Research Topics
Species | Morgan E CarlsonSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
Relative roles of TGF-beta1 and Wnt in the systemic regulation and aging of satellite cell responsesMorgan E Carlson
Department of Bioengineering, University of California Berkeley, Berkeley, CA 94720, USA
Aging Cell 8:676-89. 2009....
Differentiation rather than aging of muscle stem cells abolishes their telomerase activityMatthew S O'Connor
Department of Bioengineering, University of California, Berkeley, CA 94720, USA
Biotechnol Prog 25:1130-7. 2009....
Molecular aging and rejuvenation of human muscle stem cellsMorgan E Carlson
Department of Bioengineering, University of California, Berkeley, Berkeley CA, USA
EMBO Mol Med 1:381-91. 2009..These findings strongly suggest that aging of human muscle maintenance and repair can be reversed by 'youthful' calibration of specific molecular pathways...
Imbalance between pSmad3 and Notch induces CDK inhibitors in old muscle stem cellsMorgan E Carlson
Department of Bioengineering, University of California, Berkeley, California 94720, USA
Nature 454:528-32. 2008..Thus a balance between endogenous pSmad3 and active Notch controls the regenerative competence of muscle stem cells, and deregulation of this balance in the old muscle microniche interferes with regeneration...
Loss of stem cell regenerative capacity within aged nichesMorgan E Carlson
Department of Bioengineering, University of California, Berkeley, Berkeley, CA 94702, USA
Aging Cell 6:371-82. 2007..Comprehensively, this work points toward novel venues for in situ restoration of tissue repair in the old and identifies critical determinants of successful cell-replacement therapies for aged degenerating organs...
Notch signaling pathway and tissue engineeringMorgan E Carlson
Department of Bioengineering, University of California at Berkeley, Berkeley, California
Front Biosci 12:5143-56. 2007..Such methods will likely facilitate the engineering and dynamic remodeling of tissues composed of stem, progenitor and differentiated cells derived from an initially equivalent cell population...
The thermodynamic principles of isochoric cryopreservationBoris Rubinsky
Department of Mechanical Engineering, University of California at Berkeley, Berkeley, CA 94720, USA
Cryobiology 50:121-38. 2005..The technology for isochoric cryopreservation is very simple; freezing in a constant volume chamber. Using a simple isochoric cryopreservation device, we confirm the theoretical thermodynamic predictions...
Regulating the Notch pathway in embryonic, adult and old stem cellsMorgan E Carlson
Department of Bioengineering, UC Berkeley, Berkeley, CA 94720 1762, USA
Curr Opin Pharmacol 7:303-9. 2007..g. Alzheimer's, Alagille Syndrome, various cancers and other disease states)...
Aging of signal transduction pathways, and pathologyMorgan E Carlson
Department of Bioengineering, University of California, Berkeley, Berkeley, California 94720 1762, USA
Exp Cell Res 314:1951-61. 2008....
