Joseph R Calabrese

Summary

Affiliation: University Hospitals Case Medical Center
Country: USA

Publications

  1. doi request reprint Adjunctive armodafinil for major depressive episodes associated with bipolar I disorder: a randomized, multicenter, double-blind, placebo-controlled, proof-of-concept study
    Joseph R Calabrese
    Department of Psychiatry, Case Western Reserve University, Cleveland, Ohio, USA
    J Clin Psychiatry 71:1363-70. 2010
  2. ncbi request reprint Agomelatine adjunctive therapy for acute bipolar depression: preliminary open data
    Joseph R Calabrese
    University Hospitals of Cleveland, Case Western Reserve University, Cleveland, OH 44106, USA
    Bipolar Disord 9:628-35. 2007
  3. doi request reprint PTSD comorbidity and suicidal ideation associated with PTSD within the Ohio Army National Guard
    Joseph R Calabrese
    Department of Psychiatry, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, Ohio, USA
    J Clin Psychiatry 72:1072-8. 2011
  4. doi request reprint Lamotrigine in the acute treatment of bipolar depression: results of five double-blind, placebo-controlled clinical trials
    Joseph R Calabrese
    Case Western Reserve University School of Medicine University Hospitals of Cleveland, Cleveland, OH, USA
    Bipolar Disord 10:323-33. 2008
  5. ncbi request reprint Clinical correlates of patients with rapid-cycling bipolar disorder and a recent history of substance use disorder: a subtype comparison from baseline data of 2 randomized, placebo-controlled trials
    Keming Gao
    Department of Psychiatry, Bipolar Disorder Research Center at the Mood Disorders Program, Case Western Reserve University School of Medicine, University Hospitals Case Medical Center, Cleveland, Ohio 44106, USA
    J Clin Psychiatry 69:1057-63. 2008
  6. doi request reprint Treatment-emergent mania/hypomania during antidepressant monotherapy in patients with rapid cycling bipolar disorder
    Keming Gao
    Department of Psychiatry, Bipolar Disorder Research Center at Mood Disorders Program, Case Western Reserve University School of Medicine, University Hospitals Case Medical Center, 10524 Euclid Avenue, Cleveland, OH 44106, USA
    Bipolar Disord 10:907-15. 2008
  7. pmc Lamotrigine adjunctive therapy to lithium and divalproex in depressed patients with rapid cycling bipolar disorder and a recent substance use disorder: a 12-week, double-blind, placebo-controlled pilot study
    Zuowei Wang
    Department of Psychiatry, Case Western Reserve University School of Medicine, Cleveland, OH, USA
    Psychopharmacol Bull 43:5-21. 2010
  8. pmc Clinical value of early partial symptomatic improvement in the prediction of response and remission during short-term treatment trials in 3369 subjects with bipolar I or II depression
    David E Kemp
    Case Western Reserve University, University Hospitals Case Medical Center, Cleveland, OH, USA
    J Affect Disord 130:171-9. 2011
  9. pmc Differential interactions between comorbid anxiety disorders and substance use disorder in rapid cycling bipolar I or II disorder
    Keming Gao
    Department of Psychiatry, Bipolar Disorder Research Center at Mood Disorders Program, Case Western Reserve University School of Medicine, University Hospitals Case Medical Center, Cleveland, Ohio, USA
    J Affect Disord 110:167-73. 2008
  10. pmc A 6-month, double-blind, maintenance trial of lithium monotherapy versus the combination of lithium and divalproex for rapid-cycling bipolar disorder and Co-occurring substance abuse or dependence
    David E Kemp
    Case Western Reserve University, University Hospitals Case Medical Center, Cleveland, Ohio, USA
    J Clin Psychiatry 70:113-21. 2009

Collaborators

Detail Information

Publications120 found, 100 shown here

  1. doi request reprint Adjunctive armodafinil for major depressive episodes associated with bipolar I disorder: a randomized, multicenter, double-blind, placebo-controlled, proof-of-concept study
    Joseph R Calabrese
    Department of Psychiatry, Case Western Reserve University, Cleveland, Ohio, USA
    J Clin Psychiatry 71:1363-70. 2010
    ..To evaluate the efficacy and safety of armodafinil, the longer-lasting isomer of modafinil, when used adjunctively in patients with bipolar depression...
  2. ncbi request reprint Agomelatine adjunctive therapy for acute bipolar depression: preliminary open data
    Joseph R Calabrese
    University Hospitals of Cleveland, Case Western Reserve University, Cleveland, OH 44106, USA
    Bipolar Disord 9:628-35. 2007
    ..The aim of this study was to gather preliminary data regarding the antidepressant efficacy of agomelatine in patients with bipolar I disorder experiencing a major depressive episode...
  3. doi request reprint PTSD comorbidity and suicidal ideation associated with PTSD within the Ohio Army National Guard
    Joseph R Calabrese
    Department of Psychiatry, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, Ohio, USA
    J Clin Psychiatry 72:1072-8. 2011
    ..To study the relation between posttraumatic stress disorder (PTSD) psychiatric comorbidity and suicidal ideation in a representative sample of Ohio Army National Guard soldiers...
  4. doi request reprint Lamotrigine in the acute treatment of bipolar depression: results of five double-blind, placebo-controlled clinical trials
    Joseph R Calabrese
    Case Western Reserve University School of Medicine University Hospitals of Cleveland, Cleveland, OH, USA
    Bipolar Disord 10:323-33. 2008
    ..This paper reports the results of five randomized, double-blind, placebo-controlled trials of lamotrigine monotherapy for the acute treatment of bipolar depression...
  5. ncbi request reprint Clinical correlates of patients with rapid-cycling bipolar disorder and a recent history of substance use disorder: a subtype comparison from baseline data of 2 randomized, placebo-controlled trials
    Keming Gao
    Department of Psychiatry, Bipolar Disorder Research Center at the Mood Disorders Program, Case Western Reserve University School of Medicine, University Hospitals Case Medical Center, Cleveland, Ohio 44106, USA
    J Clin Psychiatry 69:1057-63. 2008
    ..To compare clinical variables in patients with rapid-cycling bipolar I or II disorder and a recent history of substance use disorder (SUD)...
