Trauma 69:1497-500. 2010..The purpose of this study is to identify factors predictive of a complication after surgical stabilization of thoracolumbar spine injuries... - Two-year fusion and clinical outcomes in 224 patients treated with a single-level instrumented posterolateral fusion with iliac crest bone graftJohn R Dimar
Kenton D Leatherman Spine Center, 210 East Gray Street, Suite 900, Louisville, KY 40202, USA
Spine J 9:880-5. 2009..Reported fusion rates for spine fusions using iliac crest bone graft (ICBG) vary between 40% and 100% because of different fusion techniques, patient comorbidity, diagnosis and assessment criteria... - Clinical outcomes in older patients after posterolateral lumbar fusionSteven D Glassman
Department of Orthopaedic Surgery, University of Louisville School of Medicine and the Leatherman Spine Center, 210 East Gray Street, Suite 900, Louisville, KY 40202, USA
Spine J 7:547-51. 2007.... - Perioperative complications with rhBMP-2 in transforaminal lumbar interbody fusionKirk Owens
Department of Orthopaedic Surgery, University of Louisville School of Medicine, 210 East Gray Street, Suite 1003, Louisville, KY 40202, USA
Eur Spine J 20:612-7. 2011..It will be necessary to weigh this incidence of complications against the complication rate associated with ICBG harvest and any differential benefit in obtaining a solid arthrodesis... - Defining substantial clinical benefit following lumbar spine arthrodesisSteven D Glassman
Kenton D Leatherman Spine Center, 210 East Gray Street, Suite 900, Louisville, KY 40202, USA
J Bone Joint Surg Am 90:1839-47. 2008..Therefore, we sought to define thresholds of substantial clinical benefit for commonly used health-related quality-of-life measures following lumbar spine arthrodesis... - Diagnostic accuracy and reliability of fine-cut CT scans with reconstructions to determine the status of an instrumented posterolateral fusion with surgical exploration as reference standardLeah Y Carreon
Kenton D Leatherman Spine Center, Louisville, KY 40202, USA
Spine (Phila Pa 1976) 32:892-5. 2007..Accuracy of a diagnostic test referenced to the gold standard... - Adverse events in patients re-exposed to bone morphogenetic protein for spine surgeryLeah Y Carreon
Kenton D Leatherman Spine Center, 210 East Gray Street, Suite 900, Louisville, KY 40202, USA
Spine (Phila Pa 1976) 33:391-3. 2008..Case series from a single spine specialty clinic... - Instrumented open-door laminoplasty as treatment for cervical myelopathy in 104 patientsJohn R Dimar
Department of Orthopaedic Surgery, University of Louisville School of Medicine, Louisville, KY 40202, USA
Am J Orthop (Belle Mead NJ) 38:E123-8. 2009..Open-door laminoplasty with miniplate instrumentation is an effective, safe method for preventing progression of myelopathy with multilevel involvement while alleviating the need for multilevel fusion... - Clinical and radiographic analysis of an optimized rhBMP-2 formulation as an autograft replacement in posterolateral lumbar spine arthrodesisJohn R Dimar
Leatherman Spine Center, 210 East Gray Street, Suite 900, Louisville, KY 40202, USA
J Bone Joint Surg Am 91:1377-86. 2009.... - Lumbar degenerative classification studySteven D Glassman
Department of Orthopaedic Surgery, University of Louisville School of Medicine, Louisville, Kentucky, USA
Am J Orthop (Belle Mead NJ) 35:175-9; discussion 179. 2006..For this reason, an ongoing effort to refine nomenclature and classification is necessary... - Lumbar lordosis restoration following single-level instrumented fusion comparing 4 commonly used techniquesJohn R Dimar
Norton Leatherman Spine Center, Louisville, Kentucky, USA
Orthopedics 34:e760-4. 2011..Maintenance of lordosis and anterior and posterior disk space height is significantly better with anterior interbody fusion with LT cages... - Lumbar fusion outcomes stratified by specific diagnostic indicationSteven D Glassman
Department of Orthopaedic Surgery, University of Louisville School of Medicine, Louisville, KY 40202, USA
