D O Carpenter

Summary

Affiliation: University at Albany
Country: USA

Publications

  1. pmc Increased rate of hospitalization for diabetes and residential proximity of hazardous waste sites
    Maria Kouznetsova
    Department of Epidemiology and Biostatistics, School of Public Health, University at Albany, Rensselaer, New York 12144 3429, USA
    Environ Health Perspect 115:75-9. 2007
  2. pmc Diabetes in relation to serum levels of polychlorinated biphenyls and chlorinated pesticides in adult Native Americans
    Neculai Codru
    Department of Epidemiology and Statistics, School of Public Health, University at Albany, Rensselaer, New York 12144 3429, USA
    Environ Health Perspect 115:1442-7. 2007
  3. pmc Blood lead and IQ in older children
    David O Carpenter
    Environ Health Perspect 113:A581-2. 2005
  4. pmc Lower serum testosterone associated with elevated polychlorinated biphenyl concentrations in Native American men
    Alexey Goncharov
    Department of Environmental Health Sciences, University at Albany, 5 University Place, Rensselaer, NY 12144, USA
    Environ Health Perspect 117:1454-60. 2009
  5. pmc Increase in metabolic syndrome-related hospitalizations in relation to environmental sources of persistent organic pollutants
    Alexander V Sergeev
    Department of Social and Public Health, Ohio University, Grover Center W343, Athens, OH 45701, USA
    Int J Environ Res Public Health 8:762-76. 2011
  6. pmc Association between residential proximity to PERC dry cleaning establishments and kidney cancer in New York City
    Jing Ma
    Department of Epidemiology and Biostatistics, University at Albany School of Public Health, Rensselaer, NY 12144, USA
    J Environ Public Health 2009:183920. 2009
  7. pmc Levels of polychlorinated biphenyls (PCBs) and three organochlorine pesticides in fish from the Aleutian Islands of Alaska
    Sara Hardell
    Faculty of Health Sciences, Linkoping University, Linkoping, Sweden
    PLoS ONE 5:e12396. 2010
  8. pmc Cytotoxicity of environmentally relevant concentrations of aluminum in murine thymocytes and lymphocytes
    Jamal Kamalov
    School of Public Health, University at Albany, Rensselaer, NY 12144, USA
    J Toxicol 2011:796719. 2011
  9. pmc Blood pressure in relation to concentrations of PCB congeners and chlorinated pesticides
    Alexey Goncharov
    Department of Environmental Health Sciences, School of Public Health, University at Albany, Rensselaer, New York, USA
    Environ Health Perspect 119:319-25. 2011
  10. pmc Childhood asthma and indoor allergens in Native Americans in New York
    Simona Surdu
    Department of Epidemiology and Biostatistics, School of Public Health, University at Albany, SUNY, One University Place, Room 127, Rensselaer NY, 12144 3445, USA
    Environ Health 5:22. 2006

Research Grants

  1. Effects of Dioxin on Vietnamese Civilians
    David Carpenter; Fiscal Year: 2004

Collaborators

Detail Information

Publications77

  1. pmc Increased rate of hospitalization for diabetes and residential proximity of hazardous waste sites
    Maria Kouznetsova
    Department of Epidemiology and Biostatistics, School of Public Health, University at Albany, Rensselaer, New York 12144 3429, USA
    Environ Health Perspect 115:75-9. 2007
    ..Epidemiologic studies suggest that there may be an association between environmental exposure to persistent organic pollutants (POPs) and diabetes...
  2. pmc Diabetes in relation to serum levels of polychlorinated biphenyls and chlorinated pesticides in adult Native Americans
    Neculai Codru
    Department of Epidemiology and Statistics, School of Public Health, University at Albany, Rensselaer, New York 12144 3429, USA
    Environ Health Perspect 115:1442-7. 2007
    ..Recent research suggests that diabetes, a condition whose incidence is increasing, is associated with exposure to polychlorinated biphenyls (PCBs) and chlorinated pesticides...
  3. pmc Blood lead and IQ in older children
    David O Carpenter
    Environ Health Perspect 113:A581-2. 2005
  4. pmc Lower serum testosterone associated with elevated polychlorinated biphenyl concentrations in Native American men
    Alexey Goncharov
    Department of Environmental Health Sciences, University at Albany, 5 University Place, Rensselaer, NY 12144, USA
    Environ Health Perspect 117:1454-60. 2009
    ..Polychlorinated biphenyls (PCBs) and chlorinated pesticides are endocrine disruptors, altering both thyroid and estrogen hormonal systems. Less is known of action on androgenic systems...
