E D Caine

Summary

Affiliation: University of Rochester
Country: USA

Publications

  1. pmc Alcohol policy, social context, and infant health: the impact of minimum legal drinking age
    Ning Zhang
    Department of Community and Preventive Medicine, University of Rochester School of Medicine, 265 Crittenden Blvd, CU 420644, Rochester, NY 14642, USA
    Int J Environ Res Public Health 8:3796-809. 2011
  2. pmc Forging an agenda for suicide prevention in the United States
    Eric D Caine
    Injury Control Research Center for Suicide Prevention, Department of Psychiatry, University of Rochester Medical Center, Rochester, NY 14642 8409, USA
    Am J Public Health 103:822-9. 2013
  3. ncbi request reprint Etiologies, environments, and genes--challenges for psychiatric diagnosis during an era of scientific transition
    Eric D Caine
    Department of Psychiatry, University of Rochester Medical Center, Rochester, NY 14642 8409, USA
    Am J Geriatr Psychiatry 15:12-6. 2007
  4. ncbi request reprint Clinical perspectives on atypical antipsychotics for treatment of agitation
    Eric D Caine
    Department of Psychiatry, University of Rochester Medical Center, Rochester, NY, USA
    J Clin Psychiatry 67:22-31. 2006
  5. ncbi request reprint Suicide in the elderly
    E D Caine
    University of Rochester Medical Center, New York 14642 8409, USA
    Int Clin Psychopharmacol 16:S25-30. 2001
  6. ncbi request reprint Medical illness burden, trait neuroticism, and depression in older primary care patients
    J M Lyness
    Department of Psychiatry, University of Rochester School of Medicine and Dentistry, NY, USA
    Am J Psychiatry 155:969-71. 1998
  7. ncbi request reprint Age and suicidal ideation in older depressed inpatients
    P R Duberstein
    Department of Psychiatry, University of Rochester Medical Center, Rochester, NY 14642 8409 Paul
    Am J Geriatr Psychiatry 7:289-96. 1999
  8. ncbi request reprint Relationships of age and axis I diagnoses in victims of completed suicide: a psychological autopsy study
    Y Conwell
    Department of Psychiatry, University of Rochester School of Medicine, NY, USA
    Am J Psychiatry 153:1001-8. 1996
  9. ncbi request reprint Cerebrovascular risk factors and depression in older primary care patients: testing a vascular brain disease model of depression
    J M Lyness
    Department of Psychiatry, University of Rochester Medical Center, NY 14642, USA
    Am J Geriatr Psychiatry 7:252-8. 1999
  10. ncbi request reprint Cerebrovascular risk factors and later-life major depression. Testing a small-vessel brain disease model
    J M Lyness
    Department of Psychiatry, University of Rochester School of Medicine and Dentistry, New York, USA
    Am J Geriatr Psychiatry 6:5-13. 1998

Detail Information

Publications56

  1. pmc Alcohol policy, social context, and infant health: the impact of minimum legal drinking age
    Ning Zhang
    Department of Community and Preventive Medicine, University of Rochester School of Medicine, 265 Crittenden Blvd, CU 420644, Rochester, NY 14642, USA
    Int J Environ Res Public Health 8:3796-809. 2011
    ..This paper explores distal (secondary) effects of changing MLDA on indices of infant health, and whether changes in drinking behaviors or birth composition contributed to these effects...
  2. pmc Forging an agenda for suicide prevention in the United States
    Eric D Caine
    Injury Control Research Center for Suicide Prevention, Department of Psychiatry, University of Rochester Medical Center, Rochester, NY 14642 8409, USA
    Am J Public Health 103:822-9. 2013
    ..We need scientific and social processes that define priorities and assess their potential for reducing what has been a steadily increasing rate of suicide during the past decade...
