J Bustillo

Summary

Affiliation: University of New Mexico
Country: USA

Publications

  1. ncbi request reprint High choline concentrations in the caudate nucleus in antipsychotic-naive patients with schizophrenia
    Juan R Bustillo
    Department of Psychiatry, University of New Mexico School of Medicine, 87131, USA
    Am J Psychiatry 159:130-3. 2002
  2. pmc Medial-frontal cortex hypometabolism in chronic phencyclidine exposed rats assessed by high resolution magic angle spin 11.7 T proton magnetic resonance spectroscopy
    Juan Bustillo
    Department of Psychiatry, University of New Mexico Health Sciences Center, Albuquerque, NM 87131, USA
    Neurochem Int 61:128-31. 2012
  3. pmc Glutamate as a marker of cognitive function in schizophrenia: a proton spectroscopic imaging study at 4 Tesla
    Juan R Bustillo
    Department of Psychiatry, University of New Mexico, Albuquerque, New Mexico, USA
    Biol Psychiatry 69:19-27. 2011
  4. pmc 1H-MRS at 4 tesla in minimally treated early schizophrenia
    J R Bustillo
    Department of Psychiatry, University of New Mexico, Albuquerque, NM 87131 0001, USA
    Mol Psychiatry 15:629-36. 2010
  5. ncbi request reprint Proton magnetic resonance spectroscopy during initial treatment with antipsychotic medication in schizophrenia
    Juan R Bustillo
    Department of Psychiatry, University of New Mexico, Albuquerque, NM 87131 0001, USA
    Neuropsychopharmacology 33:2456-66. 2008
  6. ncbi request reprint Long-term treatment of rats with haloperidol: lack of an effect on brain N-acetyl aspartate levels
    Juan Bustillo
    Department of Psychiatry, University of New Mexico Health Sciences Center, Albuquerque, NM 87131 0001, USA
    Neuropsychopharmacology 31:751-6. 2006
  7. ncbi request reprint The psychosocial treatment of schizophrenia: an update
    J Bustillo
    Department of Psychiatry, University of New Mexico School of Medicine, Albuquerque, NM 87131, USA
    Am J Psychiatry 158:163-75. 2001
  8. ncbi request reprint Treatment of weight gain with fluoxetine in olanzapine-treated schizophrenic outpatients
    Juan R Bustillo
    Department of Psychiatry, Research Division, 2400 Tucker NE, University of New Mexico, Albuquerque, NM 87131, USA
    Neuropsychopharmacology 28:527-9. 2003
  9. ncbi request reprint Effects of chronic haloperidol and clozapine treatments on frontal and caudate neurochemistry in schizophrenia
    J R Bustillo
    Department of Psychiatry, Research Division, University of New Mexico, 2400 Tucker NE, Albuquerque, NM 87131, USA
    Psychiatry Res 107:135-49. 2001
  10. ncbi request reprint Integrated treatment of schizophrenia
    Roshel Lenroot
    Department of Psychiatry, School of Medicine, University of New Mexico, 2400 Tucker NE, Albuquerque, NM 87131, USA
    Psychiatr Serv 54:1499-507. 2003

