Anne R Cappola

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. ncbi Insulin-like growth factor I and interleukin-6 contribute synergistically to disability and mortality in older women
    Anne R Cappola
    Department of Medicine, University of Maryland, Baltimore, Maryland 21201, USA
    J Clin Endocrinol Metab 88:2019-25. 2003
  2. pmc DHEAS levels and mortality in disabled older women: the Women's Health and Aging Study I
    Anne R Cappola
    Division of Endocrinology, Diabetes, and Metabolism, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
    J Gerontol A Biol Sci Med Sci 61:957-62. 2006
  3. pmc Thyroid status, cardiovascular risk, and mortality in older adults
    Anne R Cappola
    Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia 19104 6021, USA
    JAMA 295:1033-41. 2006
  4. ncbi Hypothyroidism and atherosclerosis
    Anne R Cappola
    Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, 19104, USA
    J Clin Endocrinol Metab 88:2438-44. 2003
  5. ncbi Determinants of serum total and free testosterone levels in women over the age of 65 years
    Anne R Cappola
    Division of Endocrinology, Diabetes, and Metabolism, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 6021, USA
    J Clin Endocrinol Metab 92:509-16. 2007
  6. pmc Relationship of low plasma klotho with poor grip strength in older community-dwelling adults: the InCHIANTI study
    Richard D Semba
    Department of Ophthalmology, The Johns Hopkins University School of Medicine, Smith Building, M015, 400 N Broadway, Baltimore, MD 21287, USA
    Eur J Appl Physiol 112:1215-20. 2012
  7. pmc Trajectories of dehydroepiandrosterone sulfate predict mortality in older adults: the cardiovascular health study
    Anne R Cappola
    SCM, Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, University of Pennsylvania School of Medicine, 764 CRB, 415 Curie Boulevard, Philadelphia, PA 19104, USA
    J Gerontol A Biol Sci Med Sci 64:1268-74. 2009
  8. pmc The natural history of subclinical hypothyroidism in the elderly: the cardiovascular health study
    Lily L Somwaru
    Division of Endocrinology, Diabetes, and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104 5160, USA
    J Clin Endocrinol Metab 97:1962-9. 2012
  9. pmc Relationship of low-circulating "anti-aging" klotho hormone with disability in activities of daily living among older community-dwelling adults
    Candace L Crasto
    Department of Ophthalmology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Rejuvenation Res 15:295-301. 2012
  10. pmc Relationship of serum fibroblast growth factor 23 with cardiovascular disease in older community-dwelling women
    Mansi Dalal
    Department of Ophthalmology, Johns Hopkins University School of Medicine, M015, Smith Building, 400 North Broadway, Baltimore, Maryland 21287, USA
    Eur J Endocrinol 165:797-803. 2011

Research Grants

Detail Information

Publications51

  1. ncbi Insulin-like growth factor I and interleukin-6 contribute synergistically to disability and mortality in older women
    Anne R Cappola
    Department of Medicine, University of Maryland, Baltimore, Maryland 21201, USA
    J Clin Endocrinol Metab 88:2019-25. 2003
    ..The joint effects of IGF-I and IL-6 may be important targets for treatments to prevent or minimize disability associated with aging...
  2. pmc DHEAS levels and mortality in disabled older women: the Women's Health and Aging Study I
    Anne R Cappola
    Division of Endocrinology, Diabetes, and Metabolism, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
    J Gerontol A Biol Sci Med Sci 61:957-62. 2006
    ..Low DHEAS levels are associated with mortality in older men, but the relationship between DHEAS levels and mortality in women is not clearly defined...
  3. pmc Thyroid status, cardiovascular risk, and mortality in older adults
    Anne R Cappola
    Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia 19104 6021, USA
    JAMA 295:1033-41. 2006
    ..Previous studies have suggested that subclinical abnormalities in thyroid-stimulating hormone levels are associated with detrimental effects on the cardiovascular system...
