H V Carey

Summary

Affiliation: University of Wisconsin
Country: USA

Publications

  1. ncbi request reprint Hibernation induces oxidative stress and activation of NK-kappaB in ground squirrel intestine
    H V Carey
    Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin, 53706, USA
    J Comp Physiol B 170:551-9. 2000
  2. ncbi request reprint Involvement of PI 3-kinase in IGF-I stimulation of jejunal Na+-K+-ATPase activity and nutrient absorption
    A N Alexander
    Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin, 2015 Linden Dr West, Madison, WI 53706, USA
    Am J Physiol Gastrointest Liver Physiol 280:G222-8. 2001
  3. ncbi request reprint Hibernation induces glutathione redox imbalance in ground squirrel intestine
    H V Carey
    Department of Comparative Biosciences, University of Wisconsin School of Veterinary Medicine, 2015 Linden Dr West, Madison, WI 53076, USA
    J Comp Physiol B 173:269-76. 2003
  4. ncbi request reprint Mammalian hibernation: cellular and molecular responses to depressed metabolism and low temperature
    Hannah V Carey
    Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI 53706, USA
    Physiol Rev 83:1153-81. 2003
  5. pmc Upregulation of AMPK during cold exposure occurs via distinct mechanisms in brown and white adipose tissue of the mouse
    Jacob D Mulligan
    Department of Medicine, University of Wisconsin, Madison, WI 53706, USA
    J Physiol 580:677-84. 2007
  6. ncbi request reprint Hibernation enhances D-glucose uptake by intestinal brush border membrane vesicles in ground squirrels
    H V Carey
    Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin, Madison 53706, USA
    J Comp Physiol B 166:254-61. 1996
  7. ncbi request reprint Natural resistance to liver cold ischemia-reperfusion injury associated with the hibernation phenotype
    Susanne L Lindell
    Department of Comparative Biosciences, University of Wisconsin, 2015 Linden Dr, Madison WI 53706, USA
    Am J Physiol Gastrointest Liver Physiol 288:G473-80. 2005
  8. pmc Hibernation induces pentobarbital insensitivity in medulla but not cortex
    Keith B Hengen
    School of Veterinary Medicine, University of Wisconsin, Madison, Madison, Wisconsin 53706, USA
    Am J Physiol Regul Integr Comp Physiol 297:R1028-36. 2009
  9. doi request reprint Analysis of the hibernation cycle using LC-MS-based metabolomics in ground squirrel liver
    Clark J Nelson
    Department of Comparative Biosciences, University of Wisconsin School of Veterinary Medicine, Madison, Wisconsin 53706, USA
    Physiol Genomics 37:43-51. 2009
  10. doi request reprint Identification of qRT-PCR reference genes for analysis of opioid gene expression in a hibernator
    Jessica P Otis
    Department of Comparative Biosciences, University of Wisconsin Madison, School of Veterinary Medicine, 2015 Linden Dr, Madison, WI 53706, USA
    J Comp Physiol B 180:619-29. 2010

Collaborators

  • S L Martin
  • Matthew T Andrews
  • T Y Aw
  • KURT SAUPE
  • STEPHEN MARK JOHNSON
  • Mathew Jones
  • Natalie J Serkova
  • Jessica P Otis
  • Clark J Nelson
  • Courtney C Kurtz
  • Susanne L Lindell
  • Keith B Hengen
  • Jacob D Mulligan
  • Karen A Cloud-Hansen
  • Martin J Mangino
  • Courtney C Fleck
  • Andreas Balslev-Clausen
  • Andrew N Alexander
  • A N Alexander
  • Laynez W Ackermann
  • Gerene M Denning
  • Mary Behan
  • Asensio A Gonzalez
  • Annette M Stewart
  • Katrina M Villiard
  • Jo Handelsman
  • Timothy M Piazza
  • James H Southard
  • Jose R Torrealba
  • Shawna L Klahn
  • Julia M McCarthy

