Research Topics
| Daniel BuysseSummaryAffiliation: University of Pittsburgh Country: USA Publications
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Publications
Which symptoms predict recurrence of depression in women treated with maintenance interpersonal psychotherapy?Alexandre Y Dombrovski
Western Psychiatric Institute and Clinic, Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
Depress Anxiety 25:1060-6. 2008..We therefore examined the impact of persistent symptoms, including mood, insomnia, and anxiety symptoms, on time to recurrence in women receiving maintenance interpersonal psychotherapy (IPT-M) for recurrent depression...
InsomniaDaniel J Buysse
Neuroscience Clinical and Translational Research Center, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
JAMA 309:706-16. 2013..Clinicians may be reluctant to address insomnia because of its many potential causes, unfamiliarity with behavioral treatments, and concerns about pharmacologic treatments...
Regional brain glucose metabolism during morning and evening wakefulness in humans: preliminary findingsDaniel J Buysse
Department of Psychiatry, University of Pittsburgh School of Medicine, University of Pittsburgh Medical Center, Pennsylvania, USA
Sleep 27:1245-54. 2004..The goal of this pilot study was to examine regional relative brain glucose metabolism during morning and evening wakefulness in healthy humans...
Development and validation of patient-reported outcome measures for sleep disturbance and sleep-related impairmentsDaniel J Buysse
Department of Psychiatry, University of Pittsburgh School of Medicine, PA, USA
Sleep 33:781-92. 2010....
Recommendations for a standard research assessment of insomniaDaniel J Buysse
Department of Psychiatry, University of Pittsburgh School of Medicine, PA, USA
Sleep 29:1155-73. 2006..To present expert consensus recommendations for a standard set of research assessments in insomnia, reporting standards for these assessments, and recommendations for future research...
Chronic insomniaDaniel J Buysse
Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
Am J Psychiatry 165:678-86. 2008
Night-to-night sleep variability in older adults with and without chronic insomniaDaniel J Buysse
Sleep Medicine Institute and Neuroscience Clinical and Translational Research Center, Department of Psychiatry, School of Medicine, University of Pittsburgh, PA 15213, USA
Sleep Med 11:56-64. 2010....
EEG spectral analysis in primary insomnia: NREM period effects and sex differencesDaniel J Buysse
Neuroscience Clinical and Translational Research Center and Sleep Medicine Institute, University ofPittsburgh School ofMedicine, Pittsburgh, PA, USA
Sleep 31:1673-82. 2008..To compare NREM EEG power in primary insomnia (PI) and good sleeper controls (GSC), examining both sex and NREM period effects; to examine relationships between EEG power, clinical characteristics, and self-reports of sleep...
Daytime symptoms in primary insomnia: a prospective analysis using ecological momentary assessmentDaniel J Buysse
Neuroscience Clinical and Translational Research Center, Department of Psychiatry, University of Pittsburgh, School of Medicine, USA
Sleep Med 8:198-208. 2007....
Relationships between the Pittsburgh Sleep Quality Index (PSQI), Epworth Sleepiness Scale (ESS), and clinical/polysomnographic measures in a community sampleDaniel J Buysse
Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA
J Clin Sleep Med 4:563-71. 2008....
Fresh from the pipeline: RamelteonDaniel Buysse
University of Pittsburgh School of Medicine, Pennsylvania 15213, USA
Nat Rev Drug Discov 4:881-2. 2005
Can an improvement in sleep positively impact on health?Daniel J Buysse
University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
Sleep Med Rev 14:405-10. 2010..documents the debate session from the 6th International Sleep Disorders Forum -The Art of Good Sleep, held in Toronto, Canada in September 2008; the topic of which was "Does an improvement in sleep positively impact on health?"..
Prevalence, course, and comorbidity of insomnia and depression in young adultsDaniel J Buysse
Department ofPsychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
Sleep 31:473-80. 2008..1) To describe the prevalence and prospective course of insomnia in a representative young-adult sample and (2) to describe the cross-sectional and longitudinal associations between insomnia and depression...