  4. ncbi Hypothyroidism and atherosclerosis
    Anne R Cappola
    Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, 19104, USA
    J Clin Endocrinol Metab 88:2438-44. 2003
  5. ncbi Determinants of serum total and free testosterone levels in women over the age of 65 years
    Anne R Cappola
    Division of Endocrinology, Diabetes, and Metabolism, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 6021, USA
    J Clin Endocrinol Metab 92:509-16. 2007
    ..Little is known about testosterone (T) levels and their determinants in women of late postmenopausal age...
  6. pmc Relationship of low plasma klotho with poor grip strength in older community-dwelling adults: the InCHIANTI study
    Richard D Semba
    Department of Ophthalmology, The Johns Hopkins University School of Medicine, Smith Building, M015, 400 N Broadway, Baltimore, MD 21287, USA
    Eur J Appl Physiol 112:1215-20. 2012
    ..20, standard error = 0.35, P = 0.0009) in adults with plasma klotho <681 pg/mL. These results suggest that older adults with lower plasma klotho have poor skeletal muscle strength...
  7. pmc Trajectories of dehydroepiandrosterone sulfate predict mortality in older adults: the cardiovascular health study
    Anne R Cappola
    SCM, Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, University of Pennsylvania School of Medicine, 764 CRB, 415 Curie Boulevard, Philadelphia, PA 19104, USA
    J Gerontol A Biol Sci Med Sci 64:1268-74. 2009
    ..Assessment of an individual's ability to maintain a DHEAS set point, through examination of multiple DHEAS levels over time, may provide insight into biologic aging...
  8. pmc The natural history of subclinical hypothyroidism in the elderly: the cardiovascular health study
    Lily L Somwaru
    Division of Endocrinology, Diabetes, and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104 5160, USA
    J Clin Endocrinol Metab 97:1962-9. 2012
    ..Studies of long-term outcomes of subclinical hypothyroidism have assessed only baseline thyroid function, despite natural transitions to euthyroidism and overt hypothyroidism over time...
  9. pmc Relationship of low-circulating "anti-aging" klotho hormone with disability in activities of daily living among older community-dwelling adults
    Candace L Crasto
    Department of Ophthalmology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Rejuvenation Res 15:295-301. 2012
    ..Low plasma klotho concentrations were independently associated with ADL disability among older community-dwelling men and women...
  10. pmc Relationship of serum fibroblast growth factor 23 with cardiovascular disease in older community-dwelling women
    Mansi Dalal
    Department of Ophthalmology, Johns Hopkins University School of Medicine, M015, Smith Building, 400 North Broadway, Baltimore, Maryland 21287, USA
    Eur J Endocrinol 165:797-803. 2011
    ..The aim of this study was to determine whether serum FGF23 is independently associated with cardiovascular disease in older community-dwelling women...
  11. pmc Plasma klotho and cardiovascular disease in adults
    Richard D Semba
    Department of Ophthalmology, School of Medicine, The Johns Hopkins University, Baltimore, Maryland, USA
    J Am Geriatr Soc 59:1596-601. 2011
    ..To determine whether plasma klotho, a recently discovered hormone that has been implicated in atherosclerosis, is related to prevalent cardiovascular disease (CVD) in adults...
  12. pmc Multiple hormonal deficiencies in anabolic hormones are found in frail older women: the Women's Health and Aging studies
    Anne R Cappola
    Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, University of Pennsylvania School of Medicine, 415 Curie Blvd, Philadelphia, PA 19104, USA
    J Gerontol A Biol Sci Med Sci 64:243-8. 2009
    ..We hypothesized that associations with frailty would most likely manifest in the presence of deficits in multiple anabolic hormones...
  13. pmc White blood cell counts, insulin-like growth factor-1 levels, and frailty in community-dwelling older women
    Sean X Leng
    Division of Geriatric Medicine and Gerontology, 5505 Hopkins Bayview Circle, Johns Hopkins School of Medicine, Baltimore, MD 21224, USA
    J Gerontol A Biol Sci Med Sci 64:499-502. 2009
    ..WBC subpopulations are known to produce IGF-1 and express IGF-1 receptors in vitro. However, in vivo relationships between WBC and IGF-1 and their joint contribution to frailty have not been investigated...
