Christopher S Carlson

Summary

Affiliation: University of Washington
Country: USA

Publications

  1. pmc Selecting a maximally informative set of single-nucleotide polymorphisms for association analyses using linkage disequilibrium
    Christopher S Carlson
    Department of Genome Sciences, University of Washington, Seattle, WA, 98195, USA
    Am J Hum Genet 74:106-20. 2004
  2. ncbi request reprint TagSNP analyses of the PON gene cluster: effects on PON1 activity, LDL oxidative susceptibility, and vascular disease
    Christopher S Carlson
    The Fred Hutchinson Cancer Research Center, Division of Public Health Sciences, The University of Washington, Seattle, USA
    J Lipid Res 47:1014-24. 2006
  3. pmc Investigation of gene-by-sex interactions for lipid traits in diverse populations from the population architecture using genomics and epidemiology study
    Kira C Taylor
    Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
    BMC Genet 14:33. 2013
  4. ncbi request reprint Mapping complex disease loci in whole-genome association studies
    Christopher S Carlson
    Department of Genome Sciences, University of Washington, 1705 NE Pacific, Seattle, Washington 98195 7730, USA
    Nature 429:446-52. 2004
  5. pmc Genomic regions exhibiting positive selection identified from dense genotype data
    Christopher S Carlson
    Department of Genome Sciences, University of Washington, Seattle, Washington 98195 7730, USA
    Genome Res 15:1553-65. 2005
  6. pmc Polymorphisms within the C-reactive protein (CRP) promoter region are associated with plasma CRP levels
    Christopher S Carlson
    Department of Genome Sciences, University of Washington, Seattle, WA, USA
    Am J Hum Genet 77:64-77. 2005
  7. pmc Common coding variants of the HNF1A gene are associated with multiple cardiovascular risk phenotypes in community-based samples of younger and older European-American adults: the Coronary Artery Risk Development in Young Adults Study and The Cardiovascula
    Alexander P Reiner
    Department of Epidemiology, University of Washington, Seattle, WA 98195, USA
    Circ Cardiovasc Genet 2:244-54. 2009
  8. doi request reprint Associations between common fibrinogen gene polymorphisms and cardiovascular disease in older adults. The Cardiovascular Health Study
    Cara L Carty
    Cardiovascular Health Research Unit, Department of Epidemiology, University of Washington, 1760 Minor Avenue, Seattle, WA 98101, USA
    Thromb Haemost 99:388-95. 2008
  9. pmc Polymorphisms of the IL1-receptor antagonist gene (IL1RN) are associated with multiple markers of systemic inflammation
    Alexander P Reiner
    Department of Epidemiology, Box 357236, University of Washington, Seattle, Washington 98195, USA
    Arterioscler Thromb Vasc Biol 28:1407-12. 2008
  10. pmc Genetic variation in the progesterone receptor and metabolism pathways and hormone therapy in relation to breast cancer risk
    Kerryn W Reding
    Department of Epidemiology, School of Public Health, University of Washington, Seattle, Washington 98109, USA
    Am J Epidemiol 170:1241-9. 2009

Detail Information

Publications59

  1. pmc Selecting a maximally informative set of single-nucleotide polymorphisms for association analyses using linkage disequilibrium
    Christopher S Carlson
    Department of Genome Sciences, University of Washington, Seattle, WA, 98195, USA
    Am J Hum Genet 74:106-20. 2004
    ..We demonstrate that, although common variation tends to be shared between populations, tagSNPs should be selected separately for populations with different ancestries...
  2. ncbi request reprint TagSNP analyses of the PON gene cluster: effects on PON1 activity, LDL oxidative susceptibility, and vascular disease
    Christopher S Carlson
    The Fred Hutchinson Cancer Research Center, Division of Public Health Sciences, The University of Washington, Seattle, USA
    J Lipid Res 47:1014-24. 2006
    ....
  3. pmc Investigation of gene-by-sex interactions for lipid traits in diverse populations from the population architecture using genomics and epidemiology study
    Kira C Taylor
    Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
    BMC Genet 14:33. 2013
    ..Here, we investigated whether GWAS-identified SNPs for lipid traits exhibited heterogeneity by sex in the Population Architecture using Genomics and Epidemiology (PAGE) study...