Circadian patterns of sleep, sleepiness, and performance in older and younger adultsDaniel J Buysse
Sleep and Chronobiology Program, University of Pittsburgh, PA, USA
Sleep 28:1365-76. 2005..To compare circadian patterns of sleep, subjective sleepiness, and psychomotor performance in older and younger adults...
Efficacy of brief behavioral treatment for chronic insomnia in older adultsDaniel J Buysse
Sleep Medicine Institute, Department of Psychiatry, University of Pittsburgh School of Medicine, USA
Arch Intern Med 171:887-95. 2011..Cognitive behavioral treatments are efficacious but not widely available. The aim of this study was to test the efficacy of brief behavioral treatment for insomnia (BBTI) vs an information control (IC) condition...
Focusing on the experience of insomniaThomas J Carey
Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
Behav Sleep Med 3:73-86. 2005..Daytime problems are salient descriptors of the insomnia experience. Assessing the patient's daytime experiences is valued by patients with insomnia and may be used as a benchmark for treatment response...
Low life purpose and high hostility are related to an attenuated decline in nocturnal blood pressureElizabeth J Mezick
Department of Psychology, University of Pittsburgh, PA 15213, USA
Health Psychol 29:196-204. 2010..We investigated whether positive and negative psychological attributes were associated with sleep-wake BP ratios and examined sleep parameters as potential mediators of these relationships...
Influence of race and socioeconomic status on sleep: Pittsburgh SleepSCORE projectElizabeth J Mezick
Department of Psychology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Psychosom Med 70:410-6. 2008..To examine the independent and interactive effects of race and socioeconomic status (SES) on objective indices and self-reports of sleep...
Circadian and homeostatic modulation of sleep in older adults during a 90-minute day studyKeith A Niggemyer
Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh, Pennsylvania, USA
Sleep 27:1535-41. 2004..Age appears to affect circadian rhythmicity in higher EEG frequencies and homeostatic drive in lower EEG frequencies...
Comparison of sleep/wake behavior in CKD stages 4 to 5 and hemodialysis populations using wrist actigraphyBabak Barmar
Renal Electrolyte Division, University of Pittsburgh Medical Center, Pittsburgh, PA 15261, USA
Am J Kidney Dis 53:665-72. 2009..We assessed the influence of hemodialysis on sleep/wake behavior by using wrist actigraphy and self-reported sleep quality compared with patients with chronic kidney disease (CKD) stages 4 to 5...
Subjective and objective sleep quality in patients on conventional thrice-weekly hemodialysis: comparison with matched controls from the sleep heart health studyMark L Unruh
Renal Electrolyte Division, University of Pittsburgh Medical Center, Pittsburgh, PA 15261, USA
Am J Kidney Dis 52:305-13. 2008..It therefore is uncertain whether poor sleep quality in the HD population reflects age, chronic health conditions, or effects of conventional HD therapy...
Subjective and objective sleep quality and aging in the sleep heart health studyMark L Unruh
Renal Electrolyte Division, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15261, USA
J Am Geriatr Soc 56:1218-27. 2008..To examine the extent to which subjective and objective sleep quality are related to age independent of chronic health conditions...
Psychophysiological reactivity and coping styles influence the effects of acute stress exposure on rapid eye movement sleepAnne Germain
Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
Psychosom Med 65:857-64. 2003..Mediation and moderation models are more informative than traditional bivariate approaches to investigating the relation between stress exposure and sleep alterations...
Prevalence of obesity and weight change during treatment in patients with bipolar I disorderAndrea Fagiolini
Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, PA 15213, USA
J Clin Psychiatry 63:528-33. 2002....
Electroencephalographic sleep profiles in single-episode and recurrent unipolar forms of major depression: II. Comparison during remissionRipu D Jindal
Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania 15213, USA
Biol Psychiatry 51:230-6. 2002..Resolution of this issue requires longitudinal and family studies...
