Kelly J Butnor

Summary

Affiliation: University of Vermont
Country: USA

Publications

  1. doi request reprint p40 (ΔNp63) and keratin 34βE12 provide greater diagnostic accuracy than p63 in the evaluation of small cell lung carcinoma in small biopsy samples
    Kelly J Butnor
    The University of Vermont Fletcher Allen Health Care, Burlington, VT 05401, USA
    Hum Pathol 44:1479-86. 2013
  2. doi request reprint Avoiding underdiagnosis, overdiagnosis, and misdiagnosis of lung carcinoma
    Kelly J Butnor
    Department of Pathology, University of Vermont Fletcher Allen Health Care, Burlington, VT 05401, USA
    Arch Pathol Lab Med 132:1118-32. 2008
  3. doi request reprint Uroplakin is not a reliable immunohistochemical marker for malignant mesothelioma of the pleura
    Kelly J Butnor
    The University of Vermont, Burlington, VT, USA
    Appl Immunohistochem Mol Morphol 16:326-8. 2008
  4. ncbi request reprint Resolving dilemmas in lung cancer staging and histologic typing
    Kelly J Butnor
    Department of Pathology, Fletcher Allen Health Care University of Vermont, Burlington 05401, USA
    Arch Pathol Lab Med 131:1014-5. 2007
  5. ncbi request reprint Recommendations for the reporting of pleural mesothelioma
    Kelly J Butnor
    Department of Pathology, University of Vermont, Burlington, VT, USA
    Virchows Arch 450:15-23. 2007
  6. ncbi request reprint Recommendations for the reporting of pleural mesothelioma
    Kelly J Butnor
    Department of Pathology, University of Vermont, 111 Colchester Avenue, Burlington, VT 05401, USA
    Hum Pathol 38:1587-9. 2007
  7. ncbi request reprint Expression of renal cell carcinoma-associated markers erythropoietin, CD10, and renal cell carcinoma marker in diffuse malignant mesothelioma and metastatic renal cell carcinoma
    Kelly J Butnor
    Department of Pathology, University of Vermont Fletcher Allen Health Care, Burlington, VT 05401, USA
    Arch Pathol Lab Med 130:823-7. 2006
  8. ncbi request reprint Pleuropulmonary pathology of Birt-Hogg-Dubé syndrome
    Kelly J Butnor
    Department of Pathology, University of Vermont, Burlington 05401, USA
    Am J Surg Pathol 30:395-9. 2006
  9. ncbi request reprint Pulmonary sarcoidosis induced by interferon-alpha therapy
    Kelly J Butnor
    Department of Pathology, University of Vermont, Burlington, VT, USA
    Am J Surg Pathol 29:976-9. 2005
  10. ncbi request reprint Human parainfluenza virus giant cell pneumonia following cord blood transplant associated with pulmonary alveolar proteinosis
    Kelly J Butnor
    Department of Pathology, Duke University Medical Center, Durham, NC, USA
    Arch Pathol Lab Med 127:235-8. 2003

