Vince Calhoun

Summary

Affiliation: University of New Mexico
Country: USA

Publications

  1. pmc Exploring the psychosis functional connectome: aberrant intrinsic networks in schizophrenia and bipolar disorder
    Vince D Calhoun
    The Mind Research Network Albuquerque, NM, USA
    Front Psychiatry 2:75. 2011
  2. pmc Altered small-world brain networks in schizophrenia patients during working memory performance
    Hao He
    The MIND Research Network, Albuquerque, New Mexico, United States of America
    PLoS ONE 7:e38195. 2012
  3. pmc Functional brain networks in schizophrenia: a review
    Vince D Calhoun
    The Mind Research Network Albuquerque, NM, USA
    Front Hum Neurosci 3:17. 2009
  4. pmc Structural angle and power images reveal interrelated gray and white matter abnormalities in schizophrenia
    Lai Xu
    The MIND Research Network, Albuquerque, NM 87106, USA
    Neurol Res Int 2012:735249. 2012
  5. pmc COINS: An Innovative Informatics and Neuroimaging Tool Suite Built for Large Heterogeneous Datasets
    Adam Scott
    The Mind Research Network Albuquerque, NM, USA
    Front Neuroinform 5:33. 2011
  6. pmc Independent component analysis for brain FMRI does indeed select for maximal independence
    Vince D Calhoun
    Medical Image Analysis Lab, The MIND Research Network, Albuquerque, New Mexico, USA
    PLoS ONE 8:e73309. 2013
  7. pmc Group sparse canonical correlation analysis for genomic data integration
    Dongdong Lin
    Biomedical Engineering Department, Tulane University, New Orleans, LA, USA
    BMC Bioinformatics 14:245. 2013
  8. doi request reprint Multisubject independent component analysis of fMRI: a decade of intrinsic networks, default mode, and neurodiagnostic discovery
    Vince D Calhoun
    MIND Research Network, Albuquerque, NM 87106, USA
    IEEE Rev Biomed Eng 5:60-73. 2012
  9. pmc Decomposing the brain: components and modes, networks and nodes
    Vince D Calhoun
    The MIND Research Network, Albuquerque, New Mexico 87106, USA
    Trends Cogn Sci 16:255-6. 2012
  10. pmc Temporal lobe and "default" hemodynamic brain modes discriminate between schizophrenia and bipolar disorder
    Vince D Calhoun
    Olin Neuropsychiatry Research Center, Institute of Living, Hartford, Connecticut, USA
    Hum Brain Mapp 29:1265-75. 2008

Detail Information

Publications88

  1. pmc Exploring the psychosis functional connectome: aberrant intrinsic networks in schizophrenia and bipolar disorder
    Vince D Calhoun
    The Mind Research Network Albuquerque, NM, USA
    Front Psychiatry 2:75. 2011
    ..Patients exhibited similar frequency behavior across multiple networks with decreased low frequency power. In summary, a comprehensive analysis of INs reveals a key role for the default mode in both schizophrenia and bipolar disorder...
  2. pmc Altered small-world brain networks in schizophrenia patients during working memory performance
    Hao He
    The MIND Research Network, Albuquerque, New Mexico, United States of America
    PLoS ONE 7:e38195. 2012
    ..SZ show distinctly inefficient and variable network structures in response to WM load increase, comparing to stable highly clustered network topologies in HC...
  3. pmc Functional brain networks in schizophrenia: a review
    Vince D Calhoun
    The Mind Research Network Albuquerque, NM, USA
    Front Hum Neurosci 3:17. 2009
    ..In summary, it is clear that identification of brain networks and their inter-relationships with fMRI has great potential to improve our understanding of schizophrenia...
  4. pmc Structural angle and power images reveal interrelated gray and white matter abnormalities in schizophrenia
    Lai Xu
    The MIND Research Network, Albuquerque, NM 87106, USA
    Neurol Res Int 2012:735249. 2012
    ..Our approach has wide applicability for studying tissue distribution differences in the healthy and diseased brain...
  5. pmc COINS: An Innovative Informatics and Neuroimaging Tool Suite Built for Large Heterogeneous Datasets
    Adam Scott
    The Mind Research Network Albuquerque, NM, USA
    Front Neuroinform 5:33. 2011
    ....
  6. pmc Independent component analysis for brain FMRI does indeed select for maximal independence
    Vince D Calhoun
    Medical Image Analysis Lab, The MIND Research Network, Albuquerque, New Mexico, USA
    PLoS ONE 8:e73309. 2013
    ..We show that these experiments fall short of proving this claim and that the ICA algorithms are indeed doing what they are designed to do: identify maximally independent sources. ..
