Research Topics
| Joseph R CalabreseSummaryAffiliation: University Hospitals Case Medical Center Country: USA Publications
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Detail Information
Publications
Adjunctive armodafinil for major depressive episodes associated with bipolar I disorder: a randomized, multicenter, double-blind, placebo-controlled, proof-of-concept studyJoseph R Calabrese
Department of Psychiatry, Case Western Reserve University, Cleveland, Ohio, USA
J Clin Psychiatry 71:1363-70. 2010..To evaluate the efficacy and safety of armodafinil, the longer-lasting isomer of modafinil, when used adjunctively in patients with bipolar depression...- Lamotrigine in the acute treatment of bipolar depression: results of five double-blind, placebo-controlled clinical trialsJoseph R Calabrese
Case Western Reserve University School of Medicine University Hospitals of Cleveland, Cleveland, OH, USA
Bipolar Disord 10:323-33. 2008..This paper reports the results of five randomized, double-blind, placebo-controlled trials of lamotrigine monotherapy for the acute treatment of bipolar depression... - PTSD comorbidity and suicidal ideation associated with PTSD within the Ohio Army National GuardJoseph R Calabrese
Department of Psychiatry, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, Ohio, USA
J Clin Psychiatry 72:1072-8. 2011..To study the relation between posttraumatic stress disorder (PTSD) psychiatric comorbidity and suicidal ideation in a representative sample of Ohio Army National Guard soldiers... 
Agomelatine adjunctive therapy for acute bipolar depression: preliminary open dataJoseph R Calabrese
University Hospitals of Cleveland, Case Western Reserve University, Cleveland, OH 44106, USA
Bipolar Disord 9:628-35. 2007..The aim of this study was to gather preliminary data regarding the antidepressant efficacy of agomelatine in patients with bipolar I disorder experiencing a major depressive episode...- Clinical correlates of patients with rapid-cycling bipolar disorder and a recent history of substance use disorder: a subtype comparison from baseline data of 2 randomized, placebo-controlled trialsKeming Gao
Department of Psychiatry, Bipolar Disorder Research Center at the Mood Disorders Program, Case Western Reserve University School of Medicine, University Hospitals Case Medical Center, Cleveland, Ohio 44106, USA
J Clin Psychiatry 69:1057-63. 2008..To compare clinical variables in patients with rapid-cycling bipolar I or II disorder and a recent history of substance use disorder (SUD)... - Treatment-emergent mania/hypomania during antidepressant monotherapy in patients with rapid cycling bipolar disorderKeming Gao
Department of Psychiatry, Bipolar Disorder Research Center at Mood Disorders Program, Case Western Reserve University School of Medicine, University Hospitals Case Medical Center, 10524 Euclid Avenue, Cleveland, OH 44106, USA
Bipolar Disord 10:907-15. 2008..To study treatment-emergent mania/hypomania (TEM) associated with second-generation antidepressant monotherapy in patients with rapid cycling bipolar disorder (RCBD)... 
Lamotrigine adjunctive therapy to lithium and divalproex in depressed patients with rapid cycling bipolar disorder and a recent substance use disorder: a 12-week, double-blind, placebo-controlled pilot studyZuowei Wang
Department of Psychiatry, Case Western Reserve University School of Medicine, Cleveland, OH, USA
Psychopharmacol Bull 43:5-21. 2010..To pilot the efficacy and safety data of lamotrigine adjunctive therapy to lithium and divalproex in patients with rapid-cycling bipolar disorder (RCBD) and a recent substance use disorder (SUD)...- Clinical value of early partial symptomatic improvement in the prediction of response and remission during short-term treatment trials in 3369 subjects with bipolar I or II depressionDavid E Kemp
Case Western Reserve University, University Hospitals Case Medical Center, Cleveland, OH, USA
J Affect Disord 130:171-9. 2011..To evaluate the clinical value of early partial symptomatic improvement in predicting the probability of response during the short-term treatment of bipolar depression... - Differential interactions between comorbid anxiety disorders and substance use disorder in rapid cycling bipolar I or II disorderKeming Gao
Department of Psychiatry, Bipolar Disorder Research Center at Mood Disorders Program, Case Western Reserve University School of Medicine, University Hospitals Case Medical Center, Cleveland, Ohio, USA
J Affect Disord 110:167-73. 2008..Anxiety disorders (AD) and substance use disorders (SUD) commonly co-occur with bipolar disorder. This study was undertaken to assess AD-SUD-bipolar subtype interactions... - Medical and substance use comorbidity in bipolar disorderDavid E Kemp
Case Western Reserve University, University Hospitals Case Medical Center, Cleveland, OH, USA
J Affect Disord 116:64-9. 2009.... - A 6-month, double-blind, maintenance trial of lithium monotherapy versus the combination of lithium and divalproex for rapid-cycling bipolar disorder and Co-occurring substance abuse or dependenceDavid E Kemp
Case Western Reserve University, University Hospitals Case Medical Center, Cleveland, Ohio, USA