  5. pmc Increase in metabolic syndrome-related hospitalizations in relation to environmental sources of persistent organic pollutants
    Alexander V Sergeev
    Department of Social and Public Health, Ohio University, Grover Center W343, Athens, OH 45701, USA
    Int J Environ Res Public Health 8:762-76. 2011
    ..001). Our findings contribute to the body of evidence supporting the hypothesis of POP constituting an environmental risk factor for the MetS. Further studies investigating exposure to POP and insulin resistance are warranted...
  6. pmc Association between residential proximity to PERC dry cleaning establishments and kidney cancer in New York City
    Jing Ma
    Department of Epidemiology and Biostatistics, University at Albany School of Public Health, Rensselaer, NY 12144, USA
    J Environ Public Health 2009:183920. 2009
    ..To our knowledge, this study is the first to demonstrate an association between residential PERC exposure and cancer risk...
  7. pmc Levels of polychlorinated biphenyls (PCBs) and three organochlorine pesticides in fish from the Aleutian Islands of Alaska
    Sara Hardell
    Faculty of Health Sciences, Linkoping University, Linkoping, Sweden
    PLoS ONE 5:e12396. 2010
    ..These contaminants therefore may pose a risk to Alaska Natives that follow a traditional diet high in marine mammals and fish, in which POPs bioaccumulate...
  8. pmc Cytotoxicity of environmentally relevant concentrations of aluminum in murine thymocytes and lymphocytes
    Jamal Kamalov
    School of Public Health, University at Albany, Rensselaer, NY 12144, USA
    J Toxicol 2011:796719. 2011
    ..Injury only rarely proceeded to rapid cell death and was associated with cell swelling. These results suggest that aluminum has cytotoxic effects on cells of the immune system...
  9. pmc Blood pressure in relation to concentrations of PCB congeners and chlorinated pesticides
    Alexey Goncharov
    Department of Environmental Health Sciences, School of Public Health, University at Albany, Rensselaer, New York, USA
    Environ Health Perspect 119:319-25. 2011
    ..Residents of Anniston, Alabama, live near a Monsanto plant that manufactured polychlorinated biphenyls (PCBs) from 1929 to 1971 and are relatively heavily exposed...
  10. pmc Childhood asthma and indoor allergens in Native Americans in New York
    Simona Surdu
    Department of Epidemiology and Biostatistics, School of Public Health, University at Albany, SUNY, One University Place, Room 127, Rensselaer NY, 12144 3445, USA
    Environ Health 5:22. 2006
    ..The objective of this study was to assess the correlation between childhood asthma and potential risk factors, especially exposure to indoor allergens, in a Native American population...
  11. pmc Hazardous waste sites and stroke in New York State
    Ivan Shcherbatykh
    Department of Environmental Health and Toxicology, School of Public Health, University at Albany, SUNY, One University Place, Rensselaer, NY 12144, USA
    Environ Health 4:18. 2005
    ..We tested the hypothesis that exposure to contaminants from residence near hazardous waste sites in New York State influences the occurrence of stroke...
  12. ncbi request reprint Setting prudent public health policy for electromagnetic field exposures
    David O Carpenter
    Institute for Health and the Environment, University at Albany, Rensselaer, NY 12144, USA
    Rev Environ Health 23:91-117. 2008
    ....
  13. ncbi request reprint Environmental contaminants as risk factors for developing diabetes
    David O Carpenter
    Institute for Health and the Environment, University at Albany, Rensselaer, NY 12144, USA
    Rev Environ Health 23:59-74. 2008
    ..Because diabetes is a dangerous disease that is increasing in frequency throughout the world, further study of the possibility that exposure to POPs contributes to the etiology of diabetes is critical...
  14. ncbi request reprint Children's environmental health in Central Asia and the Middle east
    David O Carpenter
    Institute for Health and the Environment, University at Albany SUNY, Rensselaer, New York 12144 3429, USA
    Int J Occup Environ Health 12:362-8. 2006
    ....
  15. ncbi request reprint Polychlorinated biphenyls (PCBs): routes of exposure and effects on human health
    David O Carpenter
    Institute for Health and the Environment University at Albany, SUNY, USA
    Rev Environ Health 21:1-23. 2006
    ..As knowledge of their toxic effects has grown faster than environmental levels have declined, PCBs remain dangerous contaminants...
