Research Topics
Genomes and GenesSpecies | Clifton CallawaySummaryAffiliation: University of Pittsburgh Country: USA Publications
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Publications
Epinephrine for cardiac arrestClifton W Callaway
Department of Emergency Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA
Curr Opin Cardiol 28:36-42. 2013..However, the dose, timing and indications for epinephrine use are based on limited animal data. Recent studies question whether epinephrine provides any overall benefit for patients...
Receiving hospital characteristics associated with survival after out-of-hospital cardiac arrestClifton W Callaway
Department of Emergency Medicine, University of Pittsburgh, Pittsburgh, PA, USA
Resuscitation 81:524-9. 2010..This study examined whether survival to hospital discharge was related to receiving hospital characteristics, including bed number, capability of performing cardiac catheterization and hospital volume of OOHCA cases...
Waveform analysis of ventricular fibrillation to predict defibrillationClifton W Callaway
University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania 15213, USA
Curr Opin Crit Care 11:192-9. 2005..Quantitative analysis of the ventricular fibrillation waveform may distinguish coarse ventricular fibrillation from fine ventricular fibrillation, allowing more appropriate delivery of rescue shocks...- Brain-derived neurotrophic factor does not improve recovery after cardiac arrest in ratsClifton W Callaway
Department of Emergency Medicine, Safar Center for Resuscitation Research, University of Pittsburgh, Pittsburgh, PA 15213, USA
Neurosci Lett 445:103-7. 2008..These data suggest that increased BDNF levels are not sufficient to explain the beneficial effects of mild hypothermia after cardiac arrest, and that exogenous BDNF administration does not increase extracellular ERK signaling... - Hypothermia after cardiac arrest does not alter serum inflammatory markersClifton W Callaway
Department of Emergency Medicine, University of Pittsburgh, Pittsburgh, PA, USA
Crit Care Med 36:2607-12. 2008..This study tested whether therapeutic hypothermia altered levels of inflammatory markers in serum... - Current & future direction for the resuscitation of cardiac arrest patientsClifton W Callaway
University of Pittsburgh, USA
JEMS 29:suppl 14-22. 2004 - Usefulness of vasopressin administered with epinephrine during out-of-hospital cardiac arrestClifton W Callaway
Department of Emergency Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
Am J Cardiol 98:1316-21. 2006..Survival duration for subjects admitted to the hospital did not differ between groups. In conclusion, vasopressin administered with epinephrine does not increase the rate of return of spontaneous circulation... - A critical assessment of the out-of-hospital trauma triage guidelines for physiologic abnormalityCraig D Newgard
Department of Emergency Medicine, Center for Policy and Research in Emergency Medicine, Oregon Health and Science University, Portland, Oregon, USA
J Trauma 68:452-62. 2010..We assessed whether more restrictive physiologic criteria would improve the specificity of this triage step without missing high-risk patients... - A randomized comparison of manual, mechanical and high-impulse chest compression in a porcine model of prolonged ventricular fibrillationAmy E Betz
Department of Emergency Medicine, University of Pittsburgh School of Medicine, 230 McKee Place, Suite 400, Pittsburgh, PA 15213, USA
Resuscitation 69:495-501. 2006..We hypothesized that HI (very rapid acceleration of the down-stroke) would produce greater CPPs than MAN or MECH, and that HI would also produce a higher rate of ROSC... - Interruptions in cardiopulmonary resuscitation from paramedic endotracheal intubationHenry E Wang
Department of Emergency Medicine, University of Pittsburgh, Pittsburgh, PA
Ann Emerg Med 54:645-652.e1. 2009..We quantified the frequency and duration of CPR chest compression interruptions associated with paramedic endotracheal intubation efforts during out-of-hospital cardiopulmonary arrest... - Immediate defibrillation versus interventions first in a swine model of prolonged ventricular fibrillationJames J Menegazzi
Department of Emergency Medicine, 230 McKee Place, Suite 400, Pittsburgh, PA 15213, USA
