Steve N Caritis

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. ncbi request reprint A pharmacologic approach to the use of glyburide in pregnancy
    Steve N Caritis
    Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Obstet Gynecol 121:1309-12. 2013
  2. pmc Prevention of preterm birth in triplets using 17 alpha-hydroxyprogesterone caproate: a randomized controlled trial
    Steve N Caritis
    Departments of Obstetrics and Gynecology, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Obstet Gynecol 113:285-92. 2009
  3. pmc Relationship between 17-hydroxyprogesterone caproate concentrations and gestational age at delivery in twin gestation
    Steve N Caritis
    Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, PA
    Am J Obstet Gynecol 207:396.e1-8. 2012
  4. pmc Maternal and neonatal outcomes of repeat cesarean delivery in women with a prior classical versus low transverse uterine incision
    Tiki Bakhshi
    Departments of Obstetrics and Gynecology, The University of Texas Health Science Center at Houston, Houston, Texas, USA
    Am J Perinatol 27:791-6. 2010
  5. pmc Pharmacokinetics of 17-hydroxyprogesterone caproate in multifetal gestation
    Steve N Caritis
    Department of Obstetrics, Gynecology, and Reproductive Sciences, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA
    Am J Obstet Gynecol 205:40.e1-8. 2011
  6. pmc Hepatobiliary disposition of 17-OHPC and taurocholate in fetal human hepatocytes: a comparison with adult human hepatocytes
    Shringi Sharma
    Department of Pharmaceutical Sciences, University of Pittsburgh School of Pharmacy, Pittsburgh, PA, USA
    Drug Metab Dispos 41:296-304. 2013
  7. pmc Pharmacology and placental transport of 17-hydroxyprogesterone caproate in singleton gestation
    Steve N Caritis
    Department of Obstetrics, Gynecology, and Reproductive Sciences, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA
    Am J Obstet Gynecol 207:398.e1-8. 2012
  8. pmc Placental endothelial nitric oxide synthase in multiple and single dose betamethasone exposed pregnancies
    Heather L Mertz
    Departments of Obstetrics and Gynecology, Wake Forest Health Sciences, Winston Salem, NC, USA
    Am J Obstet Gynecol 204:545.e11-6. 2011
  9. pmc Comparison of transverse and vertical skin incision for emergency cesarean delivery
    Blair J Wylie
    Department of Obstetrics, Columbia University, New York, New York, USA
    Obstet Gynecol 115:1134-40. 2010
  10. ncbi request reprint Frequency of and factors associated with severe maternal morbidity
    William A Grobman
    Departments of Obstetrics and Gynecology, Northwestern University, Chicago, Illinois, Case Western Reserve University MetroHealth Medical Center, Cleveland, Ohio, Columbia University, New York, New York, The University of Utah Health Sciences Center, Salt Lake City, Utah, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, The University of Texas Southwestern Medical Center, Dallas, Texas, The University of Pittsburgh, Pittsburgh, Pennsylvania, The Ohio State University, Columbus, Ohio, The University of Alabama at Birmingham, Birmingham, Alabama, The University of Texas Medical Branch, Galveston, Texas, Wayne State University, Detroit, Michigan, Brown University, Providence, Rhode Island, the University of Texas Health Science Center at Houston Children s Memorial Hermann Hospital, Houston, Texas, Oregon Health and Science University, Portland, Oregon, and the Medical University of South Carolina, Charleston, South Carolina the George Washington University Biostatistics Center, Washington, DC and the Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland
    Obstet Gynecol 123:804-10. 2014

Research Grants

Detail Information

Publications71

  1. ncbi request reprint A pharmacologic approach to the use of glyburide in pregnancy
    Steve N Caritis
    Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Obstet Gynecol 121:1309-12. 2013
    ..This commentary provides a pharmacologic basis for altering the glyburide administration regimen. Taking glyburide 1 hour before a meal may improve efficacy in patients with pregnancy-related hyperglycemia...
  2. pmc Prevention of preterm birth in triplets using 17 alpha-hydroxyprogesterone caproate: a randomized controlled trial
    Steve N Caritis
    Departments of Obstetrics and Gynecology, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Obstet Gynecol 113:285-92. 2009
    ..To assess whether 17 alpha-hydroxyprogesterone caproate reduces the rate of preterm birth in women carrying triplets...
