LAWRENCE CAHILL

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Sex- and hemisphere-related influences on the neurobiology of emotionally influenced memory
    Larry Cahill
    Qureshey Lab, Center for the Neurobiology of Learning and Memory, Irvine, CA 92697, USA
    Prog Neuropsychopharmacol Biol Psychiatry 27:1235-41. 2003
  2. ncbi request reprint Why sex matters for neuroscience
    Larry Cahill
    Center for the Neurobiology of Learning and Memory, Qureshey Laboratory, Department of Neurobiology and Behaviour, University of California, Irvine, California 92697 3800, USA
    Nat Rev Neurosci 7:477-84. 2006
  3. pmc A half-truth is a whole lie: on the necessity of investigating sex influences on the brain
    Larry Cahill
    Department of Neurobiology and Behavior, University of California, Irvine, California 92697 3800, USA
    Endocrinology 153:2541-3. 2012
  4. doi request reprint Sex influences on brain and emotional memory: the burden of proof has shifted
    Larry Cahill
    Department of Neurobiology and Behavior, Center for the Neurobiology of Learning and Memory, University of California, Irvine, CA, USA
    Prog Brain Res 186:29-40. 2010
  5. ncbi request reprint The basolateral amygdala complex is involved with, but is not necessary for, rapid acquisition of Pavlovian 'fear conditioning'
    L Cahill
    Department of Neurobiology and Behaviour and Center for the Neurobiology of Learning and Memory, University of California, Irvine, CA 92697 3800, USA
    Eur J Neurosci 12:3044-50. 2000
  6. ncbi request reprint The influence of sex versus sex-related traits on long-term memory for gist and detail from an emotional story
    Larry Cahill
    Department of Neurobiology and Behavior, Center for the Neurobiology of Learning and Memory, University of California, Irvine, CA, USA
    Conscious Cogn 13:391-400. 2004
  7. pmc Similar neural mechanisms for emotion-induced memory impairment and enhancement
    Larry Cahill
    Center for the Neurobiology of Learning and Memory, Department of Neurobiology and Behavior, University of California, Irvine, CA 92697 3800, USA
    Proc Natl Acad Sci U S A 100:13123-4. 2003
  8. ncbi request reprint Sex-related influences on the neurobiology of emotionally influenced memory
    Larry Cahill
    Center for the Neurobiology of Learning and Memory, University of California, Irvine, Irvine, California 92697 3800, USA
    Ann N Y Acad Sci 985:163-73. 2003
  9. ncbi request reprint Sex-related difference in amygdala activity during emotionally influenced memory storage
    L Cahill
    Department of Neurobiology and Behavior, Center for the Neurobiology of Learning and Memory, CA 92697 3800, USA
    Neurobiol Learn Mem 75:1-9. 2001
  10. ncbi request reprint Epinephrine enhancement of human memory consolidation: interaction with arousal at encoding
    Larry Cahill
    Department of Neurobiology and Behavior, Center for the Neurobiology of Learning and Memory, University of California at Irvine, Irvine, CA 92697 3800, USA
    Neurobiol Learn Mem 79:194-8. 2003

Research Grants

  1. Investigation of Dopamine Function In Human Amygdala
    LAWRENCE CAHILL; Fiscal Year: 2004
  2. Neural Mechanisms of Emotional Memory Consolidation
    LAWRENCE CAHILL; Fiscal Year: 2007
  3. Neural Mechanisms of Emotional Memory Consolidation
    LAWRENCE F CAHILL; Fiscal Year: 2010

