Lisa A Cannon-Albright

Summary

Affiliation: University of Utah
Country: USA

Publications

  1. pmc Analysis of Xq27-28 linkage in the international consortium for prostate cancer genetics (ICPCG) families
    Joan E Bailey-Wilson
    Inherited Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Baltimore, MD 21224, USA
    BMC Med Genet 13:46. 2012
  2. ncbi request reprint Creation of a national resource with linked genealogy and phenotypic data: the Veterans Genealogy Project
    Lisa A Cannon-Albright
    Division of Genetic Epidemiology, Department of Medicine, University of Utah School of Medicine, Salt Lake City, UT, USA
    Genet Med 15:541-7. 2013
  3. pmc Linkage analysis of extended high-risk pedigrees replicates a cutaneous malignant melanoma predisposition locus on chromosome 9q21
    Lisa A Cannon-Albright
    Department of Medicine, University of Utah School of Medicine, Salt Lake City, Utah, USA
    J Invest Dermatol 133:128-34. 2013
  4. pmc No evidence of BRCA2 mutations in chromosome 13q-linked Utah high-risk prostate cancer pedigrees
    Kristina Allen Brady
    Genetic Epidemiology Group, Department of Biomedical Informatics, University of Utah School of Medicine, 391 Chipeta Way, Suite D, Salt Lake City, UT 84108 USA
    BMC Res Notes 2:94. 2009
  5. pmc Extracting disease risk profiles from expression data for linkage analysis: application to prostate cancer
    G Bryce Christensen
    Department of Biomedical Informatics, University of Utah, 391 Chipeta Way Suite D, Salt Lake City, Utah 84108 1266, USA
    BMC Proc 1:S82. 2007
  6. pmc Evidence for a heritable predisposition to Chronic Fatigue Syndrome
    Frederick Albright
    Pharmacotherapy Outcomes Research Center, Department of Pharmacotherapy, College of Pharmacy, University of Utah, USA
    BMC Neurol 11:62. 2011
  7. ncbi request reprint Utah family-based analysis: past, present and future
    Lisa A Cannon Albright
    Division of Genetic Epidemiology, Department of Biomedical Informatics, University of Utah School of Medicine, Salt Lake City, Utah 84108, USA
    Hum Hered 65:209-20. 2008
  8. pmc High quality and quantity Genome-wide germline genotypes from FFPE normal tissue
    Lisa A Cannon-Albright
    Genetic Epidemiology, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, UT, USA
    BMC Res Notes 4:159. 2011
  9. pmc Genome-wide linkage analysis of 1,233 prostate cancer pedigrees from the International Consortium for Prostate Cancer Genetics using novel sumLINK and sumLOD analyses
    G Bryce Christensen
    University of Utah ICPCG Group and Division of Genetic Epidemiology, University of Utah School of Medicine, Salt Lake City, Utah 84108, USA
    Prostate 70:735-44. 2010
  10. ncbi request reprint Confirmation of chromosome 7q11 locus for predisposition to intracranial aneurysm
    James M Farnham
    Department of Medical Informatics, University of Utah School of Medicine, 391 Chipeta Way, Salt Lake City, UT 84108, USA
    Hum Genet 114:250-5. 2004

Research Grants

Detail Information

Publications58

  1. pmc Analysis of Xq27-28 linkage in the international consortium for prostate cancer genetics (ICPCG) families
    Joan E Bailey-Wilson
    Inherited Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Baltimore, MD 21224, USA
    BMC Med Genet 13:46. 2012
    ..Current evidence suggests that genetic linkage to prostate cancer has been found on several chromosomes including the X; however, identification of causative genes has been elusive...
  2. ncbi request reprint Creation of a national resource with linked genealogy and phenotypic data: the Veterans Genealogy Project
    Lisa A Cannon-Albright
    Division of Genetic Epidemiology, Department of Medicine, University of Utah School of Medicine, Salt Lake City, UT, USA
    Genet Med 15:541-7. 2013
    ..When complete, this US genealogy will be record linked to the National Veteran's Health Administration medical data representing more than 8 million US veterans...