  3. pmc Relationship between 17-hydroxyprogesterone caproate concentrations and gestational age at delivery in twin gestation
    Steve N Caritis
    Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, PA
    Am J Obstet Gynecol 207:396.e1-8. 2012
    ..We sought to evaluate in women with twin gestation the relationship between 17-hydroxyprogesterone caproate (17-OHPC) concentration and gestational age at delivery and select biomarkers of potential pathways of drug action...
  4. pmc Maternal and neonatal outcomes of repeat cesarean delivery in women with a prior classical versus low transverse uterine incision
    Tiki Bakhshi
    Departments of Obstetrics and Gynecology, The University of Texas Health Science Center at Houston, Houston, Texas, USA
    Am J Perinatol 27:791-6. 2010
    ..Uterine dehiscence was present at repeat CD in 2.46% of women with a prior classical CD. However, major maternal morbidities were similar to those with a prior low transverse CD...
  5. pmc Pharmacokinetics of 17-hydroxyprogesterone caproate in multifetal gestation
    Steve N Caritis
    Department of Obstetrics, Gynecology, and Reproductive Sciences, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA
    Am J Obstet Gynecol 205:40.e1-8. 2011
    ..The purpose of this study was to define the pharmacokinetic parameters of 17-hydroxyprogesterone caproate (17-OHPC) in multifetal gestation...
  6. pmc Hepatobiliary disposition of 17-OHPC and taurocholate in fetal human hepatocytes: a comparison with adult human hepatocytes
    Shringi Sharma
    Department of Pharmaceutical Sciences, University of Pittsburgh School of Pharmacy, Pittsburgh, PA, USA
    Drug Metab Dispos 41:296-304. 2013
    ..With the exception of ABCB4, all transporters examined were expressed, albeit at lower mRNA levels in fetal hepatocytes compared with adults...
  7. pmc Pharmacology and placental transport of 17-hydroxyprogesterone caproate in singleton gestation
    Steve N Caritis
    Department of Obstetrics, Gynecology, and Reproductive Sciences, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA
    Am J Obstet Gynecol 207:398.e1-8. 2012
    ..The purpose of this study was to estimate pharmacokinetic parameters and to evaluate placental transport of 17-hydroxyprogesterone caproate (17-OHPC) in singleton gestation...
  8. pmc Placental endothelial nitric oxide synthase in multiple and single dose betamethasone exposed pregnancies
    Heather L Mertz
    Departments of Obstetrics and Gynecology, Wake Forest Health Sciences, Winston Salem, NC, USA
    Am J Obstet Gynecol 204:545.e11-6. 2011
    ..To compare endothelial nitric oxide synthase expression and capillary density (CDS) in placentas exposed to single or multiple courses of betamethasone...
  9. pmc Comparison of transverse and vertical skin incision for emergency cesarean delivery
    Blair J Wylie
    Department of Obstetrics, Columbia University, New York, New York, USA
    Obstet Gynecol 115:1134-40. 2010
    ..To compare incision-to-delivery intervals and related maternal and neonatal outcomes by skin incision in primary and repeat emergent cesarean deliveries...
  10. ncbi request reprint Frequency of and factors associated with severe maternal morbidity
    William A Grobman
    Departments of Obstetrics and Gynecology, Northwestern University, Chicago, Illinois, Case Western Reserve University MetroHealth Medical Center, Cleveland, Ohio, Columbia University, New York, New York, The University of Utah Health Sciences Center, Salt Lake City, Utah, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, The University of Texas Southwestern Medical Center, Dallas, Texas, The University of Pittsburgh, Pittsburgh, Pennsylvania, The Ohio State University, Columbus, Ohio, The University of Alabama at Birmingham, Birmingham, Alabama, The University of Texas Medical Branch, Galveston, Texas, Wayne State University, Detroit, Michigan, Brown University, Providence, Rhode Island, the University of Texas Health Science Center at Houston Children s Memorial Hermann Hospital, Houston, Texas, Oregon Health and Science University, Portland, Oregon, and the Medical University of South Carolina, Charleston, South Carolina the George Washington University Biostatistics Center, Washington, DC and the Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland
    Obstet Gynecol 123:804-10. 2014
    ..To estimate the frequency of severe maternal morbidity, assess its underlying etiologies, and develop a scoring system to predict its occurrence.Supplemental Digital Content is Available in the Text...
  11. ncbi request reprint Blood transfusion and cesarean delivery
    Dwight J Rouse
    Department of Obstetrics, The University of Alabama at Birmingham, Birmingham, Alabama 35249 7333, USA
    Obstet Gynecol 108:891-7. 2006
    ..To evaluate risks for intraoperative or postoperative packed red blood cell transfusion in women who underwent cesarean delivery...