  4. ncbi request reprint Mapping complex disease loci in whole-genome association studies
    Christopher S Carlson
    Department of Genome Sciences, University of Washington, 1705 NE Pacific, Seattle, Washington 98195 7730, USA
    Nature 429:446-52. 2004
    ....
  5. pmc Genomic regions exhibiting positive selection identified from dense genotype data
    Christopher S Carlson
    Department of Genome Sciences, University of Washington, Seattle, Washington 98195 7730, USA
    Genome Res 15:1553-65. 2005
    ....
  6. pmc Polymorphisms within the C-reactive protein (CRP) promoter region are associated with plasma CRP levels
    Christopher S Carlson
    Department of Genome Sciences, University of Washington, Seattle, WA, USA
    Am J Hum Genet 77:64-77. 2005
    ..We also demonstrate the functional importance of these SNPs in vitro...
  7. pmc Common coding variants of the HNF1A gene are associated with multiple cardiovascular risk phenotypes in community-based samples of younger and older European-American adults: the Coronary Artery Risk Development in Young Adults Study and The Cardiovascula
    Alexander P Reiner
    Department of Epidemiology, University of Washington, Seattle, WA 98195, USA
    Circ Cardiovasc Genet 2:244-54. 2009
    ..Common polymorphisms of the HNF-1 alpha gene (HNF1A) were recently associated with plasma C-reactive protein and gamma-glutamyl transferase concentration in middle-aged to older European Americans (EA)...
  8. doi request reprint Associations between common fibrinogen gene polymorphisms and cardiovascular disease in older adults. The Cardiovascular Health Study
    Cara L Carty
    Cardiovascular Health Research Unit, Department of Epidemiology, University of Washington, 1760 Minor Avenue, Seattle, WA 98101, USA
    Thromb Haemost 99:388-95. 2008
    ..9 (95%CI: 1.3-2.7). In conclusion, while fibrinogen genetic variation was strongly associated with fibrinogen levels, there was less evidence of association with the more complex outcomes of IMT and CVD events...
  9. pmc Polymorphisms of the IL1-receptor antagonist gene (IL1RN) are associated with multiple markers of systemic inflammation
    Alexander P Reiner
    Department of Epidemiology, Box 357236, University of Washington, Seattle, Washington 98195, USA
    Arterioscler Thromb Vasc Biol 28:1407-12. 2008
    ..Circulating levels of acute phase reactant proteins such as plasma C-reactive protein (CRP) are likely influenced by multiple genes regulating the innate immune response...
  10. pmc Genetic variation in the progesterone receptor and metabolism pathways and hormone therapy in relation to breast cancer risk
    Kerryn W Reding
    Department of Epidemiology, School of Public Health, University of Washington, Seattle, Washington 98109, USA
    Am J Epidemiol 170:1241-9. 2009
    ..1, 2.2) but not in never users (P(heterogeneity) = 0.02). Interpretation of these subgroup associations must await the results of similar studies conducted in other populations...
  11. ncbi request reprint USF1 gene variants, cardiovascular risk, and mortality in European Americans: analysis of two US cohort studies
    Alexander P Reiner
    Department of Epidemiology, Box 357236, University of Washington, Seattle, WA 98195, USA
    Arterioscler Thromb Vasc Biol 27:2736-42. 2007
    ....
  12. pmc Genetic risk factors for BMI and obesity in an ethnically diverse population: results from the population architecture using genomics and epidemiology (PAGE) study
    Megan D Fesinmeyer
    Department of Biostatistics and Biomathematics, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
    Obesity (Silver Spring) 21:835-46. 2013
    ..However, studies of this complex trait have focused on ancestrally European populations, despite the high prevalence of obesity in some minority groups...
  13. pmc Population history and natural selection shape patterns of genetic variation in 132 genes
    Joshua M Akey
    Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
    PLoS Biol 2:e286. 2004
    ..More generally, our results have important implications for mapping genes underlying complex human diseases...
  14. pmc C-reactive protein, interleukin-6, and prostate cancer risk in men aged 65 years and older
    Brandon L Pierce
    Institute for Public Health Genetics, University of Washington, Seattle, WA, USA
    Cancer Causes Control 20:1193-203. 2009
    ..21). Our results suggest that circulating CRP and IL-6 do not influence PCa risk. SNPs at the CRP locus are not associated with PCa risk in this cohort, while the association between rs1800795 and PCa risk warrants further investigation...