  3. ncbi request reprint Etiologies, environments, and genes--challenges for psychiatric diagnosis during an era of scientific transition
    Eric D Caine
    Department of Psychiatry, University of Rochester Medical Center, Rochester, NY 14642 8409, USA
    Am J Geriatr Psychiatry 15:12-6. 2007
  4. ncbi request reprint Clinical perspectives on atypical antipsychotics for treatment of agitation
    Eric D Caine
    Department of Psychiatry, University of Rochester Medical Center, Rochester, NY, USA
    J Clin Psychiatry 67:22-31. 2006
    ..For bipolar patients, these agents are valid therapeutic options for acute as well as longer-term alleviation of manic symptoms, including agitation. Safety concerns, however, limit their use in agitated elderly patients with dementia...
  5. ncbi request reprint Suicide in the elderly
    E D Caine
    University of Rochester Medical Center, New York 14642 8409, USA
    Int Clin Psychopharmacol 16:S25-30. 2001
    ....
  6. ncbi request reprint Medical illness burden, trait neuroticism, and depression in older primary care patients
    J M Lyness
    Department of Psychiatry, University of Rochester School of Medicine and Dentistry, NY, USA
    Am J Psychiatry 155:969-71. 1998
    ..The authors tested the hypotheses that medical illness burden is independently associated with depression and that this association is moderated by neuroticism...
  7. ncbi request reprint Age and suicidal ideation in older depressed inpatients
    P R Duberstein
    Department of Psychiatry, University of Rochester Medical Center, Rochester, NY 14642 8409 Paul
    Am J Geriatr Psychiatry 7:289-96. 1999
    ..Preventive or treatment measures initiated after the onset of the suicidal state may be insufficient, and other preventive strategies ought to be considered...
  8. ncbi request reprint Relationships of age and axis I diagnoses in victims of completed suicide: a psychological autopsy study
    Y Conwell
    Department of Psychiatry, University of Rochester School of Medicine, NY, USA
    Am J Psychiatry 153:1001-8. 1996
    ..Psychiatric illness is a potent risk factor for suicide, rates of which differ markedly with age. The purpose of this study was to examine whether the psychiatric diagnoses of suicide victims vary predictably with age...
  9. ncbi request reprint Cerebrovascular risk factors and depression in older primary care patients: testing a vascular brain disease model of depression
    J M Lyness
    Department of Psychiatry, University of Rochester Medical Center, NY 14642, USA
    Am J Geriatr Psychiatry 7:252-8. 1999
    ..Future work should include longitudinal study with larger sample sizes...
  10. ncbi request reprint Cerebrovascular risk factors and later-life major depression. Testing a small-vessel brain disease model
    J M Lyness
    Department of Psychiatry, University of Rochester School of Medicine and Dentistry, New York, USA
    Am J Geriatr Psychiatry 6:5-13. 1998
    ..These data did not support the notion that a linear model of small-vessel disease might apply to the great majority of older inpatients with major depression...
  11. ncbi request reprint Cerebrovascular risk factors and 1-year depression outcome in older primary care patients
    J M Lyness
    Department of Psychiatry, University of Rochester Medical Center, Rochester, NY 14642, USA
    Am J Psychiatry 157:1499-501. 2000
    ....
  12. ncbi request reprint Poor social integration and suicide: fact or artifact? A case-control study
    P R Duberstein
    Center for the Study and Prevention of Suicide, University of Rochester Medical Center, Rochester, NY 14642, USA
    Psychol Med 34:1331-7. 2004
    ..Sociological studies have shown that poor social integration confers suicide risk. It is not known whether poor integration amplifies risk after adjusting statistically for the effects of mental disorders and employment status...
  13. ncbi request reprint Age differences in behaviors leading to completed suicide
    Y Conwell
    University of Rochester School of Medicine, NY, USA
    Am J Geriatr Psychiatry 6:122-6. 1998
    ..Primary prevention should be the focus of efforts to decrease suicide rates in late life...
  14. ncbi request reprint Ruminative thinking in older inpatients with major depression
    J M Lyness
    Department of Psychiatry, University of Rochester School of Medicine and Dentistry, NY 14642, USA
    J Affect Disord 46:273-7. 1997
    ..Further investigations in inpatients and other populations examining its relationships to other phenomenology, to course and outcome, and to putative underlying mechanisms of depression are warranted...