  12. pmc Quality assessment of compounded 17-hydroxyprogesterone caproate
    Justine Chang
    Department of Obstetrics, Gynecology and Reproductive Sciences, School of Medicine, University of Pittsburgh, Pittsburgh, PA
    Am J Obstet Gynecol 210:47.e1-7. 2014
    ..The purpose of this study was to evaluate the quality of compounded 17-hydroxyprogesterone caproate (17-OHPC)...
  13. ncbi request reprint Maternal and fetal Toll-like receptor 4 genotype and chorionic plate inflammatory lesions
    Hyagriv N Simhan
    Division of Maternal Fetal Medicine, Magee Womens Research Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Am J Obstet Gynecol 199:400.e1-4. 2008
    ..The objective of the study was to explore the relation between maternal and fetal genetic variation in Toll-like receptor 4 (TLR4) and chorionic plate inflammation..
  14. pmc The effect of maternal body mass index on neonatal outcome in women receiving a single course of antenatal corticosteroids
    Jason N Hashima
    Department of Obstetrics, Oregon Health and Science University, Portland, OR, USA
    Am J Obstet Gynecol 202:263.e1-5. 2010
    ..The aim of this study was to determine the effect of maternal body mass index on the incidence of neonatal prematurity morbidities in those who receive corticosteroids...
  15. pmc Qualitative and quantitative measures of various compounded formulations of 17-alpha hydroxyprogesterone caproate
    Steve N Caritis
    Department of Obstetrics, Gynecology, and Reproductive Sciences, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA
    Am J Obstet Gynecol 208:470.e1-5. 2013
    ..The objective of this study was to assess the stability and the microbiologic and pyrogen status of 17-OHPC formulations under various compounding and dispensing conditions...
  16. pmc Metabolism of 17alpha-hydroxyprogesterone caproate, an agent for preventing preterm birth, by fetal hepatocytes
    Shringi Sharma
    Department of Pathology, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Drug Metab Dispos 38:723-7. 2010
    ..In summary, this study demonstrates that fetal hepatocytes and, in particular, the fetal form of CYP3A (i.e., CYP3A7) can metabolize 17-OHPC...
  17. ncbi request reprint Elevated vaginal pH and neutrophils are associated strongly with early spontaneous preterm birth
    Hyagriv N Simhan
    Department of Obstetrics, Gynecology, and Reproductive Sciences, Magee Womens Research Institute, University of Pittsburgh School of Medicine, PA, USA
    Am J Obstet Gynecol 189:1150-4. 2003
    ..All women were tested for sexually transmitted infections and vaginal pH. Gram-stained smears were used for the detection of neutrophils...
  18. ncbi request reprint Decreased cervical proinflammatory cytokines permit subsequent upper genital tract infection during pregnancy
    Hyagriv N Simhan
    Division of Maternal Fetal Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh School of Medicine, Magee Womens Research Institute, Pittsburgh, PA 15213, USA
    Am J Obstet Gynecol 189:560-7. 2003
    ....
  19. ncbi request reprint The vaginal inflammatory milieu and the risk of early premature preterm rupture of membranes
    Hyagriv N Simhan
    Department of Obstetrics, Gynecology, and Reproductive Sciences, Magee Womens Research Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Am J Obstet Gynecol 192:213-8. 2005
    ..The purpose of this study was to determine the association of vaginal pH > or =5.0 and vaginal neutrophils >5 per oil field with preterm rupture of membranes (PPROM)...
  20. ncbi request reprint Tumor necrosis factor-alpha promoter gene polymorphism -308 and chorioamnionitis
    Hyagriv N Simhan
    Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Obstet Gynecol 102:162-6. 2003
    ..The TNFA2 allele is associated with increased production of tumor necrosis factor alpha. The purpose of this study is to assess the relationship between carriage of the TNFA2 allele and clinical chorioamnionitis...
  21. ncbi request reprint Pharmacologic inhibition of preterm labor
    Arun Jeyabalan
    Department of Obstetrics, Gynecology and Reproductive Sciences, Division of Maternal Fetal Medicine, University of Pittsburgh School of Medicine, Magee Womens Hospital, Pittsburgh, Pennsylvania 15213, USA
    Clin Obstet Gynecol 45:99-113. 2002
  22. ncbi request reprint Interleukin-6 promoter -174 polymorphism and spontaneous preterm birth
    Hyagriv N Simhan
    University of Pittsburgh School of Medicine, Department of Obstetrics, Magee Womens Research Institute, Pittsburgh, PA, USA
    Am J Obstet Gynecol 189:915-8. 2003
    ..We assessed the relationship between interleukin-6 (IL-6) promoter -174 polymorphism and spontaneous preterm birth (sPTB) less than 34 weeks and the relationship of polymorphism status with race...