  15. ncbi request reprint Thromboxane synthase (TBXAS1) polymorphisms in African-American and Caucasian populations: evidence for selective pressure
    Cornelia M Ulrich
    Fred Hutchinson Cancer Research Center, Cancer Prevention Program, University of Washington, Seattle, Washington 98109 1024, USA
    Hum Mutat 26:394-5. 2005
    ..Given the evolutionary evidence, these variants may be functional and therefore of relevance for disease endpoints related to inflammation and angiogenesis, as well as for the pharmacogenetics of non-steroidal anti-inflammatory drugs...
  16. pmc Genetic variation in the lipoxygenase pathway and risk of colorectal neoplasia
    Sarah E Kleinstein
    Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Genes Chromosomes Cancer 52:437-49. 2013
    ..Genetic variability in ALOXs may affect risk of colorectal neoplasia, particularly for rectal cancer. Additionally, genetic variability in FLAP and ALOX15 may modify the protective effect of NSAID use against colorectal neoplasia...
  17. pmc Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis
    Ulrike Peters
    Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    Gastroenterology 144:799-807.e24. 2013
    ..Heritable factors contribute to the development of colorectal cancer. Identifying the genetic loci associated with colorectal tumor formation could elucidate the mechanisms of pathogenesis...
  18. pmc Genetic variability in IL23R and risk of colorectal adenoma and colorectal cancer
    Elizabeth M Poole
    Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Cancer Epidemiol 36:e104-10. 2012
    ..These data provide some evidence that genetic variability in IL23R may contribute to rectal cancer risk and should be evaluated in additional studies...
  19. ncbi request reprint TagSNP evaluation for the association of 42 inflammation loci and vascular disease: evidence of IL6, FGB, ALOX5, NFKBIA, and IL4R loci effects
    Christopher S Carlson
    Division of Public Health Sciences, The Fred Hutchinson Cancer Research Center, The University of Washington, Seattle, WA, USA
    Hum Genet 121:65-75. 2007
    ..The NFKBIA and IL10RA expression levels significantly differed between subjects with CAAD and controls. These results support a role for genetic variation related to inflammation in CAAD and a causal role for specific gene products...
  20. ncbi request reprint 5' and 3' region variability in the dopamine transporter gene (SLC6A3), pesticide exposure and Parkinson's disease risk: a hypothesis-generating study
    Samir N P Kelada
    Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA 98105, USA
    Hum Mol Genet 15:3055-62. 2006
    ..66 (95% CI: 1.73-18.53). Thus, allelic variants in SLC6A3, which affect gene expression, are associated with PD in this population and may interact with occupational pesticide exposure to increase PD risk...
  21. ncbi request reprint Direct detection of null alleles in SNP genotyping data
    Christopher S Carlson
    Department of Genome Sciences, University of Washington, Seattle, WA 98195 7730, USA
    Hum Mol Genet 15:1931-7. 2006
    ..Detecting unexpected null alleles not only has benefits in QC of genotype data but may also be valuable in detecting rare, functional null alleles that would otherwise be missed...
  22. ncbi request reprint Sequence diversity, natural selection and linkage disequilibrium in the human T cell receptor alpha/delta locus
    Rachel Mackelprang
    Department of Genome Sciences, University of Washington, 357730, Seattle, WA, 98195 7730, USA
    Hum Genet 119:255-66. 2006
    ..Furthermore, we explore signatures of natural selection across V genes. We find evidence of strong directional selection at this locus as evidenced by unusually high values of Fst...
  23. doi request reprint Soluble P-selectin, SELP polymorphisms, and atherosclerotic risk in European-American and African-African young adults: the Coronary Artery Risk Development in Young Adults (CARDIA) Study
    Alexander P Reiner
    Departments of Epidemiology, University of Washington, Seattle, WA 98195, USA
    Arterioscler Thromb Vasc Biol 28:1549-55. 2008
    ..To characterize the genetic and clinical correlates of soluble P-selectin, and the relationship of P-selectin to atherosclerotic risk, in young European-American (EA) and African-American (AA) adults...
