Research Topics
| John CacioppoSummaryAffiliation: University of Chicago Country: USA Publications
Research Grants
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Detail Information
Publications
Social regulation of gene expression in human leukocytesSteve W Cole
Department of Medicine, Division of Hematology Oncology, UCLA School of Medicine, Los Angeles, CA 90095 1678, USA
Genome Biol 8:R189. 2007....
Lonely traits and concomitant physiological processes: the MacArthur social neuroscience studiesJ T Cacioppo
Department of Psychology, University of Chicago, 5848 S University Avenue, Chicago, IL 60637, USA
Int J Psychophysiol 35:143-54. 2000..An experimental manipulation of loneliness further suggested that the way in which people construe their self in relation to others around them has powerful effects on their self concept and, possibly, on their physiology...- In the eye of the beholder: individual differences in perceived social isolation predict regional brain activation to social stimuliJohn T Cacioppo
University of Chicago, Chicago, IL 60637, USA
J Cogn Neurosci 21:83-92. 2009.... - Scientific symbiosis represents the mutual benefit of iteratively adopting the perspective of realism and instrumentalismJohn T Cacioppo
Department of Psychology, University of Chicago, Chicago, IL 60637, USA
Am Psychol 60:347-8. 2005 - Just because you're imaging the brain doesn't mean you can stop using your head: a primer and set of first principlesJohn T Cacioppo
Department of Psychology, University of Chicago, Chicago, IL 60637, USA
J Pers Soc Psychol 85:650-61. 2003..social psychologists bring important theoretical, methodological, and statistical expertise to this interdisciplinary enterprise... - Social isolation and health, with an emphasis on underlying mechanismsJohn T Cacioppo
Department of Psychology, University of Chicago, 5848 South University Avenue, Chicago, IL 60637, USA
Perspect Biol Med 46:S39-52. 2003..We advocate a national health care plan that promotes preventive medicine, recognizes the significance of stress-related disorders, and supports the maintenance of social connections across the life span... - Feelings and emotions: roles for electrophysiological markersJohn T Cacioppo
Department of Psychology, University of Chicago, 5848 S University Avenue, Chicago, IL 60637, USA
Biol Psychol 67:235-43. 2004.... - Loneliness as a specific risk factor for depressive symptoms: cross-sectional and longitudinal analysesJohn T Cacioppo
Center for Cognitive and Social Neuroscience, University of Chicago, 5848 South University Avenue, Chicago, IL 60637, USA
Psychol Aging 21:140-51. 2006..These data suggest that loneliness and depressive symptomatology can act in a synergistic effect to diminish well-being in middle-aged and older adults... - Realism, instrumentalism, and scientific symbiosis: psychological theory as a search for truth and the discovery of solutionsJohn T Cacioppo
Department of Psychology, University of Chicago, Chicago, IL, US
Am Psychol 59:214-23. 2004.... - Common sense, intuition, and theory in personality and social psychologyJohn T Cacioppo
Department of Psychology, University of Chicago, IL 60637, USA
Pers Soc Psychol Rev 8:114-22. 2004..Refined scientific intuitions are also subject to error, however, so means of minimizing these errors are also discussed... - Component processes underlying choiceJohn T Cacioppo
Department of Psychology, University of Chicago, Chicago, IL 60637, USA
Proc Natl Acad Sci U S A 100:3016-7. 2003 - Social isolationJohn T Cacioppo
Center for Cognitive and Social Neuroscience, University of Chicago, Illinois, USA
Ann N Y Acad Sci 1231:17-22. 2011..Together, these effects contribute to higher rates of morbidity and mortality in older adults... - Social neuroscience: understanding the pieces fosters understanding the whole and vice versaJohn T Cacioppo
University of Chicago, USA
Am Psychol 57:819-31. 2002..This research underscores the unity of psychology and the importance of retaining multilevel integrative research that spans molar and molecular levels of analysis... - Multilevel integrative analyses of human behavior: social neuroscience and the complementing nature of social and biological approachesJ T Cacioppo
Department of Psychology, University of Chicago, Illinois 60637, USA
Psychol Bull 126:829-43. 2000..Especially needed in the coming years is more research on the mechanisms linking social and biological events and processes... - Alone in the crowd: the structure and spread of loneliness in a large social networkJohn T Cacioppo
Department of Psychology, University of Chicago, Chicago, IL 60637, USA
J Pers Soc Psychol 97:977-91. 2009.... - Loneliness and health: potential mechanismsJohn T Cacioppo
Department of Psychology, University of Chicago, Chicago, IL 60637, USA
Psychosom Med 64:407-17. 2002..Two studies using cross-sectional designs explored four possible mechanisms by which loneliness may have deleterious effects on health: health behaviors, cardiovascular activation, cortisol levels, and sleep... - Social neuroscience: challenges and opportunities in the study of complex behaviorJohn T Cacioppo
Center for Cognitive and Social Neuroscience, University of Chicago, 5848 S University Avenue, Chicago, IL 60637, USA
Ann N Y Acad Sci 1224:162-73. 2011..Examples of how social neuroscience is contributing to our understanding of the functions of the brain and nervous system are described, and societal implications of social neuroscience are considered... 
