LILIAN CALDERON-GARCIDUENAS

Summary

Affiliation: University of Montana
Country: USA

Publications

  1. pmc Up-regulation of mRNA ventricular PRNP prion protein gene expression in air pollution highly exposed young urbanites: endoplasmic reticulum stress, glucose regulated protein 78, and nanosized particles
    Rodolfo Villarreal-Calderon
    Davidson Honors College, University of Montana, Missoula, MT 59812, USA
    Int J Mol Sci 14:23471-91. 2013
  2. doi request reprint Exposure to urban air pollution and bone health in clinically healthy six-year-old children
    LILIAN CALDERON-GARCIDUENAS
    The Center for Structural and Functional Neurosciences, The University of Montana, Missoula, MT 59812, USA
    Arh Hig Rada Toksikol 64:23-34. 2013
  3. pmc The impact of environmental metals in young urbanites' brains
    LILIAN CALDERON-GARCIDUENAS
    Instituto Nacional de Pediatria, Mexico City 04530, Mexico
    Exp Toxicol Pathol 65:503-11. 2013
  4. pmc Early Alzheimer's and Parkinson's disease pathology in urban children: Friend versus Foe responses--it is time to face the evidence
    LILIAN CALDERON-GARCIDUENAS
    Center for Structural and Functional Neurosciences, The University of Montana, 32 Campus Drive, Skaggs Building 287, Missoula, MT 59812, USA
    Biomed Res Int 2013:161687. 2013
  5. doi request reprint White matter hyperintensities, systemic inflammation, brain growth, and cognitive functions in children exposed to air pollution
    LILIAN CALDERON-GARCIDUENAS
    Instituto Nacional de Pediatria, Mexico City, Mexico
    J Alzheimers Dis 31:183-91. 2012
  6. doi request reprint Neuroinflammation, hyperphosphorylated tau, diffuse amyloid plaques, and down-regulation of the cellular prion protein in air pollution exposed children and young adults
    LILIAN CALDERON-GARCIDUENAS
    Instituto Nacional de Pediatria, Mexico City, Mexico
    J Alzheimers Dis 28:93-107. 2012
  7. pmc Air pollution is associated with brainstem auditory nuclei pathology and delayed brainstem auditory evoked potentials
    LILIAN CALDERON-GARCIDUENAS
    Instituto Nacional de Pediatria, Mexico City 04530, Mexico
    Int J Dev Neurosci 29:365-75. 2011
  8. doi request reprint Effects of a cyclooxygenase-2 preferential inhibitor in young healthy dogs exposed to air pollution: a pilot study
    LILIAN CALDERON-GARCIDUENAS
    Instituto Nacional de Pediatria, Mexico City, Mexico
    Toxicol Pathol 37:644-60. 2009
  9. pmc Urban air pollution: influences on olfactory function and pathology in exposed children and young adults
    LILIAN CALDERON-GARCIDUENAS
    Instituto Nacional de Pediatria, Mexico City 04530, Mexico
    Exp Toxicol Pathol 62:91-102. 2010
  10. doi request reprint Immunotoxicity and environment: immunodysregulation and systemic inflammation in children
    LILIAN CALDERON-GARCIDUENAS
    Instituto Nacional de Pediatria, Mexico City, Mexico
    Toxicol Pathol 37:161-9. 2009

Research Grants

  1. Neurotoxicity of Chronic Exposure to Air Pollution
    Lilian Calderon Garciduenas; Fiscal Year: 2006
  2. Air Pollution and Central Nervous System Disease
    Lilian Calderon Garciduenas; Fiscal Year: 2007