A pilot study of subjective daytime alertness and mood in primary insomnia participants using ecological momentary assessmentHelena Levitt
Department of Psychiatry, University of Pittsburgh School of Medicine, PA, USA
Behav Sleep Med 2:113-31. 2004..Coefficients of variation for DSD domains were greater in the insomnia group. Frequent measures of daytime symptoms may be useful outcomes in insomnia studies...
Effects of a brief behavioral treatment for late-life insomnia: preliminary findingsAnne Germain
Department Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
J Clin Sleep Med 2:403-6. 2006..CONCLUSION: BBTI was associated with significant improvements in sleep measures and in daytime symptoms of anxiety and depression. BBTI appears to be a promising intervention for older adults with insomnia...
Insomnia and hypersomnia associated with depressive phenomenology and comorbidity in childhood depressionXianchen Liu
Department of Psychiatry, University of Pittsburgh School of Medicine and WPIC, PA 15213, USA
Sleep 30:83-90. 2007....
Diagnosis and assessment of sleep and circadian rhythm disordersDaniel J Buysse
University of Pittsburgh School of Medicine, PA 15213, USA
J Psychiatr Pract 11:102-15. 2005..Methods of assessing sleep complaints are then described, including taking an accurate history from the patient and bed partner, use of sleep history questionnaires and sleep-wake diaries, use of actigraphy, and use of PSG...
Resistant hypertension and obstructive sleep apnea in the setting of kidney diseaseKhaled Abdel-Kader
Renal Electrolyte Division, University of Pittsburgh, Pittsburgh, PA 15261, USA
J Hypertens 30:960-6. 2012..To explore the relationship between obstructive sleep apnea (OSA) and resistant hypertension in chronic kidney disease (CKD) and end-stage renal disease (ESRD)...
Psychological stress is associated with heightened physiological arousal during NREM sleep in primary insomniaMartica Hall
Department of Psychiatry, University of Pittsburgh School of Medicine, 3811 O Hara Street, Pittsburgh, PA 15213, USA
Behav Sleep Med 5:178-93. 2007..Perceived stress and stress-related avoidance behaviors were associated with multiple indexes of physiological arousal during NREM sleep in patients with chronic, primary insomnia...
Blood pressure dipping and sleep disturbance in African-American and Caucasian men and womenKaren A Matthews
Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Am J Hypertens 21:826-31. 2008..Elevated night time/daytime blood pressure (BP) ratios are associated with cardiovascular morbidity and mortality. We evaluated the associations between sleep/awake BP ratios and sleep disturbances...
Marital quality and the marital bed: examining the covariation between relationship quality and sleepWendy M Troxel
Department of Psychiatry, University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA
Sleep Med Rev 11:389-404. 2007....
Sleep deprivation alters pupillary reactivity to emotional stimuli in healthy young adultsPeter L Franzen
Department of Psychiatry, University of Pittsburgh School of Medicine, 3811 O Hara St, Pittsburgh, PA 15213, USA
Biol Psychol 80:300-5. 2009..Such responses may have important implications for psychiatric disorders, which may be triggered or characterized by sleep disturbances...
Poor sleep quality predicts onset of either major depression or subsyndromal depression with irritability during interferon-alpha treatmentPeter L Franzen
Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
Psychiatry Res 177:240-5. 2010..These findings may have important implications for understanding, predicting, and possibly preventing depression, particularly in individuals treated with IFN-alpha...
Are inflammatory and coagulation biomarkers related to sleep characteristics in mid-life women?: Study of Women's Health across the Nation sleep studyKaren A Matthews
Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA
Sleep 33:1649-55. 2010....
Sleep symptoms predict the development of the metabolic syndromeWendy M Troxel
Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA
Sleep 33:1633-40. 2010..This is the first prospective study to report the association between commonly reported sleep symptoms and the development of the metabolic syndrome, a key CVD risk factor...
Sleep variability, health-related practices, and inflammatory markers in a community dwelling sample of older adultsMichele L Okun
Sleep Medicine Institute and Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
Psychosom Med 73:142-50. 2011..Health behaviors, including average aggregate measures of sleep, have been linked to increased inflammation in older adults. Variability in sleep timing may also be associated with increased inflammation...