Social resilience: the value of social fitness with an application to the militaryJohn T Cacioppo
Department of Psychology, University of Chicago, IL 60637 1515, USA
Am Psychol 66:43-51. 2011..S. Army. Data from this program should provide valuable evidence regarding the challenge of building social resilience...- Do lonely days invade the nights? Potential social modulation of sleep efficiencyJohn T Cacioppo
Department of Psychology, University of Chicago, IL 60637, USA
Psychol Sci 13:384-7. 2002..These results also raise the possibility that social factors such as loneliness not only may influence the selection of health behaviors but also may modulate the salubrity of restorative behaviors... - Perceived social isolation makes me sad: 5-year cross-lagged analyses of loneliness and depressive symptomatology in the Chicago Health, Aging, and Social Relations StudyJohn T Cacioppo
Center for Cognitive and Social Neuroscience, University of Chicago, IL 60637, USA
Psychol Aging 25:453-63. 2010..The importance of distinguishing between loneliness and depressive symptoms and the implications for loneliness and depressive symptomatology in older adults are discussed... - Cardiac autonomic balance versus cardiac regulatory capacityGary G Berntson
Department of Psychology, The Ohio State University, 1835 Neil Avenue, Columbus, OH 43210, USA
Psychophysiology 45:643-52. 2008..Results reveal that CAR, but not CAB, was a significant predictor of the prior occurrence of a myocardial infarction, net of demographic and other variables, whereas CAB, but not CAR, was a significant predictor of concurrent diabetes... - May I have your attention, please: electrocortical responses to positive and negative stimuliN Kyle Smith
Department of Psychology, Ohio Wesleyan University, Phillips Hall, Delaware, OH 43015, USA
Neuropsychologia 41:171-83. 2003..This is (a) evidence for the extremely rapid (<120 ms) differentiation of positive and negative stimuli and (b) process-based evidence for a negativity bias in attention allocation... - Making sense by making sentient: effectance motivation increases anthropomorphismAdam Waytz
Department of Psychology, Harvard University, USA
J Pers Soc Psychol 99:410-35. 2010..Anthropomorphizing nonhuman agents seems to satisfy the basic motivation to make sense of an otherwise uncertain environment... - How can I connect with thee? Let me count the waysLouise C Hawkley
Institute for Mind and Biology, The University of Chicago, IL 60637, USA
Psychol Sci 16:798-804. 2005..Each facet was uniquely predicted by theoretically related social circumstances. These findings suggest how humans make meaning of their social relationships in their mental representations of loneliness and connectedness... - Perceived social isolation and cognitionJohn T Cacioppo
Center for Cognitive and Social Neuroscience, University of Chicago, 5848 S University Avenue, Chicago, IL 60637, USA
Trends Cogn Sci 13:447-54. 2009.... - Serum estrogen metabolites and systolic blood pressure among middle-aged and older women and menChristopher M Masi
Section of General Internal Medicine and the Department of Medicine, University of Chicago, IL, USA
Am J Hypertens 22:1148-53. 2009..We tested whether serum 17beta-estradiol (E(2)) or any of its metabolites were associated with SBP among middle-aged and older adults... - From social structural factors to perceptions of relationship quality and loneliness: the Chicago health, aging, and social relations studyLouise C Hawkley
Department of Psychology, University of Chicago, Biopsychological Sciences Building, 940 East 57th Street, Chicago, IL 60637, USA
J Gerontol B Psychol Sci Soc Sci 63:S375-84. 2008..The objective of this study was to test a conceptual model of loneliness in which social structural factors are posited to operate through proximal factors to influence perceptions of relationship quality and loneliness... - Estrogen metabolites and systolic blood pressure in a population-based sample of postmenopausal womenChristopher M Masi
Department of Medicine, University of Chicago, Chicago, Illinois 60637, USA