J Clin Psychiatry 70:113-21. 2009.... - An open-label study of aripiprazole in children with a bipolar disorderRobert L Findling
Department of Psychiatry, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, Ohio 44106, USA
J Child Adolesc Psychopharmacol 21:345-51. 2011..The purpose of this open-label study was to describe the effectiveness of aripiprazole (APZ) in the treatment of children with bipolar disorders suffering from manic symptomatology... - Correlates of historical suicide attempt in rapid-cycling bipolar disorder: a cross-sectional assessmentKeming Gao
Department of Psychiatry, Case Western University School of Medicine, University Hospitals Case Medical Center, Cleveland, Ohio, USA
J Clin Psychiatry 70:1032-40. 2009..A rapid-cycling course in bipolar disorder has previously been identified as a risk factor for attempted suicide. This study investigated factors associated with suicide attempts in patients with rapid-cycling bipolar I or II disorder... - Aripiprazole monotherapy for maintenance therapy in bipolar I disorder: a 100-week, double-blind study versus placeboPaul E Keck
Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
J Clin Psychiatry 68:1480-91. 2007..Efficacy and tolerability of aripiprazole for relapse prevention in bipolar I disorder was, therefore, evaluated for 100 weeks... - Predictors of non-stabilization during the combination therapy of lithium and divalproex in rapid cycling bipolar disorder: a post-hoc analysis of two studiesKeming Gao
Department of Psychiatry, Case Western Reserve University, Cleveland, OH, USA
Psychopharmacol Bull 43:23-38. 2010.... - Early symptoms of mania and the role of parental riskRobert L Findling
Department of Psychiatry, University Hospitals of Cleveland, Case Western Reserve University, Cleveland, OH 44106, USA
Bipolar Disord 7:623-34. 2005.... - A review of sensitivity and tolerability of antipsychotics in patients with bipolar disorder or schizophrenia: focus on somnolenceKeming Gao
Department of Psychiatry, Bipolar Disorder Research Center at Mood Disorders Program, University Hospitals Case Medical Center Case Western Reserve University, School of Medicine, Cleveland, Ohio, USA
J Clin Psychiatry 69:302-9. 2008..This study compared the sensitivity and tolerability of antipsychotics in patients with bipolar disorder or schizophrenia... - Impact of lamotrigine and lithium on weight in obese and nonobese patients with bipolar I disorderCharles L Bowden
Department of Psychiatry, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Dr, San Antonio, TX 78229 3900, USA
Am J Psychiatry 163:1199-201. 2006..This study assessed weight changes in a large cohort of patients with bipolar disorder who were treated with randomly assigned maintenance monotherapies... - Efficacy of typical and atypical antipsychotics for primary and comorbid anxiety symptoms or disorders: a reviewKeming Gao
Department of Psychiatry, the Bipolar Disorders Research Center, University Hospitals of Cleveland Case Western Reserve University, School of Medicine, Cleveland, Ohio, USA
J Clin Psychiatry 67:1327-40. 2006..The efficacy of antipsychotics in the treatment of primary or comorbid anxiety disorders or anxiety symptoms in major depressive disorder or bipolar disorder was reviewed... - Clinical highlights in bipolar depression: focus on atypical antipsychoticsJoseph R Calabrese
University Hospitals of Cleveland Case Western Reserve University School of Medicine, Cleveland, Ohio, USA
J Clin Psychiatry 66:26-33. 2005..In addition, direct comparison of the regimens used in the current study should determine whether the differences evident between them can be confirmed... - Phenomenology of rapid-cycling bipolar disorder: data from the first 500 participants in the Systematic Treatment Enhancement ProgramChristopher D Schneck
Department of Psychiatry, University of Colorado Health Sciences Center, 4455 East 12th Ave, Box A011 15, Denver, CO 80220, USA
Am J Psychiatry 161:1902-8. 2004..This study compared demographic and phenomenological variables between bipolar patients with and without rapid cycling as a function of bipolar I versus bipolar II status... - Ziprasidone with adjunctive mood stabilizer in the maintenance treatment of bipolar I disorder: long-term changes in weight and metabolic profilesDavid E Kemp
Case Western Reserve University, University Hospitals Case Medical Center, Cleveland, OH, USA
Eur Neuropsychopharmacol 22:123-31. 2012..Our findings suggest that MetS is highly prevalent in patients with bipolar disorder, may be associated with greater manic symptom severity, and may predict treatment outcomes... - Independent predictors for lifetime and recent substance use disorders in patients with rapid-cycling bipolar disorder: focus on anxiety disordersKeming Gao
Department of Psychiatry, Bipolar Disorder Research Center at Mood Disorders Program, Case Western Reserve University School of Medicine, University Hospitals Case Medical Center, Cleveland, Ohio 44106, USA
Am J Addict 19:440-9. 2010.... - Typical and atypical antipsychotics in bipolar depressionKeming Gao
Mood Disorders Program, Department of Psychiatry, University Hospitals of Cleveland, Case Western Reserve University School of Medicine, 11400 Euclid Avenue, Cleveland, OH 44106, USA