  16. ncbi request reprint The importance of the Great Lakes Water Quality Agreement
    David O Carpenter
    Institute for Health and the Environment, University at Albany, Renssselaer, NY 12144, USA
    J Public Health Policy 28:216-20. 2007
  17. ncbi request reprint Polychlorinated biphenyls in serum of the Siberian Yupik people from St. Lawrence Island, Alaska
    David O Carpenter
    Institute for Health and the Environment, University at Albany, Rensselaer, New York 12144, USA
    Int J Circumpolar Health 64:322-35. 2005
    ..To determine serum levels of polychlorinated biphenyls (PCBs) in Siberian Yupik adults from St. Lawrence Island, Alaska, and to determine the relative contribution of atmospheric transport of PCBs and local contamination to body burdens...
  18. ncbi request reprint Health effects of persistent organic pollutants: the challenge for the Pacific Basin and for the world
    David O Carpenter
    Institute for Health and the Environment, University of Albany, Rensselaer, NY 12144, USA
    Rev Environ Health 26:61-9. 2011
    ..Others are still manufactured and used. These are dangerous chemicals that have contaminated even areas remote from the industrialized world, such as the polar regions...
  19. doi request reprint Asthma and infectious respiratory disease in relation to residence near hazardous waste sites
    David O Carpenter
    Institute for Health and the Environment, University at Albany, Rensselaer, New York, USA
    Ann N Y Acad Sci 1140:201-8. 2008
    ..These observations are consistent with the hypothesis that simply living near a hazardous waste site increases risk of exposure to substances that contribute to respiratory disease...
  20. doi request reprint Environmental causes of violence
    David O Carpenter
    Institute for Health and the Environment, University at Albany, Rensselaer, NY 12144, USA
    Physiol Behav 99:260-8. 2010
    ..If this pattern is true for lead and other contaminants, the most effective way to fight crime may be to prevent exposure to these contaminants...
  21. pmc Incidence of endocrine disease among residents of New York areas of concern
    D O Carpenter
    Department of Environmental Health and Toxicology, University at Albany, Rensselaer, New York 12144, USA
    Environ Health Perspect 109:845-51. 2001
    ..Although many factors influence incidence of thyroid and genital diseases, our results are consistent with the hypothesis that exposure to environmental contaminants through residence near polluted sites may be a factor...
  22. pmc Electrophysiologic and behavioral effects of perinatal and acute exposure of rats to lead and polychlorinated biphenyls
    David O Carpenter
    School of Public Health, University at Albany, One University Place B242, Rensselaer, NY 12144 3456, USA
    Environ Health Perspect 110:377-86. 2002
    ..These results demonstrate that lead and PCBs have similar effects on synaptic plasticity and behavior and suggest that the compounds may act through a common mechanism...
  23. ncbi request reprint Intracellular activity of rat spinal cord motoneurons in slices
    N Hori
    School of Public Health, University at Albany, One University Place, Rm. B242, Rensselaer, NY 12144-3456, USA
    J Neurosci Methods 112:185-91. 2001
    ..The apparent lack of desensitization of AMPA responses, usually seen in other neurons, may underlie the unique vulnerability of motoneurons to excitotoxic damage...
  24. ncbi request reprint Effects of acetylcholine and GABA on neurons in the area postrema of Suncus murinus brainstem slices
    N L Strominger
    School of Public Health, University at Albany, Rensselaer, NY 12214, USA
    Neurosci Lett 309:77-80. 2001
    ..Bath perfusion of curare, but not atropine, inhibited the response. Ionophoresis of GABA caused strong inhibition. The data show Suncus AP contains neurons that are sensitive to nicotine and GABA and may be emetogenic...
  25. pmc High serum PCBs are associated with elevation of serum lipids and cardiovascular disease in a Native American population
    Alexey Goncharov
    Institute for Health and the Environment, University at Albany, 5 University Place, A217, Rensselaer, NY 12144 3429, USA
    Environ Res 106:226-39. 2008
    ....
  26. ncbi request reprint Chronic diseases surveillance of St. Regis Mohawk Health Service patients
    S Negoita
    School of Public Health, University at Albany in Rensselaer, New York, USA
    J Public Health Manag Pract 7:84-91. 2001
    ..Morbidity from asthma and acquired hypothyroidism should be monitored in the future and investigated through analytic epidemiologic methods for a possible association with lifestyle and environmental factors...