J Clin Endocrinol Metab 91:1015-20. 2006..Concentrations of 2-hydroxyestrone (2-OHE) and 16alpha-hydroxyestrone (16-OHE) in urine reflect the relative activity of the 2- and 16alpha-hydroxylation pathways of 17beta-estradiol... - Loneliness predicts reduced physical activity: cross-sectional & longitudinal analysesLouise C Hawkley
University of Chicago, Chicago, IL 60637, USA
Health Psychol 28:354-63. 2009..To determine cross-sectional and prospective associations between loneliness and physical activity, and to evaluate the roles of social control and emotion regulation as mediators of these associations... - Respiratory sinus arrhythmia and diseases of aging: obesity, diabetes mellitus, and hypertensionChristopher M Masi
Department of Medicine, University of Chicago, Chicago, IL 60637, USA
Biol Psychol 74:212-23. 2007..We conclude that the relationship between RSA and hypertension is somewhat independent of the age-related decline in parasympathetic activity... - Loneliness is a unique predictor of age-related differences in systolic blood pressureLouise C Hawkley
Chicago Center for Cognitive and Social Neuroscience, and Department of Psychology, University of Chicago, 5848 South University Avenue, Chicago, IL 60637, USA
Psychol Aging 21:152-64. 2006..Although the results are limited by the cross-sectional methods used, they are consistent with the hypothesis that cardiovascular disease contributes to increased morbidity and mortality among lonely individuals... - Loneliness matters: a theoretical and empirical review of consequences and mechanismsLouise C Hawkley
Center for Cognitive and Social Neuroscience, University of Chicago, Chicago, IL, USA
Ann Behav Med 40:218-27. 2010..Loneliness is not simply being alone. Interventions to reduce loneliness and its health consequences may need to take into account its attentional, confirmatory, and memorial biases as well as its social and behavioral effects... - Loneliness and pathways to diseaseLouise C Hawkley
Institute for Mind and Biology, The University of Chicago, 940 E 57th Street, IL 60637, USA
Brain Behav Immun 17:S98-105. 2003..For cancer patients, interventions should be aimed at providing instrumental support for the immediate demands of the disease... - Loneliness in everyday life: cardiovascular activity, psychosocial context, and health behaviorsLouise C Hawkley
Department of Psychology, University of Chicago, Illinois 60637, USA
J Pers Soc Psychol 85:105-20. 2003..Loneliness differences were not mediated by depressed affect or neuroticism. Social support mediated loneliness differences in stress and threat. Concomitants of loneliness were comparable for men and women... - Loneliness predicts increased blood pressure: 5-year cross-lagged analyses in middle-aged and older adultsLouise C Hawkley
Department of Psychology, University of Chicago, 940 East 57th Street, Chicago, IL 60637, USA
Psychol Aging 25:132-41. 2010..The effect of loneliness on SBP was independent of age, gender, race or ethnicity, cardiovascular risk factors, medications, health conditions, and the effects of depressive symptoms, social support, perceived stress, and hostility... - Stress and the aging immune systemLouise C Hawkley
Institute for Mind and Biology, The University of Chicago, 940 E 57th Street, Chicago, IL 60637, USA
Brain Behav Immun 18:114-9. 2004..Research on stress in older adults provides evidence that these processes contribute to effects that mimic, exacerbate, and possibly accelerate the effects of aging on immunity... - Loneliness impairs daytime functioning but not sleep durationLouise C Hawkley
Department of Psychology and Center for Cognitive and Social Neuroscience, University of Chicago, Chicago, IL 60637, USA
Health Psychol 29:124-9. 2010..To assess the prospective association between daily feelings of loneliness and subsequent feelings of daytime dysfunction indicative of poor sleep quality... - Job insecurity and change over time in health among older men and womenAriel Kalil
University of Chicago, IL 60637, USA
J Gerontol B Psychol Sci Soc Sci 65:81-90. 2010..We estimated associations between job insecurity and change over time in the physical and psychological health of older adult men and women... - Responses to ostracism across adulthoodLouise C Hawkley
Department of Psychology and Center for Cognitive and Social Neuroscience, University of Chicago, Chicago, IL 60637, USA