Detail Information

Publications27

  1. ncbi request reprint Sex- and hemisphere-related influences on the neurobiology of emotionally influenced memory
    Larry Cahill
    Qureshey Lab, Center for the Neurobiology of Learning and Memory, Irvine, CA 92697, USA
    Prog Neuropsychopharmacol Biol Psychiatry 27:1235-41. 2003
    ..More generally, these findings presented here suggest that the interacting influences of sex and cerebral hemisphere on emotionally influenced memory are more pronounced than has been widely appreciated to date...
  2. ncbi request reprint Why sex matters for neuroscience
    Larry Cahill
    Center for the Neurobiology of Learning and Memory, Qureshey Laboratory, Department of Neurobiology and Behaviour, University of California, Irvine, California 92697 3800, USA
    Nat Rev Neurosci 7:477-84. 2006
    ..The striking quantity and diversity of sex-related influences on brain function indicate that the still widespread assumption that sex influences are negligible cannot be justified, and probably retards progress in our field...
  3. pmc A half-truth is a whole lie: on the necessity of investigating sex influences on the brain
    Larry Cahill
    Department of Neurobiology and Behavior, University of California, Irvine, California 92697 3800, USA
    Endocrinology 153:2541-3. 2012
    ....
  4. doi request reprint Sex influences on brain and emotional memory: the burden of proof has shifted
    Larry Cahill
    Department of Neurobiology and Behavior, Center for the Neurobiology of Learning and Memory, University of California, Irvine, CA, USA
    Prog Brain Res 186:29-40. 2010
    ....
  5. ncbi request reprint The basolateral amygdala complex is involved with, but is not necessary for, rapid acquisition of Pavlovian 'fear conditioning'
    L Cahill
    Department of Neurobiology and Behaviour and Center for the Neurobiology of Learning and Memory, University of California, Irvine, CA 92697 3800, USA
    Eur J Neurosci 12:3044-50. 2000
    ....
  6. ncbi request reprint The influence of sex versus sex-related traits on long-term memory for gist and detail from an emotional story
    Larry Cahill
    Department of Neurobiology and Behavior, Center for the Neurobiology of Learning and Memory, University of California, Irvine, CA, USA
    Conscious Cogn 13:391-400. 2004
    ..These findings confirm the existence of sex-related influences in the recall of emotional information, and suggest that sex-related traits, rather than actual sex per se, may be a more sensitive indicator of these influences...
  7. pmc Similar neural mechanisms for emotion-induced memory impairment and enhancement
    Larry Cahill
    Center for the Neurobiology of Learning and Memory, Department of Neurobiology and Behavior, University of California, Irvine, CA 92697 3800, USA
    Proc Natl Acad Sci U S A 100:13123-4. 2003
  8. ncbi request reprint Sex-related influences on the neurobiology of emotionally influenced memory
    Larry Cahill
    Center for the Neurobiology of Learning and Memory, University of California, Irvine, Irvine, California 92697 3800, USA
    Ann N Y Acad Sci 985:163-73. 2003
    ..The more general conclusion that we draw from these investigations is that theories of the neurobiology of emotion and memory must begin to account for the seemingly substantial influences of sex...
  9. ncbi request reprint Sex-related difference in amygdala activity during emotionally influenced memory storage
    L Cahill
    Department of Neurobiology and Behavior, Center for the Neurobiology of Learning and Memory, CA 92697 3800, USA
    Neurobiol Learn Mem 75:1-9. 2001
    ....
  10. ncbi request reprint Epinephrine enhancement of human memory consolidation: interaction with arousal at encoding
    Larry Cahill
    Department of Neurobiology and Behavior, Center for the Neurobiology of Learning and Memory, University of California at Irvine, Irvine, CA 92697 3800, USA
    Neurobiol Learn Mem 79:194-8. 2003
    ..Additionally, they suggest that in humans these hormones may interact with the degree of arousal at initial encoding of information to modulate memory consolidation processes for that information...
  11. ncbi request reprint Impaired memory consolidation in rats produced with beta-adrenergic blockade
    L Cahill
    Department of Neurobiology and Behavior, and Center for the Neurobiology of Learning and Memory, University of California, Irvine, California, 92697 3800, USA
    Neurobiol Learn Mem 74:259-66. 2000
    ....
  12. ncbi request reprint Sex-related impairment of memory for emotional events with beta-adrenergic blockade
    Larry Cahill
    Department of Neurobiology and Behavior, Center for the Neurobiology of Learning and Memory, University of California, Irvine, CA 92697 3800, USA
    Neurobiol Learn Mem 79:81-8. 2003
    ....
  13. ncbi request reprint The neurobiology of learning and memory: some reminders to remember
    L Cahill
    Center for the Neurobiology of Learning and Memory and Department of Neurobiology and Behavior, Qureshey Research Laboratory, University of California, Irvine, CA 92697 3800, USA
    Trends Neurosci 24:578-81. 2001
    ..Examples in which the lessons of history are, and are not, educating current research are also given...
  14. pmc Sex-related hemispheric lateralization of amygdala function in emotionally influenced memory: an FMRI investigation
    Larry Cahill
    Center for the Neurobiology of Learning and Memory and Department of Neurobiology and Behavior, University of California, Irvine, California, 92697 3800, USA
    Learn Mem 11:261-6. 2004
    ..Furthermore, they underscore the view that investigations of neural mechanisms underlying emotionally influenced memory must anticipate, and begin to account for, the apparently substantial influence of sex...
  15. ncbi request reprint His brain, her brain
    Larry Cahill
    University of California, Irvine, USA
    Sci Am 292:40-7. 2005
    ..It turns out that male and female brains differ quite a bit in architecture and activity. Research into these variations could lead to sex-specific treatments for disorders such as depression and schizophrenia..
  16. ncbi request reprint Amygdala modulation of parahippocampal and frontal regions during emotionally influenced memory storage
    Lisa Kilpatrick
