WENDY CAMPANA

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Low-Density Lipoprotein Receptor Related protein-1 (LRP1)-Dependent Cell Signaling Promotes Neurotrophic Activity in Embryonic Sensory Neurons
    Kazuyo Yamauchi
    Department of Anesthesiology, School of Medicine, University of California San Diego, La Jolla, California, United States of America Department of Orthopedic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan
    PLoS ONE 8:e75497. 2013
  2. ncbi request reprint Prosaposin-derived peptides enhanced sprouting of sensory neurons in vitro and induced sprouting at motor endplates in vivo
    W M Campana
    Department of Neuroscience, University of California, San Diego, La Jolla, USA
    J Peripher Nerv Syst 5:126-30. 2000
  3. ncbi request reprint Identification of PINCH in Schwann cells and DRG neurons: shuttling and signaling after nerve injury
    W Marie Campana
    Department of Anesthesiology, University of California, San Diego, La Jolla, California 92093 0629, USA
    Glia 41:213-23. 2003
  4. ncbi request reprint Exogenous erythropoietin protects against dorsal root ganglion apoptosis and pain following peripheral nerve injury
    W Marie Campana
    Department of Anesthesiology, University of California, San Diego School of Medicine, 9500 Gilman Drive, La Jolla, CA 92093 0629, USA
    Eur J Neurosci 18:1497-506. 2003
  5. ncbi request reprint Erythropoietin reduces Schwann cell TNF-alpha, Wallerian degeneration and pain-related behaviors after peripheral nerve injury
    W Marie Campana
    Department of Anesthesiology, University of California, San Diego School of Medicine, La Jolla, CA, USA
    Eur J Neurosci 23:617-26. 2006
  6. ncbi request reprint The low-density lipoprotein receptor-related protein is a pro-survival receptor in Schwann cells: possible implications in peripheral nerve injury
    W Marie Campana
    Department of Anesthesiology, University of California, San Diego School of Medicine, La Jolla, California 92093 0629, USA
    J Neurosci 26:11197-207. 2006
  7. pmc Schwann cells: activated peripheral glia and their role in neuropathic pain
    Wendy Marie Campana
    Department of Anesthesiology, University of California, San Diego, La Jolla, CA 92093 0629, USA
    Brain Behav Immun 21:522-7. 2007
  8. ncbi request reprint Activation of p38 mitogen-activated protein kinase in spinal microglia is a critical link in inflammation-induced spinal pain processing
    Camilla I Svensson
    Department of Anesthesiology, University of California, San Diego, La Jolla, California, USA
    J Neurochem 86:1534-44. 2003

Detail Information

Publications8

  1. pmc Low-Density Lipoprotein Receptor Related protein-1 (LRP1)-Dependent Cell Signaling Promotes Neurotrophic Activity in Embryonic Sensory Neurons
    Kazuyo Yamauchi
    Department of Anesthesiology, School of Medicine, University of California San Diego, La Jolla, California, United States of America Department of Orthopedic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan
    PLoS ONE 8:e75497. 2013
    ..Collectively, these findings identify LRP1 as a novel and perhaps essential trophic molecule for sensory neuronal survival and development. ..
  2. ncbi request reprint Prosaposin-derived peptides enhanced sprouting of sensory neurons in vitro and induced sprouting at motor endplates in vivo
    W M Campana
    Department of Neuroscience, University of California, San Diego, La Jolla, USA
    J Peripher Nerv Syst 5:126-30. 2000
    ..Our results indicate that prosaptides are potent neuritogenic factors for both sensory and motor neurons of adult peripheral nerve...
  3. ncbi request reprint Identification of PINCH in Schwann cells and DRG neurons: shuttling and signaling after nerve injury
    W Marie Campana
    Department of Anesthesiology, University of California, San Diego, La Jolla, California 92093 0629, USA
    Glia 41:213-23. 2003
    ..Taken together, these results indicate that PINCH is an abundant shuttling/signaling protein in Schwann cells and DRG neurons...
  4. ncbi request reprint Exogenous erythropoietin protects against dorsal root ganglion apoptosis and pain following peripheral nerve injury
    W Marie Campana
    Department of Anesthesiology, University of California, San Diego School of Medicine, 9500 Gilman Drive, La Jolla, CA 92093 0629, USA
    Eur J Neurosci 18:1497-506. 2003
    ..The findings link anti-apoptosis activities of Epo/EpoR/JAK2 in DRG neurons capable of inducing protracted pain states with reductions in pain behaviours, and therefore support a role for Epo therapy in the treatment of neuropathic pain...
  5. ncbi request reprint Erythropoietin reduces Schwann cell TNF-alpha, Wallerian degeneration and pain-related behaviors after peripheral nerve injury
    W Marie Campana
    Department of Anesthesiology, University of California, San Diego School of Medicine, La Jolla, CA, USA
    Eur J Neurosci 23:617-26. 2006
    ....
  6. ncbi request reprint The low-density lipoprotein receptor-related protein is a pro-survival receptor in Schwann cells: possible implications in peripheral nerve injury
    W Marie Campana
    Department of Anesthesiology, University of California, San Diego School of Medicine, La Jolla, California 92093 0629, USA
    J Neurosci 26:11197-207. 2006
    ..Schwann cell death was induced in vivo by injecting the LRP-1 antagonist, receptor-associated protein, into axotomy sites in adult rats. These results support a model in which LRP-1 functions as a pro-survival receptor in Schwann cells...
  7. pmc Schwann cells: activated peripheral glia and their role in neuropathic pain
    Wendy Marie Campana
    Department of Anesthesiology, University of California, San Diego, La Jolla, CA 92093 0629, USA
    Brain Behav Immun 21:522-7. 2007
    ..Aberrations in Schwann cell biology may lie at the foundation of neuropathic pain and represent an exciting target for therapeutic intervention...
  8. ncbi request reprint Activation of p38 mitogen-activated protein kinase in spinal microglia is a critical link in inflammation-induced spinal pain processing
    Camilla I Svensson
    Department of Anesthesiology, University of California, San Diego, La Jolla, California, USA
    J Neurochem 86:1534-44. 2003
    ..Taken together, these results indicate that spinal p38 MAPK is involved in inflammation-induced pain and that activated spinal microglia play a direct role in spinal nociceptive processing...

Research Grants7

  1. Epo-dependent JAK2 Signaling in Painful Neuropathy
    WENDY CAMPANA; Fiscal Year: 2003
    ..The experiments will provide new information on the basic mechanisms of nerve injury and pain, and there from, new rationale for development of novel neuroprotective strategies for preventing chronic neuropathic pain. ..
  2. Epo-dependent JAK2 Signaling in Painful Neuropathy
    WENDY CAMPANA; Fiscal Year: 2006
    ..The experiments will provide new information on the basic mechanisms of nerve injury and pain, and there from, new rationale for development of novel neuroprotective strategies for preventing chronic neuropathic pain. ..
  3. LRP-1 is a multifunctional regulator during peripheral nerve injury and pain.
    WENDY CAMPANA; Fiscal Year: 2009
    ..This grant application seeks to understand the molecular mechanisms underlying peripheral nerve injury and with that understanding, build a foundation in which we can develop novel therapeutics for chronic pain. ..
  4. LRP-1 is a multifunctional regulator during peripheral nerve injury and pain.
    Wendy M Campana; Fiscal Year: 2010
    ..This grant application seeks to understand the molecular mechanisms underlying peripheral nerve injury and with that understanding, build a foundation in which we can develop novel therapeutics for chronic pain. ..