Gregory C Carlson

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. pmc Glutamate receptor dysfunction and drug targets across models of autism spectrum disorders
    Greg C Carlson
    Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA
    Pharmacol Biochem Behav 100:850-4. 2012
  2. pmc Dysbindin-1 mutant mice implicate reduced fast-phasic inhibition as a final common disease mechanism in schizophrenia
    Gregory C Carlson
    Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104 3403, USA
    Proc Natl Acad Sci U S A 108:E962-70. 2011
  3. pmc High fat diet produces brain insulin resistance, synaptodendritic abnormalities and altered behavior in mice
    Steven E Arnold
    Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania, 125 South 31st St, Philadelphia, PA 19104, USA Electronic address
    Neurobiol Dis 67:79-87. 2014
  4. pmc Divergent functional effects of sazetidine-a and varenicline during nicotine withdrawal
    Jill R Turner
    Department of Pharmacology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
    Neuropsychopharmacology 38:2035-47. 2013
  5. pmc Temporally dependent changes in cocaine-induced synaptic plasticity in the nucleus accumbens shell are reversed by D1-like dopamine receptor stimulation
    Pavel I Ortinski
    Department of Psychiatry, Center for Neurobiology and Behavior, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA
    Neuropsychopharmacology 37:1671-82. 2012
  6. pmc Parvalbumin cell ablation of NMDA-R1 causes increased resting network excitability with associated social and self-care deficits
    Eddie N Billingslea
    Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA
    Neuropsychopharmacology 39:1603-13. 2014
  7. pmc Akt1 deficiency in schizophrenia and impairment of hippocampal plasticity and function
    Darrick T Balu
    Department of Pharmacology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Hippocampus 22:230-40. 2012

Research Grants

Collaborators

Detail Information

Publications7

  1. pmc Glutamate receptor dysfunction and drug targets across models of autism spectrum disorders
    Greg C Carlson
    Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA
    Pharmacol Biochem Behav 100:850-4. 2012
    ..Further development of preclinical models focusing on glutamate receptors may provide tools to target a clinically important subset of ASD symptoms...
  2. pmc Dysbindin-1 mutant mice implicate reduced fast-phasic inhibition as a final common disease mechanism in schizophrenia
    Gregory C Carlson
    Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104 3403, USA
    Proc Natl Acad Sci U S A 108:E962-70. 2011
    ..Furthermore, these data implicate reduced fast-phasic inhibition as a common underlying mechanism of schizophrenia-associated intermediate phenotypes...
  3. pmc High fat diet produces brain insulin resistance, synaptodendritic abnormalities and altered behavior in mice
    Steven E Arnold
    Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania, 125 South 31st St, Philadelphia, PA 19104, USA Electronic address
    Neurobiol Dis 67:79-87. 2014
    ..These findings indicate that HFD is associated with telencephalic insulin resistance and deleterious effects on synaptic integrity and cognitive behaviors...
  4. pmc Divergent functional effects of sazetidine-a and varenicline during nicotine withdrawal
    Jill R Turner
    Department of Pharmacology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
    Neuropsychopharmacology 38:2035-47. 2013
    ..These findings highlight the importance of drug history in understanding the mechanisms through which nicotinic compounds may be aiding smoking cessation in individuals experiencing withdrawal-associated anxiety...
  5. pmc Temporally dependent changes in cocaine-induced synaptic plasticity in the nucleus accumbens shell are reversed by D1-like dopamine receptor stimulation
    Pavel I Ortinski
    Department of Psychiatry, Center for Neurobiology and Behavior, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA
    Neuropsychopharmacology 37:1671-82. 2012
    ....
  6. pmc Parvalbumin cell ablation of NMDA-R1 causes increased resting network excitability with associated social and self-care deficits
    Eddie N Billingslea
    Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA
    Neuropsychopharmacology 39:1603-13. 2014
    ..Although previous data suggest that MPEP may be beneficial for core features of autism spectrum disorders, current data suggest that such effects require intact function of NMDAR on PV interneurons. ..
  7. pmc Akt1 deficiency in schizophrenia and impairment of hippocampal plasticity and function
    Darrick T Balu
    Department of Pharmacology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Hippocampus 22:230-40. 2012
    ..Taken together, these results implicate the Akt1 isoform in regulating hippocampal neuroplasticity and cognition and in contributing to the etiology of schizophrenia...

Research Grants1

  1. Functional circuit disorders of sensory cortex in ASD and RTT
    Gregory C Carlson; Fiscal Year: 2010
    ..Leading from positive preliminary data, it further tests the efficacy of antidepressants to reverse these differences. ..