  3. pmc Linkage analysis of extended high-risk pedigrees replicates a cutaneous malignant melanoma predisposition locus on chromosome 9q21
    Lisa A Cannon-Albright
    Department of Medicine, University of Utah School of Medicine, Salt Lake City, Utah, USA
    J Invest Dermatol 133:128-34. 2013
    ..This report confirms that linkage analysis for common disorders can be successful in analysis of high-density markers in sets of singly informative high-risk pedigrees...
  4. pmc No evidence of BRCA2 mutations in chromosome 13q-linked Utah high-risk prostate cancer pedigrees
    Kristina Allen Brady
    Genetic Epidemiology Group, Department of Biomedical Informatics, University of Utah School of Medicine, 391 Chipeta Way, Suite D, Salt Lake City, UT 84108 USA
    BMC Res Notes 2:94. 2009
    ..CONCLUSION: In this set of high-risk prostate cancer pedigrees with at least nominal linkage evidence to BRCA2, we saw no evidence for segregating BRCA2 protein truncating mutations in heritable prostate cancer...
  5. pmc Extracting disease risk profiles from expression data for linkage analysis: application to prostate cancer
    G Bryce Christensen
    Department of Biomedical Informatics, University of Utah, 391 Chipeta Way Suite D, Salt Lake City, Utah 84108 1266, USA
    BMC Proc 1:S82. 2007
    ..Our results do indicate there exists potential to augment our current knowledge about the relationships among genes associated with complex diseases using expression data...
  6. pmc Evidence for a heritable predisposition to Chronic Fatigue Syndrome
    Frederick Albright
    Pharmacotherapy Outcomes Research Center, Department of Pharmacotherapy, College of Pharmacy, University of Utah, USA
    BMC Neurol 11:62. 2011
    ....
  7. ncbi request reprint Utah family-based analysis: past, present and future
    Lisa A Cannon Albright
    Division of Genetic Epidemiology, Department of Biomedical Informatics, University of Utah School of Medicine, Salt Lake City, Utah 84108, USA
    Hum Hered 65:209-20. 2008
    ..Example analyses and high-risk pedigrees are presented. Finally we briefly review ways this resource, or others like it, may expand in future...
  8. pmc High quality and quantity Genome-wide germline genotypes from FFPE normal tissue
    Lisa A Cannon-Albright
    Genetic Epidemiology, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, UT, USA
    BMC Res Notes 4:159. 2011
    ..abstract:..
  9. pmc Genome-wide linkage analysis of 1,233 prostate cancer pedigrees from the International Consortium for Prostate Cancer Genetics using novel sumLINK and sumLOD analyses
    G Bryce Christensen
    University of Utah ICPCG Group and Division of Genetic Epidemiology, University of Utah School of Medicine, Salt Lake City, Utah 84108, USA
    Prostate 70:735-44. 2010
    ..The recently developed sumLINK and sumLOD statistics are powerful tools for linkage analysis in the presence of heterogeneity...
  10. ncbi request reprint Confirmation of chromosome 7q11 locus for predisposition to intracranial aneurysm
    James M Farnham
    Department of Medical Informatics, University of Utah School of Medicine, 391 Chipeta Way, Salt Lake City, UT 84108, USA
    Hum Genet 114:250-5. 2004
    ..34, at D7S2421, corrected P=0.001). This study is the first to confirm the linkage of the 7q11 locus for IA...
  11. ncbi request reprint Longitudinal assessment of the nevus phenotype in a melanoma kindred
    Scott R Florell
    The Melanoma Program, Huntsman Cancer Institute, University of Utah, 2000 Circle of Hope, Salt Lake City, UT 84112 5550, USA
    J Invest Dermatol 123:576-82. 2004
    ..Continued accumulation of nevi in mutation carriers supports a nevogenic role for this CDKN2A mutation. An intermediate nevus phenotype in non-carrier family members suggests the presence of additional modifier genes...