  27. ncbi request reprint Electrophysiological effects of three groups of glutamate metabotropic receptors in rat piriform cortex
    Y Tan
    Department of Environmental Health Sciences, School of Public Health, and Institute for Health and the Environment, University at Albany, Five University Place, A 217, Rensselaer, NY 12144, USA
    Cell Mol Neurobiol 26:915-24. 2006
    ..Groups I and II are equally potent in the LOT and association fiber pathways, while group III receptors are more potent in the LOT than the association fiber pathways...
  28. ncbi request reprint Development of synaptic responses and plasticity at the SC-CA1 and MF-CA3 synapses in rat hippocampus
    R J Hussain
    Department of Environmental Health and Toxicology, School of Public Health, University at Albany, Rensselaer, New York 12144, USA
    Cell Mol Neurobiol 21:357-68. 2001
    ..In CA3, but not CA1, LTP at P60 was less than at P30. 4. PTP did not show clear alterations with age in either region. PPF decreased with age in CA1 but not CA3...
  29. ncbi request reprint Differential actions and excitotoxicity of glutamate agonists on motoneurons in adult mouse cervical spinal cord slices
    N Hori
    Department of Environmental Health, School of Public Health, University at Albany, 1 University Place, Rm B242, Rensselaer, NY 12144 3456, USA
    Brain Res 958:434-8. 2002
    ..Our results indicate that adult motoneurons have few or no NMDA receptors...
  30. ncbi request reprint Effects of metals on the nervous system of humans and animals
    D O Carpenter
    School of Public Health University at Albany Rensselaer, NY 12144, USA
    Int J Occup Med Environ Health 14:209-18. 2001
    ..Other metals, especially lead, mercury, manganese and copper, have been implicated in amvotrophic lateral sclerosis and Parkinson's disease...
  31. ncbi request reprint Effects of melatonin on synaptic transmission and long-term potentiation in two areas of mouse hippocampus
    Mete Ozcan
    Institute for Health and Environment, University at Albany, 5 University Place, Rensselaer, NY 12144 3429, USA
    Brain Res 1111:90-4. 2006
    ..1 nor 1 mM melatonin altered the fEPSP, whereas both concentrations only slightly reduced LTP. These results demonstrate that melatonin significantly alters synaptic transmission and LTP in the CA1 but has only modest actions in CA3...
  32. pmc Understanding the human health effects of chemical mixtures
    David O Carpenter
    School of Public Health, Department of Environmental Health and Toxiciology, University at Albany, State University of New York, Rensselaer 12144, USA
    Environ Health Perspect 110:25-42. 2002
    ..We present results of selected cellular and animal studies in which simple mixtures have been investigated. Finally, we discuss some of the effects of mixtures at a molecular level...
  33. ncbi request reprint Use of bipolar parallel electrodes for well-controlled microstimulation in a mouse hippocampal brain slice
    Bogdan Neagu
    Department of Biomedical Sciences, School of Public Health, State University of New York at Albany, East Campus, Room A 217, One University Place, Rensselaer, NY 12144, USA
    J Neurosci Methods 144:153-63. 2005
    ..The charge needed to elicit physiological responses was in the range of 1-40 nC (the lower values for the PE) suggesting that use of PEs is most advantageous for well-controlled microstimulation studies in brain slices...
  34. ncbi request reprint Polychlorinated biphenyl (PCB) exposure assessment by multivariate statistical analysis of serum congener profiles in an adult Native American population
    Anthony P DeCaprio
    Institute for Health and the Environment, University at Albany, State University of New York, Albany, NY 12144, USA
    Environ Res 98:284-302. 2005
    ..The results confirm the utility of a multivariate exploratory analysis approach to congener-specific PCB data and provide additional insight into the exposure and individual factors that determine PCB body burden in this population...
  35. pmc Relationship of thyroid hormone levels to levels of polychlorinated biphenyls, lead, p,p'- DDE, and other toxicants in Akwesasne Mohawk youth
    Lawrence M Schell
    Department of Anthropology, University at Albany, State University of New York, Albany, New York 12222, USA
    Environ Health Perspect 116:806-13. 2008
    ..Chronic exposure to multiple toxicants is common but difficult to analyze, and most prior studies have focused on adults or newborns, creating a gap in our understanding of multitoxicant effects among adolescents...
  36. doi request reprint Contribution of NMDA receptor-mediated component to the EPSP in mouse Schaffer collateral synapses under single pulse stimulation protocol
    Bogdan Neagu
    Department of Biomedical Sciences, School of Public Health, State University of New York at Albany, Rensselaer, NY 12144, USA
    Brain Res 1240:54-61. 2008
    ..25-0.26 mV/nC). Isolation of NMDA dependent components under physiological conditions when using a single pulse low stimulation protocol would allow more precise investigations of the NMDA dependent forms of synaptic plasticity...