Resuscitation 59:261-70. 2003..We also sought to determine the predictive value of the ScE in determining post-shock outcomes... - Dynamic nature of electrocardiographic waveform predicts rescue shock outcome in porcine ventricular fibrillationChristopher B Lightfoot
Department of Emergency Medicine, Center for Emergency Medicine of Western Pennsylvania, University of Pittsburgh, Pittsburgh, PA 15213, USA
Ann Emerg Med 42:230-41. 2003..In addition, unsuccessful rescue shocks might decrease post-rescue shock ventricular fibrillation waveform organization... - Prehospital serum lactate as a predictor of outcomes in trauma patients: a retrospective observational studyFrancis Guyette
Department of Emergency Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
J Trauma 70:782-6. 2011..Lactate is associated with morbidity and mortality; however, the value of prehospital lactate (pLA) is unknown. Our objective was to determine whether pLA improves identification of mortality and morbidity independent of vital signs... - Hypothermia and ERK activation after cardiac arrestEric S Logue
Department of Emergency Medicine, 230 McKee Place, Suite 400, Pittsburgh, PA 15213, USA
Brain Res 1064:108-18. 2005..These results suggest that hypothermia-induced improvement in outcomes does not require ERK activation... - Body temperature changes are associated with outcomes following in-hospital cardiac arrest and return of spontaneous circulationBrian Suffoletto
University of Pittsburgh, Pittsburgh, PA, United States
Resuscitation 80:1365-70. 2009..We tested the hypothesis that adults who experience temperature lability in the first 24h have worse outcomes compared with those who maintain normothermia... - Angular velocity: a new method to improve prediction of ventricular fibrillation durationLawrence D Sherman
Department of Emergency Medicine, University of Pittsburg School of Medicine, Pittsburgh, PA 15213, USA
Resuscitation 60:79-90. 2004..The combination of ScE and AV can be used in developing strategies for the treatment of VF during the different clinical phases of VF... - Post-resuscitation hemodynamics and relationship to the duration of ventricular fibrillationJames J Menegazzi
Department of Emergency Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
Resuscitation 78:355-8. 2008..We sought to characterize the time-course of these patterns, and to determine whether these differed based on duration of the VF insult... - Near-infrared spectroscopy in post-cardiac arrest patients undergoing therapeutic hypothermiaBrian Suffoletto
Department of Emergency Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States
Resuscitation 83:986-90. 2012..To investigate the relationship between tissue oxygen saturation during a vascular occlusion test with systemic hemodynamics, central and peripheral skin temperature in patients resuscitated from cardiac arrest... - Emergency medical services intervals and survival in trauma: assessment of the "golden hour" in a North American prospective cohortCraig D Newgard
Center for Policy and Research in Emergency Medicine, Department of Emergency Medicine, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239 3098, USA
Ann Emerg Med 55:235-246.e4. 2010..We evaluate the association between emergency medical services (EMS) intervals and mortality among trauma patients with field-based physiologic abnormality... - Method of cold saline storage for prehospital induced hypothermiaMitch Kampmeyer
Department of Emergency Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
Prehosp Emerg Care 13:81-4. 2009..The aim of this study was to determine whether a standard commercial cooler can maintain two 1-L normal saline solution (NSS) bags below 4 degrees C in three different environments... - A trial of an impedance threshold device in out-of-hospital cardiac arrestTom P Aufderheide
Department of Emergency Medicine, Medical College of Wisconsin, Milwaukee, WI 53226, USA
N Engl J Med 365:798-806. 2011..Previous studies have suggested that the use of an ITD during CPR may improve survival rates after cardiac arrest... - Summary of NIH Medical-Surgical Emergency Research Roundtable held on April 30 to May 1, 2009Amy H Kaji
Department of Emergency Medicine, Harbor UCLA Medical Center, 1000 W Carson Street, Box 21, Torrance, CA 90509 2910, USA
Ann Emerg Med 56:522-37. 2010.... - Outcomes of a hospital-wide plan to improve care of comatose survivors of cardiac arrestJon C Rittenberger