  12. ncbi request reprint Evidence for a heritable component in death resulting from aortic and mitral valve diseases
    Benjamin D Horne
    Genetic Epidemiology Division, Department of Medical Informatics, University of Utah, 391 Chipeta Way, Suite D, Salt Lake City, UT 84108 1266, USA
    Circulation 110:3143-8. 2004
    ..This study evaluated the familiality of death resulting from aortic, mitral, and all valvular diseases using a population-based genealogy linked to death records...
  13. doi request reprint Utah Population Database: a tool to study the hereditary element of nonsyndromic neurosurgical diseases
    Toba N Niazi
    Department of Neurosurgery, University of Utah School of Medicine, Salt Lake City, Utah 84132, USA
    Neurosurg Focus 28:E1. 2010
    ..From this information, one can identify possible genetic targets for future therapies...
  14. ncbi request reprint Statistical recombinant mapping in extended high-risk Utah pedigrees narrows the 8q24 prostate cancer locus to 2.0 Mb
    Nicola J Camp
    Division of Genetic Epidemiology, Department of Biomedical Informatics, University of Utah School of Medicine, Salt Lake City, Utah 84108, USA
    Prostate 67:1456-64. 2007
    ..In addition to potential allelic heterogeneity, 8q24 exhibits strong linkage disequilibrium over vast distances and is prone to chromosomal aberrations...
  15. ncbi request reprint Identification of specific Y chromosomes associated with increased prostate cancer risk
    Lisa A Cannon-Albright
    Division of Genetic Epidemiology, Department of Medicine, University of Utah School of Medicine, Salt Lake City, Utah George E Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, Utah Huntsman Cancer Institute, Salt Lake City, Utah
    Prostate 74:991-8. 2014
    ..Evidence supports the possibility of a role of the Y chromosome in prostate cancer, but controversy exists...
  16. pmc Replication of the 10q11 and Xp11 prostate cancer risk variants: results from a Utah pedigree-based study
    Nicola J Camp
    Department of Biomedical Informatics, University of Utah School of Medicine, Salt Lake City, UT 84108, USA
    Cancer Epidemiol Biomarkers Prev 18:1290-4. 2009
    ..We also nominally replicated the association of prostate cancer with rs5945619 (Xp11). In particular, it seems that the susceptibility locus at 10q11 maybe involved in familial, early-onset disease...
  17. ncbi request reprint A role for XRCC4 in age at diagnosis and breast cancer risk
    Kristina Allen-Brady
    Genetic Epidemiology, Department of Medical Informatics, University of Utah, Salt Lake City, 84108, USA
    Cancer Epidemiol Biomarkers Prev 15:1306-10. 2006
    ..Our results suggest that XRCC4 may play a role in the age at diagnosis and risk of breast cancer in non-BRCA1/2, heritable breast cancer cases...
  18. ncbi request reprint Characterization of linkage disequilibrium structure, mutation history, and tagging SNPs, and their use in association analyses: ELAC2 and familial early-onset prostate cancer
    Nicola J Camp
    Genetic Epidemiology Division, Department of Medical Informatics, University of Utah School of Medicine, Salt Lake City, Utah, USA
    Genet Epidemiol 28:232-43. 2005
    ....
  19. pmc Pairwise shared genomic segment analysis in three Utah high-risk breast cancer pedigrees
    Zheng Cai
    Department of Biomedical Informatics, University of Utah Medical School, Health Sciences Education Building, Salt Lake City, UT 84112, USA
    BMC Genomics 13:676. 2012
    ..We applied a new weighted pairwise shared genomic segment (pSGS) analysis for susceptibility gene localization to high-density genomewide SNP data in three extended high-risk breast cancer pedigrees...
  20. ncbi request reprint Examination of ELN as a candidate gene in the Utah intracranial aneurysm pedigrees
    Nicole Berthelemy-Okazaki
    Department of Medical Informatics, Ogden, Utah, USA
    Stroke 36:1283-4. 2005
    ..Subsequent linkage analysis of the ELN region on chromosome 7q11 in high-risk Utah IA pedigrees significantly confirmed linkage between IA and the ELN region...
  21. doi request reprint A comprehensive survey of cancer risks in extended families
    Craig C Teerlink
    Division of Genetic Epidemiology, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, Utah, USA
    Genet Med 14:107-14. 2012
    ..This population-based description of cancer clustering describes patterns of cancer coaggregation suggestive of a genetic predisposition...