Does social support differentially affect sleep in older adults with versus without insomnia?Wendy M Troxel
Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA
J Psychosom Res 69:459-66. 2010..We examined social support as a potential protective factor for sleep among older adults (60 years and older) with insomnia (n=79) and age- and sex-matched controls without insomnia (n=40)...
Napping, nighttime sleep, and cardiovascular risk factors in mid-life adultsJane F Owens
Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA
J Clin Sleep Med 6:330-5. 2010..To evaluate the relations between sleep characteristics and cardiovascular risk factors and napping behavior, and to assess whether daytime napping leads to subsequent better or worse sleep...
Marital/cohabitation status and history in relation to sleep in midlife womenWendy M Troxel
Department of Psychiatry, University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA
Sleep 33:973-81. 2010..To examine whether current and/or history of marital/cohabitation status are associated with sleep, independent of demographic and general health risk factors...
Maintenance treatment of insomnia: what can we learn from the depression literature?Ripu D Jindal
Mental Health Intervention Research Center, University of Pittsburgh School of Medicine, PA 15213, USA
Am J Psychiatry 161:19-24. 2004..This article compares and contrasts the current state of research in the maintenance therapy of depression and insomnia and highlights gaps in the insomnia literature...
Comorbid insomnia and obstructive sleep apnea: challenges for clinical practice and researchFaith S Luyster
Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15261, USA
J Clin Sleep Med 6:196-204. 2010....
Sleep quality, mood, alertness and their variability in CKD and ESRDMaria Eleni Roumelioti
Renal Electrolyte Division, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
Nephron Clin Pract 114:c277-87. 2010..In this report, we assessed these symptoms among patients with advanced CKD (stages 4-5) and those with end-stage renal disease (ESRD) and compared them to healthy controls without known kidney disease...
What constitutes too long of a delay? Determining the cortisol awakening response (CAR) using self-report and PSG-assessed wake timeMichele L Okun
University of Pittsburgh School of Medicine, Department of Psychiatry, United States
Psychoneuroendocrinology 35:460-8. 2010..Later collection times and reduced CAR values may affect the interpretation of clinical associations. Our data also show that S-R assessments of wake time perform equally well to PSG for evaluating adherence with CAR sampling procedures...
Effects of a two-hour change in bedtime on the sleep of healthy seniorsTimothy H Monk
Neuroscience Clinical and Translational Research Center, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
Chronobiol Int 26:526-43. 2009..There were no effects related to the phase angle between Tmin and rise-time. The relative benefits of longer vs. more efficient sleep in the elderly require further investigation...
Psychometric evaluation of the Insomnia Symptom Questionnaire: a self-report measure to identify chronic insomniaMichele L Okun
University of Pittsburgh, Department of Psychiatry, Pittsburgh, PA 15213, USA
J Clin Sleep Med 5:41-51. 2009....
Race and financial strain are independent correlates of sleep in midlife women: the SWAN sleep studyMartica H Hall
Department of Psychiatry University of Pittsburgh, Pittsburgh, PA 15213, USA
Sleep 32:73-82. 2009..To examine racial differences in sleep in a large cohort of midlife women and to evaluate whether indices of socioeconomic status (SES) are associated with racial differences in sleep...
Circadian type and bed-timing regularity in 654 retired seniors: correlations with subjective sleep measuresTimothy H Monk
Neuroscience Clinical and Translational Research Center, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, 3811 O Hara Street, Pittsburgh, PA 15213, USA
Sleep 34:235-9. 2011..Using telephone interview data from retired seniors to explore how inter-individual differences in circadian type (morningness) and bed-timing regularity might be related to subjective sleep quality and quantity...
Relationship of variability in residual symptoms with recurrence of major depressive disorder during maintenance treatmentJordan F Karp
Western Psychiatric Institute and Clinic, 3811 O Hara St, Pittsburgh, PA 15213, USA
Am J Psychiatry 161:1877-84. 2004....
