Research Topics
Species | M B CallanSummaryAffiliation: University of Pennsylvania Country: USA Publications
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Detail Information
Publications
Canine platelet transfusionsMary Beth Callan
Department of Pathology and Laboratory Medicine, School of Medicine, University of Pennsylvania, Philadelphia, PA 19104 6010, USA
J Vet Emerg Crit Care (San Antonio) 19:401-15. 2009..To review potential platelet storage options, guidelines for administration of platelets, and adverse events associated with platelet transfusions...
Clinical and clinicopathologic effects of plateletpheresis on healthy donor dogsMary Beth Callan
Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104 6010, USA
Transfusion 48:2214-21. 2008..The safety and feasibility of plateletpheresis using a commercially available apheresis system (COBE Spectra, Gambro BCT) were evaluated in donor dogs, with characterization of its clinical and clinicopathologic effects...
Multiple papillomavirus-associated epidermal hamartomas and squamous cell carcinomas in situ in a dog following chronic treatment with prednisone and cyclosporineMary Beth Callan
Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104 6010, USA
Vet Dermatol 16:338-45. 2005..This is the first reported case of papillomavirus-associated squamous cell carcinoma in situ developing in a dog following chronic administration of cyclosporine and prednisone...
Chrono-lume and magnesium potentiate aggregation of canine but not human platelets in citrated platelet-rich plasmaM B Callan
Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia 19104 6010, USA
Thromb Haemost 80:176-80. 1998..Platelet aggregation studies of animals with suspected thrombopathias should be performed without CL to prevent masking of a platelet function defect...
Inherited platelet delta-storage pool disease in dogs causing severe bleeding: an animal model for a specific ADP deficiencyM B Callan
Department of Clinical Studies, University of Pennsylvania School of Veterinary Medicine, Philadelphia 19104 6010, USA
Thromb Haemost 74:949-53. 1995..Additional studies of this unique platelet disorder will provide an opportunity to understand the mechanism of adenine nucleotide storage in platelet delta-granules...
Thrombopathies causing bleeding in a boxer and mixed-breed dogM B Callan
Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia 19104-6010, USA
J Am Anim Hosp Assoc 37:244-50. 2001..1 demonstrated the presence of glycoprotein IIb/IIIa and Ib receptors. Thus, the intrinsic platelet function defects may be different in these two dogs and may likely represent secretion/signal transduction disorders...
Use of a hemoglobin-based oxygen-carrying solution in cats: 72 cases (1998-2000)Gillian R Gibson
Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia 19104-6010, USA
J Am Vet Med Assoc 221:96-102. 2002....
Clinical application of a hemoglobin-based oxygen-carrying solutionMary Beth Callan
Ryan Veterinary Hospital of the University of Pennsylvania, School of Veterinary Medicine, Philadelphia, 3900 Delancey Street, Philadelphia, PA 19104 6010, USA
Vet Clin North Am Small Anim Pract 33:1277-93, vi. 2003..Measurement of total or plasma hemoglobin concentration can be used as an aid in monitoring patients receiving Oxyglobin...
Assessment of a point-of-care instrument for identification of primary hemostatic disorders in dogsM B Callan
Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia 19104-6010, USA
Am J Vet Res 62:652-8. 2001..Use of this instrument may be helpful for making decisions regarding management of dogs with primary hemostatic disorders...
Cryopreservation of canine plateletsE H Appleman
Schools of Veterinary Medicine and Medicine, University of Pennsylvania, Philadelphia, PA, USA
J Vet Intern Med 23:138-45. 2009..Platelet cryopreservation allows long-term storage and immediate availability of transfusion products...
Clinical indications for use of fresh frozen plasma in dogs: 74 dogs (October through December 1999)J C Logan
Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia 19104-6010, USA
J Am Vet Med Assoc 218:1449-55. 2001..Because the supply of FFP is limited, guidelines for when administration of FFP may be clinically useful should be developed...
Comparison of platelet count recovery with use of vincristine and prednisone or prednisone alone for treatment for severe immune-mediated thrombocytopenia in dogsElizabeth A Rozanski
Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia 19104-6010, USA
J Am Vet Med Assoc 220:477-81. 2002..Early use of vincristine seems warranted in dogs with severe primary IMT...
A novel missense mutation responsible for factor VII deficiency in research Beagle coloniesM B Callan
School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA
J Thromb Haemost 4:2616-22. 2006..Canine factor VII (cFVII) deficiency, an autosomal recessive trait originally identified in research Beagles, is associated with a mild to moderate bleeding tendency...
Congenital esophageal hiatal hernia in the Chinese shar-pei dogM B Callan
Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia 19104 6010
J Vet Intern Med 7:210-5. 1993..Eight of the animals survived surgery, six of which have been asymptomatic since surgery (19 to 36 months). The megaesophagus, esophageal hypomotility, and bronchopneumonia resolved in all of these dogs...
Effect of desmopressin on von Willebrand factor multimers in Doberman Pinschers with type 1 von Willebrand diseaseMary Beth Callan
Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
Am J Vet Res 66:861-7. 2005..CONCLUSIONS AND CLINICAL RELEVANCE: Beneficial effects of DDAVP on primary hemostasis in Doberman Pinschers with type 1 vWD cannot be explained by preferential increases in HMW vWF multimers...
Hereditary factor VII deficiency in the Alaskan Klee Kai dogJennifer A Kaae
Department of Medical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI, USA
J Vet Intern Med 21:976-81. 2007..An Alaskan Klee Kai dog with severe bleeding after trauma was diagnosed with FVII deficiency based on coagulation testing. Molecular analyses were undertaken to identify the genetic basis of the defect in this breed...
Effect of desmopressin acetate administration on primary hemostasis in Doberman Pinschers with type-1 von Willebrand disease as assessed by a point-of-care instrumentMary Beth Callan
Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
Am J Vet Res 63:1700-6. 2002....
Effects of anticoagulant on pH, ionized calcium concentration, and agonist-induced platelet aggregation in canine platelet-rich plasmaMary Beth Callan
Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
Am J Vet Res 70:472-7. 2009..Choice of anticoagulant may influence results of in vitro evaluation of platelet function, which can lead to erroneous conclusions...
Evaluation of a canine D-dimer point-of-care test kit for use in samples obtained from dogs with disseminated intravascular coagulation, thromboembolic disease, and hemorrhageAlison Griffin
Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
Am J Vet Res 64:1562-9. 2003..CONCLUSIONS AND CLINICAL RELEVANCE: The cD-d POC test kit can be quickly and easily used and reliably detects dogs with DIC or acute TED. Positive results may also be seen in dogs with internal hemorrhage...
Changes in platelet function, hemostasis, and prostaglandin expression after treatment with nonsteroidal anti-inflammatory drugs with various cyclooxygenase selectivities in dogsBenjamin M Brainard
Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens GA 30602, USA
Am J Vet Res 68:251-7. 2007..To determine the effects of nonsteroidal anti-inflammatory drugs of various cyclooxygenase selectivities on hemostasis and prostaglandin expression in dogs...