Detail Information

Publications19

  1. ncbi request reprint Hibernation induces oxidative stress and activation of NK-kappaB in ground squirrel intestine
    H V Carey
    Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin, 53706, USA
    J Comp Physiol B 170:551-9. 2000
    ....
  2. ncbi request reprint Involvement of PI 3-kinase in IGF-I stimulation of jejunal Na+-K+-ATPase activity and nutrient absorption
    A N Alexander
    Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin, 2015 Linden Dr West, Madison, WI 53706, USA
    Am J Physiol Gastrointest Liver Physiol 280:G222-8. 2001
    ..The results suggest that the effect of IGF-I on jejunal ion and nutrient transport involves activation of PI 3-kinase and stimulation of Na+-K+-ATPase activity in enterocytes...
  3. ncbi request reprint Hibernation induces glutathione redox imbalance in ground squirrel intestine
    H V Carey
    Department of Comparative Biosciences, University of Wisconsin School of Veterinary Medicine, 2015 Linden Dr West, Madison, WI 53076, USA
    J Comp Physiol B 173:269-76. 2003
    ....
  4. ncbi request reprint Mammalian hibernation: cellular and molecular responses to depressed metabolism and low temperature
    Hannah V Carey
    Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI 53706, USA
    Physiol Rev 83:1153-81. 2003
    ....
  5. pmc Upregulation of AMPK during cold exposure occurs via distinct mechanisms in brown and white adipose tissue of the mouse
    Jacob D Mulligan
    Department of Medicine, University of Wisconsin, Madison, WI 53706, USA
    J Physiol 580:677-84. 2007
    ..Our data are consistent with AMPK acting primarily as a regulator of chronic thermogenic potential in brown adipose tissue, and not in the acute activation of non-shivering thermogenesis...
  6. ncbi request reprint Hibernation enhances D-glucose uptake by intestinal brush border membrane vesicles in ground squirrels
    H V Carey
    Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin, Madison 53706, USA
    J Comp Physiol B 166:254-61. 1996
    ....
  7. ncbi request reprint Natural resistance to liver cold ischemia-reperfusion injury associated with the hibernation phenotype
    Susanne L Lindell
    Department of Comparative Biosciences, University of Wisconsin, 2015 Linden Dr, Madison WI 53706, USA
    Am J Physiol Gastrointest Liver Physiol 288:G473-80. 2005
    ..Because hibernation-induced protection is not dependent on animals being in the torpid state, the mechanisms responsible for this effect may provide new strategies for liver preservation in humans...
  8. pmc Hibernation induces pentobarbital insensitivity in medulla but not cortex
    Keith B Hengen
    School of Veterinary Medicine, University of Wisconsin, Madison, Madison, Wisconsin 53706, USA
    Am J Physiol Regul Integr Comp Physiol 297:R1028-36. 2009
    ..We hypothesize that GABA(A) receptors undergo a seasonal modification in subunit composition, such that cardiorespiratory neurons are uniquely unaffected by surges of an endogenous positive allosteric modulator...
  9. doi request reprint Analysis of the hibernation cycle using LC-MS-based metabolomics in ground squirrel liver
    Clark J Nelson
    Department of Comparative Biosciences, University of Wisconsin School of Veterinary Medicine, Madison, Wisconsin 53706, USA
    Physiol Genomics 37:43-51. 2009
    ..The results reveal the dramatic alterations that occur in several classes of metabolites, highlighting the value of metabolomic analyses in deciphering the hibernation phenotype...
  10. doi request reprint Identification of qRT-PCR reference genes for analysis of opioid gene expression in a hibernator
    Jessica P Otis
    Department of Comparative Biosciences, University of Wisconsin Madison, School of Veterinary Medicine, 2015 Linden Dr, Madison, WI 53706, USA
    J Comp Physiol B 180:619-29. 2010
    ..The results support the idea that changes in DOR expression may regulate the level of neuronal activity in brain during the annual hibernation cycle and may contribute to hibernation-associated tissue protection...