  37. pmc Hospitalization rates for coronary heart disease in relation to residence near areas contaminated with persistent organic pollutants and other pollutants
    Alexander V Sergeev
    Institute for Health and the Environment, University at Albany, Rensselaer, New York 12144 3456, USA
    Environ Health Perspect 113:756-61. 2005
    ....
  38. pmc Low birth weight and residential proximity to PCB-contaminated waste sites
    Akerke Baibergenova
    School of Public Health, University at Albany, Rensselaer, New York 12144 3456, USA
    Environ Health Perspect 111:1352-7. 2003
    ..These observations support the hypothesis that living in a zip code near a PCB-contaminated site poses a risk of exposure and giving birth to an infant of low birth weight...
  39. ncbi request reprint The effects of protein kinase C activity on synaptic transmission in two areas of rat hippocampus
    Rifat J Hussain
    Institute for Health and the Environment, School of Public Health, University at Albany, One University Place, B242, Rensselaer, NY 12144, USA
    Brain Res 990:28-37. 2003
    ..There are developmental changes in the pattern of PKC isozymes, and both pre- and post-synaptic actions are important...
  40. ncbi request reprint Exposure to persistent organic pollutants and hypertensive disease
    Xiaoyu Huang
    Department of Biometry and Statistics, School of Public Health, University at Albany, SUNY, One University Place, Rm 131, Rensselaer, NY 12144, USA
    Environ Res 102:101-6. 2006
    ..The results support the hypothesis that living near hazardous waste sites, particularly sites containing POPs, may constitute a risk of exposure and of developing hypertension...
  41. pmc Human health and chemical mixtures: an overview
    D O Carpenter
    Department of Environmental Health and Toxicology, School of Public Health, University at Albany, Rensselaer, New York, USA
    Environ Health Perspect 106:1263-70. 1998
    ..We will also present examples on how different contaminants interact from toxicologic studies of polychlorinated biphenyls performed as part of our Albany, New York, Superfund Basic Research Program project...
  42. ncbi request reprint Corticospinal transmission to motoneurons in cervical spinal cord slices from adult rats
    N Hori
    School of Public Health, University at Albany, One University Place, Rm B242 Rensselaer, NY 12144 3456, USA
    Life Sci 72:389-96. 2002
    ..CNQX (but not AP-5) blocked EPSPs elicited by dorsal funiculus stimulation. Thus, corticospinal transmission to motoneurons is mediated primarily by non-NMDA glutamate receptors...
  43. ncbi request reprint A new fast electrophysiological response measured extracellularly in a mouse hippocampal brain slice
    Bogdan Neagu
    Department of Biomedical Sciences, School of Public Health, One University Place, Rensselaer, NY 12144, USA
    Neurosci Lett 381:179-84. 2005
    ..An undistorted recording of the first 2 ms of the sweep gives useful information about the fast neuronal activity measured extracellularly, and cannot be regarded as a simple stimulus artifact...
  44. ncbi request reprint Asthma and infectious respiratory disease in children--correlation to residence near hazardous waste sites
    Jing Ma
    Institute for Health and the Environment, University at Albany, Rensselaer, NY 12144, USA
    Paediatr Respir Rev 8:292-8. 2007
    ..This evidence supports the hypothesis that living near a hazardous waste site increases risk of respiratory disease in children...
  45. ncbi request reprint Hippocampal long-term potentiation (LTP) is reduced by a coplanar PCB congener
    Mete Ozcan
    School of Public Health, University at Albany, One University Place, Rensselaer, NY 12144 3456, USA
    Neurotoxicology 25:981-8. 2004
    ..These observations provide evidence in support of the hypothesis that dioxin-like and non-dioxin-like PCB congeners are equally potent in causing the cognitive decrements seen in children exposed prenatally to PCBs...
  46. ncbi request reprint Benefits versus risks associated with consumption of fish and other seafood
    Sheila Bushkin-Bedient
    Institute for Health and the Environment, University at Albany, Rensselaer, New York, NY 12144 3429, USA
    Rev Environ Health 25:161-91. 2010
    ..Thus the question of benefits and risk from fish consumption is complex but very important...