  23. ncbi request reprint Effect of excess gestational weight gain on pregnancy outcomes in women with type 1 diabetes
    Christina M Scifres
    Department of Obstetrics, Gynecology and Reproductive Sciences, Magee Women s Research Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania
    Obstet Gynecol 123:1295-302. 2014
    ..To evaluate the prevalence and clinical effects of excess gestational weight gain on birth weight and other pregnancy outcomes in women with type 1 diabetes...
  24. pmc A sensitive and specific CYP cocktail assay for the simultaneous assessment of human cytochrome P450 activities in primary cultures of human hepatocytes using LC-MS/MS
    Venkateswaran C Pillai
    Department of Pharmaceutical Sciences, University of Pittsburgh School of Pharmacy, Pittsburgh, PA, USA
    J Pharm Biomed Anal 74:126-32. 2013
    ..Therefore, the final CYP cocktail assay consisting of five probes provides a robust method to simultaneously measure activities of CYP1A2, CYP2C9, CYP2C19, CYP2D6 and CYP3A4/5 in primary cultures of human hepatocytes...
  25. pmc Pharmacokinetics of oseltamivir among pregnant and nonpregnant women
    Richard H Beigi
    Division of Reproductive Infectious Diseases, Department of Obstetrics, Gynecology, and Reproductive Sciences, Magee Women s Hospital, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Am J Obstet Gynecol 204:S84-8. 2011
    ..Pregnancy produces lower systemic levels of oseltamivir carboxylate. Increasing the dose and/or dosing frequency of oseltamivir during pregnancy may be necessary to achieve comparable exposure in pregnant and nonpregnant women...
  26. ncbi request reprint Prevention of preterm delivery
    Hyagriv N Simhan
    Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, USA
    N Engl J Med 357:477-87. 2007
  27. pmc Human decidual cell Toll-like receptor signaling in response to endotoxin: the effect of progestins
    Hyagriv N Simhan
    Division of Maternal Fetal Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, Magee Womens Research Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Am J Obstet Gynecol 198:119.e1-4. 2008
    ..The purpose of this study was to determine whether progesterone, 17-alpha-hydroxyprogesterone, and 17-alpha hydroxyprogesterone caproate modulate the Toll-like receptor (TLR) pathway in the response of decidua to lipopolysaccharide...
  28. ncbi request reprint Cervical anti-inflammatory cytokine concentrations among first-trimester pregnant smokers
    Hyagriv N Simhan
    Division of Maternal Fetal Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh School of Medicine, Magee Womens Research Institute, Pittsburgh, PA, USA
    Am J Obstet Gynecol 193:1999-2003. 2005
    ..We examined the impact of cigarette smoking in pregnancy on the detection of the 3 most important anti-inflammatory cytokines (interleukin-4, -10, and -13) in the cervix...
  29. ncbi request reprint The Maternal-Fetal Medicine Unit cesarean registry: trial of labor with a twin gestation
    Michael W Varner
    Department of Obstetrics, University of Utah, Salt Lake City 84132, USA
    Am J Obstet Gynecol 193:135-40. 2005
    ..The purpose of this study was to identify the success rates and risks in women with a twin pregnancy who attempt a trial of labor after cesarean delivery...
  30. ncbi request reprint Outcomes of induction of labor after one prior cesarean
    William A Grobman
    Departments of Obstetrics and Gynecology at Northwestern University, 333 East Superior Street, Chicago, IL 60611, USA
    Obstet Gynecol 109:262-9. 2007
    ..To compare pregnancy outcomes in women with one prior low-transverse cesarean delivery after induction of labor with pregnancy outcomes after spontaneous labor...
  31. ncbi request reprint The Maternal-Fetal Medicine Units cesarean registry: chorioamnionitis at term and its duration-relationship to outcomes
    Dwight J Rouse
    Department of Obstetrics and Gynecology, Center for Research in Women s Health, University of Alabama at Birmingham, 35249 7333, USA
    Am J Obstet Gynecol 191:211-6. 2004
    ..The purpose of this study was to evaluate the relationship between chorioamnionitis and its duration to adverse maternal, fetal, and neonatal outcomes...