  22. pmc Population-based family history-specific risks for colorectal cancer: a constellation approach
    David P Taylor
    Department of Biomedical Informatics, University of Utah, Salt Lake City, Utah
    Gastroenterology 138:877-85. 2010
    ..We report familial relative risk (FRR) in probands with various combinations, or constellations, of affected relatives, extending to third-degree...
  23. ncbi request reprint Genome-wide linkage analyses of extended Utah pedigrees identifies loci that influence recurrent, early-onset major depression and anxiety disorders
    Nicola J Camp
    Genetic Research, Intermountain Health Care, Salt Lake City, Utah 84108, USA
    Am J Med Genet B Neuropsychiatr Genet 135:85-93. 2005
    ..Further, it supports the hypothesis that MDD and anxiety disorders have over-lapping genetic etiologies and suggests that comorbid diagnoses may be useful in defining more genetically homogeneous forms of MDD for linkage mapping...
  24. pmc Empiric evidence for a genetic contribution to predisposition to surgical site infection
    James P Lee
    Department of Anesthesiology, University of Utah School of Medicine, Salt Lake City, UT 84132, USA
    Wound Repair Regen 21:211-5. 2013
    ..019). The RR for third-degree relatives of cases was significantly elevated (1.62, p = 0.029). The significant excess relatedness and the significantly elevated RR to distant relatives support a genetic predisposition to acquiring SSI...
  25. pmc Evidence of an inherited predisposition for cervical spondylotic myelopathy
    Alpesh A Patel
    Department of Orthopaedics, University of Utah School of Medicine, Salt Lake City, UT, USA
    Spine (Phila Pa 1976) 37:26-9. 2012
    ..A retrospective, population-based study cross-referencing a genealogic database of over 2 million Utah residents with 10 years of clinical diagnosis data from a large tertiary hospital...
  26. ncbi request reprint A genealogical assessment of heritable predisposition to asthma mortality
    Craig C Teerlink
    Department of Biomedical Informatics, University of Utah, Salt Lake City, Utah 84112 5750, USA
    Am J Respir Crit Care Med 176:865-70. 2007
    ..Asthma is a multifactorial disease; genetic factors have been suggested but have not been well defined...
  27. doi request reprint How well does family history predict who will get colorectal cancer? Implications for cancer screening and counseling
    David P Taylor
    Department of Biomedical Informatics, University of Utah School of Medicine, Salt Lake City, Utah 84112 5750, USA
    Genet Med 13:385-91. 2011
    ..Using a large, retrospective cohort from the Utah Population Database, we assess how well family history predicts who will acquire colorectal cancer during a 20-year period...
  28. ncbi request reprint Population-based assessment of non-melanoma cancer risk in relatives of cutaneous melanoma probands
    April A Larson
    Department of Dermatology, University of Utah School of Medicine, Salt Lake City, Utah 84108, USA
    J Invest Dermatol 127:183-8. 2007
    ..The increased risks for five additional cancer types in first-degree relatives of melanoma cases suggest that individuals with a family history of melanoma should strictly adhere to recommended screenings for all cancers...
  29. pmc Association analysis of 9,560 prostate cancer cases from the International Consortium of Prostate Cancer Genetics confirms the role of reported prostate cancer associated SNPs for familial disease
    Craig C Teerlink
    Division of Genetic Epidemiology, Department of Medicine, University of Utah School of Medicine, Salt Lake City, UT, USA
    Hum Genet 133:347-56. 2014
    ..The results indicate that the majority of common, low-risk alleles identified in GWAS studies for all prostate cancer also contribute risk for familial prostate cancer, and that some may contribute risk to aggressive disease. ..
  30. ncbi request reprint Multiple primary melanomas in a CDKN2A mutation carrier exposed to ionizing radiation
    Mark J Eliason
    Department of Dermatology, Health Sciences Center, University of Utah, Salt Lake City, UT 84112 5550, USA
    Arch Dermatol 143:1409-12. 2007
    ..We describe a patient from a familial melanoma pedigree with 7 primary melanomas on the right side of her body, the first occurring 5 years after exposure to atmospheric nuclear bomb testing in the 1950s...