J Clin Psychiatry 66:1376-85. 2005..Since the antipsychotic agents have been shown to diminish depressive symptoms during the treatment of mania, atypical agents are now being studied for use in bipolar depression... - Lithium treatment -- moderate dose use study (LiTMUS) for bipolar disorder: rationale and designAndrew A Nierenberg
Department of Psychiatry, Massachusetts General Hospital, Boston, MA 02114, USA
Clin Trials 6:637-48. 2009..Recent data indicate that lithium use for bipolar disorder has declined over the last decade and that lithium largely has been replaced with alternate, commercially promoted medications that may or may not result in better outcomes... - A placebo-controlled 18-month trial of lamotrigine and lithium maintenance treatment in recently depressed patients with bipolar I disorderJoseph R Calabrese
University Hospitals of Cleveland Case Western Reserve School of Medicine, Department of Psychiatry, 11400 Euclid Ave, Ste 200, Cleveland, OH 44106, USA
J Clin Psychiatry 64:1013-24. 2003..This study assessed the efficacy and tolerability of lamotrigine and lithium compared with placebo for the prevention of mood episodes in bipolar disorder... - A 20-month, double-blind, maintenance trial of lithium versus divalproex in rapid-cycling bipolar disorderJoseph R Calabrese
Case Western Reserve University, University Hospitals of Cleveland, Cleveland, OH 44106, USA
Am J Psychiatry 162:2152-61. 2005..The authors tested the hypothesis that divalproex would be more effective than lithium in the long-term management of patients with recently stabilized rapid-cycling bipolar disorder... - Relationship of open acute mania treatment to blinded maintenance outcome in bipolar I disorderSusan L McElroy
Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
J Affect Disord 107:127-33. 2008..No published studies have statistically evaluated the relationship between the outcomes in maintenance treatment and the principal acute agent... - Evaluation and comparison of psychometric instruments for pediatric bipolar spectrum disorders in four age groupsThomas W Frazier
Department of Psychiatry, University Hospitals Case Medical Center, Cleveland, OH, USA
J Child Adolesc Psychopharmacol 17:853-66. 2007..The CDRS-R may be better conceptualized as a two-factor measure in older adolescents. The semistructured K-SADS interview can be used to generate reliable diagnoses across a broad age range... - Newer treatment studies for bipolar depressionKeming Gao
NIMH Bipolar Research Center, Mood Disorders Program, University Hospitals of Cleveland Case Western Reserve University School of Medicine, Cleveland, OH, USA
Bipolar Disord 7:13-23. 2005..Depressive symptoms of bipolar disorder have more negative impact on a patient's life than manic symptoms. This review focused on the emerging efficacy data for treatments in bipolar depression... - Combination lithium and divalproex sodium in pediatric bipolar symptom re-stabilizationRobert L Findling
Department of Psychiatry, Case Western Reserve University, University Hospitals, Cleveland, OH 44106, USA
J Am Acad Child Adolesc Psychiatry 45:142-8. 2006..The primary goal of this study was to assess the rate of re-stabilization after the resumption of lithium (Li) plus divalproex (DVPX) following relapse on either agent as monotherapy... - Prefrontal hemodynamic activity predicts false memory--a near-infrared spectroscopy studyYasutaka Kubota
Mood Disorders Program, Department of Psychiatry, Case Western Reserve University University Hospitals of Cleveland, Cleveland, OH 44106, USA
Neuroimage 31:1783-9. 2006..Traces of semantic processing, reflected primarily in the left PFC activity, could eventually predict whether subjects falsely recognize non-experienced events... - A randomized, placebo-controlled, multicenter study of divalproex sodium extended release in the treatment of acute maniaCharles L Bowden
Department of Psychiatry, University of Texas Health Science Center, San Antonio 78284 7792, USA
J Clin Psychiatry 67:1501-10. 2006..The efficacy and safety of divalproex sodium extended release (divalproex ER) were evaluated in patients hospitalized for acute mania associated with bipolar I disorder, manic or mixed type (DSM-IV-TR criteria)... - Screening for bipolar disorder in a county jail at the time of criminal arrestDavid E Kemp
Department of Psychiatry, Case Western Reserve University, Cleveland, OH 44106, USA
J Psychiatr Res 42:778-86. 2008..This study assessed the operating characteristics of the mood disorder questionnaire (MDQ) among offenders arrested and detained at a county jail... - Double-blind 18-month trial of lithium versus divalproex maintenance treatment in pediatric bipolar disorderRobert L Findling
Department of Psychiatry, Case Western Reserve University, USA
J Am Acad Child Adolesc Psychiatry 44:409-17. 2005.... - Metabolic syndrome in patients enrolled in a clinical trial of aripiprazole in the maintenance treatment of bipolar I disorder: a post hoc analysis of a randomized, double-blind, placebo-controlled trialDavid E Kemp
Case Western Reserve University School of Medicine, 10524 Euclid Ave, 12th Floor, Cleveland, OH 44106, USA