Spine J 9:13-21. 2009..Diagnostic specificity beyond the symptom of low back pain or the presence of lumbar degeneration needs to be delineated such that outcomes data can be effectively translated into clinical decision making or evidence-based guidelines... - Initial fusion rates with recombinant human bone morphogenetic protein-2/compression resistant matrix and a hydroxyapatite and tricalcium phosphate/collagen carrier in posterolateral spinal fusionSteven D Glassman
Department of Orthopaedic Surgery, University of Louisville School of Medicine, The Kenton D Leatherman Spine Center, Louisville, Kentucky, USA
Spine (Phila Pa 1976) 30:1694-8. 2005..Prospective, randomized, unblinded study of iliac crest bone graft (ICBG) versus recombinant human bone morphogenetic protein-2/compression resistant matrix (rhBMP-2/CRM)in a posterolateral instrumented fusion procedure... - The effect of obesity on clinical outcomes after lumbar fusionMladen Djurasovic
Kenton D Leatherman Spine Center, University of Louisville School of Medicine, Louisville, KY 40202, USA
Spine (Phila Pa 1976) 33:1789-92. 2008..Retrospective cohort analysis... - Health-related quality of life improvements in patients undergoing lumbar spinal fusion as a revision surgeryMladen Djurasovic
Norton Leatherman Center, Louisville, KY, USA
Spine (Phila Pa 1976) 36:269-76. 2011..Retrospective cohort analysis... - The costs and benefits of nonoperative management for adult scoliosisSteven D Glassman
Department of Orthopaedic Surgery, University of Louisville School of Medicine, Louisville, KY 40202, USA
Spine (Phila Pa 1976) 35:578-82. 2010..A prospective cohort of adult scoliosis patients treated nonoperatively had a minimum of 2-year follow-up during which time data were collected on the type and quantity of nonoperative treatment used... - The cost effectiveness of single-level instrumented posterolateral lumbar fusion at 5 years after surgerySteven D Glassman
Norton Leatherman Spine Center, Louisville, KY 40202, USA
Spine (Phila Pa 1976) 37:769-74. 2012..Cost effectiveness analysis for single-level instrumented fusion during a 5-year postoperative interval... - Contemporary management of symptomatic lumbar spinal stenosisMladen Djurasovic
Norton Leatherman Spine Center, 210 East Gray Street, Suite 900, Louisville, KY 40202, USA
Orthop Clin North Am 41:183-91. 2010..The Spine Patient Outcomes Research Trial, a study that evaluates the common surgical treatments for the lumbar spine, has addressed this deficiency and is discussed in this article... - Identification and surgical treatment of primary thoracic spinal stenosisJohn R Dimar
Department of Orthopaedic Surgery, University of Louisville School of Medicine, Louisville, KY, USA
Am J Orthop (Belle Mead NJ) 37:564-8. 2008..Expedient wide decompression with concurrent instrumented fusion is recommended to prevent late development of spinal instability and recurrent spinal stenosis... - Clinical outcomes and fusion success at 2 years of single-level instrumented posterolateral fusions with recombinant human bone morphogenetic protein-2/compression resistant matrix versus iliac crest bone graftJohn R Dimar
Kenton D Leatherman Spine Center, Louisville, KY, USA
Spine (Phila Pa 1976) 31:2534-9; discussion 2540. 2006..A higher recombinant human bone morphogenetic protein (rhBMP)-2 dose and a carrier specific for posterior spine applications were used... - Reliability and accuracy of fine-cut computed tomography scans to determine the status of anterior interbody fusions with metallic cagesLeah Y Carreon
Kenton D Leatherman Spine Center, 210 East Gray Street, Suite 900, Louisville, KY 40202, USA
Spine J 8:998-1002. 2008..Computed tomography (CT) scan has been shown to be more accurate than radiographs in evaluating anterior interbody fusion but may still over-read the extent of fusion... - Posterior iliac crest pain after posterolateral fusion with or without iliac crest graft harvestJennifer M Howard
University of Louisville School of Medicine, 323 E Chestnut St, Louisville, KY 40292, USA
Spine J 11:534-7. 2011..Considerable debate exists regarding the incidence of persistent pain from the iliac crest bone graft (ICBG) harvest site. Different study designs have led to a variety of reported rates... - Predicting health-utility scores from the Cervical Spine Outcomes Questionnaire in a multicenter nationwide study of anterior cervical spine surgeryRichard L Skolasky