  31. ncbi request reprint The familiality of pelvic organ prolapse in the Utah Population Database
    Peggy A Norton
    Department of Obstetrics and Gynecology, Division of Urogynecology and Reconstructive Pelvic Surgery, University of Utah Health Sciences Center, Salt Lake City, UT 84132, USA
    Int Urogynecol J 24:413-8. 2013
    ..Pelvic organ prolapse (POP) in women is a common condition whose etiology is poorly understood. There is increasing evidence that POP is heritable. The aim of our study was to define and evaluate familial clustering of POP...
  32. doi request reprint Comparison of compliance for colorectal cancer screening and surveillance by colonoscopy based on risk
    David P Taylor
    Department of Biomedical Informatics, University of Utah, School of Medicine, Salt Lake City, Utah 84112 5750, USA
    Genet Med 13:737-43. 2011
    ..To compare colonoscopy screening/surveillance rates by level of risk for colorectal cancer based on age, personal history of adenomatous polyps or colorectal cancer, or family history of colorectal cancer...
  33. ncbi request reprint Lobular breast cancer: excess familiality observed in the Utah Population Database
    Kristina Allen-Brady
    Genetic Epidemiology, Department of Medical Informatics, University of Utah School of Medicine, Salt Lake City, 84108, USA
    Int J Cancer 117:655-61. 2005
    ..Relatives of women with LOB are at higher risk for BC than relatives of other BC subtypes; a more rigorous BC screening regime may be warranted for these individuals...
  34. ncbi request reprint Localization of a prostate cancer predisposition gene to an 880-kb region on chromosome 22q12.3 in Utah high-risk pedigrees
    Nicola J Camp
    Division of Genetic Epidemiology, Department of Biomedical Informatics, University of Utah School of Medicine, Salt Lake City, Utah 84108, USA
    Cancer Res 66:10205-12. 2006
    ..We are mutation screening candidate genes in this region to identify specific genetic variants segregating in these pedigrees...
  35. doi request reprint Familial clustering of endometrial cancer in a well-defined population
    Hillary M Moore Seger
    Department of Obstetrics and Gynecology, University of Utah, Salt Lake City, UT, USA
    Gynecol Oncol 122:75-8. 2011
    ..Using a genealogical database, we examined risk of endometrial cancer among family members of individuals with endometrial cancer...
  36. pmc Evidence for an inherited predisposition contributing to the risk for rotator cuff disease
    Robert Z Tashjian
    University of Utah Orthopaedic Center, Salt Lake City, UT 84108, USA
    J Bone Joint Surg Am 91:1136-42. 2009
    ..We used a population-based resource combining genealogical data for Utah with clinical diagnosis data from a large Utah hospital to test the hypothesis of excess familial clustering for rotator cuff disease...
  37. ncbi request reprint Population-based prevalence of CDKN2A mutations in Utah melanoma families
    Mark J Eliason
    Department of Dermatology, University of Utah Health Sciences Center, Salt Lake City, Utah, USA
    J Invest Dermatol 126:660-6. 2006
    ..We observed a significantly elevated rate of pancreatic cancer in one of four families with a deleterious CDKN2A mutation...
  38. pmc Significant evidence for a heritable contribution to cancer predisposition: a review of cancer familiality by site
    Frederick Albright
    Department of Pharmacotherapy, University of Utah College of Pharmacy, Salt Lake City, USA
    BMC Cancer 12:138. 2012
    ..The Utah Population Database (UPDB) has provided important illumination of the familial contribution to cancer risk by cancer site...
  39. pmc Significant linkage evidence for a predisposition gene for pelvic floor disorders on chromosome 9q21
    Kristina Allen-Brady
    Department of Biomedical Informatics, University of Utah School of Medicine, Salt Lake City, UT 84105, USA
    Am J Hum Genet 84:678-82. 2009
    ..41 under a recessive model. Seventeen pedigrees (53%) had at least nominal evidence for linkage on a by-pedigree basis at this region. These results provide evidence for a predisposition gene for PFDs on chromosome 9q...