  47. ncbi request reprint Consumption advisories for salmon based on risk of cancer and noncancer health effects
    Xiaoyu Huang
    Department of Biometry and Statistics, School of Public Health, University at Albany, Rensselaer, NY 12144, USA
    Environ Res 101:263-74. 2006
    ..For both of these in the worst case, farmed salmon from northern Europe, the advice was not more than three meals per month...
  48. ncbi request reprint Electromagnetic fields and cancer: the cost of doing nothing
    David O Carpenter
    Institute for Health and the Environment, University at Albany, New York, NY 12144 3429, USA
    Rev Environ Health 25:75-80. 2010
    ..While there are many unanswered questions, the cost of doing nothing will result in an increasing number of people, many of them young, developing cancer...
  49. ncbi request reprint A comparison of the roles of protein kinase C in long-term potentiation in rat hippocampal areas CA1 and CA3
    Rifat J Hussain
    Department of Environmental Health and Toxicology, School of Public Health, University at Albany, One University Place A217, Rensselaer, New York 12144 3456, USA
    Cell Mol Neurobiol 25:649-61. 2005
    ..5. Our studies indicate that different PKC isozymes are crucial to LTP induction in these two areas of hippocampus, and that there are development changes in the profile of isozymes...
  50. ncbi request reprint Ortho-substituted PCBs kill thymocytes
    Yuansheng Tan
    University at Albany, School of Public Health, Department of Environmental Health and Toxicology, Rensselaer, New York 12144, USA
    Toxicol Sci 76:328-37. 2003
    ..We hypothesize that PCB 52 incorporates into lipid bilayers and with its bulky, three-dimensional ortho-substituted congener structure disrupts membrane function to a greater degree than coplanar congeners...
  51. ncbi request reprint The mechanism of presynaptic long-term depression mediated by group I metabotropic glutamate receptors
    Yuansheng Tan
    Department of Environmental Health and Toxicology, School of Public Health, University at Albany, Rensselear, New York 12144, USA
    Cell Mol Neurobiol 23:187-203. 2003
    ..These are calcium spike width and amplitude, after-hyperpolarization (AHP), and spike frequency adaptation (SFA). 6. These results suggest that the DHPG-LTD results from modulation of the presynaptic calcium currents by group I mGluRs...
  52. ncbi request reprint Ortho-substituted PCBs kill cells by altering membrane structure
    Yuansheng Tan
    Department of Environmental Health and Toxicology, School of Public Health, University at Albany, Rensselaer, New York 12144, USA
    Toxicol Sci 80:54-9. 2004
    ..In the two cell types we have studied, the disruption is sufficient to cause death of the cell within a brief time...
  53. doi request reprint Effects of cholesterol and docosahexaenoic acid on cell viability and (Ca(2+))(i) levels in acutely isolated mouse thymocytes
    Suleyman Sandal
    Institute for Health and the Environment, University at Albany, Rensselaer, NY, USA
    Cell Biochem Funct 27:155-61. 2009
    ..These observations demonstrate that thymocyte viability is very sensitive to acute exposure to low concentrations of omega-3 fatty acids...
  54. ncbi request reprint Ortho-substituted but not coplanar PCBs rapidly kill cerebellar granule cells
    Yuansheng Tan
    University at Albany, School of Public Health, Department of Environmental Health and Toxicology, University at Albany, Rensselaer, New York 12144, USA
    Toxicol Sci 79:147-56. 2004
    ....
  55. doi request reprint Role of calcium and ROS in cell death induced by polyunsaturated fatty acids in murine thymocytes
    Aparna Prasad
    Department of Environmental Health Sciences, School of Public Health, University at Albany, Rensselaer, New York 12144, USA
    J Cell Physiol 225:829-36. 2010
    ..These results suggest that the six PUFAs we studied kill thymocytes by causing release of calcium from endoplasmic reticulum, which causes release of ROS from mitochondria which leads to cell death...
  56. ncbi request reprint The role of metals in the etiology of Alzheimer's disease
    Ivan Shcherbatykh
    Institute for Health and the Environment, University at Albany, Rensselaer, NY 12144 3429, USA
    J Alzheimers Dis 11:191-205. 2007
    ..This review summarizes studies which implicate a role for several metals in contributing to or causing AD...
  57. ncbi request reprint Cerebellar granule cell death induced by aluminum
    Jelena Tuneva
    Institute for Health and the Environment, University at Albany, SUNY, Rensselaer, NY 12144, USA
    Neurotox Res 9:297-304. 2006
    ..These observations suggest that the cell death is subsequent to intracellular accumulation of Al (III) and subsequent perturbation of cellular metabolism...