Department of Orthopaedic Surgery, The Johns Hopkins University, Baltimore, MD, USA
Spine (Phila Pa 1976) 36:2211-6. 2011..Cross-sectional analysis of the Cervical Spine Research Society Outcomes Study, a longitudinal multicenter cohort study... - The influence of preoperative MRI findings on lumbar fusion clinical outcomesMladen Djurasovic
Norton Leatherman Spine Center, Louisville, KY 40202, USA
Eur Spine J 21:1616-23. 2012..The purpose of this study is to investigate which MRI findings in patients with degenerative disc disease predict clinical improvement with lumbar fusion... - Complications with recombinant human bone morphogenetic protein-2 in posterolateral spine fusion associated with a dural tearSteven D Glassman
Norton Leatherman Spine Center, 210 East Gray St, Suite 900, Louisville, KY 40202, USA
Spine J 11:522-6. 2011..quot; Although this study was conducted at the spinal cord level, the observation generates obvious concerns for the much more common scenario of a dural tear associated with lumbar decompression and fusion... - Complications and concerns with osteobiologics for spine fusion in clinical practiceSteven D Glassman
Department of Orthopaedic Surgery, University of Louisville School of Medicine, Louisville, KY, USA
Spine (Phila Pa 1976) 35:1621-8. 2010..Literature-based topic review... - Lumbar fusion outcomes in patients with rheumatoid arthritisCharles H Crawford
Department of Orthopaedic Surgery, University of Louisville School of Medicine, 210 East Gray Street, Suite 1003, Louisville, KY 40202, USA
Eur Spine J 17:822-5. 2008..692). Surgeons and their RA patients who undergo an instrumented lumbar fusion can expect a slightly higher complication rate than patients without RA which may be related to osteopenia and immunosuppression... - Correlation between cervical spine sagittal alignment and clinical outcome after anterior cervical discectomy and fusionJeffrey L Gum
Department of Orthopaedic Surgery, University of Louisville School of Medicine, Louisville, Kentucky, USA
Am J Orthop (Belle Mead NJ) 41:E81-4. 2012..This suggests that maintenance or restoration of overall cervical lordosis is important in achieving a successful result after ACDF... - A diagnostic classification for lumbar spine registry developmentSteven D Glassman
Norton Leatherman Spine Center, 210 East Gray St, Louisville, KY 40202, USA
Spine J 11:1108-16. 2011..To design a lumbar spine registry such that the accumulated data provide applicable guidance for clinical treatment, the incorporation of a functional diagnostic matrix is critical... - Traumatic pediatric pneumorachis: case report and review of the literatureJohn R Dimar
Norton Leatherman Spine Center, Louisville, KY 40202, USA
Spine (Phila Pa 1976) 35:E860-3. 2010..Case report... - Treatment of pyogenic vertebral osteomyelitis with anterior debridement and fusion followed by delayed posterior spinal fusionJohn R Dimar
Leatherman Spine Center, Louisville, Kentucky, USA
Spine (Phila Pa 1976) 29:326-32; discussion 332. 2004..Case series... - Blood salvage produces higher total blood product costs in single-level lumbar spine surgeryChelsea E Canan
Norton Leatherman Spine Center, Louisville, KY and University of Louisville School of Public Health and Information Sciences, Louisville, KY
Spine (Phila Pa 1976) 38:703-8. 2013..Further studies are needed to evaluate the necessity for cell saver among other types of spinal surgery... - Perioperative complications of posterior lumbar decompression and arthrodesis in older adultsLeah Y Carreon
Norton Hospital, Louisville, Kentucky, USA
J Bone Joint Surg Am 85:2089-92. 2003..In this study, we examined the rates of perioperative complications associated with posterior lumbar decompression and arthrodesis in patients sixty-five years of age or older... - Early versus late stabilization of the spine in the polytrauma patientJohn R Dimar
Norton Leatherman Spine Center, Louisville, KY 40202, USA
Spine (Phila Pa 1976) 35:S187-92. 2010..Systematic review... - A prospective analysis of intraoperative electromyographic monitoring of posterior cervical screw fixationMladen Djurasovic
Leatherman Spine Center, Louisville, KY 40202, USA
