Jean K Carr
Affiliation: University of Maryland
- HIV-1 recombinants with multiple parental strains in low-prevalence, remote regions of Cameroon: evolutionary relics?Jean K Carr
Institute of Human Virology, Univ, of Maryland School of Medicine, Baltimore, MD, USA
Retrovirology 7:39. 2010..Partial pol amplicons (N = 164) and nearly full virus genomes (N = 78) were sequenced. Among the 3956 rural villagers studied, the prevalence of HIV infection was 4.9%; among the hospitalized and clinic patients, it was 8.6%...
- HIV-1 epidemic in the Caribbean is dominated by subtype BYuka Nadai
Institute of Human Virology, School of Medicine, University of Maryland, Baltimore, Maryland, United States of America
PLoS ONE 4:e4814. 2009..To expand our knowledge of this, nearly full genome amplification, sequencing and analysis was conducted...
- Protocol for nearly full-length sequencing of HIV-1 RNA from plasmaYuka Nadai
Department of Epidemiology, Institute of Human Virology, University of Maryland, Baltimore, Maryland, USA
PLoS ONE 3:e1420. 2008..This protocol provides a useful tool for molecular analysis to understand the HIV epidemic and pathogenesis, as well as diagnosis, therapy and future vaccine strategies...
- Emergence of unique primate T-lymphotropic viruses among central African bushmeat huntersNathan D Wolfe
Department of Epidemiology, Bloomberg School of Public Health, The Johns Hopkins University, Baltimore, MD 21205, USA
Proc Natl Acad Sci U S A 102:7994-9. 2005....
- Exposure to nonhuman primates in rural CameroonNathan D Wolfe
Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
Emerg Infect Dis 10:2094-9. 2004..The study demonstrates that exposure is not limited to small groups of hunters. A high percentage of rural villagers report exposure to nonhuman primate blood and body fluids and risk acquiring infectious diseases...
- Simian T-lymphotropic virus diversity among nonhuman primates, CameroonDavid M Sintasath
Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
Emerg Infect Dis 15:175-84. 2009..Broad screening using this relatively easy collection strategy has potential for large-scale monitoring of retrovirus cross-species transmission among highly exposed human populations...
- Two independent epidemics of HIV in MarylandJean K Carr
Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA
J Acquir Immune Defic Syndr 54:297-303. 2010....
- Characterization of the emerging HIV type 1 and HCV epidemics among injecting drug users in Dushanbe, TajikistanChris Beyrer
Johns Hopkins Bloomberg School of Public Health, Department of Epidemiology, Baltimore, Maryland 21205, USA
AIDS Res Hum Retroviruses 25:853-60. 2009..Targeted prevention programs offering both needle exchange programs and opiate substitution therapies are urgently called for to prevent the further spread of HIV and HCV in Tajikistan...
- Genetic characterization of HIV-1 strains circulating in KazakhstanLindsay M Eyzaguirre
US Military HIV Research Program, Walter Reed Army Institute of Research, and the Henry M Jackson Foundation for the Advancement of Military Medicine, Rockville, MD, USA
J Acquir Immune Defic Syndr 46:19-23. 2007..The HIV epidemic in Kazakhstan is predominantly in IDUs and is indigenous to the geographic region, and most of the strains are genetically similar to those circulating in the FSU and other parts of Central Asia...
- Elevated hypermutation levels in HIV-1 natural viral suppressorsLindsay M Eyzaguirre
Institute of Human Virology, University of Maryland School of Medicine, Baltimore, United States 725 West Lombard Street Baltimore, MD 21201, USA
Virology 443:306-12. 2013..043). Our data suggests that inactivation of the virus through the APOBEC3G system may contribute to the NVS phenotype...
- Tenofovir-based regimens associated with less drug resistance in HIV-1-infected Nigerians failing first-line antiretroviral therapyMary Ann A Etiebet
Institute of Human Virology, University of Maryland School of Medicine, MD, USA
AIDS 27:553-61. 2013..We retrospectively conducted genotypic analysis on archived samples from Nigerian patients who received targeted viral load testing to confirm treatment failure and report their drug resistance mutation patterns...
- Identification of new CRF51_01B in Singapore using full genome analysis of three HIV type 1 isolatesOon Tek Ng
Johns Hopkins School of Medicine, Johns Hopkins Medical Institution, Baltimore, MD, USA
AIDS Res Hum Retroviruses 28:527-30. 2012..As the three patients were not epidemiologically linked, this recombinant form has been designated CRF51_01B. Identification of the novel recombinant forms indicates ongoing active HIV-1 transmission in Singapore...
- Characterization of acute HIV-1 infection in high-risk Nigerian populationsMan Charurat
Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD, USA
J Infect Dis 205:1239-47. 2012..Acute phase of human immunodeficiency virus (HIV) infection (AHI) may account for a significant proportion of HIV-1 transmission. We identified and characterized individuals in Nigeria with AHI...
- Genetic variation in vitro and in vivo of an attenuated Lassa vaccine candidateJuan C Zapata
Institute of Human Virology, University of Maryland School of Medicine, Baltimore, Maryland, USA
J Virol 88:3058-66. 2014..In conclusion, the preclinical studies of ML29 as a Lassa virus vaccine candidate have been advanced, showing high levels of protection in nonhuman primates and acceptable stability both in vitro and in vivo. ..
- Naturally acquired simian retrovirus infections in central African huntersNathan D Wolfe
Department of Epidemiology Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
Lancet 363:932-7. 2004..We investigated zoonotic infection in individuals living in central Africa...