Arezoo Campbell

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Aluminum-induced oxidative events in cell lines: glioma are more responsive than neuroblastoma
    A Campbell
    Center for Occupational and Environmental Health, Department of Community and Environmental Medicine, University of California Irvine, 92697 1825, USA
    Free Radic Biol Med 26:1166-71. 1999
  2. ncbi request reprint Particulate matter in polluted air may increase biomarkers of inflammation in mouse brain
    A Campbell
    Department of Community and Environmental Medicine, University of California, Irvine, CA 92697 1825, USA
    Neurotoxicology 26:133-40. 2005
  3. ncbi request reprint Pro-inflammatory effects of aluminum in human glioblastoma cells
    Arezoo Campbell
    Department of Community and Environmental Medicine, Center for Occupational and Environmental Health, University of California Irvine, Irvine, CA 92697 1820, USA
    Brain Res 933:60-5. 2002
  4. ncbi request reprint The potential role of aluminium in Alzheimer's disease
    Arezoo Campbell
    Department of Community and Environmental Medicine, College of Medicine, Faculty Research Facility, University of California, Irvine, CA 92697 1825, USA
    Nephrol Dial Transplant 17:17-20. 2002
  5. ncbi request reprint Inflammation, neurodegenerative diseases, and environmental exposures
    Arezoo Campbell
    Department of Community and Environmental Medicine, University of California, 92697 1825, USA
    Ann N Y Acad Sci 1035:117-32. 2004
  6. ncbi request reprint Mechanisms by which metals promote events connected to neurodegenerative diseases
    A Campbell
    Department of Community and Environmental Medicine, University of California, Irvine, Irvine, CA 92697 1825, USA
    Brain Res Bull 55:125-32. 2001
  7. ncbi request reprint beta-amyloid: friend or foe
    A Campbell
    Department of Community and Environmental Medicine, University of California, CA, USA
    Med Hypotheses 56:388-91. 2001
  8. ncbi request reprint Chronic exposure to aluminum in drinking water increases inflammatory parameters selectively in the brain
    A Campbell
    Department of Community and Environmental Medicine, Center for Occupational and Environmental Health Sciences, Irvine, California 92697, USA
    J Neurosci Res 75:565-72. 2004
  9. ncbi request reprint Aluminum and copper in drinking water enhance inflammatory or oxidative events specifically in the brain
    Angelica Becaria
    Department of Community and Environmental Medicine, Center for Occupational and Environmental Health Sciences, University of California, Irvine, Irvine, CA 92697 1825, USA
    J Neuroimmunol 176:16-23. 2006
  10. ncbi request reprint Aluminum and copper interact in the promotion of oxidative but not inflammatory events: implications for Alzheimer's disease
    Angelica Becaria
    Department of Community and Environmental Medicine, Center for Occupational and Environmental Health, University of California Irvine, 92697 1820, USA
    J Alzheimers Dis 5:31-8. 2003

Detail Information

Publications24

  1. ncbi request reprint Aluminum-induced oxidative events in cell lines: glioma are more responsive than neuroblastoma
    A Campbell
    Center for Occupational and Environmental Health, Department of Community and Environmental Medicine, University of California Irvine, 92697 1825, USA
    Free Radic Biol Med 26:1166-71. 1999
    ..Thus, it is possible that the cerebral target following an acute exposure to aluminum may be glial rather than neuronal...
  2. ncbi request reprint Particulate matter in polluted air may increase biomarkers of inflammation in mouse brain
    A Campbell
    Department of Community and Environmental Medicine, University of California, Irvine, CA 92697 1825, USA
    Neurotoxicology 26:133-40. 2005
    ..These data indicate that components of inhaled particulate matter may trigger a proinflammatory response in nervous tissue that could contribute to the pathophysiology of neurodegenerative diseases...
  3. ncbi request reprint Pro-inflammatory effects of aluminum in human glioblastoma cells
    Arezoo Campbell
    Department of Community and Environmental Medicine, Center for Occupational and Environmental Health, University of California Irvine, Irvine, CA 92697 1820, USA
    Brain Res 933:60-5. 2002
    ..This may reflect the ability of the cells to discern different stress factors and thus orchestrate an innate immune response profile distinct to each immunogen...