Department of Emergency Medicine, University of Pittsburgh, United States
Resuscitation 79:198-204. 2008..We implemented a series of process interventions designed to increase TH use and improve outcomes in patients successfully resuscitated from out-of-hospital cardiac arrest (OHCA) or in-hospital cardiac arrest (IHCA)... - The effect of adenosine A1 receptor antagonism on return of spontaneous circulation and short-term survival in prolonged ventricular fibrillationTimothy J Mader
Department of Emergency Medicine, Baystate Medical Center Tufts University School of Medicine, Boston, Massachusetts, USA
Prehosp Emerg Care 12:352-8. 2008..We have previously shown that ADO A1 receptor (ADOA1R) antagonism hastens the time-dependent decay in VF waveform morphology during the circulatory phase of cardiac arrest... - Risk of cardiopulmonary arrest after acute respiratory compromise in hospitalized patientsHenry E Wang
Department of Emergency Medicine, University of Pittsburgh, 230 McKee Place, Suite 400, Pittsburgh, PA 15213, USA
Resuscitation 79:234-40. 2008..We determined the characteristics and clinical course of hospitalized patients experiencing ARC as well as their risk of developing subsequent CPA... - High-dose diazepam facilitates core cooling during cold saline infusion in healthy volunteersDavid Hostler
University of Pittsburgh, Department of Emergency Medicine, Pittsburgh, PA 15213, USA
Appl Physiol Nutr Metab 34:582-6. 2009.... - Mild hypothermia alters midazolam pharmacokinetics in normal healthy volunteersDavid Hostler
Department of Emergency Medicine, Emergency Responder Human Performance Laboratory, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
Drug Metab Dispos 38:781-8. 2010..Future studies in patients who receive lower levels and a longer duration of hypothermia are warranted... - Survival of verapamil-poisoned rats treated with triiodothyronineMichael J Lynch
Department of Emergency Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
J Med Toxicol 6:94-9. 2010..Despite significant variability in toxicity among individual animals, no statistically significant difference in survival time, heart rate, or MAP was found between groups treated with T3 and those receiving saline... - Increased survival after EMS witnessed cardiac arrest. Observations from the Resuscitation Outcomes Consortium (ROC) Epistry-Cardiac arrestDavid Hostler
University of Pittsburgh, Department of Emergency Medicine, Suite 400A, Pittsburgh, PA 15261, USA
Resuscitation 81:826-30. 2010..We examined EMS witnessed OHCA from the Resuscitation Outcomes Consortium (ROC) to determine the effect of EMS witnessed vs. bystander witnessed and unwitnessed OHCA... - Association between clinical examination and outcome after cardiac arrestJon C Rittenberger
University of Pittsburgh, Department of Emergency Medicine, Pittsburgh, PA 15261, USA
Resuscitation 81:1128-32. 2010..We measured the association between clinical examination findings at hospital arrival, 24, and 72 h after cardiac arrest in a modern intensive care unit setting... - Effect of real-time feedback during cardiopulmonary resuscitation outside hospital: prospective, cluster-randomised trialDavid Hostler
Department of Emergency Medicine, University of Pittsburgh, 3600 Forbes Ave, Suite 400A, Pittsburgh, PA 15261, USA
BMJ 342:d512. 2011..To investigate whether real-time audio and visual feedback during cardiopulmonary resuscitation outside hospital increases the proportion of subjects who achieved prehospital return of spontaneous circulation... - Association of delay to first intervention with return of spontaneous circulation in a swine model of cardiac arrestJon C Rittenberger
University of Pittsburgh, Department of Emergency Medicine, Pittsburgh, PA 15213, USA
Resuscitation 73:154-60. 2007..We sought to determine the duration of circulatory arrest after which maximal drug treatment and a rescue shock would fail to achieve return of spontaneous circulation (ROSC)... - Hyponatremia in runners requiring on-site medical treatment at a single marathonMargaret Hsieh
Department of Emergency Medicine, University of Pittsburgh, Pittsburgh, PA, USA
Med Sci Sports Exerc 34:185-9. 2002.... - Feasibility of external cranial cooling during out-of-hospital cardiac arrestClifton W Callaway
Department of Emergency Medicine, University of Pittsburgh, 230 McKee Place, Suite 400, Pittsburgh, PA 15213, USA