  58. pmc Risk-based consumption advice for farmed Atlantic and wild Pacific salmon contaminated with dioxins and dioxin-like compounds
    Jeffery A Foran
    Midwest Center for Environmental Science and Public Policy, 1845 N Farwell Avenue, Suite 100, Milwaukee, WI 53202, USA
    Environ Health Perspect 113:552-6. 2005
    ..S. Environmental Protection Agency. Consumption of farmed salmon at relatively low frequencies results in elevated exposure to dioxins and dioxin-like compounds with commensurate elevation in estimates of health risk...
  59. ncbi request reprint An ecosystem approach to the health effects of mercury in the Great Lakes basin ecosystem
    Michael Gilbertson
    International Joint Commission, 100 Ouellette Ave, 8th Floor, Windsor, Ont, Canada N9A 6T3
    Environ Res 95:240-6. 2004
    ....
  60. ncbi request reprint Modulatory effects of Aroclors 1221 and 1254 on bone turnover and vertebral histology in intact and ovariectomized rats
    Bayram Yilmaz
    Firat University Medical School, Department of Physiology, Elazig, Turkey
    Toxicol Lett 166:276-84. 2006
    ..However, A1254 produced necrotic areas in vertebral bone, and this effect was expanded in ovx animals. Our findings suggest that both Aroclor compounds interfere with bone turnover mechanisms, particularly in ovx rats...
  61. ncbi request reprint Global assessment of organic contaminants in farmed salmon
    Ronald A Hites
    School of Public and Environmental Affairs, Indiana University, Bloomington, IN 47405, USA
    Science 303:226-9. 2004
    ..Risk analysis indicates that consumption of farmed Atlantic salmon may pose health risks that detract from the beneficial effects of fish consumption...
  62. ncbi request reprint PCBs, PCDD/Fs, and organochlorine pesticides in farmed Atlantic salmon from Maine, eastern Canada, and Norway, and wild salmon from Alaska
    Susan D Shaw
    Marine Environmental Research Institute, P O Box 1652, Blue Hill, Maine 04614, USA
    Environ Sci Technol 40:5347-54. 2006
    ....
  63. ncbi request reprint Depleted uranium contamination by inhalation exposure and its detection after approximately 20 years: implications for human health assessment
    Randall R Parrish
    Department of Geology, University of Leicester, University Road, Leicester LE1 7RH, UK
    Sci Total Environ 390:58-68. 2008
    ..The method allows even a modest DU exposure to be identified where other less sensitive methods would have failed entirely. This should allow better assessment of historical exposure incidence than currently exists...
  64. ncbi request reprint PbCl2-induced hyperpolarization of rat thymocytes: involvement of charybdotoxin-sensitive K+ channels
    Yasutaka Nishizaki
    Laboratory of Cellular Signaling, Faculty of Integrated Arts and Sciences, University of Tokushima, Tokushima 770 8502, Japan
    Environ Toxicol 18:321-6. 2003
    ..The persistent activation of K+ channels by Pb2+, leading to persistent hyperpolarization, may be one mechanism whereby Pb2+ alters immune function, as membrane potential changes influence physiological functions of lymphocytes...
  65. ncbi request reprint Expansion of visual receptive fields in experimental glaucoma
    Wayne Michael King
    Departments of Ophthalmology and Cell Biology and Anatomy, New York Medical College, Valhalla, New York 10595, USA
    Vis Neurosci 23:137-42. 2006
    ..We suggest that this increase in the size of receptive fields of glaucomatous eyes may be related to the increase in the size of dendritic arbors of the surviving ganglion cells in retina...
  66. ncbi request reprint Comparative effects of technical toxaphene, 2,5-dichloro-3-biphenylol and octabromodiphenylether on cell viability, [Ca2+]i levels and membrane fluidity in mouse thymocytes
    Suleyman Sandal
    Department of Physiology, Faculty of Medicine, Firat University, 23119 Elazig, Turkey
    Toxicol Lett 151:417-28. 2004
    ..These observations suggest that alterations of membrane fluidity of thymocytes, whether it be an increase or decrease, can cause cytotoxicity...
  67. ncbi request reprint Risks and benefits of seafood consumption
    Jeffery A Foran
    Am J Prev Med 30:438-9; author reply 441-4. 2006
  68. ncbi request reprint Lipid composition and contaminants in farmed and wild salmon
    M Coreen Hamilton
    AXYS Analytical Services, Sidney, British Columbia, Canada, School of Public and Environmental Affairs, Indiana University, Bloomington, Indiana 47405, USA
    Environ Sci Technol 39:8622-9. 2005
    ..The presence of these contaminants may reduce the net health benefits derived from the consumption of farmed salmon, despite the presence of the high level of n-3 fatty acids in these fish...
