Research Topics
Species | Michael J CampbellSummaryAffiliation: University of California Country: USA Publications
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Publications
Antiproliferative activity of Chinese medicinal herbs on breast cancer cells in vitroMichael J Campbell
Department of Surgery and Comprehensive Cancer Center, University of California, San Francisco, CA, USA
Anticancer Res 22:3843-52. 2002..These results indicate that many of the herbs used in traditional Chinese medicine for the treatment of cancer have significant growth inhibitory effects on breast cancer cells in vitro...
Epithelial and fibroblast cell lines derived from a spontaneous mammary carcinoma in a MMTV/neu transgenic mouseMichael J Campbell
Department of Surgery, University of California San Francisco Mount Zion Medical Center, 1600 Divisadero, San Francisco, CA 94115, USA
In Vitro Cell Dev Biol Anim 38:326-33. 2002..In addition, the tumor-derived fibroblast line may be useful for studying tumor-stromal cell interactions...
Breast cancer growth prevention by statinsMichael J Campbell
Department of Surgery, University of California San Francisco Mt Zion Medical Center, Room C342, 1600 Divisadero, San Francisco, CA 94115, USA
Cancer Res 66:8707-14. 2006..These findings provide supporting rationale for future statin trials in breast cancer patients...
Immune dysfunction and micrometastases in women with breast cancerMichael J Campbell
Department of Surgery, University of California, San Francisco, CA 94115, USA
Breast Cancer Res Treat 91:163-71. 2005..These dysregulated T cell responses did not correlate with age, stage of disease, or nodal status. However, we did observe a correlation between number of micrometastases in the bone marrow and T cell responsiveness...
Nordihydroguaiaretic acid (NDGA), an inhibitor of the HER2 and IGF-1 receptor tyrosine kinases, blocks the growth of HER2-overexpressing human breast cancer cellsMarianna Zavodovskaya
Diabetes and Endocrine Research, University of California, San Francisco Mt Zion Medical Center, San Francisco, California, USA
J Cell Biochem 103:624-35. 2008..These studies suggest that NDGA may have therapeutic benefits in HER2-positive, tamoxifen resistant, breast cancers in humans...
Elevated Levels of Proliferating and Recently Migrated Tumor-associated Macrophages Confer Increased Aggressiveness and Worse Outcomes in Breast CancerRita A Mukhtar
Department of Surgery, University of California, San Francisco, CA, USA
Ann Surg Oncol 19:3979-86. 2012..The heterodimeric S100A8/S100A9 complex plays a role in inflammation and is increased in several cancer types...
Elevated PCNA+ tumor-associated macrophages in breast cancer are associated with early recurrence and non-Caucasian ethnicityRita A Mukhtar
University of California, San Francisco, San Francisco, CA, USA
Breast Cancer Res Treat 130:635-44. 2011..These findings implicate immune function in the development of aggressive breast cancer and suggest a possible link between SES and the inflammatory response...
In vitro anticancer activity of twelve Chinese medicinal herbsMark Shoemaker
Department of Surgery, University of California, San Francisco, CA 94115, USA
Phytother Res 19:649-51. 2005....
Diarylureas are small-molecule inhibitors of insulin-like growth factor I receptor signaling and breast cancer cell growthKarissa L Gable
Diabetes and Endocrine Research University of California, San Francisco Mt Zion Medical Center, Box 1616, San Francisco, CA 94143 1616, USA
Mol Cancer Ther 5:1079-86. 2006..p. injection thrice a week) reduced the growth rate of MCNeuA cells implanted into mice. These studies indicate that diaryl urea compounds are potential new agents to test in the treatment of breast and other IGF-I-sensitive cancers...
Proliferating macrophages associated with high grade, hormone receptor negative breast cancer and poor clinical outcomeMichael J Campbell
Department of Surgery, University of California, San Francisco, CA, USA
Breast Cancer Res Treat 128:703-11. 2011..015). The presence of promacs in human breast cancer may serve as a prognostic indicator for poor outcomes and early recurrence and serve as a potential cellular target for novel therapeutic interventions...
Tumor-associated macrophages in breast cancer as potential biomarkers for new treatments and diagnosticsRita A Mukhtar
Department of Surgery, University of California, San Francisco, Box 1710 UCSF, San Francisco, CA 94143 1710, USA
Expert Rev Mol Diagn 11:91-100. 2011..These TAMs are found in high-risk breast cancers, making them an important therapeutic target to explore. Improved techniques for identifying TAMs should translate into clinical applications for prognosis and treatment...
Tid1, the human homologue of a Drosophila tumor suppressor, reduces the malignant activity of ErbB-2 in carcinoma cellsSung Woo Kim
Department of Immunology, The Scripps Research Institute, La Jolla, California 92037, USA
Cancer Res 64:7732-9. 2004..Moreover, the cochaperonic and regulatory functions of Tid1 on HSP70 most likely play an essential role in this antitumor function of Tid1 in carcinoma cells...