  24. pmc Genetic variation in prostaglandin E2 synthesis and signaling, prostaglandin dehydrogenase, and the risk of colorectal adenoma
    Elizabeth M Poole
    Fred Hutchinson Cancer Research Center, University of Washington, Seattle, Washington, USA
    Cancer Epidemiol Biomarkers Prev 19:547-57. 2010
    ..Prostaglandins are metabolites of omega-6 and omega-3 polyunsaturated fatty acids; their biosynthesis is the primary target of nonsteroidal anti-inflammatory drugs (NSAID), which reduce colorectal neoplasia risk...
  25. ncbi request reprint Polymorphisms predicted to alter function in prostaglandin E2 synthase and prostaglandin E2 receptors
    Jeannette Bigler
    Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
    Pharmacogenet Genomics 17:221-7. 2007
    ..Several lines of evidence implicate prostaglandin E2 in carcinogenesis; this study aimed to identify genetic variants in genes related to prostaglandin E2 synthesis and signaling...
  26. pmc Examination of ancestral informative markers and self-reported race with tumor characteristics of breast cancer among Black and White women
    Kerryn W Reding
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, Mail Stop M4 B874, Seattle, WA 98109 1024, USA
    Breast Cancer Res Treat 134:801-9. 2012
    ..These study results suggest that subtle differences in percent African ancestry are less important than the overall presence of African ancestry in relation to BC tumor characteristics...
  27. pmc Haplotype diversity across 100 candidate genes for inflammation, lipid metabolism, and blood pressure regulation in two populations
    Dana C Crawford
    Department of Genome Sciences, University of Washington, Seattle 98195 7730, USA
    Am J Hum Genet 74:610-22. 2004
    ....
  28. ncbi request reprint Efficient selection of tagging single-nucleotide polymorphisms in multiple populations
    Bryan N Howie
    Department of Genome Sciences, University of Washington, Box 357730, Seattle, WA 98195, USA
    Hum Genet 120:58-68. 2006
    ..Using populations of African, Asian, and European ancestry, we also show that an optimal multi-population set of tagSNPs can be substantially smaller (up to 44%) than a typical set obtained through independent or sequential selection...
  29. ncbi request reprint Additional SNPs and linkage-disequilibrium analyses are necessary for whole-genome association studies in humans
    Christopher S Carlson
    Department of Genome Sciences, University of Washington, 1705 NE Pacific, Seattle, Washington 98195 7730, USA
    Nat Genet 33:518-21. 2003
    ....
  30. doi request reprint Multiple independent genetic variants in the 8q24 region are associated with prostate cancer risk
    Claudia A Salinas
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    Cancer Epidemiol Biomarkers Prev 17:1203-13. 2008
    ....
  31. pmc Genetic polymorphisms in the catechol estrogen metabolism pathway and breast cancer risk
    Kerryn W Reding
    University of Washington, Seattle, WA 98109, USA
    Cancer Epidemiol Biomarkers Prev 18:1461-7. 2009
    ....
  32. ncbi request reprint Dopamine transporter (SLC6A3) 5' region haplotypes significantly affect transcriptional activity in vitro but are not associated with Parkinson's disease
    Samir N Kelada
    Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington 98105, USA
    Pharmacogenet Genomics 15:659-68. 2005
    ..In addition, our findings provide further evidence supporting an association of PD with the VNTR polymorphism...
  33. ncbi request reprint Common genetic variation in the prothrombin gene, hormone therapy, and incident nonfatal myocardial infarction in postmenopausal women
    Lucia A Hindorff
    Department of Epidemiology, School of Public Health, University of Washington, Seattle, WA 98101, USA
    Am J Epidemiol 163:600-7. 2006
    ..These preliminary results suggest that common genetic variants in the prothrombin gene or other variants in linkage disequilibrium are associated with myocardial infarction in postmenopausal women...
  34. ncbi request reprint High-throughput genotyping of intermediate-size structural variation
    Tera L Newman
    Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA 98195, USA
    Hum Mol Genet 15:1159-67. 2006
    ..The approach we describe may be used to characterize a large number of individuals in a cost-effective manner once the sequence organization of ISVs is known...
  35. pmc Common and rare von Willebrand factor (VWF) coding variants, VWF levels, and factor VIII levels in African Americans: the NHLBI Exome Sequencing Project
    JILL M JOHNSEN
    Department of Medicine, University of Washington, Seattle, WA, USA
    Blood 122:590-7. 2013
    ..Arg2287Trp were each associated with 30 to 40 IU/dL lower VWF level (P < .001). In summary, several common and rare VWF missense variants contribute to phenotypic differences in VWF and FVIII among AAs. ..