  15. ncbi request reprint Psychological vulnerability to completed suicide: a review of empirical studies
    K R Conner
    Department of Psychiatry, Center for the Study and Prevention of Suicide, University of Rochester School of Medicine and Dentistry, NY 14642, USA
    Suicide Life Threat Behav 31:367-85. 2001
    ..Current knowledge of psychological vulnerability to completed suicide could inform social and neurobiological research, and thereby deepen understanding of suicide while potentially bridging these areas of study...
  16. ncbi request reprint Personality traits and suicidal behavior and ideation in depressed inpatients 50 years of age and older
    P R Duberstein
    University of Rochester Medical Center, New York, USA
    J Gerontol B Psychol Sci Soc Sci 55:P18-26. 2000
    ....
  17. ncbi request reprint Screening for depression in elderly primary care patients. A comparison of the Center for Epidemiologic Studies-Depression Scale and the Geriatric Depression Scale
    J M Lyness
    Department of Psychiatry, University of Rochester School of Medicine and Dentistry, NY, USA
    Arch Intern Med 157:449-54. 1997
    ..However, available findings from younger patients may not generalize to older persons, and existing studies of screening instruments in older patient samples have suffered substantial methodological limitations...
  18. ncbi request reprint Depression and self-reported functional status in older primary care patients
    P A Sinclair
    Laboratory of Depression and Medical Comorbidity, Program in Geriatrics and Neuropsychiatry, Department of Psychiatry, University of Rochester School of Medicine, NY, USA
    Am J Psychiatry 158:416-9. 2001
    ..CONCLUSIONS: Clinicians and researchers should recognize that depression can confound the self-reporting and attribution of functional disability...
  19. ncbi request reprint Stress, medical illness, and depression
    L M Slimmer
    Department of Psychiatry, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA
    Semin Clin Neuropsychiatry 6:12-26. 2001
    ..We will use the specific example of major depression occurring after acute myocardial infarction to illustrate the application of our theoretical framework...
  20. pmc Potential research participants' views regarding researcher and institutional financial conflicts of interest
    S Y H Kim
    Department of Psychiatry, University of Rochester Medical Center, Rochester, NY 14642, USA
    J Med Ethics 30:73-9. 2004
    ..While data exist on the perspectives and roles of academic institutions, investigators, industry sponsors, and scientific journals, little is known about the perspectives of potential research participants...
  21. ncbi request reprint Assessing the competence of persons with Alzheimer's disease in providing informed consent for participation in research
    S Y Kim
    Department of Psychiatry and Division of Medical Humanities, University of Rochester School of Medicine and Dentistry, NY 14642, USA
    Am J Psychiatry 158:712-7. 2001
    ..A criterion validation study was carried out to help address this question...
  22. ncbi request reprint Considering the role of the amygdala in psychotic illness: a clinicopathological correlation
    J L Fudge
    Department of Psychiatry, University of Rochester Medical Center, New York 14642, USA
    J Neuropsychiatry Clin Neurosci 10:383-94. 1998
    ..They use this case to review what is known of the functional anatomy of the amygdala and its possible role in some psychoses...
  23. ncbi request reprint Depression, medical illness, and interleukin-1beta in older cardiac patients
    J M Lyness
    Department of Psychiatry, University of Rochester Medical Center, New York 14642, USA
    Int J Psychiatry Med 31:305-10. 2001
    ..We collected pilot data to test the hypothesis that interleukin-1beta (IL-1beta) is associated with depression in a cardiac patient group...
  24. ncbi request reprint Suicide at 50 years of age and older: perceived physical illness, family discord and financial strain
    P R Duberstein
    Center for the Study and Prevention of Suicide, University of Rochester Medical Center, Rochester, NY 14642, USA
    Psychol Med 34:137-46. 2004
    ..Mental disorders amplify suicide risk across the lifecourse, but most people with mental disorder do not take their own lives. Few controlled studies have examined the contribution of stressors to suicide risk...
  25. doi request reprint Predicting self- and other-directed violence among discharged psychiatric patients: the roles of anger and psychopathic traits
    M T Swogger
    Department of Psychiatry, University of Rochester Medical Center, Rochester, NY, USA
    Psychol Med 42:371-9. 2012
    ..We examined the extent to which trait anger and psychopathic traits predicted post-discharge self-directed violence (SDV) and other-directed violence (ODV) among psychiatric patients...