  6. doi request reprint Treatment-emergent mania/hypomania during antidepressant monotherapy in patients with rapid cycling bipolar disorder
    Keming Gao
    Department of Psychiatry, Bipolar Disorder Research Center at Mood Disorders Program, Case Western Reserve University School of Medicine, University Hospitals Case Medical Center, 10524 Euclid Avenue, Cleveland, OH 44106, USA
    Bipolar Disord 10:907-15. 2008
    ..To study treatment-emergent mania/hypomania (TEM) associated with second-generation antidepressant monotherapy in patients with rapid cycling bipolar disorder (RCBD)...
  7. pmc Lamotrigine adjunctive therapy to lithium and divalproex in depressed patients with rapid cycling bipolar disorder and a recent substance use disorder: a 12-week, double-blind, placebo-controlled pilot study
    Zuowei Wang
    Department of Psychiatry, Case Western Reserve University School of Medicine, Cleveland, OH, USA
    Psychopharmacol Bull 43:5-21. 2010
    ..To pilot the efficacy and safety data of lamotrigine adjunctive therapy to lithium and divalproex in patients with rapid-cycling bipolar disorder (RCBD) and a recent substance use disorder (SUD)...
  8. pmc Clinical value of early partial symptomatic improvement in the prediction of response and remission during short-term treatment trials in 3369 subjects with bipolar I or II depression
    David E Kemp
    Case Western Reserve University, University Hospitals Case Medical Center, Cleveland, OH, USA
    J Affect Disord 130:171-9. 2011
    ..To evaluate the clinical value of early partial symptomatic improvement in predicting the probability of response during the short-term treatment of bipolar depression...
  9. pmc Differential interactions between comorbid anxiety disorders and substance use disorder in rapid cycling bipolar I or II disorder
    Keming Gao
    Department of Psychiatry, Bipolar Disorder Research Center at Mood Disorders Program, Case Western Reserve University School of Medicine, University Hospitals Case Medical Center, Cleveland, Ohio, USA
    J Affect Disord 110:167-73. 2008
    ..Anxiety disorders (AD) and substance use disorders (SUD) commonly co-occur with bipolar disorder. This study was undertaken to assess AD-SUD-bipolar subtype interactions...
  10. pmc A 6-month, double-blind, maintenance trial of lithium monotherapy versus the combination of lithium and divalproex for rapid-cycling bipolar disorder and Co-occurring substance abuse or dependence
    David E Kemp
    Case Western Reserve University, University Hospitals Case Medical Center, Cleveland, Ohio, USA
    J Clin Psychiatry 70:113-21. 2009
    ....
  11. pmc Medical and substance use comorbidity in bipolar disorder
    David E Kemp
    Case Western Reserve University, University Hospitals Case Medical Center, Cleveland, OH, USA
    J Affect Disord 116:64-9. 2009
    ....
  12. pmc An open-label study of aripiprazole in children with a bipolar disorder
    Robert L Findling
    Department of Psychiatry, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, Ohio 44106, USA
    J Child Adolesc Psychopharmacol 21:345-51. 2011
    ..The purpose of this open-label study was to describe the effectiveness of aripiprazole (APZ) in the treatment of children with bipolar disorders suffering from manic symptomatology...
  13. ncbi request reprint Aripiprazole monotherapy for maintenance therapy in bipolar I disorder: a 100-week, double-blind study versus placebo
    Paul E Keck
    Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
    J Clin Psychiatry 68:1480-91. 2007
    ..Efficacy and tolerability of aripiprazole for relapse prevention in bipolar I disorder was, therefore, evaluated for 100 weeks...
  14. pmc Correlates of historical suicide attempt in rapid-cycling bipolar disorder: a cross-sectional assessment
    Keming Gao
    Department of Psychiatry, Case Western University School of Medicine, University Hospitals Case Medical Center, Cleveland, Ohio, USA
    J Clin Psychiatry 70:1032-40. 2009
    ..A rapid-cycling course in bipolar disorder has previously been identified as a risk factor for attempted suicide. This study investigated factors associated with suicide attempts in patients with rapid-cycling bipolar I or II disorder...
  15. pmc Predictors of non-stabilization during the combination therapy of lithium and divalproex in rapid cycling bipolar disorder: a post-hoc analysis of two studies
    Keming Gao
    Department of Psychiatry, Case Western Reserve University, Cleveland, OH, USA
    Psychopharmacol Bull 43:23-38. 2010
    ....
  16. ncbi request reprint A review of sensitivity and tolerability of antipsychotics in patients with bipolar disorder or schizophrenia: focus on somnolence
    Keming Gao
    Department of Psychiatry, Bipolar Disorder Research Center at Mood Disorders Program, University Hospitals Case Medical Center Case Western Reserve University, School of Medicine, Cleveland, Ohio, USA
    J Clin Psychiatry 69:302-9. 2008
    ..This study compared the sensitivity and tolerability of antipsychotics in patients with bipolar disorder or schizophrenia...
  17. ncbi request reprint Early symptoms of mania and the role of parental risk
    Robert L Findling
    Department of Psychiatry, University Hospitals of Cleveland, Case Western Reserve University, Cleveland, OH 44106, USA
    Bipolar Disord 7:623-34. 2005
    ....
  18. ncbi request reprint A placebo-controlled 18-month trial of lamotrigine and lithium maintenance treatment in recently depressed patients with bipolar I disorder
    Joseph R Calabrese
    University Hospitals of Cleveland Case Western Reserve School of Medicine, Department of Psychiatry, 11400 Euclid Ave, Ste 200, Cleveland, OH 44106, USA
    J Clin Psychiatry 64:1013-24. 2003
    ..This study assessed the efficacy and tolerability of lamotrigine and lithium compared with placebo for the prevention of mood episodes in bipolar disorder...