Paroxetine treatment of primary insomnia in older adultsCharles F Reynolds
Advanced Center for Interventions and Services Research for Late Life Mood Disorders ACISR LLMD and the John A Hartford Center of Excellence in Geriatric Psychiatry, Western Psychiatric Institute and Clinic, Pittsburgh, PA, USA
Am J Geriatr Psychiatry 14:803-7. 2006..The goal of this study was to test the efficacy of paroxetine for primary insomnia in older adults...
Sleep in healthy seniors: a diary study of the relation between bedtime and the amount of sleep obtainedTimothy H Monk
Clinical Neuroscience Research Center, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, PA 15213, USA
J Sleep Res 15:256-60. 2006..g. age-dependent alterations in phase angle and homeostatic sleep need)...
Age-related differences in the lifestyle regularity of seniors experiencing bereavement, care-giving, insomnia, and advancement into old-old ageTimothy H Monk
Clinical Neuroscience Research Center, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
Chronobiol Int 23:831-41. 2006..This may represent an adaptive behavioral response that might be used in future therapeutic approaches...
Treating complicated grief: effects on sleep qualityAnne Germain
Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
Behav Sleep Med 4:152-63. 2006..Given that sleep disturbance is a risk factor for poor health outcomes, adjunctive sleep interventions may be necessary to enhance CGT outcomes...
Human regional cerebral glucose metabolism during non-rapid eye movement sleep in relation to wakingEric A Nofzinger
Department of Psychiatry, University of Pittsburgh School of Medicine, PA 15213 2593, USA
Brain 125:1105-15. 2002....
Sleep quality in complicated griefAnne Germain
Department of Psychiatry, University of Pittsburgh School of Medicine, Pennsylvania 15213, USA
J Trauma Stress 18:343-6. 2005..Comorbid depression, but not PTSD, further worsened sleep quality. Further studies are required to investigate the potential role of poor sleep quality as a modifiable risk factor of complicated grief response...
Alterations in regional cerebral glucose metabolism across waking and non-rapid eye movement sleep in depressionEric A Nofzinger
Department of Psychiatry, Western Psychiatric Institute and Clinic, 3811 O Hara Street, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
Arch Gen Psychiatry 62:387-96. 2005..Non-rapid eye movement sleep is associated with decreases in frontal, parietal, and temporal cortex metabolic activity compared with wakefulness...
Clinical correlates of poor sleep quality in posttraumatic stress disorderAnne Germain
Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
J Trauma Stress 17:477-84. 2004..Results suggest that age, gender, and psychiatric comorbidity have minimal impact on sleep quality in this PTSD sample. The inclusion of PTSD patients who were not specifically seeking treatment for SD reinforces the study findings...
Using nine 2-h delays to achieve a 6-h advance disrupts sleep, alertness, and circadian rhythmTimothy H Monk
Clinical Neuroscience Research Center, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
Aviat Space Environ Med 75:1049-57. 2004....
Can sleep be bad for you? Can insomnia be good?Daniel J Buysse
E 1127 TDH, Western Psychiatric Institute and Clinic, 3811 O Hara St, Pittsburgh, PA 15213, USA
Arch Gen Psychiatry 59:137-8. 2002
Self-report measures of insomnia in adults: rationales, choices, and needsDouglas E Moul
Department of Psychiatry, Western Psychiatric Institute and Clinic, Sleep and Chronobiology Center, University of Pittsburgh, Room E 1119, 3811 O Hara Street, Pittsburgh, PA 15213, USA
Sleep Med Rev 8:177-98. 2004..An extensive table of currently available questionnaires is provided, and some needs for future questionnaire development are also identified...
Randomized trial of weekly, twice-monthly, and monthly interpersonal psychotherapy as maintenance treatment for women with recurrent depressionEllen Frank
Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, 3811 O Hara St, Pittsburgh, PA 15213, USA
Am J Psychiatry 164:761-7. 2007..The authors sought to determine whether a greater frequency of interpersonal psychotherapy (IPT) sessions during maintenance treatment has a greater prophylactic effect than a previously validated once-a-month treatment...