  4. ncbi request reprint The potential role of aluminium in Alzheimer's disease
    Arezoo Campbell
    Department of Community and Environmental Medicine, College of Medicine, Faculty Research Facility, University of California, Irvine, CA 92697 1825, USA
    Nephrol Dial Transplant 17:17-20. 2002
    ..The results discussed here have broad implications for the role played by aluminium and other metals in neurodegenerative diseases, and suggest that long-term exposure to supra-physiological amounts these metals should be avoided...
  5. ncbi request reprint Inflammation, neurodegenerative diseases, and environmental exposures
    Arezoo Campbell
    Department of Community and Environmental Medicine, University of California, 92697 1825, USA
    Ann N Y Acad Sci 1035:117-32. 2004
    ..These factors may enhance existing age-related inflammation in the central nervous system and thus accelerate neuronal toxicity...
  6. ncbi request reprint Mechanisms by which metals promote events connected to neurodegenerative diseases
    A Campbell
    Department of Community and Environmental Medicine, University of California, Irvine, Irvine, CA 92697 1825, USA
    Brain Res Bull 55:125-32. 2001
    ..This review addresses mechanisms by which endogenous or environmental factors, through interaction with redox active metals, may initiate a common cascade of events terminating in neurodegeneration...
  7. ncbi request reprint beta-amyloid: friend or foe
    A Campbell
    Department of Community and Environmental Medicine, University of California, CA, USA
    Med Hypotheses 56:388-91. 2001
    ..Here, a hypothesis is presented that the protein may indeed be protective and that a potential role for beta amyloid in innate immunity may exist...
  8. ncbi request reprint Chronic exposure to aluminum in drinking water increases inflammatory parameters selectively in the brain
    A Campbell
    Department of Community and Environmental Medicine, Center for Occupational and Environmental Health Sciences, Irvine, California 92697, USA
    J Neurosci Res 75:565-72. 2004
    ....
  9. ncbi request reprint Aluminum and copper in drinking water enhance inflammatory or oxidative events specifically in the brain
    Angelica Becaria
    Department of Community and Environmental Medicine, Center for Occupational and Environmental Health Sciences, University of California, Irvine, Irvine, CA 92697 1825, USA
    J Neuroimmunol 176:16-23. 2006
    ..Results suggest that although Al or Cu may independently initiate inflammatory or oxidative events, they may function cooperatively to increase APP levels...
  10. ncbi request reprint Aluminum and copper interact in the promotion of oxidative but not inflammatory events: implications for Alzheimer's disease
    Angelica Becaria
    Department of Community and Environmental Medicine, Center for Occupational and Environmental Health, University of California Irvine, 92697 1820, USA
    J Alzheimers Dis 5:31-8. 2003
    ..Thus the ability of aluminum to promote inflammatory processes does not depend on an increase ROS production induced by interaction with transition metals...
  11. pmc Inhaled ultrafine particulate matter affects CNS inflammatory processes and may act via MAP kinase signaling pathways
    M T Kleinman
    Department of Community and Environmental Medicine, University of California Irvine, Irvine, CA 92697, USA
    Toxicol Lett 178:127-30. 2008
    ..This suggests that the signaling pathway by which these transcription factors are activated involves the activation of JNK...
  12. ncbi request reprint Retardation of brain aging by chronic treatment with melatonin
    S C Bondy
    Department of Community and Environmental Medicine, University of California, Irvine, 92697 1825, USA
    Ann N Y Acad Sci 1035:197-215. 2004
    ..This report summarizes the progress made in this area...
  13. ncbi request reprint Aluminum as a toxicant
    A Becaria
    Department of Community and Environmental Medicine, Center for Occupational and Environmental Health Sciences, Irvine, CA 92697 1820, USA
    Toxicol Ind Health 18:309-20. 2002
    ..This review encompasses the general toxicology of aluminum with emphasis on the potential mechanisms by which it may accelerate the progression of chronic age-related neurodegenerative disorders...
  14. ncbi request reprint Modulation of oxidative events by multivalent manganese complexes in brain tissue
    D Hamai
    Department of Community and Environmental Medicine, Center for Occupational and Environmental Health, University of California, Irvine, Irvine, CA 92697 1825, USA
    Free Radic Biol Med 31:763-8. 2001
    ..Such findings of the potent effects of trace amounts of trivalent cations upon Mn2+-related free radical generation offer resolution of earlier disparate findings concerning the oxidative character of manganese...