  32. ncbi request reprint Frequency of uterine contractions in asymptomatic pregnant women with or without a short cervix on transvaginal ultrasound scan
    Vincenzo Berghella
    Departments of Obstetrics and Gynecology at Jefferson Medical College of Thomas Jefferson University, Philadelphia, PA, USA
    Am J Obstet Gynecol 191:1253-6. 2004
    ....
  33. ncbi request reprint Frequency of uterine contractions and the risk of spontaneous preterm delivery
    Jay D Iams
    Department of Obstetrics and Gynecology at Ohio State University, Columbus 43210 1228, USA
    N Engl J Med 346:250-5. 2002
    ..The measurement of the frequency of uterine contractions has not been useful for reducing the rate of preterm delivery in randomized trials. Nonetheless, ambulatory monitoring of contractions continues to be used in clinical practice...
  34. ncbi request reprint Association of obesity with pulmonary and nonpulmonary complications of pregnancy in asthmatic women
    Israel Hendler
    Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Hutzel Hospital Wayne State University, Detroit, Michigan 48201, USA
    Obstet Gynecol 108:77-82. 2006
    ..To evaluate whether maternal obesity is associated with pulmonary and nonpulmonary pregnancy complications in asthmatic women...
  35. ncbi request reprint Previous preterm cesarean delivery and risk of subsequent uterine rupture
    Anthony C Sciscione
    Department of Obstetrics and Gynecology at Christiana Care Health System, Newark, Delaware 19713, USA
    Obstet Gynecol 111:648-53. 2008
    ..To determine if women with a history of a previous preterm cesarean delivery experienced an increased risk of subsequent uterine rupture compared with women who had a previous nonclassic term cesarean delivery...
  36. ncbi request reprint Uterine contraction frequency before and after successful tocolytic therapy for preterm uterine contractions
    Roger B Newman
    Department of Obstetrics and Gynecology, Medical University of South Carolina, 96 Jonathan Lucas Street, Suite 634, P O Box 250619, Charleston, SC 29425, USA
    J Reprod Med 48:843-9. 2003
    ..To examine the association between prelabor uterine contraction frequency (UCF) and the success of tocolytic therapy for preterm labor (PTL)...
  37. ncbi request reprint Spirometry is related to perinatal outcomes in pregnant women with asthma
    Michael Schatz
    Department of Allergy, Kaiser Permanente, San Diego, CA, USA
    Am J Obstet Gynecol 194:120-6. 2006
    ..The purpose of this study was to test the hypothesis that maternal asthma symptoms and pulmonary function are related to adverse perinatal outcomes...
  38. ncbi request reprint The preterm prediction study: elevated cervical ferritin levels at 22 to 24 weeks of gestation are associated with spontaneous preterm delivery in asymptomatic women
    Patrick S Ramsey
    National Institute of Child Health and Human Development, Maternal Fetal Medicine Units Network, USA
    Am J Obstet Gynecol 186:458-63. 2002
    ..Our objective was to determine whether elevated levels of ferritin in the genital tract may be a potent marker to identify patients at risk for spontaneous preterm delivery...
  39. ncbi request reprint Midpregnancy genitourinary tract infection with Chlamydia trachomatis: association with subsequent preterm delivery in women with bacterial vaginosis and Trichomonas vaginalis
    William W Andrews
    Department of Obstetrics and Gynecology, University of Alabama, Birmingham, AL, USA
    Am J Obstet Gynecol 194:493-500. 2006
    ..The objective of the study was to estimate whether midpregnancy genitourinary tract infection with Chlamydia trachomatis is associated with an increased risk of subsequent preterm delivery...
  40. ncbi request reprint The Preterm Prediction Study: the value of serum alkaline phosphatase, alpha-fetoprotein, plasma corticotropin-releasing hormone, and other serum markers for the prediction of spontaneous preterm birth
    Atef H Moawad
    National Institute of Child Health and Human Development Maternal Fetal Medicine Unit Network, USA
    Am J Obstet Gynecol 186:990-6. 2002
    ..We investigated the relationship between 8 potential blood markers and subsequent spontaneous preterm birth in asymptomatic pregnant women...
  41. ncbi request reprint The MFMU Cesarean Registry: factors affecting the success of trial of labor after previous cesarean delivery
    Mark B Landon
    Department of Obstetrics and Gynecology at The Ohio State University College of Medicine and Public Health, Columbus, OH 43210 1228, USA
    Am J Obstet Gynecol 193:1016-23. 2005
    ..The purpose of this study was to determine which factors influence the likelihood of successful trial of labor (TOL) after 1 previous cesarean delivery (CD)...