  14. pmc Higher serum free testosterone concentration in older women is associated with greater bone mineral density, lean body mass, and total fat mass: the cardiovascular health study
    Chevon M Rariy
    Division of Endocrinology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    J Clin Endocrinol Metab 96:989-96. 2011
    ..The physiological importance of endogenous testosterone (T) in older women is poorly understood...
  15. ncbi Subclinical hypothyroidism, weight change, and body composition in the elderly: the cardiovascular health study
    Margaret C Garin
    Division of Endocrinology, Diabetes, and Metabolism M C G, A R C, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania 19104 Department of Biostatistics A M A, University of Washington, Seattle, Washington 98155 Division of Endocrinology, Gerontology, and Metabolism J S L, Stanford University School of Medicine and Veterans Administration Palo Alto Health Care System, Palo Alto, California 94305 and Departments of Pathology and Biochemistry R P T, University of Vermont, Burlington, Vermont 05405
    J Clin Endocrinol Metab 99:1220-6. 2014
    ..003). Baseline weight and weight change did not differ by T3 levels. Conclusions: Our data do not support a clinically significant impact of subclinical hypothyroidism on weight status in the elderly. ..
  16. pmc Cardiovascular disease is associated with greater incident dehydroepiandrosterone sulfate decline in the oldest old: the cardiovascular health study all stars study
    Jason L Sanders
    Department of Medicine, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    J Am Geriatr Soc 58:421-6. 2010
    ..To describe cross-sectional and longitudinal associations with dehydroepiandrosterone sulfate (DHEAS) and change in DHEAS with age...
  17. pmc Low Serum Selenium Is Associated with Anemia Among Older Women Living in the Community: the Women's Health and Aging Studies I and II
    Richard D Semba
    The Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Biol Trace Elem Res 112:97-107. 2006
    ..47-0.84), adjusting for age, education, chronic diseases, iron status, and serum interleukin-6. We conclude that low serum selenium is independently associated with anemia among older women living in the community...
  18. pmc Plasma klotho and mortality risk in older community-dwelling adults
    Richard D Semba
    Baltimore, MD 21287, USA
    J Gerontol A Biol Sci Med Sci 66:794-800. 2011
    ..It is not known whether there is a relationship between plasma levels of secreted klotho protein and longevity in humans...
  19. pmc Association between interleukin-6 and lower extremity function after hip fracture--the role of muscle mass and strength
    Ram R Miller
    Division of Gerontology, Department of Epidemiology and Preventive Medicine, University of Maryland, Baltimore, Maryland 21201, USA
    J Am Geriatr Soc 56:1050-6. 2008
    ..To examine whether an effect on muscle mass or strength explains the association between interleukin-6 (IL-6) and lower extremity function in the year after hip fracture...
  20. pmc Longitudinal changes in thyroid function in the oldest old and survival: the cardiovascular health study all-stars study
    Avantika C Waring
    Division of Endocrinology, Diabetes, and Metabolism, Perelman School of Medicine at the University of Pennsylvania, 12 136 Translational Research Center, 3400 Civic Center Boulevard, Philadelphia, Pennsylvania 19104 5160, USA
    J Clin Endocrinol Metab 97:3944-50. 2012
    ..Data on thyroid function in the oldest old are sparse, and existing studies show conflicting evidence on the relationship between thyroid function and mortality in this age group...
  21. doi Hyperglycemia and incidence of frailty and lower extremity mobility limitations in older women
    Rita R Kalyani
    Divisions of Endocrinology, Johns Hopkins University, Baltimore, Maryland 21287, USA
    J Am Geriatr Soc 60:1701-7. 2012
    ..To determine the degree to which hyperglycemia predicts the development of frailty and lower extremity mobility limitations...
  22. pmc Serum fibroblast growth factor-23 and risk of incident chronic kidney disease in older community-dwelling women
    Richard D Semba
    Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    Clin J Am Soc Nephrol 7:85-91. 2012
    ..This study aimed to determine whether circulating FGF23 predicts incident CKD in community-dwelling women...