  15. ncbi request reprint The chemistry of transition metals in relation to their potential role in neurodegenerative processes
    D Hamai
    Department of Community and Environmental Medicine, Center for Occupational and Environmental Health, University of California, Irvine 92697 1820, USA
    Curr Top Med Chem 1:541-51. 2001
    ....
  16. ncbi request reprint Chronic exposure to low levels of aluminum alters cerebral cell signaling in response to acute MPTP administration
    H Li
    Department of Community and Environmental Medicine, Center for Occupational and Environmental Health, University of California, Irvine, California 92697 1825, USA
    Toxicol Ind Health 23:515-24. 2007
    ..However, no interaction in alteration of monoamine levels was found between Al and MPTP...
  17. ncbi request reprint Differential toxicity of aluminum salts in human cell lines of neural origin: implications for neurodegeneration
    A Campbell
    Department of Community and Environmental Medicine, Center for Occupational and Environmental Health, University of California, Irvine 92697-1820, USA
    Neurotoxicology 22:63-71. 2001
    ..It is possible that the principal neurotoxic target of the metal is glial and when these cells are in a compromised state, this may secondarily impact the neuronal population and thus eventually lead to neurodegeneration...
  18. doi request reprint Age-related differences in the response of the brain to dietary melatonin
    Arezoo Campbell
    Department of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, CA, 91766 1854, USA
    Age (Dordr) 36:49-55. 2014
    ..The results illustrate that previously reported changes in gene expression following melatonin treatment need not be closely paralleled by corresponding changes in protein content. ..
  19. ncbi request reprint Developmental neurotoxicology
    Stephen C Bondy
    Department of Community and Environmental Medicine, Center for Occupational and Environmental Health, University of California, Irvine, Irvine, California 92967 1820, USA
    J Neurosci Res 81:605-12. 2005
    ..The rate of brain aging may be influenced by events taking place in embryogenesis, following a prolonged asymptomatic period. The potential for appearance of adverse effects after prolonged latent periods is underscored...
  20. ncbi request reprint Reduced basal levels and enhanced LPS response of IL-6 mRNA in aged mice
    K Sharman
    Center for Occupational and Environmental Health, Department of Community and Environmental Medicine, University of California, Irvine, CA 92697-1825, USA
    J Gerontol A Biol Sci Med Sci 56:B520-3. 2001
    ..These data indicate that the aging process may predispose animals to an exaggerated and potentially harmful inflammatory response...
  21. ncbi request reprint The role of aluminum and copper on neuroinflammation and Alzheimer's disease
    Arezoo Campbell
    Western University of Health Sciences, Department of Pharmaceutical Sciences, Pomona, CA 91766, USA
    J Alzheimers Dis 10:165-72. 2006
    ..Since inflammatory events are reported to be upregulated in the AD brain, this may be one of the mechanisms by which the metals potentiate neurodegeneration...
  22. ncbi request reprint The significance of environmental factors in the etiology of Alzheimer's disease
    William B Grant
    12 Sir Francis Wyatt Place, Newport News, VA 23606 3660, USA
    J Alzheimers Dis 4:179-89. 2002
    ..Diet, aluminum, and viral infections may increase the prevalence of AD by eliciting inflammation, which may cause the neurological damage that results in AD...
  23. doi request reprint Particulate matter, oxidative stress and neurotoxicity
    Sheba M J MohanKumar
    Department of Pharmacology and Toxicology, Michigan State University, E Lansing, MI, USA
    Neurotoxicology 29:479-88. 2008
    ..These were recently presented at two 2007 symposia sponsored by the Society of Toxicology (Charlotte, NC) and the International Neurotoxicology Association (Monterey, CA)...
  24. ncbi request reprint Incubation of nerve endings with a physiological concentration of Abeta1-42 activates CaV2.2(N-Type)-voltage operated calcium channels and acutely increases glutamate and noradrenaline release
    Joseph A Bobich
    Department of Chemistry, Texas Christian University, Fort Worth, TX 76129, USA
    J Alzheimers Dis 6:243-55. 2004
    ....