  7. pmc Group sparse canonical correlation analysis for genomic data integration
    Dongdong Lin
    Biomedical Engineering Department, Tulane University, New Orleans, LA, USA
    BMC Bioinformatics 14:245. 2013
    ..However, they overlook the structural or group effect within genomic data in the analysis, which often exist and are important (e.g., SNPs spanning a gene interact and work together as a group)...
  8. doi request reprint Multisubject independent component analysis of fMRI: a decade of intrinsic networks, default mode, and neurodiagnostic discovery
    Vince D Calhoun
    MIND Research Network, Albuquerque, NM 87106, USA
    IEEE Rev Biomed Eng 5:60-73. 2012
    ..In summary, we are in exciting times and still just beginning to reap the benefits of the richness of functional brain networks as well as available analytic approaches...
  9. pmc Decomposing the brain: components and modes, networks and nodes
    Vince D Calhoun
    The MIND Research Network, Albuquerque, New Mexico 87106, USA
    Trends Cogn Sci 16:255-6. 2012
    ..Compared to the widely used spatial ICA (sICA), tICA better allows for a brain region to engage in multiple, independent interactions with other regions and will potentially offer new insights into brain function...
  10. pmc Temporal lobe and "default" hemodynamic brain modes discriminate between schizophrenia and bipolar disorder
    Vince D Calhoun
    Olin Neuropsychiatry Research Center, Institute of Living, Hartford, Connecticut, USA
    Hum Brain Mapp 29:1265-75. 2008
    ..A combination of two such hemodynamic brain networks shows promise as a biomarker for schizophrenia and bipolar disorder...
  11. pmc A selective review of simulated driving studies: Combining naturalistic and hybrid paradigms, analysis approaches, and future directions
    V D Calhoun
    The MIND Research Network, Albuquerque, NM 87106, USA
    Neuroimage 59:25-35. 2012
    ..Overall, the use of hybrid driving studies is a particularly promising area of neuroscience investigation...
  12. pmc A review of group ICA for fMRI data and ICA for joint inference of imaging, genetic, and ERP data
    Vince D Calhoun
    The MIND Research Network, Albuquerque, NM 87131, USA
    Neuroimage 45:S163-72. 2009
    ..As demonstrated by a number of examples in this paper, ICA is a powerful and versatile data-driven approach for studying the brain...
  13. pmc Feature-based fusion of medical imaging data
    Vince D Calhoun
    Mind Research Network and Department of Electrical and Computer Engineering, University of New Mexico, Albuquerque, NM 87131, USA
    IEEE Trans Inf Technol Biomed 13:711-20. 2009
    ..We also propose a method for selecting which combination of modalities provides the greatest value in discriminating groups. Finally, we summarize and describe future research topics...
  14. pmc Modulation of temporally coherent brain networks estimated using ICA at rest and during cognitive tasks
    Vince D Calhoun
    Olin Neuropsychiatry Research Center, Institute of Living, Hartford, Connecticut 06106, USA
    Hum Brain Mapp 29:828-38. 2008
    ..In summary, TCNs show considerable promise as potential imaging biological markers of brain diseases, though each network needs to be studied in more detail...
  15. pmc Effect of surrounding vasculature on intravoxel BOLD signal
    Zikuan Chen
    The MIND Research Network, Albuquerque, New Mexico 87106, USA
    Med Phys 37:1778-87. 2010
    ..In this article, the authors study the effect of the surrounding vasculature on the magnetic field and the BOLD signal at a cortical voxel by numerical simulation...
  16. pmc Diffusion tensor imaging in schizophrenia: relationship to symptoms
    Laurie R Skelly
    Olin Neuropsychiatry Research Center, Institute of Living, Hartford, CT 06106, USA
    Schizophr Res 98:157-62. 2008
    ....
  17. pmc Combining fMRI and SNP data to investigate connections between brain function and genetics using parallel ICA
    Jingyu Liu
    The MIND Research Network, Albuquerque, New Mexico, USA
    Hum Brain Mapp 30:241-55. 2009
    ....
  18. ncbi request reprint Unmixing fMRI with independent component analysis
    Vince D Calhoun
    Medical Image Analysis Lab, Olin Neuropsychiatry Research Center, Hartford, CT 06106, USA
    IEEE Eng Med Biol Mag 25:79-90. 2006
  19. pmc Dysregulation of working memory and default-mode networks in schizophrenia using independent component analysis, an fBIRN and MCIC study
    Dae Il Kim
    The MIND Research Network, Albuquerque, New Mexico 87131, USA
    Hum Brain Mapp 30:3795-811. 2009
    ....
  20. doi request reprint Parallel independent component analysis using an optimized neurovascular coupling for concurrent EEG-fMRI sources
    Lei Wu
    Mind Research Network and Electrical and Computer Engineering Department, University of New Mexico, Albuquerque, NM 87106, USA
    Conf Proc IEEE Eng Med Biol Soc 2011:2542-5. 2011
    ..The results from our simulations yield an accurate source tracking and linkage for concurrent EEG-fMRI, and provide a novel and efficient way to combine EEG and hemodynamic responses...