  11. ncbi request reprint Seasonal changes in the intestinal immune system of hibernating ground squirrels
    Courtney C Kurtz
    Department of Comparative Biosciences, University of Wisconsin, School of Veterinary Medicine, 2015 Linden Drive, Madison, WI 53706, USA
    Dev Comp Immunol 31:415-28. 2007
    ..The results suggest that modifications of the intestinal immune system during hibernation may help preserve gut integrity throughout the winter fast...
  12. ncbi request reprint Modulation of apoptotic pathways in intestinal mucosa during hibernation
    Courtney C Fleck
    Dept of Comparative Biosciences, University of Wisconsin, 2015 Linden Drive, Madison, WI 53706, USA
    Am J Physiol Regul Integr Comp Physiol 289:R586-R595. 2005
    ..These data provide evidence for enhanced expression of antiapoptotic proteins during hibernation that may promote enterocyte survival in a pro-oxidative, proapoptotic environment...
  13. ncbi request reprint Thirteen-lined ground squirrels (Spermophilus tridecemlineatus) harbor multiantibiotic-resistant bacteria
    Karen A Cloud-Hansen
    Department of Plant Pathology, School of Veterinary Medicine, University of Wisconsin, Madison, WI, USA
    J Am Assoc Lab Anim Sci 46:21-3. 2007
    ..These findings support further study of antibiotic-resistant bacterial populations in wild-caught mammals used as laboratory models...
  14. ncbi request reprint Hibernation reduces pancreatic amylase levels in ground squirrels
    Andreas Balslev-Clausen
    Department of Comparative Biosciences, University of Wisconsin, School of Veterinary Medicine, 2015 Linden Drive, Madison, WI 53706, USA
    Comp Biochem Physiol A Mol Integr Physiol 134:573-8. 2003
    ..The maintenance of basal levels of this key digestive enzyme at approximately 50% of summer values despite the extended winter fast likely facilitates the rapid resumption of digestive function after terminal arousal in the spring...
  15. pmc A role for nuclear receptors in mammalian hibernation
    Clark J Nelson
    Department of Comparative Biosciences, University of Wisconsin School of Veterinary Medicine, Madison, WI 53706, USA
    J Physiol 587:1863-70. 2009
    ....
  16. ncbi request reprint Hibernation confers resistance to intestinal ischemia-reperfusion injury
    Courtney C Kurtz
    Department of Comparative Biosciences, University of Wisconsin School of Veterinary Medicine, Madison, WI, USA
    Am J Physiol Gastrointest Liver Physiol 291:G895-901. 2006
    ..The results suggest that the hibernation phenotype is associated with natural protection against intestinal I/R injury...
  17. ncbi request reprint Quantitative analysis of liver metabolites in three stages of the circannual hibernation cycle in 13-lined ground squirrels by NMR
    Natalie J Serkova
    Department of Anesthesiology, University of Colorado School of Medicine, Aurora, Colorado 80238, USA
    Physiol Genomics 31:15-24. 2007
    ..The torpor-arousal switch is characterized by the accumulation of metabolites of nitrogen (glutamine) and phospholipid (betaine) catabolism in LT with the capacity to act as protective osmolytes...
  18. doi request reprint Proteomic analysis of the winter-protected phenotype of hibernating ground squirrel intestine
    Sandra L Martin
    Department of Cell and Developmental Biology, University of Colorado School of Medicine, Aurora, Colorado 80045, USA
    Am J Physiol Regul Integr Comp Physiol 295:R316-28. 2008
    ..It also reveals the importance of enterocyte maturation in defining the hibernating gut proteome and the role of changing cell populations for the differences between sham and I/R-treated summer animals...
  19. ncbi request reprint Insulin-like growth factor-I stimulates Na+-dependent glutamine absorption in piglet enterocytes
    Andrew N Alexander
    Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin, Madison 53706, USA
    Dig Dis Sci 47:1129-34. 2002
    ..Thus, oral administration of IGF-I stimulates Na+-dependent glutamine absorption in piglet small intestine, an effect that is independent of changes in intestinal mucosal mass...