J Clin Psychiatry 71:1138-44. 2010..To compare the effects of maintenance treatment with aripiprazole or placebo on the incidence of metabolic syndrome in bipolar disorder... - The Texas implementation of medication algorithms: update to the algorithms for treatment of bipolar I disorderTrisha Suppes
Department of Psychiatry, The University of Texas Southwestern Medical Center, Dallas, TX 75390 9121, USA
J Clin Psychiatry 66:870-86. 2005..The guidelines for evaluating possible medications, the criteria for selection and ranking, and the updated algorithms are described... - Double-blind, randomized, placebo-controlled long-term maintenance study of aripiprazole in children with bipolar disorderRobert L Findling
Department of Psychiatry, University Hospitals, Case Medical Center, Cleveland, OH 44106, USA
J Clin Psychiatry 73:57-63. 2012..This study evaluates the long-term efficacy of aripiprazole compared to placebo in children with bipolar disorders... - Adherence to pharmacological treatment for juvenile bipolar disorderDennis Drotar
Department of Psychiatry, Case Western Reserve University, USA
J Am Acad Child Adolesc Psychiatry 46:831-9. 2007..The objective of this study was to describe the prevalence and correlates of adherence to divalproex sodium (DVPX) and lithium carbonate (Li) combination treatment during the initial stabilization treatment phase... - A randomized, double-blind, placebo-controlled trial of quetiapine in the treatment of bipolar I or II depressionJoseph R Calabrese
University Hospitals of Cleveland and Case University School of Medicine, 11400 Euclid Ave, Suite 200, Cleveland, OH 44106, USA
Am J Psychiatry 162:1351-60. 2005..There is a major unmet need for effective options in the treatment of bipolar depression... - Recurrence in bipolar I disorder: a post hoc analysis excluding relapses in two double-blind maintenance studiesJoseph R Calabrese
Department of Psychiatry, Case Western Reserve University School of Medicine and University Hospitals of Cleveland, Cleveland, Ohio 44106, USA
Biol Psychiatry 59:1061-4. 2006..To assess the efficacy of lamotrigine or lithium in preventing mood recurrence (i.e., a new mood episode) in bipolar disorder... - Predictors of bipolar disorder risk among patients currently treated for major depressionJoseph R Calabrese
Mood Disorders Program, Department of Psychiatry, Case Western Reserve University, University Hospitals of Cleveland, Cleveland, Ohio, USA
MedGenMed 8:38. 2006..PATIENTS, DESIGN, AND SETTING: Psychiatrists from community and private practice settings sequentially selected patients with unipolar depression who exhibited nonresponse to at least 1 antidepressant (AD) trial... - Medical comorbidity in bipolar disorder: relationship between illnesses of the endocrine/metabolic system and treatment outcomeDavid E Kemp
Case Western Reserve University, University Hospitals Case Medical Center, Cleveland, OH 44106, USA
Bipolar Disord 12:404-13. 2010..It was hypothesized that illnesses of the endocrine/metabolic system would be associated with greater psychiatric symptom burden and would impact the response to treatment with lithium and valproate... - Double-blind, placebo-controlled trial of divalproex monotherapy in the treatment of symptomatic youth at high risk for developing bipolar disorderRobert L Findling
Department of Psychiatry, Case Western Reserve University, and the University Hospitals of Cleveland, Cleveland, Ohio 44106 5080, USA
J Clin Psychiatry 68:781-8. 2007..To determine if divalproex sodium was superior to placebo in the treatment of symptomatic youths who suffer from a bipolar spectrum disorder and who also have a parent with a diagnosis of a bipolar illness... - Retrospective age at onset of bipolar disorder and outcome during two-year follow-up: results from the STEP-BD studyRoy H Perlis
Bipolar Clinical and Research Program, Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, ACC 812 15 Parkman Street, Boston, MA 02114, USA
Bipolar Disord 11:391-400. 2009..Symptoms of bipolar disorder are increasingly recognized among children and adolescents, but little is known about the course of bipolar disorder among adults who experience childhood onset of symptoms... - Use of insulin sensitizers for the treatment of major depressive disorder: a pilot study of pioglitazone for major depression accompanied by abdominal obesityDavid E Kemp
Case Western Reserve University, University Hospitals Case Medical Center, Department of Psychiatry, Cleveland, OH 44106, USA
J Affect Disord 136:1164-73. 2012..This study was conducted to examine the safety and efficacy of pioglitazone, a thiazolidinedione insulin sensitizer, in adult outpatients with major depressive disorder... - Suicidal ideation and depressive symptoms among bipolar patients as predictors of the health and well-being of caregiversCheryl A Chessick
Department of Psychiatry, University of Colorado Denver School of Medicine, Denver, CO 80045, USA
Bipolar Disord 11:876-84. 2009..This study examined whether caregivers' health is associated with changes in suicidal ideation and depressive symptoms among bipolar patients observed over one year... - Maintenance efficacy of divalproex in the prevention of bipolar depressionLaszlo Gyulai
Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA
Neuropsychopharmacology 28:1374-82. 2003.... - Acute efficacy of divalproex sodium versus placebo in mood stabilizer-naive bipolar I or II depression: a double-blind, randomized, placebo-controlled trialDavid J Muzina
Department of Psychiatry and Psychology, Neurological Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA
J Clin Psychiatry 72:813-9. 2011..To conduct an exploratory evaluation of the acute efficacy of extended-release divalproex sodium compared to placebo in patients with bipolar I or II depression... - Relationship of mania symptomatology to maintenance treatment response with divalproex, lithium, or placeboCharles L Bowden
Department of Psychiatry, University of Texas Health Science Center, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA
Neuropsychopharmacology 30:1932-9. 2005..Dysphoric mania appeared to predispose patients to more side effects when treated with either divalproex or lithium during maintenance therapy... - Quetiapine for the treatment of bipolar mania in older adultsMartha Sajatovic
Department of Psychiatry, Case Western Reserve University School of Medicine, University Hospitals of Cleveland, Cleveland, OH 44106, USA
Bipolar Disord 10:662-71. 2008..The primary efficacy endpoint was the change from baseline in Young Mania Rating Scale (YMRS) total score at Day 21. A secondary endpoint was change from baseline in YMRS score at Day 84... - Does recovery from substance use disorder matter in patients with bipolar disorder?Roger D Weiss
Department of Psychiatry, Harvard Medical School, Boston, USA
J Clin Psychiatry 66:730-5; quiz 808-9. 2005..To examine the potential impact of recovery from substance use disorder (SUD) on the course of bipolar disorder among patients diagnosed with both bipolar and substance use disorders according to DSM-IV criteria... - Number needed to treat to harm for discontinuation due to adverse events in the treatment of bipolar depression, major depressive disorder, and generalized anxiety disorder with atypical antipsychoticsKeming Gao
Department of Psychiatry, Mood and Anxiety Clinic in the Mood Disorders Program, University Hospitals Case Medical Center, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA
J Clin Psychiatry 72:1063-71. 2011.... - Initiation of stimulant and antidepressant medication and clinical presentation in juvenile bipolar I disorderMaria E Pagano
Department of Psychiatry, University Hospitals of Cleveland, Case Western Reserve University School of Medicine, Cleveland, OH 44106 5080, USA
Bipolar Disord 10:334-41. 2008..Another aim was to investigate differences in clinical presentation between youths prescribed stimulant or antidepressant medication before and after the onset of juvenile BP I disorder... - Treatment-emergent mania in unipolar and bipolar depression: focus on repetitive transcranial magnetic stimulationGuohua Xia
Department of Psychiatry, Case Western Reserve University, Cleveland, OH 44106, USA
Int J Neuropsychopharmacol 11:119-30. 2008..More systematic studies are needed to better understand TEM associated with rTMS. Special precautions and measures should be adopted to prevent, monitor, and manage TEM in research and practice... - International Consensus Group on Bipolar I Depression Treatment GuidelinesJoseph R Calabrese
Department of Psychiatry, Case Western Reserve University, Cleveland, OH, USA
J Clin Psychiatry 65:571-9. 2004 - Personal and societal construction of illness among individuals with rapid-cycling bipolar disorder: a life-trajectory perspectiveMartha Sajatovic
Department of Psychiatry, Case Western Reserve University School of Medicine, Cleveland, OH, USA
Am J Geriatr Psychiatry 16:718-26. 2008..The purpose of this study was to examine the subjective experience of illness among 19 men and women with rapid cycling bipolar disorder receiving treatment at an academic psychiatry clinic... - Lamotrigine treatment of bipolar disorder: data from the first 500 patients in STEP-BDLauren B Marangell
Mood Disorders Program, Department of Psychiatry, Baylor College of Medicine, Houston, TX 77030, USA
Bipolar Disord 6:139-43. 2004..To describe the frequency and correlates of lamotrigine therapy among the first 500 patients enrolled into the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD) study... - A pilot pharmacotherapy trial for depressed youths at high genetic risk for bipolarityRobert L Findling
Department of Psychiatry, University Hospitals Case Medical Center Case Western Reserve University, Cleveland, Ohio 44106, USA
J Child Adolesc Psychopharmacol 18:615-21. 2008..As a result, future treatment studies in this population appear to be warranted, not only due to the putative impending risk of developing bipolar disorder, but also the manifest risk of current depressive episodes... - Prefrontal activation during verbal fluency tests in schizophrenia--a near-infrared spectroscopy (NIRS) studyYasutaka Kubota
Mood Disorders Program, Department of Psychiatry, Case Western Reserve University University Hospitals of Cleveland, Cleveland, OH, USA
Schizophr Res 77:65-73. 2005..The present study is the first to detect abnormal patterns of PFC activation in adults with schizophrenia in response to the distinct cognitive demands associated with letter and semantic VFT... - Maintenance treatment outcomes in older patients with bipolar I disorderMartha Sajatovic