  40. ncbi request reprint High-resolution characterization of linkage disequilibrium structure and selection of tagging single nucleotide polymorphisms: application to the cholesteryl ester transfer protein gene
    Benjamin D Horne
    Cardiovascular Department, LDS Hospital, Salt Lake City, UT 84143, USA
    Ann Hum Genet 70:524-34. 2006
    ..This study provides an optimal set of tSNPs for association analyses of CETP. The observed complexity of LD structure highlights the importance of using methods, such as PCA, that allow for multiple dynamics in intragenic LD structure...
  41. ncbi request reprint Identification of excess clustering of coronary heart diseases among extended pedigrees in a genealogical population database
    Benjamin D Horne
    Genetic Epidemiology Division, Department of Medical Informatics, University of Utah, Salt Lake City, UT 84108 1266, USA
    Am Heart J 152:305-11. 2006
    ..This study evaluated deaths caused by CAD, MI, hypertensive heart disease (HtnHD), and congestive heart failure (CHF) among close and distant relatives...
  42. pmc Significant evidence for linkage to chromosome 5q13 in a genome-wide scan for asthma in an extended pedigree resource
    Craig C Teerlink
    Department of Biomedical Informatics, Division of Genetic Epidemiology, University of Utah School of Medicine, Salt Lake City, UT 84112 5750, USA
    Eur J Hum Genet 17:636-43. 2009
    ..The evidence of linkage at the 5q13 region represents the first significant evidence for linkage on a genome-wide basis for this locus. Linked pedigrees localize the region to approximately between 92.3-105.5 Mb...
  43. pmc Compelling evidence for a prostate cancer gene at 22q12.3 by the International Consortium for Prostate Cancer Genetics
    Nicola J Camp
    University of Utah ICPCG Group and Division of Genetic Epidemiology, University of Utah School of Medicine, 391 Chipeta Way, Suite D, Salt Lake City, UT 84108, USA
    Hum Mol Genet 16:1271-8. 2007
    ..This collaborative study by the ICPCG illustrates the value of consortium efforts and the continued utility of linkage analysis using informative pedigrees to localize genes for complex diseases...
  44. doi request reprint A population-based description of familial clustering of pancreatic cancer
    Brian H Shirts
    Department of Pathology, University of Utah, Salt Lake City, Utah, USA
    Clin Gastroenterol Hepatol 8:812-6. 2010
    ..Several familial pancreatic cancer syndromes have been identified. However, the prevalence of familial pancreatic cancers in the general population has not been well defined...
  45. ncbi request reprint Genomic search for prostate cancer predisposition loci in Utah pedigrees
    Nicola J Camp
    Genetic Epidemiology, Department of Medical Informatics, University of Utah, Salt Lake City, Utah 84108, USA
    Prostate 65:365-74. 2005
    ..We report a genome linkage scan in extended Utah pedigrees, utilizing a pedigree-splitting approach to reduce intra-familial heterogeneity...
  46. ncbi request reprint Population-based analysis of prognostic factors and survival in familial melanoma
    Scott R Florell
    Department of Dermatology, Melanoma Program, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA
    J Clin Oncol 23:7168-77. 2005
    ..We sought to determine whether melanomas that occur in a familial setting demonstrate different prognostic and survival statistics relative to sporadic melanoma...
  47. pmc A familial component to human rectal cancer, independent of colon cancer risk
    John Scott Maul
    Department of Medical Oncology, University of Utah School of Medicine, Salt Lake City, Utah, USA
    Clin Gastroenterol Hepatol 5:1080-4. 2007
    ..The Utah Population Database (UPDB) is unique; it links genealogy for over 2 million Utah individuals to a statewide Cancer Registry. We have investigated the familial nature of rectal cancer, considered independently from colon cancer...
  48. pmc Complex genotype sarcomas display familial inheritance independent of known cancer predisposition syndromes
    Kevin B Jones
    Sarcoma Services, Department of Orthopaedics, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, USA
    Cancer Epidemiol Biomarkers Prev 20:751-7. 2011
    ..The low incidence of sarcomas in the general population makes heritable contribution to disease risk difficult to discern beyond highly penetrant Mendelian syndromes...
