Research Topics
| M R CaligiuriSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
Nonadherence to the isochrony principle in forged signaturesMichael P Caligiuri
University of California, San Diego, La Jolla, CA, United States Electronic address
Forensic Sci Int 223:228-32. 2012..These findings suggest that when forging signatures, writers execute pen movements having steeper duration-amplitude relationships than for genuine signatures...
Association of diabetes with dyskinesia in older psychosis patientsMichael P Caligiuri
Department of Psychiatry 0603, School of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA
Psychopharmacology (Berl) 176:281-6. 2004..Advanced age is also an important risk factor for diabetes, which may be associated with TD. These observations suggest that older diabetic patients may be particularly vulnerable to developing TD...- A portable hand-held device for quantifying and standardizing tremor assessmentM P Caligiuri
Department of Psychiatry, University of California, San Diego, CA, USA
J Med Eng Technol 28:254-62. 2004..The portability of this instrument, referred to as the Tremorometer, makes it a useful tool for multi-site collaborative studies in community settings... - Do preclinical findings of methamphetamine-induced motor abnormalities translate to an observable clinical phenotype?Michael P Caligiuri
UCSD School of Medicine, Department of Psychiatry and Psychiatry Service, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA
Neuropsychopharmacology 30:2125-34. 2005..Significant differences in the expression of neurotoxicity and presence of multiple environmental and pharmacologic confounds may account for the lack of a parkinsonian phenotype in humans despite evidence of altered dopamine function... - Lateralized cognitive dysfunction and psychotic symptoms in schizophreniaMichael P Caligiuri
University of California, San Diego, San Diego, CA, USA
Schizophr Res 80:151-61. 2005.... - Striatopallidal regulation of affect in bipolar disorderMichael P Caligiuri
Department of Psychiatry, University of California at San Diego, USA
J Affect Disord 91:235-42. 2006..The aim of this study was to increase our understanding of the functional role of the basal ganglia and thalamus in relation to change in affect in patients with bipolar disorder... - Quantitative measurement of handwriting in the assessment of drug-induced parkinsonismMichael P Caligiuri
University of California, Department of Psychiatry, 9500 Gilman Drive, La Jolla, CA 29093, USA
Hum Mov Sci 25:510-22. 2006..This study demonstrates that kinematic analyses of pen movements during handwriting may be useful in detecting and monitoring subtle changes in motor control related to the adverse effects of psychotropic medications... 
Handwriting movement analyses for monitoring drug-induced motor side effects in schizophrenia patients treated with risperidoneMichael P Caligiuri
Department of Psychiatry 0603, University of California, La Jolla, CA 92093, USA
Hum Mov Sci 28:633-42. 2009..In contrast, we found no association between observer-based EPS severity ratings and medication dose. These findings support the importance of handwriting-based measures to monitor EPS in medicated schizophrenia patients...- Handwriting movement kinematics for quantifying extrapyramidal side effects in patients treated with atypical antipsychoticsMichael P Caligiuri
Department of Psychiatry, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA
Psychiatry Res 177:77-83. 2010..These findings support the ecological validity of handwriting movement analysis as an objective behavioral biomarker for quantifying the effects of antipsychotic medication and dose on the motor system... - A quantitative neuromotor predictor of antidepressant non-response in patients with major depressionMichael P Caligiuri
Department of Psychiatry, University of California, San Diego and Psychiatry Services of the VA San Diego Healthcare System, San Diego, CA, USA
J Affect Disord 77:135-41. 2003..These results demonstrate that a quantitative measure of motor programming may be a useful predictor of antidepressant non-response... - Neuromotor abnormalities and risk for psychosis in Alzheimer's diseaseM P Caligiuri
Department of Psychiatry, University of California, San Diego, and the UCSD Alzheimer s Disease Research Center, La Jolla, CA 92093, USA
Neurology 61:954-8. 2003.... - An fMRI study of affective state and medication on cortical and subcortical brain regions during motor performance in bipolar disorderMichael P Caligiuri
Movement Disorders Laboratory, Department of Psychiatry 0603, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA
Psychiatry Res 123:171-82. 2003.... - Extrapyramidal side effects in patients with Alzheimer's disease treated with low-dose neuroleptic medicationM P Caligiuri
Department of Psychiatry, University of California, San Diego, USA
Am J Geriatr Psychiatry 6:75-82. 1998..These findings suggest that a substantial proportion of AD patients treated with neuroleptics develop significant EPS and that the risk for EPS can be estimated before intervention by use of instruments measuring motor function... - Scaling of movement velocity: a measure of neuromotor retardation in individuals with psychopathologyM P Caligiuri
Department of Psychiatry, University of California at San Diego, La Jolla 92058, USA
Psychophysiology 35:431-7. 1998..We conclude that this measure of velocity scaling is relatively uninfluenced by cognitive factors that may underlie psychomotor retardation... - Incidence and predictors of drug-induced parkinsonism in older psychiatric patients treated with very low doses of neurolepticsM P Caligiuri
Department of Psychiatry, University of California, San Diego, La Jolla 92053, USA