  19. ncbi request reprint Clinical highlights in bipolar depression: focus on atypical antipsychotics
    Joseph R Calabrese
    University Hospitals of Cleveland Case Western Reserve University School of Medicine, Cleveland, Ohio, USA
    J Clin Psychiatry 66:26-33. 2005
    ..In addition, direct comparison of the regimens used in the current study should determine whether the differences evident between them can be confirmed...
  20. ncbi request reprint Efficacy of typical and atypical antipsychotics for primary and comorbid anxiety symptoms or disorders: a review
    Keming Gao
    Department of Psychiatry, the Bipolar Disorders Research Center, University Hospitals of Cleveland Case Western Reserve University, School of Medicine, Cleveland, Ohio, USA
    J Clin Psychiatry 67:1327-40. 2006
    ..The efficacy of antipsychotics in the treatment of primary or comorbid anxiety disorders or anxiety symptoms in major depressive disorder or bipolar disorder was reviewed...
  21. ncbi request reprint Impact of lamotrigine and lithium on weight in obese and nonobese patients with bipolar I disorder
    Charles L Bowden
    Department of Psychiatry, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Dr, San Antonio, TX 78229 3900, USA
    Am J Psychiatry 163:1199-201. 2006
    ..This study assessed weight changes in a large cohort of patients with bipolar disorder who were treated with randomly assigned maintenance monotherapies...
  22. ncbi request reprint Phenomenology of rapid-cycling bipolar disorder: data from the first 500 participants in the Systematic Treatment Enhancement Program
    Christopher D Schneck
    Department of Psychiatry, University of Colorado Health Sciences Center, 4455 East 12th Ave, Box A011 15, Denver, CO 80220, USA
    Am J Psychiatry 161:1902-8. 2004
    ..This study compared demographic and phenomenological variables between bipolar patients with and without rapid cycling as a function of bipolar I versus bipolar II status...
  23. pmc Ziprasidone with adjunctive mood stabilizer in the maintenance treatment of bipolar I disorder: long-term changes in weight and metabolic profiles
    David E Kemp
    Case Western Reserve University, University Hospitals Case Medical Center, Cleveland, OH, USA
    Eur Neuropsychopharmacol 22:123-31. 2012
    ..Our findings suggest that MetS is highly prevalent in patients with bipolar disorder, may be associated with greater manic symptom severity, and may predict treatment outcomes...
  24. doi request reprint Lithium treatment -- moderate dose use study (LiTMUS) for bipolar disorder: rationale and design
    Andrew A Nierenberg
    Department of Psychiatry, Massachusetts General Hospital, Boston, MA 02114, USA
    Clin Trials 6:637-48. 2009
    ..Recent data indicate that lithium use for bipolar disorder has declined over the last decade and that lithium largely has been replaced with alternate, commercially promoted medications that may or may not result in better outcomes...
  25. ncbi request reprint A 20-month, double-blind, maintenance trial of lithium versus divalproex in rapid-cycling bipolar disorder
    Joseph R Calabrese
    Case Western Reserve University, University Hospitals of Cleveland, Cleveland, OH 44106, USA
    Am J Psychiatry 162:2152-61. 2005
    ..The authors tested the hypothesis that divalproex would be more effective than lithium in the long-term management of patients with recently stabilized rapid-cycling bipolar disorder...
  26. ncbi request reprint Relationship of open acute mania treatment to blinded maintenance outcome in bipolar I disorder
    Susan L McElroy
    Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    J Affect Disord 107:127-33. 2008
    ..No published studies have statistically evaluated the relationship between the outcomes in maintenance treatment and the principal acute agent...
  27. doi request reprint Evaluation and comparison of psychometric instruments for pediatric bipolar spectrum disorders in four age groups
    Thomas W Frazier
    Department of Psychiatry, University Hospitals Case Medical Center, Cleveland, OH, USA
    J Child Adolesc Psychopharmacol 17:853-66. 2007
    ..The CDRS-R may be better conceptualized as a two-factor measure in older adolescents. The semistructured K-SADS interview can be used to generate reliable diagnoses across a broad age range...
  28. pmc Independent predictors for lifetime and recent substance use disorders in patients with rapid-cycling bipolar disorder: focus on anxiety disorders
    Keming Gao
    Department of Psychiatry, Bipolar Disorder Research Center at Mood Disorders Program, Case Western Reserve University School of Medicine, University Hospitals Case Medical Center, Cleveland, Ohio 44106, USA
    Am J Addict 19:440-9. 2010
    ....
  29. ncbi request reprint Typical and atypical antipsychotics in bipolar depression
    Keming Gao
    Mood Disorders Program, Department of Psychiatry, University Hospitals of Cleveland, Case Western Reserve University School of Medicine, 11400 Euclid Avenue, Cleveland, OH 44106, USA
    J Clin Psychiatry 66:1376-85. 2005
    ..Since the antipsychotic agents have been shown to diminish depressive symptoms during the treatment of mania, atypical agents are now being studied for use in bipolar depression...
  30. pmc Lamotrigine as add-on treatment to lithium and divalproex: lessons learned from a double-blind, placebo-controlled trial in rapid-cycling bipolar disorder
    David E Kemp
    Department of Psychiatry, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, OH 44106, USA
    Bipolar Disord 14:780-9. 2012
    ..This study assessed the antidepressant effects of lamotrigine as compared with placebo when used as add-on therapy for rapid-cycling bipolar depression non-responsive to the combination of lithium plus divalproex...
  31. ncbi request reprint The Texas implementation of medication algorithms: update to the algorithms for treatment of bipolar I disorder
    Trisha Suppes
    Department of Psychiatry, The University of Texas Southwestern Medical Center, Dallas, TX 75390 9121, USA
    J Clin Psychiatry 66:870-86. 2005
    ..The guidelines for evaluating possible medications, the criteria for selection and ranking, and the updated algorithms are described...