  21. doi request reprint Computed inverse resonance imaging for magnetic susceptibility map reconstruction
    Zikuan Chen
    The MIND Research Network, University of New Mexico, Albuquerque, NM 87106, USA
    J Comput Assist Tomogr 36:265-74. 2012
    ..This article reports a computed inverse magnetic resonance imaging (CIMRI) model for reconstructing the magnetic susceptibility source from MRI data using a 2-step computational approach...
  22. pmc A computational multiresolution BOLD fMRI model
    Zikuan Chen
    MIND Research Network, Albuquerque, NM 87106, USA
    IEEE Trans Biomed Eng 58:2995-9. 2011
    ..Under a small-angle approximation, we find that the BOLD signal intensity is related to its phase counterpart (or BOLD fieldmap) across two spatial resolution levels...
  23. pmc A method for functional network connectivity among spatially independent resting-state components in schizophrenia
    Madiha J Jafri
    Olin Neuropsychiatry Research Center, Institute of Living, Hartford, CT 06106, USA
    Neuroimage 39:1666-81. 2008
    ..Significant differences between patient and control connectivity in different networks were revealed possibly reflecting deficiencies in cortical processing in patients...
  24. pmc Functional neural networks underlying response inhibition in adolescents and adults
    Michael C Stevens
    Olin Neuropsychiatry Research Center, Hartford, CT 06106, United
    Behav Brain Res 181:12-22. 2007
    ..We identify and characterize several age-related differences in the function of neural circuits that are associated with behavioral performance changes across adolescent development...
  25. pmc Investigation of relationships between fMRI brain networks in the spectral domain using ICA and Granger causality reveals distinct differences between schizophrenia patients and healthy controls
    Oguz Demirci
    The MIND Research Network, Albuquerque, NM 87131, USA
    Neuroimage 46:419-31. 2009
    ..Secondary visual and temporal lobe activations replaced these components during the AOD task...
  26. pmc A method for accurate group difference detection by constraining the mixing coefficients in an ICA framework
    Jing Sui
    The MIND Research Network, Albuquerque, New Mexico 87106, USA
    Hum Brain Mapp 30:2953-70. 2009
    ..The proposed algorithm performs quite well for both group-difference detection and multitask fMRI data fusion, which may prove especially important for the identification of relevant disease biomarkers...
  27. pmc Changes in fMRI magnitude data and phase data observed in block-design and event-related tasks
    Sunil Kumar Arja
    The MIND Research Network, Albuquerque, NM 87131, USA
    Neuroimage 49:3149-60. 2010
    ..In addition, the phase can potentially increase sensitivity within regions also showing magnitude changes. Future work should focus on additional methods for combining the magnitude and phase data...
  28. pmc Rare copy number deletions predict individual variation in intelligence
    Ronald A Yeo
    Department of Psychology, University of New Mexico, Albuquerque, New Mexico, United States of America
    PLoS ONE 6:e16339. 2011
    ..Significant limitations of this research, including issues of generalizability and CNV measurement, are discussed...
  29. pmc A method for multitask fMRI data fusion applied to schizophrenia
    Vince D Calhoun
    Olin Neuropsychiatry Research Center, Institute of Living, Hartford, Connecticut 06106, USA
    Hum Brain Mapp 27:598-610. 2006
    ..It thus provides a way to integrate and probe brain networks using a variety of tasks and may increase our understanding of coordinated brain networks and the impact of pathology upon them...
  30. ncbi request reprint Aberrant "default mode" functional connectivity in schizophrenia
    Abigail G Garrity
    Trinity College, Hartford, CT, USA
    Am J Psychiatry 164:450-7. 2007
    ..It was hypothesized that the default mode network would show abnormal activation and connectivity in patients with schizophrenia...
  31. pmc Decreased default mode neural modulation with age in schizophrenia
    Christopher C Abbott
    Department of Psychiatry, University of New Mexico, Albuquerque, 87131 0001, USA
    Am J Geriatr Psychiatry 18:897-907. 2010
    ..The relationship between network modulation and age has not been assessed in patients with a long duration of illness...
  32. ncbi request reprint Functional neural circuits for mental timekeeping
    Michael C Stevens
    Olin Neuropsychiatry Research Center, Hartford, Connecticut 06106, USA
    Hum Brain Mapp 28:394-408. 2007
    ..These findings are discussed within the context of current biological and information processing models of neural timekeeping...
  33. ncbi request reprint Interparticipant correlations: a model free FMRI analysis technique
    Martin P Hejnar
    Olin Neuropsychiatry Research Center, Institute of Living, Hartford, Connecticut 06106, USA
    Hum Brain Mapp 28:860-7. 2007
    ..This technique, designed to have increased sensitivity to inter-subject correlations that are not necessarily task-related, may potentially be useful as a compliment to model-based approaches...