    Department of Neurobiology and Behavior and Center for the Neurobiology of Learning and Memory, University of California, Irvine, CA 92697 3800, USA
    Neuroimage 20:2091-9. 2003
    ..These findings support the view that increased influences from the amygdala, presumably reflecting its memory-modulation function, occur during emotionally arousing learning situations...
  17. doi request reprint The role of cortisol reactivity in children's and adults' memory of a prior stressful experience
    Jodi A Quas
    Department of Psychology and Social Behavior, University of California, 4201 Social and Behavioral Sciences Gateway, Irvine, CA 92697 7085, USA
    Dev Psychobiol 53:166-74. 2011
    ..Findings also demonstrate that positive associations between cortisol reactivity and memory are evident when the event that actually elicited that reactivity serves as the to-be-remembered event...
  18. doi request reprint Children's and adults' salivary cortisol responses to an identical psychosocial laboratory stressor
    Ilona S Yim
    Department of Psychology and Social Behavior, University of California, 3340 Social Ecology II, Irvine, CA 92697 7085, USA
    Psychoneuroendocrinology 35:241-8. 2010
    ..It also suggests comparable responses in cortisol and self-reported affect in young adults and children...
  19. doi request reprint Endogenous noradrenergic activation and memory for emotional material in men and women
    Sabrina K Segal
    200 Bonney Research Labs, Center for the Neurobiology of Learning and Memory, Department of Neurobiology and Behavior, University of California, Irvine, CA 92697, USA
    Psychoneuroendocrinology 34:1263-71. 2009
    ..These findings are the first involving human subjects to indicate that the degree of endogenous noradrenergic activation in response to emotionally arousing stimuli predicts the strength of long-term memory for those stimuli...
  20. pmc Post-event spontaneous intrusive recollections and strength of memory for emotional events in men and women
    Nikole K Ferree
    200 Bonney Research Laboratory, Center for the Neurobiology of Learning and Memory, University of California, Irvine, Irvine, CA 92697, United States
    Conscious Cogn 18:126-34. 2009
    ..Additional evidence of menstrual cycle influences on SIR incidence in female participants appears to merit consideration in future work...
  21. doi request reprint Menstrual cycle modulation of the relationship between cortisol and long-term memory
    Joseph M Andreano
    200 Bonney Research Labs, Center for the Neurobiology of Learning and Memory, Department of Neurobiology and Behavior, University of California, Irvine, CA 92697, USA
    Psychoneuroendocrinology 33:874-82. 2008
    ..In addition, cortisol levels were found to be elevated during the mid-luteal phase. These findings suggest that glucocorticoid effects on memory are modulated by sex hormone levels...
  22. pmc Neuroimaging analysis of an anesthetic gas that blocks human emotional memory
    Michael T Alkire
    Department of Anesthesiology, University of California at Irvine, Orange, CA 92868, USA
    Proc Natl Acad Sci U S A 105:1722-7. 2008
    ..Collectively, the findings support the hypothesis that the amygdala mediates memory modulation by demonstrating that suppressed amygdala effectiveness equates with a loss of emotional memory...
  23. ncbi request reprint Glucocorticoid release and memory consolidation in men and women
    Joseph M Andreano
    200 Bonney Research Laboratory, Center for the Neurobiology of Learning and Memory, Department of Neurobiology and Behavior, University of California, Irvine, CA 92697, USA
    Psychol Sci 17:466-70. 2006
    ..Thus, these findings represent the first demonstration of an inverted-U relationship between activity of endogenous stress hormones and human memory...
  24. pmc Enhanced human memory consolidation with post-learning stress: interaction with the degree of arousal at encoding
    Larry Cahill
    Department of Neurobiology and Behavior, University of California, Irvine, California 92697 3800, USA
    Learn Mem 10:270-4. 2003
    ..These findings further support the view that post-learning stress hormone-related activity interacts with arousal at initial encoding to modulate memory consolidation...
  25. doi request reprint Sex influences on the neurobiology of learning and memory
    Joseph M Andreano
    Center for the Neurobiology of Learning and Memory, Department of Neurobiology and Behavior, University of California, Irvine, CA 92697 3800, USA
    Learn Mem 16:248-66. 2009
    ..We further suggest that for some tasks, stress evokes sex differences, which are not normally observed, and that these differences are mediated largely by interactions between stress and sex hormones...
  26. ncbi request reprint A case of unusual autobiographical remembering
    Elizabeth S Parker
    Department of Neurology, University of California, Los Angeles, Irvine, USA
    Neurocase 12:35-49. 2006
    ..We propose the name hyperthymestic syndrome, from the Greek word thymesis meaning remembering, and that AJ is the first reported case...
  27. ncbi request reprint Modulation of memory consolidation for olfactory learning by reversible inactivation of the basolateral amygdala
    Lisa Kilpatrick
    Department of Neurobiology and Behavior, Center for the Neurobiology of Learning and Memory, University of California, Irvine 92697 3800, USA
    Behav Neurosci 117:184-8. 2003
    ..Thus, these findings strengthen the view that the BLA plays a general role in modulation of memory storage for emotionally arousing events...

Research Grants7

  1. Investigation of Dopamine Function In Human Amygdala
    LAWRENCE CAHILL; Fiscal Year: 2004
    ..The data derived from these preliminary experiments should lay the foundation for a research program aimed at understanding how DA mechanisms within the human amygdala subserve both emotional memory and addiction. ..
  2. Neural Mechanisms of Emotional Memory Consolidation
    LAWRENCE CAHILL; Fiscal Year: 2007
    ..abstract_text> ..
  3. Neural Mechanisms of Emotional Memory Consolidation
    LAWRENCE F CAHILL; Fiscal Year: 2010
    ..Our research involving sex/stress hormone interactions in memory will also help us understand, and treat, the severe memory deficits commonly experienced in cancer patients who are deprived of sex hormones as part of their therapy. ..