  32. ncbi request reprint Newer treatment studies for bipolar depression
    Keming Gao
    NIMH Bipolar Research Center, Mood Disorders Program, University Hospitals of Cleveland Case Western Reserve University School of Medicine, Cleveland, OH, USA
    Bipolar Disord 7:13-23. 2005
    ..Depressive symptoms of bipolar disorder have more negative impact on a patient's life than manic symptoms. This review focused on the emerging efficacy data for treatments in bipolar depression...
  33. pmc Metabolic syndrome in patients enrolled in a clinical trial of aripiprazole in the maintenance treatment of bipolar I disorder: a post hoc analysis of a randomized, double-blind, placebo-controlled trial
    David E Kemp
    Case Western Reserve University School of Medicine, 10524 Euclid Ave, 12th Floor, Cleveland, OH 44106, USA
    J Clin Psychiatry 71:1138-44. 2010
    ..To compare the effects of maintenance treatment with aripiprazole or placebo on the incidence of metabolic syndrome in bipolar disorder...
  34. ncbi request reprint Double-blind 18-month trial of lithium versus divalproex maintenance treatment in pediatric bipolar disorder
    Robert L Findling
    Department of Psychiatry, Case Western Reserve University, USA
    J Am Acad Child Adolesc Psychiatry 44:409-17. 2005
    ....
  35. ncbi request reprint Prefrontal hemodynamic activity predicts false memory--a near-infrared spectroscopy study
    Yasutaka Kubota
    Mood Disorders Program, Department of Psychiatry, Case Western Reserve University University Hospitals of Cleveland, Cleveland, OH 44106, USA
    Neuroimage 31:1783-9. 2006
    ..Traces of semantic processing, reflected primarily in the left PFC activity, could eventually predict whether subjects falsely recognize non-experienced events...
  36. pmc Screening for bipolar disorder in a county jail at the time of criminal arrest
    David E Kemp
    Department of Psychiatry, Case Western Reserve University, Cleveland, OH 44106, USA
    J Psychiatr Res 42:778-86. 2008
    ..This study assessed the operating characteristics of the mood disorder questionnaire (MDQ) among offenders arrested and detained at a county jail...
  37. ncbi request reprint A randomized, placebo-controlled, multicenter study of divalproex sodium extended release in the treatment of acute mania
    Charles L Bowden
    Department of Psychiatry, University of Texas Health Science Center, San Antonio 78284 7792, USA
    J Clin Psychiatry 67:1501-10. 2006
    ..The efficacy and safety of divalproex sodium extended release (divalproex ER) were evaluated in patients hospitalized for acute mania associated with bipolar I disorder, manic or mixed type (DSM-IV-TR criteria)...
  38. ncbi request reprint Combination lithium and divalproex sodium in pediatric bipolar symptom re-stabilization
    Robert L Findling
    Department of Psychiatry, Case Western Reserve University, University Hospitals, Cleveland, OH 44106, USA
    J Am Acad Child Adolesc Psychiatry 45:142-8. 2006
    ..The primary goal of this study was to assess the rate of re-stabilization after the resumption of lithium (Li) plus divalproex (DVPX) following relapse on either agent as monotherapy...
  39. ncbi request reprint Maintenance efficacy of divalproex in the prevention of bipolar depression
    Laszlo Gyulai
    Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA
    Neuropsychopharmacology 28:1374-82. 2003
    ....
  40. doi request reprint Double-blind, randomized, placebo-controlled long-term maintenance study of aripiprazole in children with bipolar disorder
    Robert L Findling
    Department of Psychiatry, University Hospitals, Case Medical Center, Cleveland, OH 44106, USA
    J Clin Psychiatry 73:57-63. 2012
    ..This study evaluates the long-term efficacy of aripiprazole compared to placebo in children with bipolar disorders...
  41. pmc Predictors of bipolar disorder risk among patients currently treated for major depression
    Joseph R Calabrese
    Mood Disorders Program, Department of Psychiatry, Case Western Reserve University, University Hospitals of Cleveland, Cleveland, Ohio, USA
    MedGenMed 8:38. 2006
    ..The primary objective of this study was to assess the rate of bipolar disorder (BPD) risk among patients unsuccessfully treated for major depression and to identify predictors of bipolarity...
  42. ncbi request reprint Double-blind, placebo-controlled trial of divalproex monotherapy in the treatment of symptomatic youth at high risk for developing bipolar disorder
    Robert L Findling
    Department of Psychiatry, Case Western Reserve University, and the University Hospitals of Cleveland, Cleveland, Ohio 44106 5080, USA
    J Clin Psychiatry 68:781-8. 2007
    ..To determine if divalproex sodium was superior to placebo in the treatment of symptomatic youths who suffer from a bipolar spectrum disorder and who also have a parent with a diagnosis of a bipolar illness...
  43. ncbi request reprint Adherence to pharmacological treatment for juvenile bipolar disorder
    Dennis Drotar
    Department of Psychiatry, Case Western Reserve University, USA
    J Am Acad Child Adolesc Psychiatry 46:831-9. 2007
    ..The objective of this study was to describe the prevalence and correlates of adherence to divalproex sodium (DVPX) and lithium carbonate (Li) combination treatment during the initial stabilization treatment phase...
  44. pmc Medical comorbidity in bipolar disorder: relationship between illnesses of the endocrine/metabolic system and treatment outcome
    David E Kemp
    Case Western Reserve University, University Hospitals Case Medical Center, Cleveland, OH 44106, USA
    Bipolar Disord 12:404-13. 2010
    ..It was hypothesized that illnesses of the endocrine/metabolic system would be associated with greater psychiatric symptom burden and would impact the response to treatment with lithium and valproate...