  34. doi request reprint Blood oxygenation level-dependent functional MRI signal turbulence caused by ultrahigh spatial resolution: numerical simulation and theoretical explanation
    Zikuan Chen
    The Mind Research Network and LEBRI, Albuquerque, NM 87106, USA
    NMR Biomed 26:248-64. 2013
    ..Overall, the main causes of voxel signal turbulence include a high spatial resolution, high field, long TE and large vessel...
  35. ncbi request reprint An adaptive reflexive processing model of neurocognitive function: supporting evidence from a large scale (n = 100) fMRI study of an auditory oddball task
    Kent A Kiehl
    Olin Neuropsychiatry Research Center, The Institute of Living, Hartford, CT 06106, USA
    Neuroimage 25:899-915. 2005
    ..This process may be termed 'adaptive reflexive processing.' The implications of these results for interpreting functional MRI studies are discussed...
  36. pmc Alcohol dose effects on brain circuits during simulated driving: an fMRI study
    Shashwath A Meda
    Olin Neuropsychiatry Research Center, Institute of Living at Hartford Hospital, Connecticut, USA
    Hum Brain Mapp 30:1257-70. 2009
    ..Overall, results suggest that alcohol (especially at high doses) causes significant impairment of both driving behavior and brain functionality related to motor planning and control, goal directedness, error monitoring, and memory...
  37. pmc Aberrant localization of synchronous hemodynamic activity in auditory cortex reliably characterizes schizophrenia
    Vince D Calhoun
    Institute of Living, Olin Neuropsychiatry Research Center, 200 Retreat Avenue, Hartford, CT 06106, USA
    Biol Psychiatry 55:842-9. 2004
    ..In this study, we attempted to examine auditory cortex function using an intrinsic, task-uncorrelated measure...
  38. pmc A projection pursuit algorithm to classify individuals using fMRI data: Application to schizophrenia
    Oguz Demirci
    The MIND Research Network, Albuquerque, NM 87106, USA
    Neuroimage 39:1774-82. 2008
    ..The findings suggest that the proposed data reduction algorithm is effective in classifying individuals into schizophrenia and healthy control groups and may eventually prove useful as a diagnostic tool...
  39. pmc Evidence for anomalous network connectivity during working memory encoding in schizophrenia: an ICA based analysis
    Shashwath A Meda
    Olin Neuropsychiatry Research Center, Institute of Living at Hartford Hospital, Hartford, Connecticut, United States of America
    PLoS ONE 4:e7911. 2009
    ..Numerous neuroimaging studies report abnormal regional brain activity during working memory performance in schizophrenia, but few have examined brain network integration as determined by "functional connectivity" analyses...
  40. pmc Resting state and task-induced deactivation: A methodological comparison in patients with schizophrenia and healthy controls
    Maggie V Mannell
    The MIND Research Network, Albuquerque, New Mexico, USA
    Hum Brain Mapp 31:424-37. 2010
    ..The increased posterior and reduced anterior connectivity may partially explain some of the cognitive dysfunction and clinical symptoms that are frequently associated with schizophrenia...
  41. pmc Reactivity of hemodynamic responses and functional connectivity to different states of alpha synchrony: a concurrent EEG-fMRI study
    Lei Wu
    The MIND Research Network, Albuquerque, New Mexico 87131, USA
    Neuroimage 52:1252-60. 2010
    ..e. low frequency hemodynamic signals display an equivalent of alpha reactivity...
  42. pmc A CCA+ICA based model for multi-task brain imaging data fusion and its application to schizophrenia
    Jing Sui
    The MIND Research Network, 1101 Yale Blvd, NE, Albuquerque, NM 87106, USA
    Neuroimage 51:123-34. 2010
    ..Such an approach fills a gap in existing multivariate methods for identifying biomarkers from brain imaging data...
  43. pmc Brain network dynamics during error commission
    Michael C Stevens
    Olin Neuropsychiatry Research Center, The Institute of Living Hartford Hospital, Hartford, Connecticut 06106, USA
    Hum Brain Mapp 30:24-37. 2009
    ..These findings characterize the spatial structure of neural networks underlying error commission and identify neurobiological differences between adolescents and adults...
  44. pmc Source-based morphometry: the use of independent component analysis to identify gray matter differences with application to schizophrenia
    Lai Xu
    MIND Institute, Albuquerque, New Mexico 87131, USA
    Hum Brain Mapp 30:711-24. 2009
    ..The SBM approach found changes not identified by VBM in basal ganglia, parietal, and occipital lobe. These findings show that SBM is a multivariate alternative to VBM, with wide applicability to studying changes in brain structure...
