C Campbell

Summary

Affiliation: University of Minnesota
Country: USA

Publications

  1. ncbi request reprint Mammalian mitochondria possess homologous DNA recombination activity
    B Thyagarajan
    Department of Pharmacology, University of Minnesota Medical School, Minneapolis, Minnesota 55455, USA
    J Biol Chem 271:27536-43. 1996
  2. pmc Antisense-mediated decrease in DNA ligase III expression results in reduced mitochondrial DNA integrity
    U Lakshmipathy
    Department of Pharmacology, University of Minnesota Medical School, 6-120 Jackson Hall, 321 Church Street SE, Minneapolis, MN 55455, USA
    Nucleic Acids Res 29:668-76. 2001
  3. pmc Mitochondrial DNA ligase III function is independent of Xrcc1
    U Lakshmipathy
    University of Minnesota Medical School, Department of Pharmacology, 6 120 Jackson Hall, 321 Church Street SE, Minneapolis, MN 55455, USA
    Nucleic Acids Res 28:3880-6. 2000
  4. pmc An alternate form of Ku80 is required for DNA end-binding activity in mammalian mitochondria
    G Coffey
    Department of Pharmacology, University of Minnesota Medical School, 6 120 Jackson Hall, 321 Church Street S E, Minneapolis, MN 55455, USA
    Nucleic Acids Res 28:3793-800. 2000
  5. pmc Mitochondrial DNA ligase function in Saccharomyces cerevisiae
    S L Donahue
    Department of Pharmacology, University of Minnesota Medical School, 6-120 Jackson Hall, 321 Church Street SE, Minneapolis, MN 55455, USA
    Nucleic Acids Res 29:1582-9. 2001
  6. ncbi request reprint Deficient DNA end joining activity in extracts from fanconi anemia fibroblasts
    R Lundberg
    Department of Pharmacology, University of Minnesota Medical School, Minneapolis, Minnesota 55455, USA
    J Biol Chem 276:9543-9. 2001
  7. pmc The human DNA ligase III gene encodes nuclear and mitochondrial proteins
    U Lakshmipathy
    Department of Pharmacology, University of Minnesota Medical School, Minneapolis, Minnesota 55455, USA
    Mol Cell Biol 19:3869-76. 1999

Collaborators

  • U Lakshmipathy
  • S L Donahue
  • R Lundberg
  • G Coffey
  • B Thyagarajan
  • B E Corner
  • M Mavinakere
  • L Bordone
  • R A Padua

Detail Information

Publications7

  1. ncbi request reprint Mammalian mitochondria possess homologous DNA recombination activity
    B Thyagarajan
    Department of Pharmacology, University of Minnesota Medical School, Minneapolis, Minnesota 55455, USA
    J Biol Chem 271:27536-43. 1996
    ..The presence of homologous recombination activity within mammalian mitochondrial extracts suggests that this process is involved in mitochondrial DNA repair...
  2. pmc Antisense-mediated decrease in DNA ligase III expression results in reduced mitochondrial DNA integrity
    U Lakshmipathy
    Department of Pharmacology, University of Minnesota Medical School, 6-120 Jackson Hall, 321 Church Street SE, Minneapolis, MN 55455, USA
    Nucleic Acids Res 29:668-76. 2001
    ..We conclude that DNA ligase III is essential for the proper maintenance of mtDNA in cultured mammalian somatic cells...
  3. pmc Mitochondrial DNA ligase III function is independent of Xrcc1
    U Lakshmipathy
    University of Minnesota Medical School, Department of Pharmacology, 6 120 Jackson Hall, 321 Church Street SE, Minneapolis, MN 55455, USA
    Nucleic Acids Res 28:3880-6. 2000
    ..Thus, mitochondrial DNA ligase III function is independent of the Xrcc1 protein...
  4. pmc An alternate form of Ku80 is required for DNA end-binding activity in mammalian mitochondria
    G Coffey
    Department of Pharmacology, University of Minnesota Medical School, 6 120 Jackson Hall, 321 Church Street S E, Minneapolis, MN 55455, USA
    Nucleic Acids Res 28:3793-800. 2000
    ..These data are consistent with the hypothesis that a C-terminally truncated form of Ku80 is localized in mammalian mitochondria where it functions in a DNA end-binding activity...
  5. pmc Mitochondrial DNA ligase function in Saccharomyces cerevisiae
    S L Donahue
    Department of Pharmacology, University of Minnesota Medical School, 6-120 Jackson Hall, 321 Church Street SE, Minneapolis, MN 55455, USA
    Nucleic Acids Res 29:1582-9. 2001
    ..These results support the conclusion that yeast rely upon a single DNA ligase, Cdc9p, to carry out mitochondrial DNA replication and recovery from both spontaneous and induced mitochondrial DNA damage...
  6. ncbi request reprint Deficient DNA end joining activity in extracts from fanconi anemia fibroblasts
    R Lundberg
    Department of Pharmacology, University of Minnesota Medical School, Minneapolis, Minnesota 55455, USA
    J Biol Chem 276:9543-9. 2001
    ..Taken together, these results suggest that the FA fibroblast extracts have a deficiency in a DNA end joining process that is distinct from the DNA-PK/Ku-dependent nonhomologous DNA end joining pathway...
  7. pmc The human DNA ligase III gene encodes nuclear and mitochondrial proteins
    U Lakshmipathy
    Department of Pharmacology, University of Minnesota Medical School, Minneapolis, Minnesota 55455, USA
    Mol Cell Biol 19:3869-76. 1999
    ..DNA ligase plays a central role in DNA replication, recombination, and DNA repair. Thus, identification of a mitochondrial form of this enzyme provides a tool with which to dissect mammalian mitochondrial genome dynamics...