Collaborators

Detail Information

Publications35

  1. doi request reprint p40 (ΔNp63) and keratin 34βE12 provide greater diagnostic accuracy than p63 in the evaluation of small cell lung carcinoma in small biopsy samples
    Kelly J Butnor
    The University of Vermont Fletcher Allen Health Care, Burlington, VT 05401, USA
    Hum Pathol 44:1479-86. 2013
    ..To provide greater diagnostic accuracy, p40 (ΔNp63) or keratin 34βE12 should be used instead of p63 in the distinction of small cell lung carcinoma from non-small cell lung carcinoma in biopsy samples. ..
  2. doi request reprint Avoiding underdiagnosis, overdiagnosis, and misdiagnosis of lung carcinoma
    Kelly J Butnor
    Department of Pathology, University of Vermont Fletcher Allen Health Care, Burlington, VT 05401, USA
    Arch Pathol Lab Med 132:1118-32. 2008
    ..This can sometimes be a formidable challenge, as a number of benign entities mimic lung carcinoma and vice versa...
  3. doi request reprint Uroplakin is not a reliable immunohistochemical marker for malignant mesothelioma of the pleura
    Kelly J Butnor
    The University of Vermont, Burlington, VT, USA
    Appl Immunohistochem Mol Morphol 16:326-8. 2008
    ..To analyze the immunohistochemical expression of uroplakin (URO) in pleural malignant mesothelioma (PMM)...
  4. ncbi request reprint Resolving dilemmas in lung cancer staging and histologic typing
    Kelly J Butnor
    Department of Pathology, Fletcher Allen Health Care University of Vermont, Burlington 05401, USA
    Arch Pathol Lab Med 131:1014-5. 2007
  5. ncbi request reprint Recommendations for the reporting of pleural mesothelioma
    Kelly J Butnor
    Department of Pathology, University of Vermont, Burlington, VT, USA
    Virchows Arch 450:15-23. 2007
  6. ncbi request reprint Recommendations for the reporting of pleural mesothelioma
    Kelly J Butnor
    Department of Pathology, University of Vermont, 111 Colchester Avenue, Burlington, VT 05401, USA
    Hum Pathol 38:1587-9. 2007
    ..However, the ADASP hopes that pathologists will find these checklists to be useful in daily clinical practice, while facilitating compliance with the new COC requirements...
  7. ncbi request reprint Expression of renal cell carcinoma-associated markers erythropoietin, CD10, and renal cell carcinoma marker in diffuse malignant mesothelioma and metastatic renal cell carcinoma
    Kelly J Butnor
    Department of Pathology, University of Vermont Fletcher Allen Health Care, Burlington, VT 05401, USA
    Arch Pathol Lab Med 130:823-7. 2006
    ..Standard panels of immunohistochemical markers are of limited benefit...
  8. ncbi request reprint Pleuropulmonary pathology of Birt-Hogg-Dubé syndrome
    Kelly J Butnor
    Department of Pathology, University of Vermont, Burlington 05401, USA
    Am J Surg Pathol 30:395-9. 2006
    ..Pathologists should raise the possibility of BHD in nonapical lung biopsies from young or middle-aged patients that show blebs or cysts...
  9. ncbi request reprint Pulmonary sarcoidosis induced by interferon-alpha therapy
    Kelly J Butnor
    Department of Pathology, University of Vermont, Burlington, VT, USA
    Am J Surg Pathol 29:976-9. 2005
    ....
  10. ncbi request reprint Human parainfluenza virus giant cell pneumonia following cord blood transplant associated with pulmonary alveolar proteinosis
    Kelly J Butnor
    Department of Pathology, Duke University Medical Center, Durham, NC, USA
    Arch Pathol Lab Med 127:235-8. 2003
    ..To our knowledge, a unique associated feature of this case, a pulmonary alveolar proteinosis-like reaction, has not been reported previously in association with human parainfluenza virus pneumonia...
  11. ncbi request reprint Beryllium detection in human lung tissue using electron probe X-ray microanalysis
    Kelly J Butnor
    Department of Pathology, University of Vermont, Burlington, Vermont, USA
    Mod Pathol 16:1171-7. 2003
    ..This application of EDXA offers significant advantages over existing methods of beryllium detection in that it is nondestructive, more widely available, and can be performed using routine paraffin sections...
  12. ncbi request reprint The spectrum of Kit (CD117) immunoreactivity in lung and pleural tumors: a study of 96 cases using a single-source antibody with a review of the literature
    Kelly J Butnor
    Department of Pathology, University of Vermont, Burlington, VT, USA
    Arch Pathol Lab Med 128:538-43. 2004
    ..Likewise, while solitary fibrous tumors of the gastrointestinal tract have been examined for Kit expression, the Kit staining characteristics of their counterpart in the pleura, namely, localized fibrous tumor, are not well known...
  13. ncbi request reprint Visceral pleural invasion in lung cancer: recognizing histologic parameters that impact staging and prognosis
    Kelly J Butnor