  42. ncbi request reprint Differences in inflammatory cytokine and Toll-like receptor genes and bacterial vaginosis in pregnancy
    Alice R Goepfert
    Department of Obstetrics and Gynecology, The University of Alabama, Birmingham, AL, USA
    Am J Obstet Gynecol 193:1478-85. 2005
    ..This study was undertaken to estimate the frequency of inflammatory cytokine and Toll-like receptor gene polymorphisms in women with and without bacterial vaginosis (BV) in pregnancy...
  43. pmc Cesarean delivery for the second twin
    James M Alexander
    Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX 75235 9032, USA
    Obstet Gynecol 112:748-52. 2008
    ..To examine maternal and infant outcomes after a vaginal delivery of twin A and a cesarean delivery of twin B, and to identify whether the second twin experienced increased short-term morbidity as part of a combined route of delivery...
  44. pmc A randomized, controlled trial of magnesium sulfate for the prevention of cerebral palsy
    Dwight J Rouse
    University of Alabama at Birmingham, Birmingham, USA
    N Engl J Med 359:895-905. 2008
    ..Research suggests that fetal exposure to magnesium sulfate before preterm birth might reduce the risk of cerebral palsy...
  45. ncbi request reprint The relationship of asthma medication use to perinatal outcomes
    Michael Schatz
    Allergy Department, Kaiser Permanente Medical Center, 7060 Clairemont Mesa Boulevard, San Diego, CA 92111, USA
    J Allergy Clin Immunol 113:1040-5. 2004
    ..Maternal asthma has been reported to increase the risk of preeclampsia, preterm deliveries, and lower-birth-weight infants, but the mechanisms of this effect are not defined...
  46. ncbi request reprint Randomized trial of inhaled beclomethasone dipropionate versus theophylline for moderate asthma during pregnancy
    Mitchell P Dombrowski
    Department of Obstetrics and Gynecology, Wayne State University, Detroit, Mich, USA
    Am J Obstet Gynecol 190:737-44. 2004
    ..This study was undertaken to compare the efficacy of inhaled beclomethasone dipropionate to oral theophylline for the prevention of asthma exacerbation(s) requiring medical intervention...
  47. ncbi request reprint Asthma during pregnancy
    Mitchell P Dombrowski
    Departments of Obstetrics and Gynecology at Wayne State University, Detroit, Michigan 48236, USA
    Obstet Gynecol 103:5-12. 2004
    ..The primary hypothesis was that moderate or severe asthmatics would have an increased incidence of delivery at <32 weeks of gestation compared with nonasthmatic controls...
  48. ncbi request reprint Plasma CRH measurement at 16 to 20 weeks' gestation does not predict preterm delivery in women at high-risk for preterm delivery
    Baha Sibai
    Department of Obstetrics and Gynecology, University of Cincinnati School of Medicine, Cincinnati, OH 45267, USA
    Am J Obstet Gynecol 193:1181-6. 2005
    ..The purpose of this study was to examine the utility of a single second-trimester plasma corticotropin-releasing hormone measurement as a marker for preterm delivery in women at high risk for preterm delivery...
  49. ncbi request reprint Trial of labor or repeat cesarean delivery in women with morbid obesity and previous cesarean delivery
    Judith U Hibbard
    Department of Obstetrics and Gynecology, University of Chicago, Chicago, Illinois 60612, USA
    Obstet Gynecol 108:125-33. 2006
    ....
  50. ncbi request reprint Prevention of recurrent preterm delivery by 17 alpha-hydroxyprogesterone caproate
    Paul J Meis
    Department of Obstetrics and Gynecology, Wake Forest University, Winston Salem, NC 27157, USA
    N Engl J Med 348:2379-85. 2003
    ..The results of several small trials have suggested that 17 alpha-hydroxyprogesterone caproate (17P) may reduce the risk of preterm delivery...
  51. pmc Bone metabolism in pregnant women exposed to single compared with multiple courses of corticosteroids
    Mary A Carroll
    Department of Obstetrics and Gynecology, University of Texas Houston, Houston, Texas 77030, USA
    Obstet Gynecol 111:1352-8. 2008
    ..To compare markers of maternal bone metabolism between women who received a single compared with multiple courses of antenatal corticosteroids...
  52. ncbi request reprint Pregnancy outcomes for women with placenta previa in relation to the number of prior cesarean deliveries
    William A Grobman
    Department of Obstetrics and Gynecology at Northwestern University, Chicago, Illinois, USA
    Obstet Gynecol 110:1249-55. 2007
    ..To estimate the association between the number of prior cesarean deliveries and pregnancy outcomes among women with placenta previa...