Masking effects of posture and sleep onset on core body temperature have distinct circadian rhythms: results from a 90-min/day protocolDouglas E Moul
Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, PA 15213, USA
J Biol Rhythms 17:447-62. 2002..These findings confirm the need for nonlinear models of temperature responses to postural changes and sleep that incorporate circadian variability in these masking effects...
Symptom reports in severe chronic insomniaDouglas E Moul
Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, PA 15213, USA
Sleep 25:553-63. 2002..To describe patterns and severities of the daytime and nighttime symptoms of chronic insomnia patients...
Functional neuroimaging evidence for hyperarousal in insomniaEric A Nofzinger
Western Psychiatric Institute and Clinic, Sleep Neuroimaging Research Program, Department of Psychiatry, University of Pittsburgh School of Medicine, 3811 O Hara St, Pittsburgh, PA 15213 2593, USA
Am J Psychiatry 161:2126-8. 2004..The authors investigated the neurobiological basis of poor sleep and daytime fatigue in insomnia...
The relationship between lifestyle regularity and subjective sleep qualityTimothy H Monk
Clinical Neuroscience Research Center, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
Chronobiol Int 20:97-107. 2003..Thus, there appears to be an association between lifestyle regularity and good sleep, though the direction of causality remains to be tested...
Effects of a brief behavioral treatment for PTSD-related sleep disturbances: a pilot studyAnne Germain
Department of Psychiatry, University of Pittsburgh School of Medicine, PA, USA
Behav Res Ther 45:627-32. 2007..The goal of this pilot study was to explore the effects of a very brief intervention for PTSD-related nightmares and insomnia in victims of violent crimes with PTSD...
Clinicians' use of the International Classification of Sleep Disorders: results of a national surveyDaniel J Buysse
University of Pittsburgh, Pittsburgh, PA, USA
Sleep 26:48-51. 2003..To determine clinicians' patterns of use of the International Classification of Sleep Disorders (ICSD) and their ratings of its utility and organization...
Self-reported sleep quality predicts poor cognitive performance in healthy older adultsRobert D Nebes
Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, PA 15213, USA
J Gerontol B Psychol Sci Soc Sci 64:180-7. 2009..Sleep problems may contribute to performance variability between elderly individuals but only in certain cognitive domains...
Morningness-eveningness and lifestyle regularityTimothy H Monk
Clinical Neuroscience Research Center, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
Chronobiol Int 21:435-43. 2004..Thus it appears that morning types appear to be more regular in their daily lifestyle than are evening types, suggesting a relationship between these two aspects of human circadian behavior...
Acute stress affects heart rate variability during sleepMartica Hall
University of Pittsburgh Department of Psychiatry, Pittsburgh, PA, USA
Psychosom Med 66:56-62. 2004..In this study, we used autoregressive spectral analysis of the electrocardiogram (EKG) interbeat interval sequence to characterize stress-related changes in heart rate variability during sleep in 59 healthy men and women...
Neurobiology of non-REM sleep in depression: further evidence for hypofrontality and thalamic dysregulationAnne Germain
University of Pittsburgh School of Medicine, Department of Psychiatry, 3811 O Hara St, E 1116, Pittsburgh, PA 15213, USA
Am J Psychiatry 161:1856-63. 2004..The goal of this study was to investigate the functional neuroanatomical correlates of non-REM sleep relative to presleep wakefulness in depressed patients and healthy subjects...
Functional neuroanatomical correlates of eye movements during rapid eye movement sleep in depressed patientsAnne Germain
Department of Psychiatry, University of Pittsburgh School of Medicine, 3811 O Hara Street, E 1116, Pittsburgh, PA 15213, USA
Psychiatry Res 130:259-68. 2004..The observed pattern of correlations suggests that average RC may be a marker of hypofrontality during REM sleep in depressed patients...