  45. pmc Temporal sequence of hemispheric network activation during semantic processing: a functional network connectivity analysis
    Michal Assaf
    Olin Neuropsychiatry Research Center, Institute of Living, Hartford Hospital, Hartford, CT, United States
    Brain Cogn 70:238-46. 2009
    ..poorer performers of the SORT. These results indicate an early activation of the RH that is closely followed by activation of the LH, to facilitate performance during word retrieval from SM...
  46. pmc Compensating the intensity fall-off effect in cone-beam tomography by an empirical weight formula
    Zikuan Chen
    The MIND Research Network, Albuquerque, New Mexico 87131, USA
    Appl Opt 47:6033-9. 2008
    ..Computer simulations and phantom experiments are presented to demonstrate the compensation effectiveness of the fall-off effect inherent in circular cone-beam tomography...
  47. doi request reprint An ICA-based method for the identification of optimal FMRI features and components using combined group-discriminative techniques
    Jing Sui
    The MIND Research Network, 1101 Yale Blvd, NE, Albuquerque, NM 87106, USA
    Neuroimage 46:73-86. 2009
    ..The proposed framework provides a general approach for selecting optimal brain networks which may serve as potential biomarkers of several brain diseases and thus has wide applicability in the neuroimaging research community...
  48. pmc Age-related cognitive gains are mediated by the effects of white matter development on brain network integration
    Michael C Stevens
    Olin Neuropsychiatry Research Center, Whitehall Building, The Institute of Living Hartford Hospital, Hartford, CT 06106, USA
    Neuroimage 48:738-46. 2009
    ....
  49. pmc Does function follow form?: methods to fuse structural and functional brain images show decreased linkage in schizophrenia
    Andrew M Michael
    The MIND Research Network, Albuquerque, NM 87106, USA
    Neuroimage 49:2626-37. 2010
    ..Results from all three methods indicate that the linkage between gray matter and functional activation is stronger in HC than SZ. The methods introduced can be easily extended to comprehensively correlate large data sets...
  50. pmc A large scale (N=400) investigation of gray matter differences in schizophrenia using optimized voxel-based morphometry
    Shashwath A Meda
    Olin Neuropsychiatry Research Center, Institute of Living at Hartford Hospital, Hartford, CT 06106, USA
    Schizophr Res 101:95-105. 2008
    ..However, results from these studies vary widely, likely due to different methodological or statistical approaches...
  51. pmc Physiogenomic analysis of localized FMRI brain activity in schizophrenia
    Andreas Windemuth
    Genomas, Inc, Hartford, CT, 06106, USA
    Ann Biomed Eng 36:877-88. 2008
    ..The results of this study support the physiogenomic analysis of neuroimaging data to discover associations between genotype and disease-related phenotypes...
  52. ncbi request reprint fMRI in an oddball task: effects of target-to-target interval
    Michael C Stevens
    Olin Neuropsychiatry Research Center, The Institute of Living, Hartford, Connecticut 06106, USA
    Psychophysiology 42:636-42. 2005
    ..There was no such effect of novel interval, suggesting that neuronal modulation may only occur for task-relevant stimuli, possibly in the service of strategic resource allocation processes...
  53. pmc Hemispheric differences in hemodynamics elicited by auditory oddball stimuli
    Michael C Stevens
    Olin Neuropsychiatry Research Center, The Institute of Living, Hartford, CT 06106, USA Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06510, USA
    Neuroimage 26:782-92. 2005
    ..The results (1) support the proposal that the right hemisphere is differentially engaged in processing salient stimuli and (2) demonstrate the successful use of a new voxel-based laterality analysis technique for fMRI data...
  54. ncbi request reprint A functional magnetic resonance imaging study of working memory abnormalities in schizophrenia
    Matthew R Johnson
    Olin Neuropsychiatry Research Center, The Institute of Living at Hartford Hospital, Hartford, CT, USA
    Biol Psychiatry 60:11-21. 2006
    ..We examined neural function changes at several WM loads to derive a more complete picture of WM dysfunction in schizophrenia...
  55. ncbi request reprint Abnormal object recall and anterior cingulate overactivation correlate with formal thought disorder in schizophrenia
    Michal Assaf
    Olin Neuropsychiatry Research Center, Institute of Living, Hartford, CT 06106, USA
    Biol Psychiatry 59:452-9. 2006
    ..An influential theory is that FTD results from impaired semantic memory processing. We explored the neural correlates of semantic memory retrieval in schizophrenia using an imaging task assessing semantic object recall...
  56. doi request reprint Biophysical modeling of phase changes in BOLD fMRI
    Zhaomei Feng
    The MIND Research Network, 1101 Yale Blvd NE, Albuquerque, NM 87131, New Mexico, USA
    Neuroimage 47:540-8. 2009
    ....