Soc Cogn Affect Neurosci 6:234-43. 2011.... - Gender and ethnic differences in urinary stress hormones: the population-based Chicago Health, Aging, and Social Relations StudyChristopher M Masi
Institute for Mind and Biology, University of Chicago, Chicago, Illinois 60637, USA
J Appl Physiol 97:941-7. 2004..The consistency of these results with previous studies of 24-h urine samples suggests muscle mass should be accounted for when comparing overnight urinary hormone values across gender and ethnicity... - Being bad isn't always good: affective context moderates the attention bias toward negative informationN Kyle Smith
Department of Psychology, Ohio Wesleyan University, Delaware, 43015, USA
J Pers Soc Psychol 90:210-20. 2006..The implications of this result for other biases to negative information and for the self-reinforcing nature of emotional disorders are discussed... - The interaction of social and emotional processes in the brainCatherine J Norris
Institute of Mind and Biology, University of Chicago, Chicago, IL 60637, USA
J Cogn Neurosci 16:1818-29. 2004..e., social, emotional, or both)... - Autonomic tone and C-reactive protein: a prospective population-based studyPuneet Singh
University of Chicago Pritzker School of Medicine, IL, USA
Clin Auton Res 19:367-74. 2009..To examine the cross-sectional and longitudinal relationships between cardiac autonomic tone and serum CRP and to investigate potential causal links between these measures... - Creating social connection through inferential reproduction: loneliness and perceived agency in gadgets, gods, and greyhoundsNicholas Epley
University of Chicago, Chicago, IL 60637, USA
Psychol Sci 19:114-20. 2008..These results have important implications not only for understanding when people are likely to treat nonhuman agents as humanlike (anthropomorphism), but also for understanding when people treat human agents as nonhuman (dehumanization)... - Differential mobilization of functionally distinct natural killer subsets during acute psychologic stressJos A Bosch
University of Illinois at Chicago, College of Dentistry, Chicago, IL 60611, USA
Psychosom Med 67:366-75. 2005..CONCLUSION: The marked specificity and robustness of these effects support the idea that NK cell mobilization is a functionally relevant response that is aimed at protecting the organism during acutely stressful situations... - Bridging psychology and biology. The analysis of individuals in groupsStephen M Kosslyn
Department of Psychology, Harvard University, 830 William James Hall, 33 Kirkland Street, Cambridge, MA 02138, USA
Am Psychol 57:341-51. 2002.... - Great expectations: what can fMRI research tell us about psychological phenomena?Tatjana Aue
Center for Cognitive and Social Neuroscience, University of Chicago, United States Swiss Center for Affective Sciences, University of Geneva, Switzerland
Int J Psychophysiol 73:10-6. 2009.... - Depressive symptoms predict mucosal wound healingJos A Bosch
University of Illinois at Chicago, College of Dentistry, Chicago, IL 60612, USA
Psychosom Med 69:597-605. 2007..Feelings of depression and social isolation are common among surgical patients, and the present study therefore investigated if these factors predict the rate of mucosal wound healing... - Neuroticism is associated with larger and more prolonged electrodermal responses to emotionally evocative picturesCatherine J Norris
Department of Psychology, University of Wisconsin Madison, Madison, Wisconsin 53705, USA
Psychophysiology 44:823-6. 2007..Implications for health are discussed... - Where to Q in PEPGary G Berntson
Department of Psychology, The Ohio State University, Columbus, Ohio 43210, USA
Psychophysiology 41:333-7. 2004..Conceptual, physiological, and empirical considerations addressing the reliability and validity of these alternative metrics support the application of the Q-wave peak/R-wave onset as the fiducial point for PEP measures... - Tracking the timecourse of social perception: the effects of racial cues on event-related brain potentialsTiffany A Ito
Department of Psychology, University of Colorado, 345 UCB, Boulder, CO 80309 0345, USA