The association between short sleep duration and obesity in young adults: a 13-year prospective studyGregor Hasler
Mood and Anxiety Disorders Program, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA
Sleep 27:661-6. 2004..The objective of this study was to test the hypothesis that short sleep duration is associated with obesity and weight gain during young adulthood...
Measuring sleep habits without using a diary: the sleep timing questionnaireTimothy H Monk
Clinical Neuroscience Research Center, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, PA 15213, USA
Sleep 26:208-12. 2003..To develop a single-administration instrument yielding equivalent measures of sleep to those obtained from a formal (2-week) sleep diary...
Microstructure of sleep in depressed patients according to the cyclic alternating patternBenedetto Farina
Institute of Psychiatry, Catholic University of Sacred Heart, via Alexander Fleming 110, 00191, Rome, Italy
J Affect Disord 77:227-35. 2003..The aim of this study was to evaluate the microstructure of the EEG sleep of depressed subjects by cyclic alternating pattern (CAP) analysis...
Increased activation of anterior paralimbic and executive cortex from waking to rapid eye movement sleep in depressionEric A Nofzinger
Department of Psychiatry, University of Pittsburgh School of Medicine, PA 15213 2593, USA
Arch Gen Psychiatry 61:695-702. 2004....
A brief sleep scale for Posttraumatic Stress Disorder: Pittsburgh Sleep Quality Index Addendum for PTSDAnne Germain
Department of Psychiatry, University of Pittsburgh School of Medicine, PA 15213, USA
J Anxiety Disord 19:233-44. 2005..The PSQI-A is a valid instrument for PTSD applicable to both clinical and research settings...
Chronic insomnia and MRI-measured hippocampal volumes: a pilot studyDieter Riemann
Department of Psychiatry and Psychotherapy, Freiburg University Medical Center, Hauptstr 5, D 79104 Germany
Sleep 30:955-8. 2007..Morphometric analysis of magnetic resonance imaging brain scans was used to investigate possible neuroanatomic differences between patients with primary insomnia compared to good sleepers...
Attachment anxiety, relationship context, and sleep in women with recurrent major depressionWendy M Troxel
Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA
Psychosom Med 69:692-9. 2007..To examine the relationship between attachment anxiety, marital status, bed-partner status, and sleep in recurrently depressed women...
Examining initial sleep onset in primary insomnia: a case-control study using 4-second epochsDouglas E Moul
University of Pittsburgh, Department of Psychiatry, Pittsburgh, PA, USA
J Clin Sleep Med 3:479-88. 2007..Conventional scorings in 20-second and 60-second epochs were also obtained...
Financial strain is a significant correlate of sleep continuity disturbances in late-lifeMartica Hall
Department of Psychiatry, University of Pittsburgh School of Medicine, 3811 O Hara Street, Pittsburgh, PA 15213, United States
Biol Psychol 77:217-22. 2008..01). Our results show that chronic stress, as measured by ongoing financial strain, is a significant correlate of sleep disturbances in the elderly, even after adjusting for factors known to impact sleep in late-life...
Relationships between affect, vigilance, and sleepiness following sleep deprivationPeter L Franzen
Department of Psychiatry, University of Pittsburgh School of Medicine, PA, USA
J Sleep Res 17:34-41. 2008..By including affective outcomes in experimental sleep deprivation research, the impact of sleep loss on affective function and their relationship to other neurobehavioral domains can be assessed...
Self-reported sleep quality is associated with the metabolic syndromeJ Richard Jennings
Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA
Sleep 30:219-23. 2007..To determine whether a simple, structured self-report of overall sleep quality is associated with the presence of the metabolic syndrome and its component risk factors...
Diurnal variation in regional brain glucose metabolism in depressionAnne Germain
Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
Biol Psychiatry 62:438-45. 2007..This study compared diurnal variation in mood and regional cerebral metabolic rate of glucose (rCMRglc) in depressed and healthy subjects...