  26. pmc Psychiatric disorders in older primary care patients
    J M Lyness
    Program in Geriatrics and Neuropsychiatry, Department of Psychiatry, University of Rochester School of Medicine, Rochester, NY, USA
    J Gen Intern Med 14:249-54. 1999
    ..Clinicians should be particularly vigilant about depression when evaluating older patients with anxiety or putative somatoform symptoms, given the relatively low prevalences of primary anxiety and somatoform disorders...
  27. pmc Establishing priorities for reducing suicide and its antecedents in the United States
    Kerry L Knox
    University of Rochester School of Medicine, Department of Community and Preventive Medicine, 601 Elmwood Ave, Box 644, Rochester, NY 14620, USA
    Am J Public Health 95:1898-903. 2005
    ..Men in the middle years of life contribute disproportionately to the public health burden because of completed suicide. The substantial burden evident in this group has not translated into a public health priority...
  28. ncbi request reprint Cerebrovascular risk factors, executive dysfunction, and depression in older primary care patients
    Michelle L Schoepflin Sanders
    Program in Geriatrics and Neuropsychiatry, Department of Psychiatry, University of Rochester Medical Center, Rochester, New York 14642, USA
    Am J Geriatr Psychiatry 14:145-52. 2006
    ..This study examined the associations of selected components of executive function with cerebrovascular risk factors, depression, and overall functional status...
  29. ncbi request reprint Determining when impairment constitutes incapacity for informed consent in schizophrenia research
    Scott Y H Kim
    Department of Psychiatry, Bioethics Program, and Center for Behavioral and Decision Sciences in Medicine, University of Michigan, 300 North Ingalls, Ann Arbor, MI 48109 0429, and Massachusetts General Hospital, Boston, USA
    Br J Psychiatry 191:38-43. 2007
    ..Although people with schizophrenia display impaired abilities for consent, it is not known how much impairment constitutes incapacity...
  30. ncbi request reprint The relationship of medical comorbidity and depression in older, primary care patients
    Jeffrey M Lyness
    Program in Geriatrics and Neuropsychiatry, Department of Psychiatry, University of Rochester Medical Center, 300 Crittenden Blvd, Rochester, NY 14642, USA
    Psychosomatics 47:435-9. 2006
    ..This generates the hypothesis that, in general primary care populations, the relationship of medical illness to depression may be multimodal and/or may involve shared pathobiological or psychosocial mechanisms...
  31. doi request reprint Psychosocial and clinical correlates of suicidal acts: results from a national population survey
    Emma Robertson Blackmore
    Department of Psychiatry, University of Rochester Medical Centre, Rochester, NY 14642 8409, USA
    Br J Psychiatry 192:279-84. 2008
    ..Clinical samples have identified a number of psychosocial risk factors for suicidal acts but it is unclear if these findings relate to the general population...
  32. ncbi request reprint Does depression precede or follow executive dysfunction? Outcomes in older primary care patients
    Xingjia Cui
    Geriatrics Psychiatry program, Department of Psychiatry, University of Rochester Medical Center, Rochester, NY 14642, USA
    Am J Psychiatry 164:1221-8. 2007
    ..The authors sought to test the potentially reciprocal relationships between depression and executive dysfunction in older patients over time...
  33. ncbi request reprint The clinical significance of subsyndromal depression in older primary care patients
    Jeffrey M Lyness
    Department of Psychiatry, University of Rochester Medical Center, Rochester, NY 14642, USA
    Am J Geriatr Psychiatry 15:214-23. 2007
    ....
  34. ncbi request reprint Screening as an approach for adolescent suicide prevention
    Juan B Pena
    Center for the Study and Prevention of Suicide, Dept of Psychiatry, University of Rochester Medical Center, New York 14642, USA
    Suicide Life Threat Behav 36:614-37. 2006
    ....