Department of Psychiatry, Case University School of Medicine and University Hospitals of Cleveland, 11100 Euclid Avenue, Cleveland, OH 44106, USA
Am J Geriatr Psychiatry 13:305-11. 2005.... - Mood state at study entry as predictor of the polarity of relapse in bipolar disorderJoseph R Calabrese
Case University School of Medicine, University Hospitals of Cleveland, 11400 Euclid Avenue, Suite 200, Cleveland, OH 44106, USA
Biol Psychiatry 56:957-63. 2004..We conclude that putative mood stabilizers must be tested in recently manic and recently depressed patients to determine their spectrum of prophylactic efficacy... - Bipolar depression: trial-based insights to guide patient careDavid E Kemp
Case Western Reserve University, University Hospitals Case Medical Center, Cleveland, Ohio, USA
Dialogues Clin Neurosci 10:181-92. 2008..A pragmatic clinical approach is presented for management of the depressed phase of bipolar disorder... - Acute treatment of mania: an update on new medicationsPrashant Gajwani
Case School of Medicine, Mood Disorders Program, University Hospitals Case Medical Center, 11400 Euclid Avenue, Suite 200, Cleveland, OH 44106, USA
Curr Psychiatry Rep 8:504-9. 2006.... - Stability of symptoms across major depressive episodes in bipolar disorderRoy H Perlis
Bipolar Clinic and Research Program, Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
Bipolar Disord 11:867-75. 2009..These studies make the implicit assumption of stability of symptoms across episodes in mood disorders, which has rarely been investigated... - Employing parent, teacher, and youth self-report checklists in identifying pediatric bipolar spectrum disorders: an examination of diagnostic accuracy and clinical utilityShoshana Y Kahana
Case Western Reserve University, Cleveland, Ohio 44106, USA
J Child Adolesc Psychopharmacol 13:471-88. 2003..Results indicate that the Child Behavior Checklist has limited utility when attempting to derive clinically meaningful information about the presentation of juvenile BPSD... - Clinical utility of early improvement to predict response or remission in acute mania: focus on olanzapine and risperidoneDavid E Kemp
Case Western Reserve University, University Hospitals Case Medical Center, Cleveland, OH 44106, USA
J Clin Psychiatry 72:1236-41. 2011..To evaluate early improvement associated with atypical antipsychotic treatment as a predictor of later response or remission among patients experiencing an acute manic or mixed episode without psychotic features... - A placebo-controlled 18-month trial of lamotrigine and lithium maintenance treatment in recently manic or hypomanic patients with bipolar I disorderCharles L Bowden
Department of Psychiatry, University of Texas Health Science Center at San Antonio, 78229, USA
Arch Gen Psychiatry 60:392-400. 2003.... - A randomized, double-blind, placebo-controlled 26-week trial of aripiprazole in recently manic patients with bipolar I disorderPaul E Keck
Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267, USA
J Clin Psychiatry 67:626-37. 2006..To investigate the safety and efficacy of aripiprazole in preventing relapse of a mood episode in recently manic- or mixed-episode patients with bipolar I disorder stabilized on aripiprazole... - Effects of lamotrigine and lithium on body weight during maintenance treatment of bipolar I disorderGary Sachs
Department of Psychiatry, Harvard University, Harvard Bipolar Research Program, Massachusetts General Hospital, Boston, MA 02114, USA
Bipolar Disord 8:175-81. 2006.... - Combination lithium and divalproex sodium in pediatric bipolarityRobert L Findling
Department of Psychiatry, Case Western Reserve University School of Medicine, USA
J Am Acad Child Adolesc Psychiatry 42:895-901. 2003..Many youths with bipolar disorder do not respond to DVPX or Li monotherapy. An open-label study was conducted to examine the effectiveness of combination DVPX and Li therapy with youths diagnosed with bipolar disorder... - Rash in multicenter trials of lamotrigine in mood disorders: clinical relevance and managementJoseph R Calabrese
Department of Psychiatry, Case Western Reserve University University Hospitals of Cleveland, Cleveland, Ohio, USA
J Clin Psychiatry 63:1012-9. 2002..The objective of this report was to determine rash rates in clinical trials of lamotrigine in DSM-IV unipolar depression or bipolar disorder... - A comparison of the life goals program and treatment as usual for individuals with bipolar disorderMartha Sajatovic
Department of Psychiatry, Case Western Reserve University School of Medicine, 10524 Euclid Ave, Cleveland, OH 44106, USA
Psychiatr Serv 60:1182-9. 2009.... - Antipsychotic-induced extrapyramidal side effects in bipolar disorder and schizophrenia: a systematic reviewKeming Gao
Department of Psychiatry, Bipolar Disorder Research Center at the Mood Disorders Program, University Hospitals Case Medical Center Case Western Reserve University, School of Medicine, Cleveland, OH, USA