J Spinal Disord Tech 18:515-8. 2005..Values below 10 mA are associated with screw malposition and warrant exploration, repositioning, and possible removal... - Fusion and nonsurgical treatment for symptomatic lumbar degenerative disease: a systematic review of Oswestry Disability Index and MOS Short Form-36 outcomesLeah Y Carreon
Leatherman Spine Center, Louisville, KY 40202, USA
Spine J 8:747-55. 2008..Definite conclusions are difficult to draw because of differences in patient inclusion criteria, fusion technique, nonoperative treatment regimen, and clinical outcome measures used to determine success... - Surgical management of severely displaced pediatric seat-belt fracture-dislocations of the lumbar spine associated with occlusion of the abdominal aorta and avulsion of the cauda equina: a report of two casesCharles H Crawford
University of Louisville Department of Orthopaedic Surgery, Louisville, KY, USA
Spine (Phila Pa 1976) 33:E325-8. 2008..Case report... - Non-neurologic complications following surgery for adolescent idiopathic scoliosisLeah Y Carreon
Leatherman Spine Center, 210 East Gray Street, Suite 900, Louisville, KY 40202, USA
J Bone Joint Surg Am 89:2427-32. 2007..The purpose of this study was to determine the prevalence of non-neurologic complications following surgery for adolescent idiopathic scoliosis and to identify preoperative and operative factors that can increase this risk... - Juvenile degenerative disc disease: a report of 76 cases identified by magnetic resonance imagingJohn R Dimar
Kenton D Leatherman Spine Center, University of Louisville School of Medicine, Louisville, KY 40202, USA
Spine J 7:332-7. 2007..This assumption may be incorrect because patients in this population may have underlying juvenile degenerative disc disease (JDDD), an important pathological diagnosis in the adult population... - Motion segment-sparing repair of symptomatic chronic pars defectsIan S Mutchnick
Department of Neurosurgery, Norton Neuroscience Institute, Louisville, Kentucky, USA
J Neurosurg Spine 15:159-63. 2011..Since many patients with SP undergoing operative repair are young, a procedure with the lowest biomechanical profile is desirable, and direct pars repair is recommended. The authors here explore the limits of direct pars repair... - Use of cervical collar after single-level anterior cervical fusion with plate: is it necessary?Mitchell J Campbell
Leatherman Spine Center, 210 East Gray Street, Louisville, KY 40202, USA
Spine (Phila Pa 1976) 34:43-8. 2009..Randomized clinical trial... - Intra- and inter-observer reliability of determining radiographic sagittal parameters of the spine and pelvis using a manual and a computer-assisted methodsJohn R Dimar
Leatherman Spine Center, 210 East Gray Street, Suite 900, Louisville, KY 40202, USA
Eur Spine J 17:1373-9. 2008.... - Long fusions to the sacrum in elderly patients with spinal deformityCharles H Crawford
Norton Leatherman Spine Center, 210 East Gray Street, Suite 900, Louisville, KY 40202, USA
Eur Spine J 21:2165-9. 2012..This study evaluated clinical outcomes in elderly (>65) adult deformity patients who underwent posterior instrumented reconstruction consisting of fusion from the thoracic spine to the sacrum with iliac fixation... - Reliability and agreement between fine-cut CT scans and plain radiography in the evaluation of posterolateral fusionsLeah Y Carreon
Leatherman Spine Center, 210 East Gray Street, Suite 900, Louisville, KY 40202, USA
Spine J 7:39-43. 2007..Previous studies evaluated CT scans using 2-4-mm thick slices with limited reconstructions... - Pediatric spine fractures: a review of 137 hospital admissionsLeah Y Carreon
Leatherman Spine Center, Louisville, Kentucky 40202, USA
J Spinal Disord Tech 17:477-82. 2004..A retrospective clinical case series was conducted to present data from a large series of pediatric patients with spine injuries from a single regional trauma center... - Correlation of spinal canal dimensions to efficacy of epidural steroid injection in spinal stenosisMitchell J Campbell
Department of Orthopaedic Surgery, University of Louisville School of Medicine, Louisville, Kentucky, USA
J Spinal Disord Tech 20:168-71. 2007..To determine a critical canal dimension in patients with spinal stenosis that predicts response to epidural steroid injections (ESI)...