  35. ncbi request reprint Inflammatory markers, depression, and cardiac disease
    Jeffrey M Lyness
    Am J Psychiatry 162:195; author reply 195. 2005
  36. ncbi request reprint Association of alcohol and drug use disorders and completed suicide: an empirical review of cohort studies
    Holly C Wilcox
    Department of Psychiatry and Behavioral Sciences, Center for Family Research, George Washington University, Washington DC 20037, USA
    Drug Alcohol Depend 76:S11-9. 2004
    ..C., Barraclough, B., 1997. Suicide as an outcome for mental disorders. A meta-analysis, Br. J. Psychiatry 170, 205-228] of retrospective and prospective cohort studies of alcohol and drug use disorders and suicide...
  37. ncbi request reprint Risk factors for suicide in later life
    Yeates Conwell
    University of Rochester School of Medicine, Department of Psychiatry and Center for the Study and Prevention of Suicide, Rochester, New York 14642, USA
    Biol Psychiatry 52:193-204. 2002
    ..Additional research is needed to define more precisely the interactions between emotional, physical, and social factors that determine risk for suicide in the older adult...
  38. ncbi request reprint Access to firearms and risk for suicide in middle-aged and older adults
    Yeates Conwell
    Department of Psychiatry, University of Rochester School of Medicine, NY 14642 8409, USA
    Am J Geriatr Psychiatry 10:407-16. 2002
    ..Education programs for older persons, their families, and healthcare providers concerning the risks of having a gun in the home and reinforcement of rules for safe storage may contribute to reducing the rate of suicide in older people...
  39. ncbi request reprint Impaired decision-making ability in subjects with Alzheimer's disease and willingness to participate in research
    Scott Y H Kim
    Department of Psychiatry, University of Rochester School of Medicne and Dentistry, NY 14642, USA
    Am J Psychiatry 159:797-802. 2002
    ..The authors examined the effects of cognitive and decisional impairment on willingness to participate in research among persons with Alzheimer's disease...
  40. ncbi request reprint Current state of research on decision-making competence of cognitively impaired elderly persons
    Scott Y H Kim
    Department of Psychiatry, Division of Medical Humanities, University of Rochester School of Medicine, NY 14642, USA
    Am J Geriatr Psychiatry 10:151-65. 2002
    ..It is beginning to yield findings with practical implications for preserving the autonomy and welfare of this group of vulnerable elderly patients...
  41. ncbi request reprint Utility and limits of the mini mental state examination in evaluating consent capacity in Alzheimer's disease
    Scott Y H Kim
    Department of Psychiatry, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Psychiatr Serv 53:1322-4. 2002
    ..Nevertheless, there may still be approaches that enhance the practical utility of the MMSE in capacity assessment...
  42. ncbi request reprint Personality is associated with perceived health and functional status in older primary care patients
    Paul R Duberstein
    Department of Psychiatry and The Cancer Center, University of Rochester Medical Center, New York 14642, USA
    Psychol Aging 18:25-37. 2003
    ..This study underscores the conceptual and heuristic value of examining moderators of the links between personality variables and health...
  43. pmc Risk of suicide and related adverse outcomes after exposure to a suicide prevention programme in the US Air Force: cohort study
    Kerry L Knox
    University of Rochester Center for the Study and Prevention of Suicide, University of Rochester Medical Center, Rochester, NY 14642, USA
    BMJ 327:1376. 2003
    ..To evaluate the impact of the US Air Force suicide prevention programme on risk of suicide and other outcomes that share underlying risk factors...
  44. pmc If suicide is a public health problem, what are we doing to prevent it?
    Kerry L Knox
    Department of Community and Preventive Medicine, University of Rochester, Rochester, NY 14642, USA
    Am J Public Health 94:37-45. 2004
    ..We examined whether the current urgency to develop effective interventions for suicide prevention can benefit from an understanding of the evolution of population-based strategies to prevent heart disease...
  45. ncbi request reprint Self-rated health, depression, and one-year health outcomes in older primary care patients
    Jeffrey M Lyness
    Department of Psychiatry, University of Rochester Medical Center, 300 Crittenden Boulevard, Rochester, NY 14642, USA
    Am J Geriatr Psychiatry 12:110-3. 2004
    ..The authors tested the hypothesis that poorer self-rated health is associated with poorer health outcomes...