J Clin Psychopharmacol 28:203-9. 2008..This review is to compare antipsychotic-induced EPS relative to placebo in bipolar disorder (BPD) and schizophrenia... - Recent placebo-controlled acute trials in bipolar depression: focus on methodologyDavid J Muzina
Cleveland Clinic Foundation, Cleveland, Ohio, USA
Int J Neuropsychopharmacol 6:285-91. 2003..Moclobemide monotherapy was similar in efficacy to imipramine (n=156), but had a lower rate of switching (4% vs. 11%)... - Atypical antipsychotics in primary generalized anxiety disorder or comorbid with mood disordersKeming Gao
Department of Psychiatry, Mood and Anxiety Clinic in the Mood Disorders Program, Case Western Reserve University School of Medicine, University Hospitals Case Medical Center, Cleveland, OH 44106, USA
Expert Rev Neurother 9:1147-58. 2009..However, in contrast to antidepressants and benzodiazepines, the long-term risk and benefit of atypical antipsychotics in the treatment of GAD is yet to be determined... - Comparing the diagnostic accuracy of six potential screening instruments for bipolar disorder in youths aged 5 to 17 yearsEric A Youngstrom
Department of Psychology, Case Western Reserve University, University Hospitals of Cleveland, Ohia 44106 7123, USA
J Am Acad Child Adolesc Psychiatry 43:847-58. 2004..To compare the diagnostic efficiency of six index tests as predictors of juvenile bipolar disorder in two large outpatient samples, aged 5 to 10 and 11 to 17 years, gathered from 1997 to 2002... - Overview of patient care issues and treatment in bipolar spectrum and bipolar II disorderJoseph R Calabrese
Mood Disorders Program, Department of Psychiatry, Case Western Reserve University, University Hospitals of Cleveland, Ohio, USA
J Clin Psychiatry 69:e18. 2008.... - Gender differences in criminality: bipolar disorder with co-occurring substance abuseSusan Hatters Friedman
Department of Psychiatry, University Hospitals of Cleveland, Hanna Pavilion, 11100 Euclid Avenue, Cleveland, OH 44106, USA
J Am Acad Psychiatry Law 33:188-95. 2005..Implications from this pilot study include the need for earlier identification of bipolar disorder and for the increased availability of psychiatric and substance abuse services within correctional facilities... - Antiepileptic drugs in mood-disordered patientsPrashant Gajwani
NIMH Bipolar Research Center, Case Western Reserve University School of Medicine, Mood Disorders Program, University Hospitals of Cleveland, OH, USA
Epilepsia 46:38-44. 2005..LTG seems to be effective against depression and mania, with a more robust activity against depression. No firm evidence supports a role for vigabatrin, tiagabine, topiramate, or levetiracetam in these disorders... - Sex differences in pediatric bipolar disorderJeanne M Duax
Department of Psychology, Case Western Reserve University, Cleveland, OH 44106 7123, USA
J Clin Psychiatry 68:1565-73. 2007..To explore sex differences in pediatric bipolar disorder in terms of subtype and severity of depressive and manic symptomatology... - Methylphenidate in the treatment of children and adolescents with bipolar disorder and attention-deficit/hyperactivity disorderRobert L Findling
Department of Psychiatry, Case Western Reserve University, University Hospitals Case Medical Center, Cleveland, OH 44106 5080, USA
J Am Acad Child Adolesc Psychiatry 46:1445-53. 2007..To examine the short-term efficacy of methylphenidate in the treatment of youths with bipolar disorder (BD) and comorbid attention deficit/hyperactivity disorder (ADHD)... - Depression mood stabilisation: novel concepts and clinical managementJoseph R Calabrese
Case Western Reserve University, MD 11400 Euclid Avenue, Suite 200, Cleveland, OH 44106, USA
Eur Neuropsychopharmacol 14:S100-7. 2004..Lamotrigine represents a valuable addition to the current therapeutic armamentarium for bipolar disorder, allowing a therapeutic balance between the treatment of mania and depression... - Comparing diagnostic checklists for pediatric bipolar disorder in academic and community mental health settingsEric Youngstrom
Department of Psychology, Case Western Reserve University, Cleveland, OH 44106, USA
Bipolar Disord 7:507-17. 2005.... - Citalopram treatment of fluoxetine-intolerant depressed patientsJoseph R Calabrese
Mood Disorders Program, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA
J Clin Psychiatry 64:562-7. 2003..We assessed the tolerability of and response to citalopram in depressed patients who had discontinued fluoxetine treatment due to adverse events... - Priority actions to improve the care of persons with co-occurring substance abuse and other mental disorders: a call to actionDennis S Charney
Department of Psychiatry, University of Pennsylvania School of Medicine, 3900 Chestnut Street, Philadelphia, PA 19104-6178, USA
Biol Psychiatry 56:703-13. 2004 - Healthcare resource utilization in bipolar depression compared with unipolar depression: results of a United States population-based studyMark A Frye
Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA
CNS Spectr 11:704-10; quiz 719. 2006..This study examined healthcare utilization in the past year by subjects who screened positive for bipolar versus unipolar depression... - Treatment-resistant bipolar depression: a STEP-BD equipoise randomized effectiveness trial of antidepressant augmentation with lamotrigine, inositol, or risperidoneAndrew A Nierenberg