  45. ncbi request reprint Recurrence in bipolar I disorder: a post hoc analysis excluding relapses in two double-blind maintenance studies
    Joseph R Calabrese
    Department of Psychiatry, Case Western Reserve University School of Medicine and University Hospitals of Cleveland, Cleveland, Ohio 44106, USA
    Biol Psychiatry 59:1061-4. 2006
    ..To assess the efficacy of lamotrigine or lithium in preventing mood recurrence (i.e., a new mood episode) in bipolar disorder...
  46. pmc Retrospective age at onset of bipolar disorder and outcome during two-year follow-up: results from the STEP-BD study
    Roy H Perlis
    Bipolar Clinical and Research Program, Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, ACC 812 15 Parkman Street, Boston, MA 02114, USA
    Bipolar Disord 11:391-400. 2009
    ..Symptoms of bipolar disorder are increasingly recognized among children and adolescents, but little is known about the course of bipolar disorder among adults who experience childhood onset of symptoms...
  47. ncbi request reprint A randomized, double-blind, placebo-controlled trial of quetiapine in the treatment of bipolar I or II depression
    Joseph R Calabrese
    University Hospitals of Cleveland and Case University School of Medicine, 11400 Euclid Ave, Suite 200, Cleveland, OH 44106, USA
    Am J Psychiatry 162:1351-60. 2005
    ..There is a major unmet need for effective options in the treatment of bipolar depression...
  48. ncbi request reprint Validation of the telephone-administered PHQ-9 against the in-person administered SCID-I major depression module
    Thomas H Fine
    Department of Psychiatry, University of Toledo, Toledo, Ohio 43614 2598, USA
    J Affect Disord 150:1001-7. 2013
    ..We assessed item-to-item correspondence between the Patient Health Questionnaire-9 (PHQ-9) and the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I) major depression episode portion of the major depressive module...
  49. doi request reprint Age differences in the phenomenology of pediatric bipolar disorder
    Christine A Demeter
    Department of Psychiatry, Case Western Reserve University, University Hospitals of Cleveland, OH, United States
    J Affect Disord 147:295-303. 2013
    ..The primary purpose of this study was to explore whether age differences in the phenomenology of bipolar disorders from 4 to 17 years of age exist...
  50. doi request reprint Risk for adverse events and discontinuation due to adverse events of ziprasidone monotherapy relative to placebo in the acute treatment of bipolar depression, mania, and schizophrenia
    Keming Gao
    Mood and Anxiety Clinic in the Mood Disorders Program of the Department of Psychiatry, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, OH 44106, USA
    J Clin Psychopharmacol 33:425-31. 2013
    ....
  51. pmc Use of insulin sensitizers for the treatment of major depressive disorder: a pilot study of pioglitazone for major depression accompanied by abdominal obesity
    David E Kemp
    Case Western Reserve University, University Hospitals Case Medical Center, Department of Psychiatry, Cleveland, OH 44106, USA
    J Affect Disord 136:1164-73. 2012
    ..This study was conducted to examine the safety and efficacy of pioglitazone, a thiazolidinedione insulin sensitizer, in adult outpatients with major depressive disorder...
  52. ncbi request reprint Relationship of mania symptomatology to maintenance treatment response with divalproex, lithium, or placebo
    Charles L Bowden
    Department of Psychiatry, University of Texas Health Science Center, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA
    Neuropsychopharmacology 30:1932-9. 2005
    ..Dysphoric mania appeared to predispose patients to more side effects when treated with either divalproex or lithium during maintenance therapy...
  53. pmc Suicidal ideation and depressive symptoms among bipolar patients as predictors of the health and well-being of caregivers
    Cheryl A Chessick
    Department of Psychiatry, University of Colorado Denver School of Medicine, Denver, CO 80045, USA
    Bipolar Disord 11:876-84. 2009
    ..This study examined whether caregivers' health is associated with changes in suicidal ideation and depressive symptoms among bipolar patients observed over one year...
  54. doi request reprint Quetiapine for the treatment of bipolar mania in older adults
    Martha Sajatovic
    Department of Psychiatry, Case Western Reserve University School of Medicine, University Hospitals of Cleveland, Cleveland, OH 44106, USA
    Bipolar Disord 10:662-71. 2008
    ..The primary efficacy endpoint was the change from baseline in Young Mania Rating Scale (YMRS) total score at Day 21. A secondary endpoint was change from baseline in YMRS score at Day 84...
  55. ncbi request reprint Does recovery from substance use disorder matter in patients with bipolar disorder?
    Roger D Weiss
    Department of Psychiatry, Harvard Medical School, Boston, USA
    J Clin Psychiatry 66:730-5; quiz 808-9. 2005
    ..To examine the potential impact of recovery from substance use disorder (SUD) on the course of bipolar disorder among patients diagnosed with both bipolar and substance use disorders according to DSM-IV criteria...
  56. pmc Number needed to treat to harm for discontinuation due to adverse events in the treatment of bipolar depression, major depressive disorder, and generalized anxiety disorder with atypical antipsychotics
    Keming Gao
    Department of Psychiatry, Mood and Anxiety Clinic in the Mood Disorders Program, University Hospitals Case Medical Center, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA
    J Clin Psychiatry 72:1063-71. 2011
    ....
  57. doi request reprint Acute efficacy of divalproex sodium versus placebo in mood stabilizer-naive bipolar I or II depression: a double-blind, randomized, placebo-controlled trial
    David J Muzina
    Department of Psychiatry and Psychology, Neurological Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA
    J Clin Psychiatry 72:813-9. 2011
    ..To conduct an exploratory evaluation of the acute efficacy of extended-release divalproex sodium compared to placebo in patients with bipolar I or II depression...
  58. pmc Stability of symptoms across major depressive episodes in bipolar disorder
    Roy H Perlis
    Bipolar Clinic and Research Program, Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Bipolar Disord 11:867-75. 2009
    ..These studies make the implicit assumption of stability of symptoms across episodes in mood disorders, which has rarely been investigated...