  57. ncbi request reprint Source density-driven independent component analysis approach for fMRI data
    Baoming Hong
    Olin Neuropsychiatry Research Center, Institute of Living, Hartford, Connecticut 06106, USA
    Hum Brain Mapp 25:297-307. 2005
    ..Our experimental results show that the source density-driven ICA method can improve performance further by incorporating some a priori information into ICA analysis of fMRI signals...
  58. pmc Joint source based morphometry identifies linked gray and white matter group differences
    Lai Xu
    The MIND Research Network, Albuquerque, New Mexico 87131, USA
    Neuroimage 44:777-89. 2009
    ..This approach is applicable to a wide variety of problems to study linked gray and white matter group differences...
  59. pmc Brain connectivity is not only lower but different in schizophrenia: a combined anatomical and functional approach
    Pawel Skudlarski
    Olin Neuropsychiatry Research Center, Institute of Living, Hartford Hospital, Hartford, Connecticut 06106, USA
    Biol Psychiatry 68:61-9. 2010
    ..Simultaneous measure of anatomical and functional connectivity and its interactions allow for better understanding of schizophrenia-related alternations in brain connectivity...
  60. pmc Anomalous neural circuit function in schizophrenia during a virtual Morris water task
    Bradley S Folley
    The Olin Neuropsychiatry Research Center, Hartford, CT, USA
    Neuroimage 49:3373-84. 2010
    ..GLM analysis elucidated several comparable regions, with the exception of the hippocampus. Inefficient allocentric learning and memory in patients may be related to an inability to recruit appropriate task-dependent neural circuits...
  61. pmc A method to fuse fMRI tasks through spatial correlations: applied to schizophrenia
    Andrew M Michael
    The MIND Research Network, Albuquerque, NM 87131, USA
    Hum Brain Mapp 30:2512-29. 2009
    ..The approach introduced finds interesting results and new differential features that cannot be achieved through traditional methods...
  62. ncbi request reprint Functional MRI study of a serial reaction time task in Huntington's disease
    Jin Suh Kim
    Olin Neuropsychiatry Research Center, Institute of Living, Hartford Hospital, 400 Washington St, Hartford, CT 06106, USA
    Psychiatry Res 131:23-30. 2004
    ..The variable striatal activity in the Huntington's group suggests early functional loss possibly associated with previously demonstrated early atrophy of these same neural structures...
  63. pmc Genetic determinants of target and novelty-related event-related potentials in the auditory oddball response
    Jingyu Liu
    The MIND Research Network, Albuquerque, NM 87131, USA
    Neuroimage 46:809-16. 2009
    ..These results provide evidence of genetic influences on normal patterns of ERP generation during auditory target detection and novelty processing at the SNP association level...
  64. pmc Identification of genetic and epigenetic marks involved in population structure
    Jingyu Liu
    The MIND Research Network, Albuquerque, New Mexico, United States of America
    PLoS ONE 5:e13209. 2010
    ....
  65. ncbi request reprint Structural and functional magnetic resonance imaging in psychiatric disorders
    Godfrey D Pearlson
    Olin Neuropsychiatry Research Center, Institute of Living, Hartford, Connecticut 06106, USA
    Can J Psychiatry 52:158-66. 2007
    ..To report on recent advances in both structural and functional brain imaging studies in psychiatry and to highlight their importance for the field...
  66. ncbi request reprint Voxel-based morphometry versus region of interest: a comparison of two methods for analyzing gray matter differences in schizophrenia
    Nicole R Giuliani
    Olin Neuropsychiatry Research Center, Institute of Living at Hartford Hospital, Whitehall Building, 200 Retreat Avenue, Hartford, CT 06106, USA
    Schizophr Res 74:135-47. 2005
    ..Although VBM is rapid and fully automated, it is not a replacement for manual ROI-based analyses. Both methods provide different types of information and should thus be used in tandem...
  67. ncbi request reprint A method for comparing group fMRI data using independent component analysis: application to visual, motor and visuomotor tasks
    Vince D Calhoun
    Olin Neuropsychiatry Research Center, Institute of Living, Hartford, CT 06106, USA
    Magn Reson Imaging 22:1181-91. 2004
    ..The proposed method may prove to be useful in answering questions requiring multigroup comparisons when a flexible modeling approach is desired...
  68. ncbi request reprint Alcohol intoxication effects on visual perception: an fMRI study
    Vince D Calhoun
    Olin Neuropsychiatry Research Center, Institute of Living, Hartford, Connecticut 06106, USA
    Hum Brain Mapp 21:15-26. 2004
    ..e., increased in spatial extent) at the higher dose. Alcohol, thus, appears to have both global and local effects upon the neural correlates of the MVPT-R task, some of which are dose dependent...