  23. pmc Higher serum testosterone concentration in older women is associated with insulin resistance, metabolic syndrome, and cardiovascular disease
    Shrita M Patel
    Division of Endocrinology, Diabetes, and Metabolism, University of Pennsylvania School of Medicine, 415 Curie Boulevard, Philadelphia, Pennsylvania 19104, USA
    J Clin Endocrinol Metab 94:4776-84. 2009
    ..Early postmenopausal women with higher testosterone (T) levels have increased insulin resistance (IR) and cardiovascular risk factors, but whether this translates into increased cardiovascular disease later in life is unknown...
  24. pmc Predictors of thyroid hormone initiation in older adults: results from the cardiovascular health study
    Lily L Somwaru
    Division of Endocrinology, Diabetes, and Metabolism, University of Pennsylvania School of Medicine, Philadelphia, USA
    J Gerontol A Biol Sci Med Sci 66:809-14. 2011
    ..Despite widespread use, there are no data on initiation of thyroid hormone use in older people. We report the prevalence of thyroid hormone use and predictors of thyroid hormone initiation in a population of older men and women...
  25. pmc Effects of metformin and leuprolide acetate on insulin resistance and testosterone levels in nondiabetic postmenopausal women: a randomized, placebo-controlled trial
    Shrita M Patel
    Division of Endocrinology, Diabetes, and Metabolism, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Fertil Steril 94:2161-6. 2010
    ..To determine whether insulin sensitizers lower androgen levels and whether androgen suppression improves insulin resistance in nondiabetic postmenopausal women...
  26. pmc Thyroid autoantibodies are associated with a reduced prevalence of frailty in community-dwelling older women
    George C Wang
    Division of Geriatric Medicine and Gerontology, Johns Hopkins University School of Medicine, 5505 Hopkins Bayview Circle, Baltimore, Maryland 21224, USA
    J Clin Endocrinol Metab 95:1161-8. 2010
    ..These trends were not observed with antinuclear antibodies. Conclusion: Independent of thyroid function status, community-dwelling older women who are seropositive for TgAbs and TPOAbs are less likely to be frail than seronegative women...
  27. ncbi Association of serum vitamin D levels with inflammatory response following hip fracture: the Baltimore Hip Studies
    Ram R Miller
    Division of Gerontology, Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    J Gerontol A Biol Sci Med Sci 62:1402-6. 2007
    ..Vitamin D, known for its role in calcium homeostasis, may also regulate immune function. Whether vitamin D deficiency at the time of hip fracture is associated with the inflammatory response postfracture is not known...
  28. pmc Frailty status and altered glucose-insulin dynamics
    Rita Rastogi Kalyani
    Division of Endocrinology and Metabolism, Department of Medicine, Johns Hopkins University School of Medicine, 1830 East Monument Street, Suite 333, Baltimore, MD 21287, USA
    J Gerontol A Biol Sci Med Sci 67:1300-6. 2012
    ..We examined women in their 80s and 90s and evaluated the hypothesis that abnormalities in the dynamic response of glucose and insulin to a glucose load are associated with frailty status...
  29. pmc Serum 25-hydroxyvitamin D and pulmonary function in older disabled community-dwelling women
    Richard D Semba
    Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    J Gerontol A Biol Sci Med Sci 67:683-9. 2012
    ..Our objective was to examine the relationship between serum 25-hydroxyvitamin D (25[OH]D), serum parathyroid hormone, and pulmonary function in older women...
  30. pmc Low serum 25-hydroxyvitamin D concentrations are associated with greater all-cause mortality in older community-dwelling women
    Richard D Semba
    Department of Ophthalmology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, MD 21287, USA
    Nutr Res 29:525-30. 2009
    ..4 nmol/L) of 25(OH)D in a multivariate Cox proportional hazards model adjusting for demographics, season, and conventional risk factors. Older community-dwelling women with low 25(OH)D levels are at an increased risk of death...