  59. pmc Initiation of stimulant and antidepressant medication and clinical presentation in juvenile bipolar I disorder
    Maria E Pagano
    Department of Psychiatry, University Hospitals of Cleveland, Case Western Reserve University School of Medicine, Cleveland, OH 44106 5080, USA
    Bipolar Disord 10:334-41. 2008
    ..Another aim was to investigate differences in clinical presentation between youths prescribed stimulant or antidepressant medication before and after the onset of juvenile BP I disorder...
  60. pmc Bipolar depression: trial-based insights to guide patient care
    David E Kemp
    Case Western Reserve University, University Hospitals Case Medical Center, Cleveland, Ohio, USA
    Dialogues Clin Neurosci 10:181-92. 2008
    ..A pragmatic clinical approach is presented for management of the depressed phase of bipolar disorder...
  61. doi request reprint A pilot pharmacotherapy trial for depressed youths at high genetic risk for bipolarity
    Robert L Findling
    Department of Psychiatry, University Hospitals Case Medical Center Case Western Reserve University, Cleveland, Ohio 44106, USA
    J Child Adolesc Psychopharmacol 18:615-21. 2008
    ..As a result, future treatment studies in this population appear to be warranted, not only due to the putative impending risk of developing bipolar disorder, but also the manifest risk of current depressive episodes...
  62. pmc Personal and societal construction of illness among individuals with rapid-cycling bipolar disorder: a life-trajectory perspective
    Martha Sajatovic
    Department of Psychiatry, Case Western Reserve University School of Medicine, Cleveland, OH, USA
    Am J Geriatr Psychiatry 16:718-26. 2008
    ..The purpose of this study was to examine the subjective experience of illness among 19 men and women with rapid cycling bipolar disorder receiving treatment at an academic psychiatry clinic...
  63. doi request reprint Clinical utility of early improvement to predict response or remission in acute mania: focus on olanzapine and risperidone
    David E Kemp
    Case Western Reserve University, University Hospitals Case Medical Center, Cleveland, OH 44106, USA
    J Clin Psychiatry 72:1236-41. 2011
    ..To evaluate early improvement associated with atypical antipsychotic treatment as a predictor of later response or remission among patients experiencing an acute manic or mixed episode without psychotic features...
  64. ncbi request reprint Treatment-emergent mania in unipolar and bipolar depression: focus on repetitive transcranial magnetic stimulation
    Guohua Xia
    Department of Psychiatry, Case Western Reserve University, Cleveland, OH 44106, USA
    Int J Neuropsychopharmacol 11:119-30. 2008
    ..More systematic studies are needed to better understand TEM associated with rTMS. Special precautions and measures should be adopted to prevent, monitor, and manage TEM in research and practice...
  65. ncbi request reprint Acute treatment of mania: an update on new medications
    Prashant Gajwani
    Case School of Medicine, Mood Disorders Program, University Hospitals Case Medical Center, 11400 Euclid Avenue, Suite 200, Cleveland, OH 44106, USA
    Curr Psychiatry Rep 8:504-9. 2006
    ....
  66. ncbi request reprint International Consensus Group on Bipolar I Depression Treatment Guidelines
    Joseph R Calabrese
    Department of Psychiatry, Case Western Reserve University, Cleveland, OH, USA
    J Clin Psychiatry 65:571-9. 2004
  67. ncbi request reprint Prefrontal activation during verbal fluency tests in schizophrenia--a near-infrared spectroscopy (NIRS) study
    Yasutaka Kubota
    Mood Disorders Program, Department of Psychiatry, Case Western Reserve University University Hospitals of Cleveland, Cleveland, OH, USA
    Schizophr Res 77:65-73. 2005
    ..The present study is the first to detect abnormal patterns of PFC activation in adults with schizophrenia in response to the distinct cognitive demands associated with letter and semantic VFT...
  68. ncbi request reprint Lamotrigine treatment of bipolar disorder: data from the first 500 patients in STEP-BD
    Lauren B Marangell
    Mood Disorders Program, Department of Psychiatry, Baylor College of Medicine, Houston, TX 77030, USA
    Bipolar Disord 6:139-43. 2004
    ..To describe the frequency and correlates of lamotrigine therapy among the first 500 patients enrolled into the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD) study...
  69. ncbi request reprint Employing parent, teacher, and youth self-report checklists in identifying pediatric bipolar spectrum disorders: an examination of diagnostic accuracy and clinical utility
    Shoshana Y Kahana
    Case Western Reserve University, Cleveland, Ohio 44106, USA
    J Child Adolesc Psychopharmacol 13:471-88. 2003
    ..Results indicate that the Child Behavior Checklist has limited utility when attempting to derive clinically meaningful information about the presentation of juvenile BPSD...
  70. ncbi request reprint Maintenance treatment outcomes in older patients with bipolar I disorder
    Martha Sajatovic
    Department of Psychiatry, Case University School of Medicine and University Hospitals of Cleveland, 11100 Euclid Avenue, Cleveland, OH 44106, USA
    Am J Geriatr Psychiatry 13:305-11. 2005
    ....
  71. ncbi request reprint Mood state at study entry as predictor of the polarity of relapse in bipolar disorder
    Joseph R Calabrese
    Case University School of Medicine, University Hospitals of Cleveland, 11400 Euclid Avenue, Suite 200, Cleveland, OH 44106, USA
    Biol Psychiatry 56:957-63. 2004
    ..We conclude that putative mood stabilizers must be tested in recently manic and recently depressed patients to determine their spectrum of prophylactic efficacy...
  72. ncbi request reprint A placebo-controlled 18-month trial of lamotrigine and lithium maintenance treatment in recently manic or hypomanic patients with bipolar I disorder
    Charles L Bowden
    Department of Psychiatry, University of Texas Health Science Center at San Antonio, 78229, USA
    Arch Gen Psychiatry 60:392-400. 2003
    ....