Resuscitation 52:159-65. 2002..However, most cardiac arrest victims are spontaneously mildly hypothermic and preventing rewarming may provide some of the desired benefits of cerebral hypothermia... - Ventricular fibrillation scaling exponent can guide timing of defibrillation and other therapiesJames J Menegazzi
Department of Emergency Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
Circulation 109:926-31. 2004..The scaling exponent (ScE) of the ventricular fibrillation (VF) waveform correlates with duration of VF and predicts defibrillation outcome. We compared 4 therapeutic approaches to the treatment of VF of various durations... - Admission hypothermia and outcome after major traumaHenry E Wang
Department of Emergency Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
Crit Care Med 33:1296-301. 2005..The goal of this study was to evaluate the independent association between admission hypothermia and mortality after major trauma, with adjustment for clinical confounders... - Vasopressin administered with epinephrine is associated with a return of a pulse in out-of-hospital cardiac arrestFrancis X Guyette
Department of Emergency Medicine, University of Pittsburgh School of Medicine, 230 McKee Place, Suite 400, Pittsburgh, PA 15213, USA
Resuscitation 63:277-82. 2004..85; 1.71, 8.65) than subjects treated with epinephrine alone. CONCLUSIONS: There is an association between using vasopressin in combination with epinephrine and restoration of circulation after out-of-hospital cardiac arrest... - Differential effects of out-of-hospital interventions on short- and long-term survival after cardiopulmonary arrestHenry E Wang
Department of Emergency Medicine, University of Pittsburgh School of Medicine, 230 McKee Place, Suite 400, Pittsburgh, PA 15213, USA
Resuscitation 67:69-74. 2005.... - Inter-rater reliability for witnessed collapse and presence of bystander CPRJon C Rittenberger
Department of Emergency Medicine, University of Pittsburgh, 230 McKee Place, Suite 400, Pittsburgh, PA 15213, USA
Resuscitation 70:410-5. 2006..We sought to determine the inter-rater reliability for different methods of ascertaining and defining witnessed collapse and performance of bystander CPR... - Thrombin-antithrombin appearance in out-of-hospital cardiac arrestDavid Hostler
Department of Emergency Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
Prehosp Emerg Care 11:9-13. 2007..We characterized the prevalence of thrombogenesis during OOHCA by measuring plasma levels of thrombin-antithrombin complexes (TAT)... - Increased chest compression to ventilation ratio improves delivery of CPRDavid Hostler
University of Pittsburgh, Pittsburgh, United States
Resuscitation 74:446-52. 2007..We evaluated a protocol change from the recommended C:V ratio of 15:2-30:2 during CPR in our municipal emergency medical system... - Core temperature cooling in healthy volunteers after rapid intravenous infusion of cold and room temperature saline solutionTracy M Moore
Department of Emergency Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
Ann Emerg Med 51:153-9. 2008..9% saline solution during 30 minutes to healthy subjects (aged 27 [standard deviation (SD) 4] years) will reduce core body temperature to the therapeutic range of 33 degrees C to 35 degrees C (91.4 degrees F to 95 degrees F)... - Predictors of ROSC in witnessed aeromedical cardiac arrestsJon C Rittenberger
Department of Emergency Medicine, University of Pittsburgh, Pittsburgh, PA, United States
Resuscitation 76:43-6. 2008..We completed a retrospective analysis of aeromedical patient care records in order to describe the pre-arrest characteristics and the return of spontaneous circulation (ROSC) in this subset of patients... - Neurological and functional status following cardiac arrest: method and tool utilityKetki D Raina
University of Pittsburgh, School of Health and Rehabilitation Sciences, Department of Occupational Therapy, 5012 Forbes Tower, Pittsburgh, PA 15260, USA
Resuscitation 79:249-56. 2008..This study examined the relationships among the CPC and measures of global disability and QOL at discharge from the hospital and at 1 month after CA... - Rescue shock outcomes during out-of-hospital cardiac arrestBruce M Lo
Department of Emergency Medicine, University of Pittsburgh, Pittsburgh, PA, USA