  69. pmc Voxel-based morphometric multisite collaborative study on schizophrenia
    Judith M Segall
    The MIND Research Network, Albuquerque, NM 87131, USA
    Schizophr Bull 35:82-95. 2009
    ....
  70. pmc Interrater and intermethod reliability of default mode network selection
    Alexandre R Franco
    The MIND Research Network, Albuquerque, New Mexico
    Hum Brain Mapp 30:2293-303. 2009
    ..The latter was significantly improved via a weighted combination of the anterior and posterior cingulate nodes of the DMN. Implications for fully automating the component selection process are discussed...
  71. doi request reprint Measuring brain connectivity: diffusion tensor imaging validates resting state temporal correlations
    Pawel Skudlarski
    Olin Neuropsychiatry Research Center, Institute of Living, Hartford Hospital, Hartford, 06106 CT, USA
    Neuroimage 43:554-61. 2008
    ..The combination of both techniques presented here allows for further combining them to provide richer representation of brain connectivity both in the healthy brain and in clinical conditions...
  72. pmc An fMRI study of working memory in first-degree unaffected relatives of schizophrenia patients
    Shashwath A Meda
    Olin Neuropsychiatry Research Center, Institute of Living at Hartford Hospital, 200 Retreat Avenue, Hartford, CT 06106, USA
    Schizophr Res 104:85-95. 2008
    ..Additionally, fMRI differences in both conditions were modulated by load, with a parametric increase in between-group differences with load in several key regions during encoding and an opposite effect during response selection...
  73. pmc Disruptions in functional network connectivity during alcohol intoxicated driving
    Catherine I Rzepecki-Smith
    Olin Neuropsychiatry Research Center, Institute of Living Hartford Hospital, Hartford, Connecticut, USA
    Alcohol Clin Exp Res 34:479-87. 2010
    ..However, the functional connectivity between these circuits has not yet been explored in order to determine how these networks communicate with each other during sober and alcohol-intoxicated states...
  74. pmc Effects of alcohol on performance on a distraction task during simulated driving
    Allyssa J Allen
    Olin Neuropsychiatry Research Center, Institute of Living at Hartford Hospital, 200 Retreat Avenue, Hartford, Connecticut 06106, USA
    Alcohol Clin Exp Res 33:617-25. 2009
    ..Previous functional MRI (fMRI) studies of the VO task have shown activation in the anterior cingulate, hippocampus, and prefrontal cortex. Thus, we predicted dose-dependent decreases in activation of these areas during VO performance...
  75. doi request reprint Changes in the interaction of resting-state neural networks from adolescence to adulthood
    Michael C Stevens
    Olin Neuropsychiatry Research Center, Institute of Living Hartford Hospital, Hartford, Connecticut 06106, USA
    Hum Brain Mapp 30:2356-66. 2009
    ..These results contribute to an emerging understanding that activity in widely distributed networks thought to underlie complex cognition influences activity in other networks...
  76. ncbi request reprint Estimating the number of independent components for functional magnetic resonance imaging data
    Yi Ou Li
    Department of Computer Science and Electrical Engineering, University of Maryland, Baltimore County, Baltimore, Maryland 21250, USA
    Hum Brain Mapp 28:1251-66. 2007
    ....
  77. ncbi request reprint Different activation dynamics in multiple neural systems during simulated driving
    Vince D Calhoun
    Division of Psychiatric Neuro Imaging, Department of Psychiatry, Johns Hopkins University, Baltimore, Maryland 21205, USA
    Hum Brain Mapp 16:158-67. 2002
    ..Increases in cerebellar and occipital areas, presumably related to complex visuomotor integration, are activated during driving but not associated with driving speed...
  78. ncbi request reprint Correlation of reaction time in and out of the functional MR unit
    Nina Mikhelashvili-Browner
    Acad Radiol 9:513-9. 2002
    ..The authors performed this study to determine whether reaction times (RTs) recorded in the functional magnetic resonance (MR) imaging environment reflect the performance of the patient outside the imaging room...
  79. ncbi request reprint Lack of sex effect on brain activity during a visuomotor response task: functional MR imaging study
    Nina Mikhelashvili-Browner
    Johns Hopkins Hospital, The Russell H Morgan Department of Radiology and Radiological Sciences, Division of Neuroradiology, Baltimore, MD 21205, USA
    AJNR Am J Neuroradiol 24:488-94. 2003
    ..As more individuals are enrolled in clinical functional MR imaging (fMRI) studies, an understanding of how sex may influence fMRI-measured brain activation is critical...
  80. ncbi request reprint Effect of age on visuomotor functional MR imaging
    Aylin Tekes
    Johns Hopkins Hospital, The Russell H Morgan Department of Radiology and Radiological Sciences, Division of Neuroradiology, 600 N Wolfe Street Phipps B 112, Baltimore, MD 21287, USA
    Acad Radiol 12:739-45. 2005
    ..We sought to determine the effect of age on functional MR imaging experiments performed with visual and motor stimulation. We hypothesized that there would be a diminution in the amplitude of fMRI activation with increasing subjects' age...