  73. ncbi request reprint A randomized, double-blind, placebo-controlled 26-week trial of aripiprazole in recently manic patients with bipolar I disorder
    Paul E Keck
    Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267, USA
    J Clin Psychiatry 67:626-37. 2006
    ..To investigate the safety and efficacy of aripiprazole in preventing relapse of a mood episode in recently manic- or mixed-episode patients with bipolar I disorder stabilized on aripiprazole...
  74. ncbi request reprint Effects of lamotrigine and lithium on body weight during maintenance treatment of bipolar I disorder
    Gary Sachs
    Department of Psychiatry, Harvard University, Harvard Bipolar Research Program, Massachusetts General Hospital, Boston, MA 02114, USA
    Bipolar Disord 8:175-81. 2006
    ....
  75. ncbi request reprint Rash in multicenter trials of lamotrigine in mood disorders: clinical relevance and management
    Joseph R Calabrese
    Department of Psychiatry, Case Western Reserve University University Hospitals of Cleveland, Cleveland, Ohio, USA
    J Clin Psychiatry 63:1012-9. 2002
    ..The objective of this report was to determine rash rates in clinical trials of lamotrigine in DSM-IV unipolar depression or bipolar disorder...
  76. ncbi request reprint Combination lithium and divalproex sodium in pediatric bipolarity
    Robert L Findling
    Department of Psychiatry, Case Western Reserve University School of Medicine, USA
    J Am Acad Child Adolesc Psychiatry 42:895-901. 2003
    ..Many youths with bipolar disorder do not respond to DVPX or Li monotherapy. An open-label study was conducted to examine the effectiveness of combination DVPX and Li therapy with youths diagnosed with bipolar disorder...
  77. ncbi request reprint Gender differences in criminality: bipolar disorder with co-occurring substance abuse
    Susan Hatters Friedman
    Department of Psychiatry, University Hospitals of Cleveland, Hanna Pavilion, 11100 Euclid Avenue, Cleveland, OH 44106, USA
    J Am Acad Psychiatry Law 33:188-95. 2005
    ..Implications from this pilot study include the need for earlier identification of bipolar disorder and for the increased availability of psychiatric and substance abuse services within correctional facilities...
  78. ncbi request reprint Antiepileptic drugs in mood-disordered patients
    Prashant Gajwani
    NIMH Bipolar Research Center, Case Western Reserve University School of Medicine, Mood Disorders Program, University Hospitals of Cleveland, OH, USA
    Epilepsia 46:38-44. 2005
    ..LTG seems to be effective against depression and mania, with a more robust activity against depression. No firm evidence supports a role for vigabatrin, tiagabine, topiramate, or levetiracetam in these disorders...
  79. pmc Antipsychotic-induced extrapyramidal side effects in bipolar disorder and schizophrenia: a systematic review
    Keming Gao
    Department of Psychiatry, Bipolar Disorder Research Center at the Mood Disorders Program, University Hospitals Case Medical Center Case Western Reserve University, School of Medicine, Cleveland, OH, USA
    J Clin Psychopharmacol 28:203-9. 2008
    ..This review is to compare antipsychotic-induced EPS relative to placebo in bipolar disorder (BPD) and schizophrenia...
  80. ncbi request reprint Overview of patient care issues and treatment in bipolar spectrum and bipolar II disorder
    Joseph R Calabrese
    Mood Disorders Program, Department of Psychiatry, Case Western Reserve University, University Hospitals of Cleveland, Ohio, USA
    J Clin Psychiatry 69:e18. 2008
    ....
  81. ncbi request reprint Recent placebo-controlled acute trials in bipolar depression: focus on methodology
    David J Muzina
    Cleveland Clinic Foundation, Cleveland, Ohio, USA
    Int J Neuropsychopharmacol 6:285-91. 2003
    ..Moclobemide monotherapy was similar in efficacy to imipramine (n=156), but had a lower rate of switching (4% vs. 11%)...
  82. ncbi request reprint Sex differences in pediatric bipolar disorder
    Jeanne M Duax
    Department of Psychology, Case Western Reserve University, Cleveland, OH 44106 7123, USA
    J Clin Psychiatry 68:1565-73. 2007
    ..To explore sex differences in pediatric bipolar disorder in terms of subtype and severity of depressive and manic symptomatology...
  83. ncbi request reprint Methylphenidate in the treatment of children and adolescents with bipolar disorder and attention-deficit/hyperactivity disorder
    Robert L Findling
    Department of Psychiatry, Case Western Reserve University, University Hospitals Case Medical Center, Cleveland, OH 44106 5080, USA
    J Am Acad Child Adolesc Psychiatry 46:1445-53. 2007
    ..To examine the short-term efficacy of methylphenidate in the treatment of youths with bipolar disorder (BD) and comorbid attention deficit/hyperactivity disorder (ADHD)...
  84. ncbi request reprint Comparing the diagnostic accuracy of six potential screening instruments for bipolar disorder in youths aged 5 to 17 years
    Eric A Youngstrom
    Department of Psychology, Case Western Reserve University, University Hospitals of Cleveland, Ohia 44106 7123, USA
    J Am Acad Child Adolesc Psychiatry 43:847-58. 2004
    ..To compare the diagnostic efficiency of six index tests as predictors of juvenile bipolar disorder in two large outpatient samples, aged 5 to 10 and 11 to 17 years, gathered from 1997 to 2002...
  85. pmc Atypical antipsychotics in primary generalized anxiety disorder or comorbid with mood disorders
    Keming Gao
    Department of Psychiatry, Mood and Anxiety Clinic in the Mood Disorders Program, Case Western Reserve University School of Medicine, University Hospitals Case Medical Center, Cleveland, OH 44106, USA
    Expert Rev Neurother 9:1147-58. 2009
    ..However, in contrast to antidepressants and benzodiazepines, the long-term risk and benefit of atypical antipsychotics in the treatment of GAD is yet to be determined...