Resuscitation 75:469-75. 2007..The purpose of this study is to describe rescue shock outcomes in a single system using a specific defibrillation protocol... - A mobile phone text message program to measure oral antibiotic use and provide feedback on adherence to patients discharged from the emergency departmentBrian Suffoletto
Department of Emergency Medicine, University of Pittsburgh, Pittsburgh, PA, USA
Acad Emerg Med 19:949-58. 2012..Nonadherence to prescribed medications impairs therapeutic benefits. The authors measured the ability of an automated text messaging (short message service [SMS]) system to improve adherence to postdischarge antibiotic prescriptions... - The availability and use of out-of-hospital physiologic information to identify high-risk injured children in a multisite, population-based cohortCraig D Newgard
Center for Policy and Research in Emergency Medicine, Department of Emergency Medicine, Oregon Health and Science University, Portland, Oregon 97239 3098, USA
Prehosp Emerg Care 13:420-31. 2009.... - A comparison of CPR delivery with various compression-to-ventilation ratios during two-rescuer CPRDavid Hostler
University of Pittsburgh, Department of Emergency Medicine and the Affiliated Emergency Medicine Residency, 230 McKee Place, Suite 500, Pittsburgh, PA 15213, USA
Resuscitation 65:325-8. 2005..We examined human performance of two-rescuer CPR using various C:V... - Cerebral oximetry in out-of-hospital cardiac arrest: standard CPR rarely provides detectable hemoglobin-oxygen saturation to the frontal cortexDavid H Newman
Department of Emergency Medicine, St Luke s Roosevelt Hospital, 1111 Amsterdam Avenue, New York, NY 10025, USA
Resuscitation 63:189-94. 2004..Ventilation rate does not alter the oximeter readings. It is possible that the current standard mechanical method of cardiopulmonary resuscitation provides little or no cerebral oxygenation during OOHCA... - Regional changes in glial cell line-derived neurotrophic factor after cardiac arrest and hypothermia in ratsKatherine M Schmidt
Department of Emergency Medicine, University of Pittsburgh, 230 McKee Place, Suite 400, Pittsburgh, PA 15213, USA
Neurosci Lett 368:135-9. 2004..These results suggest that temperature after resuscitation produces regionally specific changes of GNDF levels in brain... - Hypothermic reperfusion after cardiac arrest augments brain-derived neurotrophic factor activationBrian J D'Cruz
Department of Emergency Medicine, University of Pittsburgh, Pennsylvania 15213, USA
J Cereb Blood Flow Metab 22:843-51. 2002..Increased activation of BDNF signaling is a possible mechanism by which mild hypothermia is able to reduce the neuronal damage typically occurring after cardiac arrest... - Prevalence of troponin-T elevation during out-of-hospital cardiac arrestChristopher S Lai
Department of Emergency Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
Am J Cardiol 93:754-6. 2004..04 to 1.17). Elevated troponin levels did not reliably predict short-term outcome. Because troponin increases hours after the onset of ischemia, these data reveal that about 40% of OOHCA cases can undergo intervention before collapse... - Delayed hypothermia preferentially increases expression of brain-derived neurotrophic factor exon III in rat hippocampus after asphyxial cardiac arrestPeter S Vosler
Department of Emergency Medicine, University of Pittsburgh, 230 McKee Place, Suite 400, Pittsburgh, PA 15213, USA
Brain Res Mol Brain Res 135:21-9. 2005..These data suggest that hypothermia after cardiac arrest produces exon-specific changes in BDNF transcription... - Comparison of the effects of hypothermia at 33 degrees C or 35 degrees C after cardiac arrest in ratsEric S Logue
Department of Emergency Medicine, Safar Center for Resuscitation Research, University of Pittsburgh, Pittsburgh, PA, USA
Acad Emerg Med 14:293-300. 2007..Using a rat model, the authors tested the hypothesis that cooling to 35 degrees C between hours 1 and 24 after resuscitation would improve neurologic outcome as much as cooling to 33 degrees C... - Text-message-based drinking assessments and brief interventions for young adults discharged from the emergency departmentBrian Suffoletto
Department of Emergency Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
Alcohol Clin Exp Res 36:552-60. 2012..The feasibility of screening young adults in the ED, recruiting them for a TM-based interventional trial, collecting weekly drinking data through TM, and the variance in drinking outcomes remains unknown... - Work of CPR during two different compression to ventilation ratios with real-time feedbackAmy E Betz