Research Grants

  1. Brain Glutamate and Outcome in Schizophrenia
    Juan R Bustillo; Fiscal Year: 2010

Detail Information

Publications15

  1. ncbi request reprint High choline concentrations in the caudate nucleus in antipsychotic-naive patients with schizophrenia
    Juan R Bustillo
    Department of Psychiatry, University of New Mexico School of Medicine, 87131, USA
    Am J Psychiatry 159:130-3. 2002
    ..Proton magnetic resonance spectroscopy ((1)H-MRS) studies of medicated patients with schizophrenia suggest high choline levels in the caudate nucleus. However, assessments of antipsychotic-naive patients are needed...
  2. pmc Medial-frontal cortex hypometabolism in chronic phencyclidine exposed rats assessed by high resolution magic angle spin 11.7 T proton magnetic resonance spectroscopy
    Juan Bustillo
    Department of Psychiatry, University of New Mexico Health Sciences Center, Albuquerque, NM 87131, USA
    Neurochem Int 61:128-31. 2012
    ....
  3. pmc Glutamate as a marker of cognitive function in schizophrenia: a proton spectroscopic imaging study at 4 Tesla
    Juan R Bustillo
    Department of Psychiatry, University of New Mexico, Albuquerque, New Mexico, USA
    Biol Psychiatry 69:19-27. 2011
    ..We examined the relationship between glutamate metabolism and cognitive function in schizophrenia...
  4. pmc 1H-MRS at 4 tesla in minimally treated early schizophrenia
    J R Bustillo
    Department of Psychiatry, University of New Mexico, Albuquerque, NM 87131 0001, USA
    Mol Psychiatry 15:629-36. 2010
    ..We conclude that early in the illness, schizophrenia patients already show abnormalities in glutamatergic metabolism and reductions in NAA consistent with glutamate-related excitotoxicity...
  5. ncbi request reprint Proton magnetic resonance spectroscopy during initial treatment with antipsychotic medication in schizophrenia
    Juan R Bustillo
    Department of Psychiatry, University of New Mexico, Albuquerque, NM 87131 0001, USA
    Neuropsychopharmacology 33:2456-66. 2008
    ..Early in the illness, schizophrenia patients already demonstrate subtle reductions in NAA. Treatment with typical or atypical antipsychotic medications for several months does not result in NAA changes...
  6. ncbi request reprint Long-term treatment of rats with haloperidol: lack of an effect on brain N-acetyl aspartate levels
    Juan Bustillo
    Department of Psychiatry, University of New Mexico Health Sciences Center, Albuquerque, NM 87131 0001, USA
    Neuropsychopharmacology 31:751-6. 2006
    ..The documented lower NAA in chronically treated schizophrenia patients is most likely not a simple effect of antipsychotic medications...
  7. ncbi request reprint The psychosocial treatment of schizophrenia: an update
    J Bustillo
    Department of Psychiatry, University of New Mexico School of Medicine, Albuquerque, NM 87131, USA
    Am J Psychiatry 158:163-75. 2001
    ..The authors sought to update the randomized controlled trial literature of psychosocial treatments for schizophrenia...
  8. ncbi request reprint Treatment of weight gain with fluoxetine in olanzapine-treated schizophrenic outpatients
    Juan R Bustillo
    Department of Psychiatry, Research Division, 2400 Tucker NE, University of New Mexico, Albuquerque, NM 87131, USA
    Neuropsychopharmacology 28:527-9. 2003
    ..Serotonin reuptake inhibitors are probably not a practical option to counteract weight gain induced by atypical antipsychotics. Atypical-induced weight gain may result from mechanisms other than 5HT reuptake blockade...
  9. ncbi request reprint Effects of chronic haloperidol and clozapine treatments on frontal and caudate neurochemistry in schizophrenia
    J R Bustillo
    Department of Psychiatry, Research Division, University of New Mexico, 2400 Tucker NE, Albuquerque, NM 87131, USA
    Psychiatry Res 107:135-49. 2001
    ..Exposure to haloperidol-like drugs may in part account for the frontal NAA reductions previously reported in schizophrenia. Adjustment for proportion of voxel CSF should be considered in 1H-MRS studies...
  10. ncbi request reprint Integrated treatment of schizophrenia
    Roshel Lenroot
    Department of Psychiatry, School of Medicine, University of New Mexico, 2400 Tucker NE, Albuquerque, NM 87131, USA
    Psychiatr Serv 54:1499-507. 2003
    ..Emphasis is placed on areas of interaction, including patient adherence and the effect of antipsychotic medications on cognitive functioning. Recommendations are presented for specific clinical situations...
  11. ncbi request reprint Maximizing the synergy between pharmacotherapy and psychosocial therapies for schizophrenia
    John Lauriello
    Department of Psychiatry, University of New Mexico, 2400 Tucker Avenue NE, Albuquerque, NM 87131, USA
    Psychiatr Clin North Am 26:191-211. 2003
    ....
  12. ncbi request reprint Longitudinal follow-up of neurochemical changes during the first year of antipsychotic treatment in schizophrenia patients with minimal previous medication exposure
    Juan R Bustillo
    Department of Psychiatry, Research Division, University of New Mexico, 2400 Tucker NE, Albuquerque, NM 87131, USA
    Schizophr Res 58:313-21. 2002
    ..The well-described reduced frontal NAA in schizophrenia may not be a trait of the illness but may represent medication effect or progression of the disease...
  13. pmc Antipsychotic dose and diminished neural modulation: a multi-site fMRI study
    C Abbott
    Dept of Psychiatry, University of New Mexico, Albuquerque, New Mexico 87131, United States
    Prog Neuropsychopharmacol Biol Psychiatry 35:473-82. 2011
    ..The purpose of the present investigation is to examine the effect of antipsychotic medication on independent neural networks during a motor task in a large, multi-site functional magnetic resonance imaging investigation...
  14. ncbi request reprint Effects of ketamine on anterior cingulate glutamate metabolism in healthy humans: a 4-T proton MRS study
    Laura M Rowland
    Department of Psychiatry, MIND Imaging Center, University of New Mexico, USA
    Am J Psychiatry 162:394-6. 2005
    ..The authors' goal was to test in humans the hypothesis that N-methyl-d-aspartate receptor (NMDAR) antagonism results in increased cortical glutamate activity, as proposed by the NMDAR hypofunction model of schizophrenia...
  15. ncbi request reprint Selective cognitive impairments associated with NMDA receptor blockade in humans
    Laura M Rowland
    Maryland Psychiatric Research Center, University of Maryland School of Medicine, Baltimore, MD 21228, USA
    Neuropsychopharmacology 30:633-9. 2005
    ..Impaired cognition is a core feature of schizophrenia. A better understanding of NMDA antagonism, its physiological and cognitive consequences, may provide improved models of psychosis and cognitive therapeutics...

Research Grants2

  1. Brain Glutamate and Outcome in Schizophrenia
    Juan R Bustillo; Fiscal Year: 2010
    ..This is an essential step towards being able to select groups of patients whom may benefit from drugs that modulate glutamate function. ..