  31. pmc Persistent subclinical hypothyroidism and cardiovascular risk in the elderly: the cardiovascular health study
    Kristen A Hyland
    Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, 12 136 Translational Research Center, 3400 Civic Center Boulevard, Philadelphia, Pennsylvania 19104 5160, USA
    J Clin Endocrinol Metab 98:533-40. 2013
    ..Objective: We assessed the risks of coronary heart disease (CHD), heart failure (HF), and cardiovascular (CV) death in older adults with persistent subclinical hypothyroidism...
  32. pmc Resting metabolic rate in old-old women with and without frailty: variability and estimation of energy requirements
    Carlos O Weiss
    Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland 21224, USA
    J Am Geriatr Soc 60:1695-700. 2012
    ..To measure resting metabolic rate (RMR) in old-old adults living in the community and examine the association between measured RMR and frailty status and compare it with expected RMR generated by a predictive equation...
  33. ncbi Low serum selenium and total carotenoids predict mortality among older women living in the community: the women's health and aging studies
    Amanda L Ray
    The Johns Hopkins Medical Institutions, Baltimore, MD, USA
    J Nutr 136:172-6. 2006
    ..77, 95% CI 0.64-0.84/1 SD increase in log(e) total carotenoids; P = 0.009) were associated with a lower risk of mortality. Women living in the community who have higher serum selenium and carotenoids are at a lower risk of death...
  34. pmc High frequency of and factors associated with thyroid hormone over-replacement and under-replacement in men and women aged 65 and over
    Lily L Somwaru
    Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    J Clin Endocrinol Metab 94:1342-5. 2009
    ..Thyroid hormone use is common in older populations, but the frequency of over- or under-replacement is debated...
  35. ncbi Serum levels of insulin-like growth factor-I (IGF-I) and dehydroepiandrosterone sulfate (DHEA-S), and their relationships with serum interleukin-6, in the geriatric syndrome of frailty
    Sean X Leng
    Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Aging Clin Exp Res 16:153-7. 2004
    ..In the present study, our aim is to evaluate the possible role of endocrine dysregulation and its relationship with serum IL-6 in the pathogenesis of this syndrome...
  36. ncbi Physical performance and frailty in chronic kidney disease
    PETER P REESE
    Renal Division, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, University of Pennsylvania, Philadelphia, PA, USA
    Am J Nephrol 38:307-15. 2013
    ..Chronic kidney disease (CKD) is also strongly associated with these outcomes. The risks of poor physical performance and frailty among CKD patients, however, are not well established...
  37. ncbi Higher levels and blunted diurnal variation of cortisol in frail older women
    Ravi Varadhan
    Division of Geriatric Medicine and Gerontology, School of Medicine, John Hopkins University, Baltimore, MD, USA
    J Gerontol A Biol Sci Med Sci 63:190-5. 2008
    ..We evaluated whether higher levels and blunted diurnal variation of salivary cortisol are cross-sectionally associated with frailty burden...
  38. ncbi Dehydroepiandrosterone sulfate and postmenopausal women
    Rachna M Goel
    Division of Endocrinology, Diabetes, and Metabolism, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Curr Opin Endocrinol Diabetes Obes 18:171-6. 2011
    ..The goal of this article is to critically review published studies to determine if there is a role for DHEA supplementation in postmenopausal women...
  39. pmc Clinical review: The human experience with ghrelin administration
    Margaret C Garin
    Division of Endocrinology, Diabetes, and Metabolism, Perelman School of Medicine at the University of Pennsylvania, 3400 Civic Center Boulevard, Philadelphia, Pennsylvania 19104 5160, USA
    J Clin Endocrinol Metab 98:1826-37. 2013
    ..Clinical trials have been performed in a variety of patient populations, but there is no comprehensive review of the beneficial and adverse consequences of ghrelin administration to humans...
  40. pmc Integrated management of type 2 diabetes mellitus and depression treatment to improve medication adherence: a randomized controlled trial
    Hillary R Bogner
    Department of Family Medicine and Community Health, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Ann Fam Med 10:15-22. 2012
    ....