  36. pmc Effects of smoking on the genetic risk of obesity: the population architecture using genomics and epidemiology study
    Megan D Fesinmeyer
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    BMC Med Genet 14:6. 2013
    ..Although smoking behavior is known to affect body mass index (BMI), the potential for smoking to influence genetic associations with BMI is largely unexplored...
  37. pmc Estrogen-related genes and their contribution to racial differences in breast cancer risk
    Kerryn W Reding
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    Cancer Causes Control 23:671-81. 2012
    ..02) and with CYP17A1 in Black women (p value = 0.04). This analysis suggests that HT use may modify the effect of variation in estrogen-related genes on breast cancer risk, which may affect Black and White women to a different extent...
  38. pmc The impact of patents on the development of genome-based clinical diagnostics: an analysis of case studies
    Brandon L Pierce
    Institute for Public Health Genetics, University of Washington, Seattle, WA, USA
    Genet Med 11:202-9. 2009
    ....
  39. ncbi request reprint Genetic ancestry, population sub-structure, and cardiovascular disease-related traits among African-American participants in the CARDIA Study
    Alexander P Reiner
    Department of Epidemiology, University of Washington, Box 357236, Seattle, WA 98195, USA
    Hum Genet 121:565-75. 2007
    ..These results demonstrate the potential for confounding of genetic associations with some cardiovascular disease-related traits in large studies involving US African-Americans...
  40. pmc Evaluating the accuracy of a functional SNP annotation system
    Terry H Shen
    Departments of Biomedical and Health Informatics, University of Washington, Seattle, WA, USA
    BMC Bioinformatics 10:S11. 2009
    ..To evaluate the SNPit system, we developed an alternative gold standard to measure accuracy using sensitivity and specificity. The results of our evaluation demonstrated that our alternative gold standard produced encouraging results...
  41. ncbi request reprint Estimating the heritability of colorectal cancer
    Shuo Jiao
    Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
    Hum Mol Genet 23:3898-905. 2014
    ..26 × 10(-2)). In summary, our results suggest that known CRC SNPs only explain a small proportion of the heritability and more common SNPs have yet to be identified. ..
  42. pmc Replication of loci influencing ages at menarche and menopause in Hispanic women: the Women's Health Initiative SHARe Study
    Christina T L Chen
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Hum Mol Genet 21:1419-32. 2012
    ..We provide evidence that genetic variants influencing reproductive traits identified in European populations are also important in minority US Hispanic women...
  43. pmc Evaluation of probabilistic and logical inference for a SNP annotation system
    Terry H Shen
    Department of Biomedical and Health Informatics, University of Washington, Seattle, WA 98195 7240, USA
    J Biomed Inform 43:407-18. 2010
    ..Evaluations of the methods demonstrate the overall strong predictive value of logical, and logical with probabilistic, inference applied to the domain of SNP annotation...
  44. ncbi request reprint Sequence variation in the human T-cell receptor loci
    Rachel Mackelprang
    Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA
    Immunol Rev 190:26-39. 2002
    ..This suggests that meaningful association studies in the TCR loci will require the analysis and typing of large marker sets to fully evaluate the role of TCR loci in common disease susceptibility in human populations...
  45. pmc Pattern of sequence variation across 213 environmental response genes
    Robert J Livingston
    Department of Genome Sciences, University of Washington, Seattle, Washington 98195 7730, USA
    Genome Res 14:1821-31. 2004
    ..The implications for the use of these data in direct and indirect association studies of environmentally induced diseases are discussed...
  46. pmc Meta-analysis of new genome-wide association studies of colorectal cancer risk
    Ulrike Peters
    Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, USA
    Hum Genet 131:217-34. 2012
    ..03; combined p value 1.9 × 10(-4)). Our study suggests a complex nature of the contribution of common genetic variants to risk for colorectal cancer...
  47. pmc Vitamin D related genes, CYP24A1 and CYP27B1, and colon cancer risk
    Linda M Dong
    Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Cancer Epidemiol Biomarkers Prev 18:2540-8. 2009
    ..As this is the first study to evaluate these genes in relation to colon cancer, additional studies are needed to confirm these results...