  49. ncbi request reprint Dissecting the genetic etiology of major depressive disorder using linkage analysis
    Nicola J Camp
    Division of Genetic Epidemiology, Department of Medical Informatics, University of Utah School of Medicine, Salt Lake City, UT 84108, USA
    Trends Mol Med 11:138-44. 2005
    ..Genes found might influence specific subtypes of MDD or broader phenotypes, leading to enhanced clinical characterization and management of MDD...
  50. pmc A parallel genetic algorithm to discover patterns in genetic markers that indicate predisposition to multifactorial disease
    Tobias Rausch
    Department of Biomedical Informatics, University of Utah School of Medicine, Salt Lake City, UT 84112, USA
    Comput Biol Med 38:826-36. 2008
    ..In particular, the correlation analysis of IBD expression patterns might hint to possible gene-gene interactions and the filtering might be a fruitful approach to distinguish true correlation signals from noise...
  51. pmc Fine-mapping CASP8 risk variants in breast cancer
    Nicola J Camp
    Division of Genetic Epidemiology, University of Utah School of Medicine, Salt Lake City, Utah, USA
    Cancer Epidemiol Biomarkers Prev 21:176-81. 2012
    ..To define a risk haplotype and map the CASP8 gene region with respect to underlying susceptibility variant/s, we screened four genes in the CASP8 region on 2q33-q34 for breast cancer risk...
  52. pmc Evidence for an inherited predisposition to lumbar disc disease
    Alpesh A Patel
    Department of Orthopaedics, University of Utah School of Medicine, Salt Lake City, UT 84108, USA
    J Bone Joint Surg Am 93:225-9. 2011
    ..The purpose of the present study was to define population-based familial clustering among individuals with a diagnosis of, or treated for, lumbar disc herniation or disc degeneration...
  53. ncbi request reprint Extracolonic cancers associated with hereditary nonpolyposis colorectal cancer in the Utah Population Database
    John Scott Maul
    Department of Cancer Outreach and Prevention, Huntsman Cancer Institute, Salt Lake City, Utah, USA
    Am J Gastroenterol 101:1591-6. 2006
    ..The data describing the extracolonic cancers associated with hereditary nonpolyposis colorectal cancer (HNPCC) are variable...
  54. doi request reprint Evidence for a heritable predisposition to death due to influenza
    Frederick S Albright
    Department of Pharmacotherapy, University of Utah College of Pharmacy, Salt Lake City, USA
    J Infect Dis 197:18-24. 2008
    ..These data provide strong support for a heritable contribution to predisposition to death due to influenza...
  55. pmc Meta association of colorectal cancer confirms risk alleles at 8q24 and 18q21
    Karen Curtin
    Genetic Epidemiology, University of Utah School of Medicine, Salt Lake City, UT 84109, USA
    Cancer Epidemiol Biomarkers Prev 18:616-21. 2009
    ..K. case-control cohorts (Sheffield and Leeds) and a U.S. case-control study of CRC cases from high-risk Utah pedigrees...
  56. ncbi request reprint A genealogical assessment of heritable predisposition to aneurysms
    Lisa A Cannon Albright
    Department of Medical Informatics, University of Utah School of Medicine, Salt Lake City, Utah, USA
    J Neurosurg 99:637-43. 2003
    ....
  57. ncbi request reprint High-risk melanoma susceptibility genes and pancreatic cancer, neural system tumors, and uveal melanoma across GenoMEL
    Alisa M Goldstein
    Genetic Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, Maryland 20892 7236, USA
    Cancer Res 66:9818-28. 2006
    ..This GenoMEL study provides the most extensive characterization of mutations in high-risk melanoma susceptibility genes in families with three or more melanoma patients yet available...

Research Grants21

  1. IDENTIFICATION OF MELANOMA PREDISPOSITION LOCI
    Lisa Cannon Albright; Fiscal Year: 2005
    ..abstract_text> ..
  2. IDENTIFICATION OF MELANOMA PREDISPOSITION LOCI
    Lisa Cannon Albright; Fiscal Year: 2006
    ..abstract_text> ..