J Clin Psychopharmacol 19:322-8. 1999.... - An instrumental study of the relationship between extrapyramidal signs and psychosis in Alzheimer's diseaseM P Caligiuri
Department of Psychiatry, University of California, San Diego, La Jolla 92053, USA
J Neuropsychiatry Clin Neurosci 12:34-9. 2000..The association between parkinsonism and delusions and hallucinations suggests a subcortical mechanism in the etiopathology of psychosis in AD... - Motor and cognitive aspects of motor retardation in depressionM P Caligiuri
Department of Psychiatry 0603, Movement Disorders Laboratory, University of California at San Diego, La Jolla, CA 92093, USA
J Affect Disord 57:83-93. 2000..However, overt presentations of motor slowing cannot distinguish slowness due to cognitive factors from slowness due to neuromotor disturbances... - Antipsychotic-Induced movement disorders in the elderly: epidemiology and treatment recommendationsM R Caligiuri
Department of Psychiatry, University of California, San Diego, La Jolla, California 92093, USA
Drugs Aging 17:363-84. 2000..At the present time, there is no consistently effective treatment for patients with TD once it develops. Therefore, attention should focus on its prevention and close monitoring... - Instrumental motor predictors of neuroleptic-induced parkinsonism in newly medicated schizophrenia patientsM P Caligiuri
Department of Psychiatry, School of Medicine, University of California, San Diego, La Jolla 92053, USA
J Neuropsychiatry Clin Neurosci 9:562-7. 1997..These findings suggest that pretreatment motor dysfunction may be a risk factor for drug-induced parkinsonism, especially among older patients... - Extrapyramidal signs and cognitive abilities in Alzheimer's diseaseM P Caligiuri
Department of Psychiatry, University of California, San Diego 92093, USA
Int J Geriatr Psychiatry 16:907-11. 2001..To evaluate whether the relationship between extrapyramidal signs (EPS) and cognitive disturbances in Alzheimer's disease (AD) is influenced by illness duration... - Treatment predictors of extrapyramidal side effects in patients with tardive dyskinesia: results from Veterans Affairs Cooperative Study 394James B Lohr
Psychiatry Service, San Diego Department of Veterans Affairs Medical Center, California 92161, USA
J Clin Psychopharmacol 22:196-200. 2002..These findings indicate that clinician-modifiable factors related to medication usage can influence the outcome of TD and EPS in patients with persistent TD... - A functional magnetic resonance imaging study of cortical asymmetry in bipolar disorderMichael P Caligiuri
Department of Psychiatry, University of California at San Diego, and VISN 22 Mental Illness Research, Education, and Clinical Center, VA San Diego Healthcare System, USA
Bipolar Disord 6:183-96. 2004..A secondary goal of the study was to examine effects of psychotropic medications on blood volume changes in the motor cortices... - Abnormalities in motor physiology in bipolar disorderJames B Lohr
Department of Psychiatry, University of California, San Diego, CA, USA
J Neuropsychiatry Clin Neurosci 18:342-9. 2006..This study demonstrates that motor abnormalities suggestive of basal ganglia dysfunction occur in many patients with bipolar disorder... - Internal versus external: oral-motor performance as a function of attentional focusSkott E Freedman
SDSU UCSD Joint Doctoral Program in Language and Communicative Disorders, San Diego State University, 5500 Campanile Drive, San Diego, CA 92182 1518, USA
J Speech Lang Hear Res 50:131-6. 2007..This study tested the hypothesis that the effects of attentional focus on limb performance would also occur in the oral-facial system... - Impaired hemispheric communication in schizophrenia: a study using the consonant-vowel-consonant taskJames B Lohr
Department of Psychiatry, San Diego VA Healthcare System, University of California at San Diego, USA
Schizophr Res 87:279-88. 2006.... - Reduction in neuroleptic-induced movement disorders after a switch to quetiapine in patients with schizophreniaLeonardo Cortese
The University of Western Ontario, Windsor, Ontario, Canada
J Clin Psychopharmacol 28:69-73. 2008..We designed the present study to examine whether patients with preexisting EPS switched to quetiapine would show greater reduction in EPS compared with control patients... - Predictors of neuroleptic-induced dyskinesia and parkinsonism: the influence of measurement methods and definitionsCharles E Dean
Psychiatric Movement Disorders Clinic, Minneapolis Veterans Affairs Medical Center, MN 55417, USA
J Clin Psychopharmacol 26:560-5. 2006..Increasing age and a lower score on the MMSE seem to be particularly helpful in gauging the risk for parkinsonian and dyskinetic movements... - Relationship of neuromotor disturbances to psychosis symptoms in first-episode neuroleptic-naive schizophrenia patientsLeonardo Cortese
The University of Western Ontario and Windsor Regional Hospital, Windsor Ontario, Canada
Schizophr Res 75:65-75. 2005.... - Clinical rating scales and instruments: how do they compare in assessing abnormal, involuntary movements?Charles E Dean
Tardive Dyskinesia Assessment Clinic, Minneapolis VA Medical Center, MH PSL, 116A, Minneapolis, MN 55417, USA
J Clin Psychopharmacol 24:298-304. 2004..We also hypothesized that the DISCUS, by virtue of its more detailed protocol, would be more sensitive than the AIMS... - PhenoChipping of psychotic disorders: a novel approach for deconstructing and quantitating psychiatric phenotypesAlexander B Niculescu
Laboratory of Neurophenomics, Institute of Psychiatric Research, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
Am J Med Genet B Neuropsychiatr Genet 141:653-62. 2006..Empirically derived clusterings of (endo)phenotypes and of patients will better serve genetic, pharmacological, and imaging research, as well as clinical practice...