  86. pmc A comparison of the life goals program and treatment as usual for individuals with bipolar disorder
    Martha Sajatovic
    Department of Psychiatry, Case Western Reserve University School of Medicine, 10524 Euclid Ave, Cleveland, OH 44106, USA
    Psychiatr Serv 60:1182-9. 2009
    ....
  87. ncbi request reprint Depression mood stabilisation: novel concepts and clinical management
    Joseph R Calabrese
    Case Western Reserve University, MD 11400 Euclid Avenue, Suite 200, Cleveland, OH 44106, USA
    Eur Neuropsychopharmacol 14:S100-7. 2004
    ..Lamotrigine represents a valuable addition to the current therapeutic armamentarium for bipolar disorder, allowing a therapeutic balance between the treatment of mania and depression...
  88. ncbi request reprint Comparing diagnostic checklists for pediatric bipolar disorder in academic and community mental health settings
    Eric Youngstrom
    Department of Psychology, Case Western Reserve University, Cleveland, OH 44106, USA
    Bipolar Disord 7:507-17. 2005
    ....
  89. ncbi request reprint Citalopram treatment of fluoxetine-intolerant depressed patients
    Joseph R Calabrese
    Mood Disorders Program, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA
    J Clin Psychiatry 64:562-7. 2003
    ..We assessed the tolerability of and response to citalopram in depressed patients who had discontinued fluoxetine treatment due to adverse events...
  90. ncbi request reprint Priority actions to improve the care of persons with co-occurring substance abuse and other mental disorders: a call to action
    CHARLES P O'BRIEN
    Department of Psychiatry, University of Pennsylvania School of Medicine, 3900 Chestnut Street, Philadelphia, PA 19104 6178, USA
    Biol Psychiatry 56:703-13. 2004
  91. ncbi request reprint A pooled analysis of 2 placebo-controlled 18-month trials of lamotrigine and lithium maintenance in bipolar I disorder
    Guy M Goodwin
    Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford OX3 7JX, England, UK
    J Clin Psychiatry 65:432-41. 2004
    ..Two clinical trials, prospectively designed for combined analysis, compared placebo, lithium, and lamotrigine for treatment of bipolar I disorder in recently depressed or manic patients...
  92. ncbi request reprint Pattern of response to divalproex, lithium, or placebo in four naturalistic subtypes of mania
    Alan C Swann
    University of Texas Houston Health Science Center, P O Box 20708, Houston, TX 77225, USA
    Neuropsychopharmacology 26:530-6. 2002
    ..These data suggest that there are naturalistic subtypes of manic episodes with different responses to treatment...
  93. ncbi request reprint Third generation anticonvulsants in bipolar disorder: a review of efficacy and summary of clinical recommendations
    Lakshmi N Yatham
    Department of Psychiatry, University of British Columbia, Vancouver, Canada
    J Clin Psychiatry 63:275-83. 2002
    ..To review the literature on efficacy of third generation anticonvulsants for treatment of bipolar disorder and provide clinical recommendations...
  94. ncbi request reprint Long-term treatment of bipolar disorder with lamotrigine
    Joseph R Calabrese
    J Clin Psychiatry 63:18-22. 2002
    ....
  95. ncbi request reprint Olanzapine in the acute treatment of bipolar I disorder with a history of rapid cycling
    Todd M Sanger
    Lilly Research Laboratories, Indianapolis, IN 46285, USA
    J Affect Disord 73:155-61. 2003
    ..A substantial proportion of patients with bipolar disorder are characterized by a rapidly cycling course and are particularly resistant to conventional treatment...
  96. ncbi request reprint Screening for bipolar disorder in the community
    Robert M A Hirschfeld
    Department of Psychiatry and Behavioral Sciences, University of Texas Medical Branch, Galveston, 77555 188, USA
    J Clin Psychiatry 64:53-9. 2003
    ..Our goal was to estimate the rate of positive screens for bipolar I and bipolar II disorders in the general population of the United States...
  97. ncbi request reprint Efficacy of quetiapine monotherapy in bipolar I and II depression: a double-blind, placebo-controlled study (the BOLDER II study)
    Michael E Thase
    Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA 15213 2593, USA
    J Clin Psychopharmacol 26:600-9. 2006
    ..This study demonstrates that quetiapine monotherapy is an effective and well-tolerated treatment for depressive episodes in bipolar disorder, confirming the results observed from a previous study (BipOLar DEpRession [BOLDER] I)...
  98. ncbi request reprint Stabilization of mood from below versus above baseline in bipolar disorder: a new nomenclature
    Terence A Ketter
    Department of Psychiatry and Behavioral Science, Stanford University School of Medicine, Calif 94305 5723, USA
    J Clin Psychiatry 63:146-51. 2002
    ..In this article, the treatment options for bipolar disorder, with a focus on depression and rapid cycling, are discussed according to this new conceptualization of management from below and above baseline...
  99. ncbi request reprint Relapse prevention in bipolar I disorder: 18-month comparison of olanzapine plus mood stabiliser v. mood stabiliser alone
    Mauricio Tohen
    Lilly Research Laboratories, Indianapolis, Indiana 46285, USA
    Br J Psychiatry 184:337-45. 2004
    ..Aims To evaluate whether olanzapine plus either lithium or valproate reduces the rate of relapse, compared with lithium or valproate alone...
  100. ncbi request reprint Psychosis in mania: specificity of its role in severity and treatment response
    Alan C Swann
    University of Texas Medical School, Houston 77030, USA
    J Clin Psychiatry 65:825-9. 2004
    ..Psychosis is a prominent characteristic of manic episodes. We investigated relationships between the presence of psychotic features, the severity of the manic syndrome, and syndrome severity's response to treatment...
  101. ncbi request reprint Pharmacotherapy for bipolar disorder and comorbid conditions: baseline data from STEP-BD
    Naomi M Simon
    Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    J Clin Psychopharmacol 24:512-20. 2004
    ..Our findings highlight the need for greater clinical guidance and treatment options for patients with bipolar disorder and comorbidity...