  3. Analysis of the Familial Component to Disease in a Biomedical Resource w/Link...
    Lisa Cannon Albright; Fiscal Year: 2007
    ..component to many health and disease related traits not previously studied, and will eventually lead to the identification and understanding of disease predisposition, risk-modifying, and disease-associated and health-associated genes ..
  4. IDENTIFICATION OF MELANOMA PREDISPOSITION LOCI
    Lisa Cannon Albright; Fiscal Year: 2007
    ..abstract_text> ..
  5. Analysis of the Familial Component to Disease in a Biomedical Resource w/Link...
    Lisa Cannon Albright; Fiscal Year: 2009
    ..component to many health and disease related traits not previously studied, and will eventually lead to the identification and understanding of disease predisposition, risk-modifying, and disease-associated and health-associated genes ..
  6. IDENTIFICATION OF GENES PREDISPOSING TO PELVIC FLOOR DISORDERS
    Lisa Cannon Albright; Fiscal Year: 2009
    ..Someday, identification of these high risk populations may be as general as familial risk, or as specific as specific gene screening. ..
  7. Analysis of the Familial Component to Disease in a Biomedical Resource w/Link...
    LISA CANNON ALBRIGHT; Fiscal Year: 2010
    ..component to many health and disease related traits not previously studied, and will eventually lead to the identification and understanding of disease predisposition, risk-modifying, and disease-associated and health-associated genes ..
  8. IDENTIFICATION OF MELANOMA PREDISPOSITION LOCI
    Lisa Cannon Albright; Fiscal Year: 2004
    ..abstract_text> ..
  9. Mapping and Cloning Prostate Cancer Predisposition Loci
    Lisa Cannon Albright; Fiscal Year: 2004
    ..This proposal supports the University of Utah high-risk pedigree collection and analysis, and some Myriad genotyping effort towards this goal. ..
  10. IDENTIFICATION OF MELANOMA PREDISPOSITION LOCI
    Lisa Cannon Albright; Fiscal Year: 2003
    ..abstract_text> ..
  11. MAPPING INTRACRANIAL ANEURYSM SUSCEPTIBILITY LOCI
    Lisa Cannon Albright; Fiscal Year: 1999
    ....
  12. MAPPING INTRACRANIAL ANEURYSM SUSCEPTIBILITY LOCI
    Lisa Cannon Albright; Fiscal Year: 2000
    ....
  13. Mapping and Cloning Prostate Cancer Predisposition Loci
    Lisa Cannon Albright; Fiscal Year: 2001
    ..This proposal supports the University of Utah high-risk pedigree collection and analysis, and some Myriad genotyping effort towards this goal. ..
  14. MAPPING INTRACRANIAL ANEURYSM SUSCEPTIBILITY LOCI
    Lisa Cannon Albright; Fiscal Year: 2000
    ....
  15. MAPPING INTRACRANIAL ANEURYSM SUSCEPTIBILITY LOCI
    Lisa Cannon Albright; Fiscal Year: 2001
    ....
  16. Mapping and Cloning Prostate Cancer Predisposition Loci
    Lisa Cannon Albright; Fiscal Year: 2002
    ..This proposal supports the University of Utah high-risk pedigree collection and analysis, and some Myriad genotyping effort towards this goal. ..
  17. Mapping and Cloning Prostate Cancer Predisposition Loci
    Lisa Cannon Albright; Fiscal Year: 2002
    ..This proposal supports the University of Utah high-risk pedigree collection and analysis, and some Myriad genotyping effort towards this goal. ..
  18. Mapping and Cloning Prostate Cancer Predisposition Loci
    Lisa Cannon Albright; Fiscal Year: 2003
    ..This proposal supports the University of Utah high-risk pedigree collection and analysis, and some Myriad genotyping effort towards this goal. ..
  19. IDENTIFICATION OF GENES PREDISPOSING TO PELVIC FLOOR DISORDERS
    LISA CANNON ALBRIGHT; Fiscal Year: 2010
    ..Someday, identification of these high risk populations may be as general as familial risk, or as specific as specific gene screening. ..