    Department of Pathology, University of Vermont, Fletcher Allen Health Care, 111 Colchester Ave, MCHV Campus, Smith 246B, Burlington, VT 05401, USA
    Adv Anat Pathol 12:1-6. 2005
    ..Elastic stains can be instrumental in detecting disruptions of the visceral pleural elastic layer by tumor, a finding that has prognostic and staging implications similar to tumor that is present on the visceral pleural surface...
  14. ncbi request reprint Airway epithelial NF-kappaB activation modulates asbestos-induced inflammation and mucin production in vivo
    Astrid Haegens
    Department of Pathology, University of Vermont College of Medicine, 89 Beaumont Avenue, Burlington, VT 05405, USA
    J Immunol 178:1800-8. 2007
    ..05) in Tg(+) vs Tg(-) mice. Our findings demonstrate that airway epithelial NF-kappaB activity plays a role in orchestrating the inflammatory response as well as cell proliferation in response to asbestos...
  15. pmc ERK2 is essential for the growth of human epithelioid malignant mesotheliomas
    Arti Shukla
    Department of Pathology, University of Vermont College of Medicine, Burlington, VT 05405 0068, USA
    Int J Cancer 129:1075-86. 2011
    ..After injection of sarcomatoid human MM (PPMMill) cells into SCID mice, both shERK1 and shERK2 lines showed significant decreased tumor growth, suggesting heterogeneous effects of ERKs in individual MMs...
  16. pmc Decreased asbestos-induced lung inflammation and fibrosis after radiation and bone marrow transplant
    Jamie Levis
    Pulmonary and Critical Care, University of Vermont College of Medicine, Burlington, VT 05405, USA
    Am J Respir Cell Mol Biol 38:16-25. 2008
    ..Irradiation and bone marrow transplantation alters inflammatory and fibrotic responses to asbestos, likely through modulation of soluble inflammatory mediators...
  17. pmc Inflammation precedes the development of human malignant mesotheliomas in a SCID mouse xenograft model
    Jedd M Hillegass
    Department of Pathology, University of Vermont College of Medicine, Burlington, Vermont, USA
    Ann N Y Acad Sci 1203:7-14. 2010
    ..Results suggest that inflammation and cytokine production precede and may be critical to the development of MMs...
  18. pmc A multifunctional mesothelin antibody-tagged microparticle targets human mesotheliomas
    Sherrill L Macura
    Department of Pathology, University of Vermont College of Medicine, Burlington, VT 05405, USA
    J Histochem Cytochem 60:658-74. 2012
    ....
  19. ncbi request reprint Exposure to brake dust and malignant mesothelioma: a study of 10 cases with mineral fiber analyses
    Kelly J Butnor
    University of Vermont Medical Center, Department of Pathology, Burlington, VT 05405, USA
    Ann Occup Hyg 47:325-30. 2003
    ..We present our experience of MM in individuals whose only known asbestos exposure was to brake dust and correlate these findings with lung asbestos fiber burdens...
  20. ncbi request reprint Asbestos-induced lung inflammation and epithelial cell proliferation are altered in myeloperoxidase-null mice
    Astrid Haegens
    Department of Pathology, College of Medicine, University of Vermont, Burlington, Vermont 05404, USA
    Cancer Res 65:9670-7. 2005
    ..These results support the hypothesis that myeloperoxidase status modulates early asbestos-induced oxidative stress, epithelial cell proliferation, and inflammation...
  21. pmc Inhaled asbestos exacerbates atherosclerosis in apolipoprotein E-deficient mice via CD4+ T cells
    Naomi K Fukagawa
    Department of Medicine, University of Vermont College of Medicine, Burlington, Vermont 05405, USA
    Environ Health Perspect 116:1218-25. 2008
    ....
  22. pmc Gene expression profiles reveal increased mClca3 (Gob5) expression and mucin production in a murine model of asbestos-induced fibrogenesis
    Tara Sabo-Attwood
    Department of Pathology, University of Vermont, 89 Beaumont Ave, HSRF 218, Burlington, VT 05405, and the Pediatric Pulmonary Division, Children s Hospital of Pittsburgh, PA, USA
    Am J Pathol 167:1243-56. 2005
    ..Identification of genes involved in lung injury and remodeling after asbestos exposure could aid in defining mechanisms of airborne particulate-induced disease and in developing therapeutic strategies...
  23. pmc Asbestos-induced peribronchiolar cell proliferation and cytokine production are attenuated in lungs of protein kinase C-delta knockout mice
    Arti Shukla
    Department of Pathology, University of Vermont, 89 Beaumont Ave, Burlington, VT 05405, USA
    Am J Pathol 170:140-51. 2007
    ..These results also implicate targeted interruption of PKC-delta as a potential therapeutic option in asbestos-induced lung diseases...
  24. pmc Activated cAMP response element binding protein is overexpressed in human mesotheliomas and inhibits apoptosis
    Arti Shukla
    Department of Pathology, University of Vermont College of Medicine, Burlington, VT 05405 0068, USA
    Am J Pathol 175:2197-206. 2009