  53. ncbi request reprint Decision-to-incision times and maternal and infant outcomes
    Steven L Bloom
    Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    Obstet Gynecol 108:6-11. 2006
    ....
  54. ncbi request reprint A prospective masked observational study of uterine contraction frequency in twins
    Roger B Newman
    Department of Obstetrics and Gynecology, Medical University of South Carolina, Charleston, SC, USA
    Am J Obstet Gynecol 195:1564-70. 2006
    ..This study was undertaken to compare uterine contraction frequency in twins versus singletons and to determine if contraction frequency can be an efficient predictor of spontaneous preterm birth in twin gestations...
  55. ncbi request reprint Maternal morbidity associated with multiple repeat cesarean deliveries
    Robert M Silver
    Department of Obstetrics and Gynecology, University of Utah School of Medicine, Salt Lake City, Utah 84132, USA
    Obstet Gynecol 107:1226-32. 2006
    ..Our objective was to estimate the magnitude of increased maternal morbidity associated with increasing number of cesarean deliveries...
  56. ncbi request reprint Antioxidants and the prevention of preeclampsia--unresolved issues
    Arun Jeyabalan
    N Engl J Med 354:1841-3. 2006
  57. ncbi request reprint Are women with recurrent spontaneous preterm births different from those without such history?
    Brian M Mercer
    Department of Reproductive Biology, Case Western Reserve University, Cleveland, OH, USA
    Am J Obstet Gynecol 194:1176-84; discussion 1184-5. 2006
    ....
  58. ncbi request reprint Progesterone for prevention of recurrent preterm birth: impact of gestational age at previous delivery
    Catherine Y Spong
    National Institute of Child Health and Human Development, Bethesda, MD, USA
    Am J Obstet Gynecol 193:1127-31. 2005
    ..We hypothesized that treatment with 17-OHP caproate is more effective in prolonging pregnancy depending on the gestational age of the earliest previous preterm birth (20-27.9, 28-33.9 vs 34-36.9 weeks)...
  59. ncbi request reprint Complications of anesthesia for cesarean delivery
    Steven L Bloom
    Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9032, USA
    Obstet Gynecol 106:281-7. 2005
    ....
  60. ncbi request reprint The Preterm Prediction Study: association between maternal body mass index and spontaneous and indicated preterm birth
    Israel Hendler
    National Institute of Child Health and Human Development, Maternal Fetal Medicine Units Network, National Institutes of Health, Bethesda, MD, USA
    Am J Obstet Gynecol 192:882-6. 2005
    ..The purpose of this study was to evaluate the relationship between prepregnancy maternal body mass index and spontaneous preterm birth and indicated preterm birth...
  61. ncbi request reprint Risk of uterine rupture with a trial of labor in women with multiple and single prior cesarean delivery
    Mark B Landon
    Department of Obstetrics and Gynecology, Ohio State University, Columbus, Ohio, USA
    Obstet Gynecol 108:12-20. 2006
    ..To determine whether the risk for uterine rupture is increased in women attempting vaginal birth after multiple cesarean deliveries...
  62. ncbi request reprint Single versus weekly courses of antenatal corticosteroids: evaluation of safety and efficacy
    Ronald J Wapner
    Department of Obstetrics and Gynecology, Drexel University College of Medicine, Philadelphia, PA, USA
    Am J Obstet Gynecol 195:633-42. 2006
    ..The purpose of this study was to determine if weekly corticosteroids improve neonatal outcome without undue harm...
  63. ncbi request reprint A trial of 17 alpha-hydroxyprogesterone caproate to prevent prematurity in twins
    Dwight J Rouse
    Department of Obstetrics and Gynecology, Center for Women s Reproductive Health, University of Alabama at Birmingham, Birmingham 35249 7333, USA
    N Engl J Med 357:454-61. 2007
    ..In singleton gestations, 17 alpha-hydroxyprogesterone caproate (17P) has been shown to reduce the rate of recurrent preterm birth. This study was undertaken to evaluate whether 17P would reduce the rate of preterm birth in twin gestations...
  64. ncbi request reprint Perioperative morbidity and mortality among human immunodeficiency virus infected women undergoing cesarean delivery
    Judette Louis
    Wayne State University, Detroit, MI, USA
    Obstet Gynecol 110:385-90. 2007
    ..To determine whether human immunodeficiency virus (HIV)-infected women have a higher rate of postcesarean morbidity and mortality compared with women without HIV infection...