  69. ncbi request reprint Quantitative analysis of the benefits and risks of consuming farmed and wild salmon
    Jeffery A Foran
    Midwest Center for Environmental Science and Public Policy, Milwaukee, WI, USA
    J Nutr 135:2639-43. 2005
    ....
  70. ncbi request reprint Effects of PCB 52 and PCB 77 on cell viability, [Ca(2+)](i) levels and membrane fluidity in mouse thymocytes
    Bayram Yilmaz
    Firat University, Department of Physiology, Faculty of Medicine, 23119 Elazig, Turkey
    Toxicology 217:184-93. 2006
    ..These observations are consistent with previous results that suggest that ortho-substituted PCB congeners dissolve in cell membrane and cause greater disruption of function than do dioxin-like PCB congeners...
  71. ncbi request reprint Effects of PCBs 52 and 77 on Th1/Th2 balance in mouse thymocyte cell cultures
    Suleyman Sandal
    Department of Physiology, Medical School, Firat University, Elazig, Turkey
    Immunopharmacol Immunotoxicol 27:601-13. 2005
    ..Our results show that the cytokine production profile was significantly shifted to Th1 by both ortho-substituted and coplanar PCB congeners in mouse thymocyte cultures...
  72. ncbi request reprint Effects of polycyclic aromatic hydrocarbon-containing oil mixtures on generation of reactive oxygen species and cell viability in MCF-7 breast cancer cells
    Bayram Yilmaz
    Faculty of Medicine, Department of Physiology, Yeditepe University, Istanbul, Turkey
    J Toxicol Environ Health A 70:1108-15. 2007
    ..The present findings suggest that oil samples with higher concentrations of polycyclic aromatic hydrocarbons may exert adverse effects on human mammary epithelial tissue through induction of oxidative stress...
  73. ncbi request reprint TCDD and PCBs inhibit breast cancer cell proliferation in vitro
    Gideon N Oenga
    Wadsworth Center, New York State Department of Health, Albany, NY 12201 0509, USA
    Toxicol In Vitro 18:811-9. 2004
    ..34 (1997) 237]. Our results thus show an unexpected different pattern for the inhibitory effects of PCBs congeners on E(2)-mediated cell proliferation...
  74. ncbi request reprint Rodent lymphocytes express functionally active glutamate receptors
    Alexander A Boldyrev
    Department of Biochemistry, Center for Molecular Medicine and International Biotechnological Center, M V Lomonosov Moscow State University, 119992 Moscow, Russia
    Biochem Biophys Res Commun 324:133-9. 2004
    ..These results show that lymphocyte iGluR NR1 and mGluR Group III receptors may be involved in controlling rodent lymphocyte functions and longevity as they regulate events in cell proliferation, maturation, and death...
  75. ncbi request reprint A survey of metals in tissues of farmed Atlantic and wild Pacific salmon
    Jeffery A Foran
    Midwest Center for Environmental Science and Public Policy, Milwaukee, Wisconsin 53202, USA
    Environ Toxicol Chem 23:2108-10. 2004
    ..None of the contaminants exceeded federal standards or guidance levels...
  76. doi request reprint Genotoxic effects of PCB 52 and PCB 77 on cultured human peripheral lymphocytes
    Suleyman Sandal
    Yeditepe University, Faculty of Medicine, Department of Physiology, 34755 Istanbul, Turkey
    Mutat Res 654:88-92. 2008
    ..001). Our results indicate that both the non-coplanar PCB 52 and coplanar PCB 77 cause DNA damage, and that the ortho-substituted congener was significantly more potent than the dioxin-like coplanar congener...
  77. pmc Meeting report: threats to human health and environmental sustainability in the pacific basin
    Robert G Arnold
    Department of Chemical and Environmental Engineering, The University of Arizona, Tucson, Arizona, USA
    Environ Health Perspect 115:1770-5. 2007
    ..The conference program provided talks on arsenic toxicology, treatment technologies, management of arsenic-bearing residuals from water treatment, and the probable societal costs and benefits of arsenic management...

Research Grants1

  1. Effects of Dioxin on Vietnamese Civilians
    David Carpenter; Fiscal Year: 2004
    ..7. ..