Department of Emergency Medicine, University of Pittsburgh, Pittsburgh, PA 15213, United States
Resuscitation 79:278-82. 2008..The effect of the additional exertion required to deliver more chest compressions may present a considerable physical burden on the provider... - Coronary angiography predicts improved outcome following cardiac arrest: propensity-adjusted analysisJoshua C Reynolds
Department of Emergency Medicine, University of Maryland, Baltimore, Maryland, USA
J Intensive Care Med 24:179-86. 2009..Determine if clinical parameters of resuscitated patients predict coronary angiography (CATH) performance and if receiving CATH after cardiac arrest is associated with outcome... - Resuscitation Outcomes Consortium (ROC) PRIMED cardiac arrest trial methods part 1: rationale and methodology for the impedance threshold device (ITD) protocolTom P Aufderheide
Milwaukee, WI, USA
Resuscitation 78:179-85. 2008..Secondary aims are to compare functional status and depression at discharge and at 3 and 6 months post-discharge in survivors... - Overcoming ACLS dogma: how quickly should we change?James J Menegazzi
Prehosp Emerg Care 7:410-3. 2003..At the end of the year 2000 there was insufficient evidence to recommend any other approach than shock as soon as possible and perform CPR at all other times... - Regional variation in out-of-hospital cardiac arrest incidence and outcomeGraham Nichol
Department of Biostatistics, University of Washington Clinical Trial Center, Seattle, WA, USA
JAMA 300:1423-31. 2008..The health and policy implications of regional variation in incidence and outcome of out-of-hospital cardiac arrest remain to be determined... - Winning the cold war: inroads into implementation of mild hypothermia after cardiac arrest in adults from the European Resuscitation Council Hypothermia After Cardiac Arrest Registry Study GroupEricka L Fink
Crit Care Med 35:1199-202. 2007 - Adenosine A1 receptor antagonism hastens the decay in ventricular fibrillation waveform morphology during porcine cardiac arrestTimothy J Mader
The Department of Emergency Medicine, Baystate Medical Center Tufts University School of Medicine, 759 Chestnut Street, Springfield, MA 01199, United States
Resuscitation 71:254-9. 2006..The objective of this study was to determine the effect of ADO receptor antagonism, as measured by the scaling exponent (ScE), on the degeneration of VF over time during the circulatory phase of cardiac arrest... - The Resuscitation Outcomes Consortium Epistry-Trauma: design, development, and implementation of a North American epidemiologic prehospital trauma registryCraig D Newgard
Center for Policy and Research in Emergency Medicine, Department of Emergency Medicine, Oregon Health and Science University, Portland, OR 97239 3098, United States
Resuscitation 78:170-8. 2008..This data registry samples patients from 264 EMS agencies transporting to 287 acute care hospitals in both the United States and Canada... - Rationale, development and implementation of the Resuscitation Outcomes Consortium Epistry-Cardiac ArrestLaurie J Morrison
Prehospital and Transport Medicine Research Program, Sunnybrook and Women s College Health Sciences Centre, 2075 Bayview Avenue, Suite C753, Toronto, Ontario, Canada M4N 3M5
Resuscitation 78:161-9. 2008..To describe the development, design and consequent scientific implications of the Resuscitation Outcomes Consortium (ROC) population-based registry; ROC Epistry-Cardiac Arrest...
Research Grants
- BRAIN ISCHEMIA AND MAP KINASE ACTIVATIONClifton Callaway; Fiscal Year: 2003..The conduct of this project will provide extensive opportunities for collaboration with other basic scientists at the University of Pittsburgh, and promote the candidate's growth as an independent researcher. ..
- Hypothermia and Gene Expression After Cardiac ArrestClifton Callaway; Fiscal Year: 2005..These pathways will be blocked and stimulated during hypothermic reperfusion, and behavioral and histological outcome for cardiac arrest will be measured. ..
- Pittsburgh Resuscitation NetworkClifton Callaway; Fiscal Year: 2007..A clinical research training core is also described for purposes of training a young investigator within the Consortium. ..