Pers Soc Psychol Bull 30:1267-80. 2004..Together, the results demonstrate the promise of using neural processes to track the presence, timing, and degree of activation of components relevant to social perception, prejudice, and stereotyping... - Whither vagal toneGary G Berntson
The Ohio State University, Department of Psychology, Columbus, OH 43210, USA
Biol Psychol 74:295-300. 2007..We here consider the biological foundations for this view, discuss some methodological and interpretative caveats for RSA applications and offer suggestions for further development of the field... - Mucosal wound healing: the roles of age and sexChristopher G Engeland
Department of Periodontics, University of Illinois at Chicago, 801 S. Paulina Street, Chicago, IL 60612, USA
Arch Surg 141:1193-7; discussion 1198. 2006..These findings may help target patients with increased surgical risks and greater need for postsurgical care... - Autonomic and glucocorticoid associations with the steady-state expression of latent Epstein-Barr virusJohn T Cacioppo
University of Chicago, Illinois, USA
Horm Behav 42:32-41. 2002..Together, these studies raise the possibility that differences in the kinetics of glucocorticoid concentrations may contribute to differences in the reactivation of latent EBV... - Learning where to look for danger: integrating affective and spatial informationL Elizabeth Crawford
Department of Psychology, University of Richmond, VA 23173, USA
Psychol Sci 13:449-53. 2002..This asymmetry in representation may stem from underlying differences in the activation functions for positive and negative hedonic information processing... - Effects of positive and negative affect on electromyographic activity over zygomaticus major and corrugator superciliiJeff T Larsen
Department of Psychology, Texas Tech University, Lubbock, Texas 79409, USA
Psychophysiology 40:776-85. 2003..In addition, positive and negative affect ratings indicated that positive and negative affect have reciprocal effects on activity over corrugator supercilii, but not zygomaticus major... - The influence of facial feedback on race biasTiffany A Ito
Department of Psychology, 345 UCB, University of Colorado, Boulder, CO 80309 0345, USA
Psychol Sci 17:256-61. 2006.... - The agony of victory and thrill of defeat: Mixed emotional reactions to disappointing wins and relieving lossesJeff T Larsen
Department of Psychology, Texas Tech University, Lubbock 79409, USA
Psychol Sci 15:325-30. 2004..Results revealed that disappointing wins and relieving losses elicit positive and negative affect simultaneously, rather than in alternation... - Acute stress evokes selective mobilization of T cells that differ in chemokine receptor expression: a potential pathway linking immunologic reactivity to cardiovascular diseaseJos A Bosch
Periodontology Section, The Ohio State University, College of Dentistry, 305 West 12th Avenue, P.O. Box 182357, Columbus, OH 43218, USA
Brain Behav Immun 17:251-9. 2003..This mechanism may help explain the link between stress, reactivity, and cardiovascular disease... - Neuroendocrine and cardiovascular reactivity to stress in mid-aged and older women: long-term temporal consistency of individual differencesMary H Burleson
Department of Social and Behavioral Sciences, Arizona State University West, Phoenix, Arizona 85069, USA
Psychophysiology 40:358-69. 2003..65); consistency for other variables was moderate to low (rs approximately equal to .1-.4). Means of most variables changed from year to year. Results support the use of baseline, stressor, and posttask values in longitudinal studies... - Stress-related immune changes in middle-aged and older women: 1-year consistency of individual differencesMary H Burleson
Department of Social and Behavioral Sciences, Arizona State University West, Phoenix 85069 7100, USA
Health Psychol 21:321-31. 2002..Results support longitudinal study of psychosocial context effects on tonic immune function and posttask scores... - Spirituality and autonomic cardiac controlGary G Berntson
Ohio State University, 1835 Neil Avenue, Columbus, OH 43210, USA
Ann Behav Med 35:198-208. 2008..Spirituality has been suggested to be associated with positive health, but potential biological mediators have not been well characterized... - Compliance with ambulatory saliva sampling in the chicago health, aging, and social relations study and associations with social supportBrigitte M Kudielka