  48. pmc SNPit: a federated data integration system for the purpose of functional SNP annotation
    Terry H Shen
    Department of Biomedical and Health Informatics, University of Washington, Seattle, WA 98195 7240, USA
    Comput Methods Programs Biomed 95:181-9. 2009
    ..A tool that can help to integrate and analyze the potential functional significance of SNPs is important for understanding the results from genome wide association studies...
  49. pmc Efficient identification of rare variants in large populations: deep re-sequencing the CRP locus in the CARDIA study
    Christina T L Chen
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Nucleic Acids Res 41:e85. 2013
    ....
  50. doi request reprint High-throughput sequencing of T-cell receptors reveals a homogeneous repertoire of tumour-infiltrating lymphocytes in ovarian cancer
    Ryan O Emerson
    Adaptive Biotechnologies, Seattle, WA, USA
    J Pathol 231:433-40. 2013
    ..We conclude that the cellular adaptive immune response within ovarian carcinomas is spatially homogeneous and distinct from the T-cell compartment of peripheral blood...
  51. doi request reprint Deep sequencing of the human TCRγ and TCRβ repertoires suggests that TCRβ rearranges after αβ and γδ T cell commitment
    Anna M Sherwood
    Adaptive TCR, 307 Westlake Avenue North, Seattle, WA 98109, USA
    Sci Transl Med 3:90ra61. 2011
    ..Because high-throughput sequencing of TCRs is translated into the clinic for monitoring minimal residual for leukemia/lymphoma, our data suggest the sequencing target should be TCRγ...
  52. ncbi request reprint Cyclooxygenase 1 (COX1) polymorphisms in African-American and Caucasian populations
    Cornelia M Ulrich
    Fred Hutchinson Cancer Research Center, Cancer Prevention Research Program, University of Washington, Seattle, WA 98109 1024, USA
    Hum Mutat 20:409-10. 2002
    ..More detailed phenotypic characterizations of these COX1 polymorphisms remain to be undertaken...
  53. ncbi request reprint Meta-analysis of loci associated with age at natural menopause in African-American women
    Christina T L Chen
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Hum Mol Genet 23:3327-42. 2014
    ..We provide evidence that genetic variants influencing reproductive traits identified in European populations are also important in women of African ancestry residing in USA...
  54. pmc Recombination as a mechanism for sporadic mutation in the surfactant protein-C gene
    Amy D McBee
    Division of Newborn Medicine, Edward Mallinckrodt Department of Pediatrics, Washington University School of Medicine, St Louis, Missouri, USA
    Pediatr Pulmonol 43:443-50. 2008
    ..To determine haplotype background of common mutations in the genes encoding surfactant proteins B and C (SFTPB and SFTPC) and to assess recombination in SFTPC...
  55. ncbi request reprint The effects of scale: variation in the APOA1/C3/A4/A5 gene cluster
    Stephanie M Fullerton
    Department of Anthropology, Penn State University, 409 Carpenter Bldg, University Park, PA 16802, USA
    Hum Genet 115:36-56. 2004
    ..The implications of these findings for other haplotype-based descriptions of human variation are discussed...
  56. ncbi request reprint Association of polymorphisms in the CRP gene with circulating C-reactive protein levels and cardiovascular events
    Leslie A Lange
    Department of Genetics, University of North Carolina, Chapel Hill, NC 27599 7264, USA
    JAMA 296:2703-11. 2006
    ..C-reactive protein (CRP) is an inflammation protein that may play a role in the pathogenesis of cardiovascular disease (CVD)...
  57. ncbi request reprint Agnosticism and equity in genome-wide association studies
    Christopher S Carlson
    Nat Genet 38:605-6. 2006
  58. ncbi request reprint Comment on 'Discrepancies in dbSNP confirmations rates and allele frequency distributions from varying genotyping error rates and patterns'
    Christopher S Carlson
    Bioinformatics 21:141-3. 2005
  59. pmc Comprehensive genetic variant discovery in the surfactant protein B gene
    Aaron Hamvas
    Edward Mallinckrodt Department of Pediatrics, Washington University School of Medicine and St Louis Children s Hospital, St Louis, Missouri 63110, USA
    Pediatr Res 62:170-5. 2007
    ....