Collaborators

Detail Information

Publications23

  1. pmc Up-regulation of mRNA ventricular PRNP prion protein gene expression in air pollution highly exposed young urbanites: endoplasmic reticulum stress, glucose regulated protein 78, and nanosized particles
    Rodolfo Villarreal-Calderon
    Davidson Honors College, University of Montana, Missoula, MT 59812, USA
    Int J Mol Sci 14:23471-91. 2013
    ..Nanosized PM could play a key cardiac myocyte toxicity role. ..
  2. doi request reprint Exposure to urban air pollution and bone health in clinically healthy six-year-old children
    LILIAN CALDERON-GARCIDUENAS
    The Center for Structural and Functional Neurosciences, The University of Montana, Missoula, MT 59812, USA
    Arh Hig Rada Toksikol 64:23-34. 2013
    ..The selection of reference populations for DXA must take into account air pollution exposures...
  3. pmc The impact of environmental metals in young urbanites' brains
    LILIAN CALDERON-GARCIDUENAS
    Instituto Nacional de Pediatria, Mexico City 04530, Mexico
    Exp Toxicol Pathol 65:503-11. 2013
    ....
  4. pmc Early Alzheimer's and Parkinson's disease pathology in urban children: Friend versus Foe responses--it is time to face the evidence
    LILIAN CALDERON-GARCIDUENAS
    Center for Structural and Functional Neurosciences, The University of Montana, 32 Campus Drive, Skaggs Building 287, Missoula, MT 59812, USA
    Biomed Res Int 2013:161687. 2013
    ....
  5. doi request reprint White matter hyperintensities, systemic inflammation, brain growth, and cognitive functions in children exposed to air pollution
    LILIAN CALDERON-GARCIDUENAS
    Instituto Nacional de Pediatria, Mexico City, Mexico
    J Alzheimers Dis 31:183-91. 2012
    ....
  6. doi request reprint Neuroinflammation, hyperphosphorylated tau, diffuse amyloid plaques, and down-regulation of the cellular prion protein in air pollution exposed children and young adults
    LILIAN CALDERON-GARCIDUENAS
    Instituto Nacional de Pediatria, Mexico City, Mexico
    J Alzheimers Dis 28:93-107. 2012
    ..Together, these data support a role for air pollution in CNS damage and its impact upon the developing brain and the potential etiology of AD and mood disorders...
  7. pmc Air pollution is associated with brainstem auditory nuclei pathology and delayed brainstem auditory evoked potentials
    LILIAN CALDERON-GARCIDUENAS
    Instituto Nacional de Pediatria, Mexico City 04530, Mexico
    Int J Dev Neurosci 29:365-75. 2011
    ..Medial superior olive neurons, critically involved in BAEPs, displayed significant pathology. Children's exposure to urban air pollution increases their risk for auditory and vestibular impairment...
  8. doi request reprint Effects of a cyclooxygenase-2 preferential inhibitor in young healthy dogs exposed to air pollution: a pilot study
    LILIAN CALDERON-GARCIDUENAS
    Instituto Nacional de Pediatria, Mexico City, Mexico
    Toxicol Pathol 37:644-60. 2009
    ..The search for potentially beneficial drugs useful to ameliorate the brain effects of pollution represents an enormous clinical challenge...
  9. pmc Urban air pollution: influences on olfactory function and pathology in exposed children and young adults
    LILIAN CALDERON-GARCIDUENAS
    Instituto Nacional de Pediatria, Mexico City 04530, Mexico
    Exp Toxicol Pathol 62:91-102. 2010
    ..This study contributes to our understanding of the influences of air pollution on olfaction and its potential contribution to neurodegeneration...
  10. doi request reprint Immunotoxicity and environment: immunodysregulation and systemic inflammation in children
    LILIAN CALDERON-GARCIDUENAS
    Instituto Nacional de Pediatria, Mexico City, Mexico
    Toxicol Pathol 37:161-9. 2009
    ..5). Exposure to urban air pollution is associated with immunodysregulation and systemic inflammation in children and is a major health threat...
  11. doi request reprint Air pollution, cognitive deficits and brain abnormalities: a pilot study with children and dogs
    LILIAN CALDERON-GARCIDUENAS
    Instituto Nacional de Pediatria, Mexico City, Mexico
    Brain Cogn 68:117-27. 2008
    ..The present work presents a groundbreaking, interdisciplinary methodology for addressing relationships between environmental pollution, structural brain alterations by MRI, and cognitive deficits/delays in healthy children...
  12. doi request reprint Long-term air pollution exposure is associated with neuroinflammation, an altered innate immune response, disruption of the blood-brain barrier, ultrafine particulate deposition, and accumulation of amyloid beta-42 and alpha-synuclein in children and youn
    LILIAN CALDERON-GARCIDUENAS
    Instituto Nacional de Pediatria, Mexico City, Mexico
    Toxicol Pathol 36:289-310. 2008
    ..Exposure to air pollution should be considered a risk factor for Alzheimer's and Parkinson's diseases, and carriers of the APOE 4 allele could have a higher risk of developing Alzheimer's disease if they reside in a polluted environment...