Graduate School of Psychobiology, University of Trier, Trier, Germany
Ann Behav Med 34:209-16. 2007..Noncompliance with instructed saliva sampling times in ambulatory settings can compromise resulting cortisol findings... - Longitudinal genetic analysis for loneliness in Dutch twinsDorret I Boomsma
Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands
Twin Res Hum Genet 10:267-73. 2007..Heritability for individual differences in the intercept was estimated at 77%. For the item 'Nobody loves me' no significant trend over age was seen; the heritability of the intercept was estimated at 70%... - Day-to-day dynamics of experience--cortisol associations in a population-based sample of older adultsEmma K Adam
School of Education and Social Policy and Cells to Society Center, Institute for Policy Research, Northwestern University, Evanston, IL 60208, USA
Proc Natl Acad Sci U S A 103:17058-63. 2006..Results are consistent with a dynamic and transactional function of cortisol as both a transducer of psychosocial and emotional experience into physiological activation and an influence on feelings of energy and physical well-being... - Objective and perceived neighborhood environment, individual SES and psychosocial factors, and self-rated health: an analysis of older adults in Cook County, IllinoisMing Wen
Department of Sociology, University of Utah, Salt Lake City, UT 84112 0250, USA
Soc Sci Med 63:2575-90. 2006..In sum, the research supports a model in which the effects of neighborhood SES on self-rated health act through sequential pathways of individual SES, perceptions of neighborhood quality, and psychosocial status... - Psychosocial and behavioral predictors of inflammation in middle-aged and older adults: the Chicago health, aging, and social relations studyThomas W McDade
Department of Anthropology, Northwestern University, 1810 Hinman Avenue, Evanston, Illinois 60208 1310, USA
Psychosom Med 68:376-81. 2006..We investigated the contribution of behavioral and psychosocial factors to variation in CRP concentrations in a population-based sample of middle-aged and older adults... - Ascending visceral regulation of cortical affective information processingGary G Berntson
Ohio State University, 1885 Neil Avenue, Columbus, OH 43210, USA
Eur J Neurosci 18:2103-9. 2003..The present paper highlights selected recent findings in this area, and outlines relevant structures and pathways involved in the ascending visceral influence on higher neurobehavioural processes... - Genetic linkage and association analysis for loneliness in Dutch twin and sibling pairs points to a region on chromosome 12q23-24Dorret I Boomsma
Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands
Behav Genet 36:137-46. 2006..043). We review evidence for linkage in this region for psychiatric disorders and discuss our findings within this context... - John T. Cacioppo. Award for Distinguished Scientific ContributionsJohn T Cacioppo
Am Psychol 57:817-9. 2002 - Genetic and environmental contributions to stability in loneliness throughout childhoodMeike Bartels
Department of Biological Psychology, VU University, Amsterdam, The Netherlands
Am J Med Genet B Neuropsychiatr Genet 147:385-91. 2008.... - Genetic and environmental contributions to loneliness in adults: the Netherlands twin register studyDorret I Boomsma
Vrije Universiteit, Van der Boechorststraat 1, 1081 Amsterdam, BT, The Netherlands
Behav Genet 35:745-52. 2005..All resemblance between twin relatives was explained by shared genes, without any suggestion of a contribution of shared environmental factors...
Research Grants
- Social Isolation, Loneliness, Health & the Aging ProcessJohn Cacioppo; Fiscal Year: 2005..There are also two cores that provide broad support to the projects: Core A the administrative Core, and Core B the data management and statistical management core. ..
- Social Isolation, Loneliness, Health & the Aging ProcessJohn Cacioppo; Fiscal Year: 2007..There are also two cores that provide broad support to the projects: Core A the administrative core, and Core B the data management and statistical management core. ..