Massachusetts General Hospital Bipolar Clinic and Research Program, Suite 580, 50 Staniford Street, Boston, MA 02114, USA
Am J Psychiatry 163:210-6. 2006..This study represents the first randomized trial of competing options for treatment-resistant bipolar depression and assesses the effectiveness and safety of antidepressant augmentation with lamotrigine, inositol, and risperidone... - Screening for bipolar disorder in the communityRobert M A Hirschfeld
Department of Psychiatry and Behavioral Sciences, University of Texas Medical Branch, Galveston, 77555 188, USA
J Clin Psychiatry 64:53-9. 2003..Our goal was to estimate the rate of positive screens for bipolar I and bipolar II disorders in the general population of the United States... - Olanzapine in the acute treatment of bipolar I disorder with a history of rapid cyclingTodd M Sanger
Lilly Research Laboratories, Indianapolis, IN 46285, USA
J Affect Disord 73:155-61. 2003..CONCLUSIONS: These results indicate that olanzapine was effective in reducing symptoms of mania and well tolerated in patients with bipolar I disorder with a rapid-cycling course... - Contributors to suicidal ideation among bipolar patients with and without a history of suicide attemptsMichael H Allen
University of Colorado Health Science Center, University North Pavilion, 4455 East 12th Avenue, Denver, CO, USA
Suicide Life Threat Behav 35:671-80. 2005..Bipolar patients with suicidal ideation may benefit from different treatment strategies depending on their prior attempt status... - Randomized, placebo-controlled trial of olanzapine as maintenance therapy in patients with bipolar I disorder responding to acute treatment with olanzapineMauricio Tohen
Lilly Research Laboratories, Indianapolis, IN 46285, USA
Am J Psychiatry 163:247-56. 2006..In a placebo-controlled, double-blind study, the authors investigated the efficacy and safety of olanzapine as monotherapy in relapse prevention in bipolar I disorder... - Psychosis in mania: specificity of its role in severity and treatment responseAlan C Swann
University of Texas Medical School, Houston 77030, USA
J Clin Psychiatry 65:825-9. 2004..Psychosis is a prominent characteristic of manic episodes. We investigated relationships between the presence of psychotic features, the severity of the manic syndrome, and syndrome severity's response to treatment... - Long-term treatment of bipolar disorder with lamotrigineJoseph R Calabrese
J Clin Psychiatry 63:18-22. 2002.... - Bipolar depression: the role of atypical antipsychoticsRobert M Post
Expert Rev Neurother 4:S27-33. 2004..The receptor-binding profile of these agents supports a role in the treatment of depressive symptoms and clinical data are beginning to emerge of their efficacy in both the acute and maintenance setting... - Third generation anticonvulsants in bipolar disorder: a review of efficacy and summary of clinical recommendationsLakshmi N Yatham
Department of Psychiatry, University of British Columbia, Vancouver, Canada
J Clin Psychiatry 63:275-83. 2002..To review the literature on efficacy of third generation anticonvulsants for treatment of bipolar disorder and provide clinical recommendations... - Pattern of response to divalproex, lithium, or placebo in four naturalistic subtypes of maniaAlan C Swann
University of Texas-Houston Health Science Center, P.O. Box 20708, Houston, TX 77225, USA
Neuropsychopharmacology 26:530-6. 2002..These data suggest that there are naturalistic subtypes of manic episodes with different responses to treatment... - Stabilization of mood from below versus above baseline in bipolar disorder: a new nomenclatureTerence A Ketter
Department of Psychiatry and Behavioral Science, Stanford University School of Medicine, Calif 94305 5723, USA
J Clin Psychiatry 63:146-51. 2002..In this article, the treatment options for bipolar disorder, with a focus on depression and rapid cycling, are discussed according to this new conceptualization of management from below and above baseline... - Efficacy of olanzapine in combination with valproate or lithium in the treatment of mania in patients partially nonresponsive to valproate or lithium monotherapyMauricio Tohen
Lilly Research Laboratories, Eli Lilly and Co, Indianapolis, IN 46285, USA
Arch Gen Psychiatry 59:62-9. 2002..CONCLUSION: Compared with the use of valproate or lithium alone, the addition of olanzapine provided superior efficacy in the treatment of manic and mixed bipolar episodes... - Comparing the effects of sampling designs on the diagnostic accuracy of eight promising screening algorithms for pediatric bipolar disorderEric Youngstrom
Department of Psychology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 3270, USA
Biol Psychiatry 60:1013-9. 2006..The present investigation compared eight screening algorithms in the same sample but under two different design strategies... - Pharmacotherapy for bipolar disorder and comorbid conditions: baseline data from STEP-BDNaomi M Simon
Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
J Clin Psychopharmacol 24:512-20. 2004..Our findings highlight the need for greater clinical guidance and treatment options for patients with bipolar disorder and comorbidity...