  81. pmc Prediction of human errors by maladaptive changes in event-related brain networks
    Tom Eichele
    Department of Biological and Medical Psychology, University of Bergen, 5009 Bergen, Norway
    Proc Natl Acad Sci U S A 105:6173-8. 2008
    ..Our findings provide insights into the brain network dynamics preceding human performance errors and suggest that monitoring of the identified precursor states may help in avoiding human errors in critical real-world situations...
  82. pmc Selective changes of resting-state networks in individuals at risk for Alzheimer's disease
    Christian Sorg
    Department of Psychiatry, Klinikum rechts der Isar, Technische Universitat Munchen, Ismaningerstrasse 22, 81675 Munich, Germany
    Proc Natl Acad Sci U S A 104:18760-5. 2007
    ..We interpret our finding as a proof of principle, demonstrating that functional brain disorders can be characterized by functional-disconnectivity profiles of RSNs...
  83. ncbi request reprint Functional classification of schizophrenia using feed forward neural networks
    Madiha J Jafri
    Olin Neuropsychiatry Research Center at the Institute of Living in Hartford, CT 06012, USA
    Conf Proc IEEE Eng Med Biol Soc . 2006
    ..A reliable technique for discriminating schizophrenia based upon fMRI would be a significant advance and may also provide additional information about the biological implications of mental illness...
  84. pmc Joint independent component analysis for simultaneous EEG-fMRI: principle and simulation
    Matthias Moosmann
    Department of Biological and Medical Psychology, University of Bergen, Jonas Lies vei 91, 5011 Bergen, Norway
    Int J Psychophysiol 67:212-21. 2008
    ..Our results indicate that this approach is a feasible and physiologically plausible data-driven way to achieve spatiotemporal mapping of event related responses in the human brain...
  85. ncbi request reprint Alterations in memory networks in mild cognitive impairment and Alzheimer's disease: an independent component analysis
    Kim A Celone
    Memory Disorders Unit, Department of Neurology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Neurosci 26:10222-31. 2006
    ..These data may also provide functional evidence of the interaction between neocortical and medial temporal lobe pathology in early AD...
  86. pmc Unmixing concurrent EEG-fMRI with parallel independent component analysis
    Tom Eichele
    Department of Biological and Medical Psychology, University of Bergen, Jonas Lies vei 91, 5011 Bergen, Norway
    Int J Psychophysiol 67:222-34. 2008
    ..We illustrate the utility of this method by extracting a previously undetected but relevant EEG-fMRI component from a concurrent auditory target detection experiment...
  87. pmc Performance of blind source separation algorithms for fMRI analysis using a group ICA method
    Nicolle Correa
    Department of Computer Science and Electrical Engineering, University of Maryland, Baltimore County, Baltimore, MD 21250, USA
    Magn Reson Imaging 25:684-94. 2007
    ..Our results greatly improve our confidence in the consistency of ICA for fMRI data analysis...

Research Grants19

  1. A Unified Framework for Flexible Brain Image Analysis
    Vince Calhoun; Fiscal Year: 2009
    ..This has application not only in schizophrenia but in many other diseases such as Alzheimer's, attention deficit hyperactivity, and psychopathy. ..
  2. A Unified Framework for Flexible Brain Image Analysis
    Vince D Calhoun; Fiscal Year: 2010
    ..This has application not only in schizophrenia but in many other diseases such as Alzheimer's, attention deficit hyperactivity, and psychopathy. ..
  3. Multivariate methods for identifying multi-task/multimodal brain imaging biomarke
    Vince D Calhoun; Fiscal Year: 2010
    ....
  4. Multivariate methods for identifying multi-task/multimodal brain imaging biomarke
    Vince Calhoun; Fiscal Year: 2007
    ..abstract_text> ..
  5. Multi-group semi-blind ICA of fMRI
    Vince Calhoun; Fiscal Year: 2006
    ....
  6. Multivariate methods for identifying multi-task/multimodal brain imaging biomarke
    Vince Calhoun; Fiscal Year: 2007
    ....
  7. CRCNS: Collaborative Research: Spatiotemporal Fusion of fMRI, EEG, and Genetic
    Vince Calhoun; Fiscal Year: 2007
    ..We plan to develop a toolbox that enables fusion and analysis of various types of imaging data and allows the incorporation of prior information and make it available to the research community though a website. ..
  8. Informed Data-Driven Fusion of Behavior, Brain Function, and Genes
    Vince D Calhoun; Fiscal Year: 2010
    ..Our methods will be implemented in a user-friendly software toolbox with anonymized data provided. 37 ..