    ..Since activated CREB1 also is increased endogenously in human MM and modifies migration and resistance to Dox-induced apoptosis, inhibition of CREB1 may be a new strategy for MM therapy...
  25. pmc Increased efficacy of doxorubicin delivered in multifunctional microparticles for mesothelioma therapy
    Jedd M Hillegass
    Department of Pathology, University of Vermont College of Medicine, Burlington, VT 05405 0068, USA
    Int J Cancer 129:233-44. 2011
    ..These results suggest APMS are efficacious for the localized delivery of lower effective DOX concentrations in MM and represent a novel means of treating intracavitary tumors...
  26. ncbi request reprint Tremolite and mesothelioma
    Victor L Roggli
    Department of Pathology, Duke University and Durham VA Medical Centers, NC 27710, USA
    Ann Occup Hyg 46:447-53. 2002
    ..Tremolite also contaminates talc, the most common non-asbestos mineral fiber in our control cases...
  27. ncbi request reprint Interobserver agreement on what constitutes visceral pleural invasion by non-small cell lung carcinoma: an internet-based assessment of international current practices
    Kelly J Butnor
    Department of Pathology, University of Vermont Fletcher Allen Health Care, Burlington, VT 05401, USA
    Am J Clin Pathol 128:638-47. 2007
    ..However, the formation of internationally recognized guidelines for assessing VPI by NSCLC is likely to improve diagnostic consensus...
  28. ncbi request reprint Nitrogen dioxide enhances allergic airway inflammation and hyperresponsiveness in the mouse
    Matthew E Poynter
    Department of Medicine, University of Vermont, Burlington, VT 05405, USA
    Am J Physiol Lung Cell Mol Physiol 290:L144-52. 2006
    ..Collectively, these observations suggest an important role for NO2 in airway pathologies associated with asthma, both in modulation of degree and duration of inflammatory response, as well as in induction of AHR...
  29. pmc Linking parenchymal disease progression to changes in lung mechanical function by percolation
    Jason H T Bates
    Vermont Lung Center, University of Vermont College of Medicine, VT, USA
    Am J Respir Crit Care Med 176:617-23. 2007
    ..However, merely ascribing mechanical dysfunction of the parenchyma to the vagaries of lesional organization is unhelpful without some understanding of how the two are linked...
  30. ncbi request reprint Malignant mesothelioma and occupational exposure to asbestos: a clinicopathological correlation of 1445 cases
    Victor L Roggli
    Department of Pathology, Durham Veterans Administration and Duke University Medical Center, North Carolina 27710, USA
    Ultrastruct Pathol 26:55-65. 2002
    ..All but 1 of the occupational categories analyzed had above-background levels of commercial amphiboles. Commercial amphiboles are responsible for most of the mesothelioma cases observed in the United States...
  31. ncbi request reprint Malignant mesothelioma following thoracic radiotherapy for lung cancer
    Sabrina M Witherby
    Department of Medicine, University of Vermont College of Medicine, Vermont Cancer Center, 89 Beaumont Avenue, Given E 214, Burlington, VT 05405, USA
    Lung Cancer 57:410-3. 2007
    ..Secondary malignancies such as mesothelioma should be considered in patients who develop unexplained symptoms even long after treatment of a primary tumor...
  32. doi request reprint CT features of peripheral pulmonary carcinoid tumors
    Quinn Colin Meisinger
    Department of Radiology, University of Vermont College of Medicine, Burlington, VT 05401, USA
    AJR Am J Roentgenol 197:1073-80. 2011
    ....
  33. ncbi request reprint Spontaneous orbital and periocular hemorrhage in a patient with epithelioid hemangioma
    Daniel R Brooks
    College of Medicine, University of Vermont College of Medicine, Burlington, Vermont, USA
    Ophthal Plast Reconstr Surg 22:487-9. 2006
    ..Epithelioid hemangioma should be considered in the differential diagnosis for patients presenting with spontaneous orbital or periocular hemorrhage...
  34. ncbi request reprint A bronchoscopic oddity: nodular tracheobronchial amyloidosis
    Krish Bhadra
    Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pennsylvania, Philadelphia, PA and Department of Pathology Division of Pulmonary Disease and Critical Care Medicine, University of Vermont College of Medicine, Burlington, VT
    J Bronchology Interv Pulmonol 17:248-52. 2010
    ..Other treatment strategies include airway stenting, external beam radiation therapy, bypass tracheostomy, or open surgical resection...
  35. pmc NF-kappa B activation in airways modulates allergic inflammation but not hyperresponsiveness
    Matthew E Poynter
    Vermont Lung Center and the Department of Medicine, Division of Pulmonary and Critical Care, University of Vermont, Burlington, VT 05405, USA
    J Immunol 173:7003-9. 2004
    ....