Research Topics
Species | LILIAN CALDERON-GARCIDUENASSummaryAffiliation: University of Montana Country: USA Publications
Research Grants
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Detail Information
Publications
Early Alzheimer's and Parkinson's disease pathology in urban children: Friend versus Foe responses--it is time to face the evidenceLILIAN CALDERON-GARCIDUENAS
Center for Structural and Functional Neurosciences, The University of Montana, 32 Campus Drive, Skaggs Building 287, Missoula, MT 59812, USA
Biomed Res Int 2013:161687. 2013....
White matter hyperintensities, systemic inflammation, brain growth, and cognitive functions in children exposed to air pollutionLILIAN CALDERON-GARCIDUENAS
Instituto Nacional de Pediatria, Mexico City, Mexico
J Alzheimers Dis 31:183-91. 2012....- Neuroinflammation, hyperphosphorylated tau, diffuse amyloid plaques, and down-regulation of the cellular prion protein in air pollution exposed children and young adultsLILIAN CALDERON-GARCIDUENAS
Instituto Nacional de Pediatria, Mexico City, Mexico
J Alzheimers Dis 28:93-107. 2012..Together, these data support a role for air pollution in CNS damage and its impact upon the developing brain and the potential etiology of AD and mood disorders... - Air pollution is associated with brainstem auditory nuclei pathology and delayed brainstem auditory evoked potentialsLILIAN CALDERON-GARCIDUENAS
Instituto Nacional de Pediatria, Mexico City 04530, Mexico
Int J Dev Neurosci 29:365-75. 2011..Medial superior olive neurons, critically involved in BAEPs, displayed significant pathology. Children's exposure to urban air pollution increases their risk for auditory and vestibular impairment... - Effects of a cyclooxygenase-2 preferential inhibitor in young healthy dogs exposed to air pollution: a pilot studyLILIAN CALDERON-GARCIDUENAS
Instituto Nacional de Pediatria, Mexico City, Mexico
Toxicol Pathol 37:644-60. 2009..The search for potentially beneficial drugs useful to ameliorate the brain effects of pollution represents an enormous clinical challenge... - Urban air pollution: influences on olfactory function and pathology in exposed children and young adultsLILIAN CALDERON-GARCIDUENAS
Instituto Nacional de Pediatria, Mexico City 04530, Mexico
Exp Toxicol Pathol 62:91-102. 2010..This study contributes to our understanding of the influences of air pollution on olfaction and its potential contribution to neurodegeneration... - Immunotoxicity and environment: immunodysregulation and systemic inflammation in childrenLILIAN CALDERON-GARCIDUENAS
Instituto Nacional de Pediatria, Mexico City, Mexico
Toxicol Pathol 37:161-9. 2009..5). Exposure to urban air pollution is associated with immunodysregulation and systemic inflammation in children and is a major health threat... - Air pollution, cognitive deficits and brain abnormalities: a pilot study with children and dogsLILIAN CALDERON-GARCIDUENAS
Instituto Nacional de Pediatria, Mexico City, Mexico
Brain Cogn 68:117-27. 2008..The present work presents a groundbreaking, interdisciplinary methodology for addressing relationships between environmental pollution, structural brain alterations by MRI, and cognitive deficits/delays in healthy children... - Long-term air pollution exposure is associated with neuroinflammation, an altered innate immune response, disruption of the blood-brain barrier, ultrafine particulate deposition, and accumulation of amyloid beta-42 and alpha-synuclein in children and younLILIAN CALDERON-GARCIDUENAS
Instituto Nacional de Pediatria, Mexico City, Mexico
Toxicol Pathol 36:289-310. 2008..Exposure to air pollution should be considered a risk factor for Alzheimer's and Parkinson's diseases, and carriers of the APOE 4 allele could have a higher risk of developing Alzheimer's disease if they reside in a polluted environment... - Urban air pollution targets the dorsal vagal complex and dark chocolate offers neuroprotectionRafael Villarreal-Calderon
Davidson Honors College, University of Montana, 32 Campus Drive, 287 Skaggs Bldg, Missoula, MT 59812, USA
Int J Toxicol 29:604-15. 2010..002) and significant DVC imbalance in genes for antioxidant defenses, apoptosis, and neurodegeneration. These findings demonstrate sustained DVC inflammation in mice exposed to MC air, which is mitigated by chocolate administration... - Exposure to severe urban air pollution influences cognitive outcomes, brain volume and systemic inflammation in clinically healthy childrenLILIAN CALDERON-GARCIDUENAS
Instituto Nacional de Pediatria, Mexico City 04530, Mexico
Brain Cogn 77:345-55. 2011..Together these findings reveal that exposure to air pollution may perturb the trajectory of cerebral development and result in cognitive deficits during childhood... 