  13. ncbi request reprint Pediatric respiratory and systemic effects of chronic air pollution exposure: nose, lung, heart, and brain pathology
    LILIAN CALDERON-GARCIDUENAS
    Instituto Nacional de Pediatria, Mexico City, Mexico
    Toxicol Pathol 35:154-62. 2007
    ....
  14. pmc Urban air pollution produces up-regulation of myocardial inflammatory genes and dark chocolate provides cardioprotection
    Rodolfo Villarreal-Calderon
    Department of Biomedical and Pharmaceutical Sciences, College of Health Professions and Biomedical Sciences, The University of Montana, Missoula, MT 59812, USA
    Exp Toxicol Pathol 64:297-306. 2012
    ..Regular consumption of dark chocolate may reduce myocardial inflammation and have cardioprotective properties in the setting of air pollution exposures...
  15. doi request reprint Urban air pollution targets the dorsal vagal complex and dark chocolate offers neuroprotection
    Rafael Villarreal-Calderon
    Davidson Honors College, University of Montana, 32 Campus Drive, 287 Skaggs Bldg, Missoula, MT 59812, USA
    Int J Toxicol 29:604-15. 2010
    ..002) and significant DVC imbalance in genes for antioxidant defenses, apoptosis, and neurodegeneration. These findings demonstrate sustained DVC inflammation in mice exposed to MC air, which is mitigated by chocolate administration...
  16. doi request reprint Exposure to severe urban air pollution influences cognitive outcomes, brain volume and systemic inflammation in clinically healthy children
    LILIAN CALDERON-GARCIDUENAS
    Instituto Nacional de Pediatria, Mexico City 04530, Mexico
    Brain Cogn 77:345-55. 2011
    ..Together these findings reveal that exposure to air pollution may perturb the trajectory of cerebral development and result in cognitive deficits during childhood...
  17. pmc Elevated plasma endothelin-1 and pulmonary arterial pressure in children exposed to air pollution
    LILIAN CALDERON-GARCIDUENAS
    Instituto Nacional de Pediatria, Mexico City, Mexico
    Environ Health Perspect 115:1248-53. 2007
    ..Controlled exposures of animals and humans to particulate matter (PM) or ozone air pollution cause an increase in plasma levels of endothelin-1, a potent vasoconstrictor that regulates pulmonary arterial pressure...
  18. pmc Lung radiology and pulmonary function of children chronically exposed to air pollution
    LILIAN CALDERON-GARCIDUENAS
    Instituto Nacional de Pediatria, Mexico City, Mexico
    Environ Health Perspect 114:1432-7. 2006
    ..The epidemiologic implications of these findings are important for children residing in polluted environments, because bronchiolar disease could lead to chronic pulmonary disease later in life...
  19. ncbi request reprint Brain inflammation and Alzheimer's-like pathology in individuals exposed to severe air pollution
    LILIAN CALDERON-GARCIDUENAS
    Instituto Nacional de Pediatria, Mexico City 14410, Mexico
    Toxicol Pathol 32:650-8. 2004
    ....
  20. ncbi request reprint Assessment of physical education time and after-school outdoor time in elementary and middle school students in south Mexico City: the dilemma between physical fitness and the adverse health effects of outdoor pollutant exposure
    Anna Villarreal-Calderon
    Facultad de Medicina, Programa NUCE, Universidad Nacional Autonoma de Mexico, Mexico City, Mexico
    Arch Environ Health 57:450-60. 2002
    ....
  21. doi request reprint Asbestos-induced autoimmunity in C57BL/6 mice
    Jean C Pfau
    Department of Biomedical and Pharmaceutical Sciences, University of Montana, Missoula, Montana 59812, USA
    J Immunotoxicol 5:129-37. 2008
    ..This study provides a non-autoimmune prone murine model for use in future elucidation of mechanisms involved in asbestos-induced autoimmune disease...
  22. ncbi request reprint Nasal squamous cell carcinoma in a child
    Jorge J Amador-Zarco
    Instituto Nacional de Pediatria, Mexico City, Mexico
    J Otolaryngol 31:45-9. 2002
  23. ncbi request reprint Arsenic exposure in pregnant mice disrupts placental vasculogenesis and causes spontaneous abortion
    Wenjie He
    Department of Biomedical and Pharmaceutical Sciences and Center for Environmental Health Sciences, The University of Montana, Missoula, Montana 59812, USA
    Toxicol Sci 99:244-53. 2007
    ..These results suggest that arsenic toxicity is causative for mammalian spontaneous abortion by virtue of aberrant placental vasculogenesis and placental insufficiency...

Research Grants4

  1. Neurotoxicity of Chronic Exposure to Air Pollution
    Lilian Calderon Garciduenas; Fiscal Year: 2006
    ..abstract_text> ..
  2. Air Pollution and Central Nervous System Disease
    Lilian Calderon Garciduenas; Fiscal Year: 2007
    ..The Award will give me the opportunity to build new skills in 4 areas: Molecular Biology, DNA Damage, Developmental / Neurodegenerative Neuropathology, and to gain experience in grantsmanship. ..