  46. ncbi request reprint Suicide among women: a critical review
    Linda H Chaudron
    Center for the Study and Prevention of Suicide, Department of Psychiatry, University of Rochester School of Medicine, USA
    J Am Med Womens Assoc 59:125-34. 2004
    ....
  47. ncbi request reprint Opportunities of life: preventing suicide in elderly patients
    Eve K Moscicki
    Arch Intern Med 164:1171-2. 2004
  48. ncbi request reprint Depressive disorders and symptoms in older primary care patients: one-year outcomes
    Jeffrey M Lyness
    Laboratory of Depression and Medical Comorbidity, Program in Geriatrics and Neuropsychiatry, University of Rochester Medical Center, Rochester, NY 14642, USA
    Am J Geriatr Psychiatry 10:275-82. 2002
    ..Depressive conditions had considerable rates of persistence, yet the outcome was not uniformly poor. Longer-term naturalistic study is needed, as are treatment studies targeting those at highest risk of recurrence or chronicity...
  49. ncbi request reprint Provisional diagnostic criteria for depression of Alzheimer disease
    Jason T Olin
    Adult and Geriatric Treatment and Preventive Interventions Research Branch, National Institute of Mental Health, Bethesda, MD 20892 9635, USA
    Am J Geriatr Psychiatry 10:125-8. 2002
    ....
  50. pmc Increase in US youth suicide rates 2004
    Robert M Bossarte
    Department of Community Medicine, West Virginia University, Morgantown, WV 26506, USA
    Inj Prev 14:2-3. 2008
  51. ncbi request reprint Threatened and attempted suicide by partner-violent male respondents petitioned to family violence court
    Kenneth R Conner
    University of Rochester Medical Center, The State University of New York at Buffalo, School of Law Family Violence Clinic, NY 14642, USA
    Violence Vict 17:115-25. 2002
    ..The study of suicidal behavior in partner-violent men may inform the prevention of suicide and severe domestic violence...
  52. ncbi request reprint Mortality in people with schizophrenia in rural China: 10-year cohort study
    Mao Sheng Ran
    College of Professional Studies, University of Guam, Mangilao, Guam 96923, USA
    Br J Psychiatry 190:237-42. 2007
    ..Long-term mortality and the risk factors for premature death among patients with schizophrenia living in rural communities are unknown...
  53. ncbi request reprint Overview of workshop on drug abuse and suicidal behavior
    Lynda Erinoff
    Drug Alcohol Depend 76:S3-9. 2004
  54. ncbi request reprint Multiple sclerosis, depression, and the risk of suicide
    Eric D Caine
    Neurology 59:662-3. 2002
  55. ncbi request reprint Do clinicians follow a risk-sensitive model of capacity-determination? An experimental video survey
    Scott Y H Kim
    Dept of Psychiatry, the Bioethics Program, and the Center for Behavioral and Decision Sciences in Medicine, Univ of Michigan, MI, USA
    Psychosomatics 47:325-9. 2006
    ..Thus, clinicians, in fact, use the normative risk-sensitive model for capacity, but there remains considerable unexplained variability in their judgments...
  56. ncbi request reprint Strategies to prevent suicide
    Kerry L Knox
    JAMA 295:1515-6; author reply 1516. 2006

Research Grants6

  1. PREVENTING SUICIDE--A SCIENTIFIC CONSENSUS PROCESS
    Eric Caine; Fiscal Year: 2005
    ..abstract_text> ..
  2. NIMH INSTITUTIONAL NATIONAL RESEARCH SERVICE AWARD
    Eric Caine; Fiscal Year: 2007
    ..Formal didactic courses are selected to meet the specific needs of each trainee, and there are a wide array of seminars and research meetings to complement the informal interactions that abound in our centers and laboratories. ..
  3. Suicide Research and Prevention MHREG
    Eric Caine; Fiscal Year: 2007
    ..The SPR/MHREG provides a mechanism for efficient sharing and broader dissemination of the mentoring and research expertise that we have developed. ..
  4. Center for Public Health and Population Interventions for Preventing Suicide
    Eric Caine; Fiscal Year: 2007
    ..abstract_text> ..