Brain inflammation and Alzheimer's-like pathology in individuals exposed to severe air pollutionLILIAN CALDERON-GARCIDUENAS
Instituto Nacional de Pediatria, Mexico City 14410, Mexico
Toxicol Pathol 32:650-8. 2004....- Urban air pollution produces up-regulation of myocardial inflammatory genes and dark chocolate provides cardioprotectionRodolfo Villarreal-Calderon
Department of Biomedical and Pharmaceutical Sciences, College of Health Professions and Biomedical Sciences, The University of Montana, Missoula, MT 59812, USA
Exp Toxicol Pathol 64:297-306. 2012..Regular consumption of dark chocolate may reduce myocardial inflammation and have cardioprotective properties in the setting of air pollution exposures... - Lung radiology and pulmonary function of children chronically exposed to air pollutionLILIAN CALDERON-GARCIDUENAS
Instituto Nacional de Pediatria, Mexico City, Mexico
Environ Health Perspect 114:1432-7. 2006..The epidemiologic implications of these findings are important for children residing in polluted environments, because bronchiolar disease could lead to chronic pulmonary disease later in life... - Assessment of physical education time and after-school outdoor time in elementary and middle school students in south Mexico City: the dilemma between physical fitness and the adverse health effects of outdoor pollutant exposureAnna Villarreal-Calderon
Facultad de Medicina, Programa NUCE, Universidad Nacional Autonoma de Mexico, Mexico City, Mexico
Arch Environ Health 57:450-60. 2002.... - Asbestos-induced autoimmunity in C57BL/6 miceJean C Pfau
Department of Biomedical and Pharmaceutical Sciences, University of Montana, Missoula, Montana 59812, USA
J Immunotoxicol 5:129-37. 2008..This study provides a non-autoimmune prone murine model for use in future elucidation of mechanisms involved in asbestos-induced autoimmune disease... - Pediatric respiratory and systemic effects of chronic air pollution exposure: nose, lung, heart, and brain pathologyLilian Calderon Garciduenas
Instituto Nacional de Pediatria, Mexico City, Mexico
Toxicol Pathol 35:154-62. 2007.... - Elevated plasma endothelin-1 and pulmonary arterial pressure in children exposed to air pollutionLilian Calderon Garciduenas
Instituto Nacional de Pediatria, Mexico City, Mexico
Environ Health Perspect 115:1248-53. 2007..Controlled exposures of animals and humans to particulate matter (PM) or ozone air pollution cause an increase in plasma levels of endothelin-1, a potent vasoconstrictor that regulates pulmonary arterial pressure...
Research Grants
- Neurotoxicity of Chronic Exposure to Air PollutionLilian Calderon Garciduenas; Fiscal Year: 2006..abstract_text> ..
- Air Pollution and Central Nervous System DiseaseLilian Calderon Garciduenas; Fiscal Year: 2007..The Award will give me the opportunity to build new skills in 4 areas: Molecular Biology, DNA Damage, Developmental / Neurodegenerative Neuropathology, and to gain experience in grantsmanship. ..