  65. ncbi request reprint Comparison of maternal and infant outcomes from primary cesarean delivery during the second compared with first stage of labor
    James M Alexander
    Department of Obstetrics and Gynecology at the University of Texas Southwestern Medical Center, Dallas, Texas 75235 9032, USA
    Obstet Gynecol 109:917-21. 2007
    ..To compare maternal and neonatal outcomes when primary cesarean delivery is performed in the second stage of labor compared with the first stage...
  66. ncbi request reprint Development of a nomogram for prediction of vaginal birth after cesarean delivery
    William A Grobman
    Department of Obstetrics and Gynecology at Northwestern University, Chicago, Illinois 60611, USA
    Obstet Gynecol 109:806-12. 2007
    ..To develop a model based on factors available at the first prenatal visit that predicts chance of successful vaginal birth after cesarean delivery (VBAC) for individual patients who undergo a trial of labor...
  67. ncbi request reprint Fetal pulse oximetry and cesarean delivery
    Steven L Bloom
    University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    N Engl J Med 355:2195-202. 2006
    ..Knowledge of fetal oxygen saturation, as an adjunct to electronic fetal monitoring, may be associated with a significant change in the rate of cesarean deliveries or the infant's condition at birth...
  68. ncbi request reprint Maternal and perinatal outcomes associated with a trial of labor after prior cesarean delivery
    Mark B Landon
    Department of Obstetrics and Gynecology at Ohio State University, College of Medicine and Public Health, Columbus 43210 1228, USA
    N Engl J Med 351:2581-9. 2004
    ..The absolute and relative risks associated with a trial of labor in women with a history of cesarean delivery, as compared with elective repeated cesarean delivery without labor, are uncertain...
  69. ncbi request reprint Fetal injury associated with cesarean delivery
    James M Alexander
    Department of Obstetrics at the University of Texas Southwestern Medical Center, Dallas, Texas 75235 9032, USA
    Obstet Gynecol 108:885-90. 2006
    ..To describe the incidence and type of fetal injury identified in women undergoing cesarean delivery...
  70. ncbi request reprint The MFMU Cesarean Registry: impact of fetal size on trial of labor success for patients with previous cesarean for dystocia
    Alan M Peaceman
    Department of Obstetrics and Gynecology, Northwestern University, Chicago, IL, USA
    Am J Obstet Gynecol 195:1127-31. 2006
    ..The purpose of this study was to determine the influence of change in infant birth weight between pregnancies on the outcome of a trial of labor for women whose first cesarean delivery was performed for dystocia...
  71. ncbi request reprint Spontaneous resolution of asymptomatic Chlamydia trachomatis in pregnancy
    Jeanne S Sheffield
    Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center at Dallas, Texas 75390 9032, USA
    Obstet Gynecol 105:557-62. 2005
    ..We sought to estimate the rate of spontaneous resolution of asymptomatic Chlamydia trachomatis in pregnancy and to evaluate factors associated with its resolution...

Research Grants9

  1. COOPERATIVE MULTICENTER MATERNAL-FETAL MEDICINE UNITS N*
    Steve Caritis; Fiscal Year: 2003
    ..This wide diversity of patients makes our institution particularly well suited for the performance of clinical trials. ..
  2. Pregnancy and Drug Metabolizing Enzymes and Transporters
    Steve Caritis; Fiscal Year: 2004
    ..The leadership has experience in collaborative endeavors and is prepared to cooperate with other OPRUs to conduct collaborative research. ..
  3. NICHD Maternal Fetal Medicine Units Network
    Steve Caritis; Fiscal Year: 2006
    ..The Network has shown repeatedly that meaningful research can be performed with pregnant women and that that research can be undertaken safely. ..
  4. NICHD Maternal Fetal Medicine Units Network
    Steve Caritis; Fiscal Year: 2007
    ..The Network has shown repeatedly that meaningful research can be performed with pregnant women and that that research can be undertaken safely. ..
  5. Pregnancy and Drug Metabolizing Enzymes and Transporters
    Steve Caritis; Fiscal Year: 2007
    ..The leadership has experience in collaborative endeavors and is prepared to cooperate with other OPRUs to conduct collaborative research. ..
  6. Pregnancy and Drug Metabolizing Enzymes and Transporters
    Steve Caritis; Fiscal Year: 2006
    ..The leadership has experience in collaborative endeavors and is prepared to cooperate with other OPRUs to conduct collaborative research. ..