  41. pmc Sex hormones are associated with right ventricular structure and function: The MESA-right ventricle study
    Corey E Ventetuolo
    Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York, USA
    Am J Respir Crit Care Med 183:659-67. 2011
    ..Sex hormones have effects on the left ventricle, but hormonal influences on the right ventricle (RV) are unknown...
  42. ncbi The intersection of cancer and aging: establishing the need for breast cancer rehabilitation
    Kathryn H Schmitz
    Division of Clinical Epidemiology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, 921 Blockley Hall, 423 Guardian Drive, Philadelphia, PA 19104, USA
    Cancer Epidemiol Biomarkers Prev 16:866-72. 2007
    ....
  43. ncbi Persistent changes in interleukin-6 and lower extremity function following hip fracture
    Ram R Miller
    University of Maryland, School of Medicine, Division of Gerontology, Department of Epidemiology and Preventive Medicine, 660 W Redwood St, Suite 200, Baltimore, MD 21201, USA
    J Gerontol A Biol Sci Med Sci 61:1053-8. 2006
    ..Although an inflammatory reaction would be expected following a hip fracture, whether the degree of this response is associated with adverse functional outcomes is unknown...
  44. doi Factors impacting the departure rates of female and male junior medical school faculty: evidence from a longitudinal analysis
    Rebecca M Speck
    Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA
    J Womens Health (Larchmt) 21:1059-65. 2012
    ..Our objective was to investigate the association of individual level risk factors, track of academic appointment, and use of institutional leave policies with departure in junior faculty of a research-intensive school of medicine...
  45. ncbi Insulin sensitizing pharmacotherapy for prevention of myocardial infarction in patients with diabetes mellitus
    William H Sauer
    Cardiovascular Division, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
    Am J Cardiol 97:651-4. 2006
    ....
  46. pmc Subclinical thyroid dysfunction, cardiac function, and the risk of heart failure. The Cardiovascular Health study
    Nicolas Rodondi
    Department of Ambulatory Care and Community Medicine, University of Lausanne, Lausanne, Switzerland
    J Am Coll Cardiol 52:1152-9. 2008
    ..The goal of this study was to determine whether subclinical thyroid dysfunction was associated with incident heart failure (HF) and echocardiogram abnormalities...
  47. ncbi Association of total insulin-like growth factor-I, insulin-like growth factor binding protein-1 (IGFBP-1), and IGFBP-3 levels with incident coronary events and ischemic stroke
    Robert C Kaplan
    Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York 10461, USA, and Department of Medicine, Lady Davis Research Institute of Jewish General Hospital, Montreal, Quebec, Canada
    J Clin Endocrinol Metab 92:1319-25. 2007
    ..Prior observational studies have demonstrated that the GH/IGF axis is associated with cardiovascular disease. However, this association has not been extensively studied among older adults...
  48. pmc Insulin-like growth factor-(IGF)-axis, inflammation, and glucose intolerance among older adults
    Swapnil N Rajpathak
    Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY 11375, USA
    Growth Horm IGF Res 18:166-73. 2008
    ..We did not confirm prior associations of low IGF-I with glucose intolerance in this cohort of older individuals...
  49. ncbi Is research on hormones and aging finished? No! Just started!
    Anne R Cappola
    J Gerontol A Biol Sci Med Sci 63:696-7. 2008
  50. pmc High insulinlike growth factor binding protein 1 level predicts incident congestive heart failure in the elderly
    Robert C Kaplan
    Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Am Heart J 155:1006-12. 2008
    ..We investigated the association between fasting plasma levels of IGF-I, IGFBP-1, IGFBP-3, and insulin and risk of incident CHF in the prospective Cardiovascular Health Study...
  51. ncbi Subclinical thyroid dysfunction and the heart
    Anne R Cappola
    J Clin Endocrinol Metab 92:3404-5. 2007

Research Grants1

  1. Androgens, Myostatin, and Sarcopenia in Older Women
    Anne Cappola; Fiscal Year: 2006
    ..abstract_text> ..