Psychological and behavioral treatment of insomnia:update of the recent evidence (1998-2004)Charles M Morin
Universite Laval, Quebec, Canada
Sleep 29:1398-414. 2006..As with the original paper, this review was conducted by a task force commissioned by the American Academy of Sleep Medicine in order to update its practice parameters on psychological and behavioral therapies for insomnia...
Self-reported sleep duration is associated with the metabolic syndrome in midlife adultsMartica H Hall
Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
Sleep 31:635-43. 2008..In the present study, we evaluated the relationship between sleep duration and presence of the metabolic syndrome, which is a cluster of physiologically interrelated risk factors for cardiometabolic disease...
Using daily 30-min phase advances to achieve a 6-hour advance: circadian rhythm, sleep, and alertnessTimothy H Monk
Clinical Neuroscience Research Center, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
Aviat Space Environ Med 77:677-86. 2006....
Excessive daytime sleepiness in young adults: a 20-year prospective community studyGregor Hasler
Mood and Anxiety Disorders Program, Intramural Research Program, National Institutes of Health, National Institute of Mental Health, Bethesda, MD 20892, USA
J Clin Psychiatry 66:521-9. 2005..The aim of this study was to explore associations between self-reported EDS, sleep disorder symptoms, major depression, and anxiety in a longitudinal community study of young adults...
Sleep-specific mechanisms underlying posttraumatic stress disorder: integrative review and neurobiological hypothesesAnne Germain
Department of Psychiatry, University of Pittsburgh School of Medicine, 3811 O Hara Street, Room E 1124, Pittsburgh, PA 15213, USA
Sleep Med Rev 12:185-95. 2008..Testable hypotheses regarding the neurobiological underpinnings of PTSD across the sleep-wake cycle are offered...
Regional cerebral metabolic correlates of WASO during NREM sleep in insomniaEric A Nofzinger
Western Psychiatric Institute and Clinic, Sleep Neuroimaging Research Program, Department of Psychiatry, University of Pittsburgh School of Medicine, 3811 O Hara Street, Pittsburgh, PA 15213 2593, USA
J Clin Sleep Med 2:316-22. 2006..To investigate the non-rapid eye movement (NREM) sleep-related regional cerebral metabolic correlates of wakefulness after sleep onset (WASO) in patients with primary insomnia...
Research Grants
- 2/3-Improving Depression Outcome by Adding CBT for Insomnia to AntidepressantsDaniel J Buysse; Fiscal Year: 2010..The results of this study may offer a method for improving the treatment of major depression without the use of additional medication. ..
- Testing a Neurobiological Model of Primary InsomniaDaniel Buysse; Fiscal Year: 2009..Results of this study could help us to better understand how the brain functions during sleep and wakefulness in people with insomnia, and how behavioral treatments (such as sleep restriction) might work. ..
- Testing a Neurobiological Model of Primary InsomniaDaniel Buysse; Fiscal Year: 2007..Results of this study could help us to better understand how the brain functions during sleep and wakefulness in people with insomnia, and how behavioral treatments (such as sleep restriction) might work. ..
- Translational Research Training in Sleep MedicineDaniel Buysse; Fiscal Year: 2007..The medical student research experiences are designed to stimulate interest in Sleep Medicine specifically, and to address the critical "pipeline" issue facing translational research in a more general sense. ..
- Psychobiology and Treatment Response in Primary InsomniaDaniel Buysse; Fiscal Year: 2006..abstract_text> ..
- RATIONAL PHARMACOTHERAPY OF PRIMARY INSOMNIADaniel Buysse; Fiscal Year: 2004..The Principal Investigator will mentor trainees in analyses of existing data, design and implementation of the clinical trial, described above, and new studies designed by the trainees themselves. ..
- Testing a Neurobiological Model of Primary InsomniaDaniel J Buysse; Fiscal Year: 2010..Results of this study could help us to better understand how the brain functions during sleep and wakefulness in people with insomnia, and how behavioral treatments (such as sleep restriction) might work. ..
