Wylie Burke

Summary

Affiliation: University of Washington
Country: USA

Publications

  1. ncbi request reprint Personalized medicine in the era of genomics
    Wylie Burke
    Center for Genomics and Healthcare Equality and Department of Medical History and Ethics, University of Washington, Seattle, WA 98195, USA
    JAMA 298:1682-4. 2007
  2. ncbi request reprint Breast cancer risk communication: assessment of primary care physicians by standardized patients
    Julie O Culver
    Department of Bioethics and Humanities, University of Washington, Seattle, Washington 98195, USA
    Genet Med 11:735-41. 2009
  3. pmc Genetics researchers' and IRB professionals' attitudes toward genetic research review: a comparative analysis
    Karen L Edwards
    Department of Epidemiology, University of Washington, Seattle, WA, USA
    Genet Med 14:236-42. 2012
  4. pmc Family history assessment to detect increased risk for colorectal cancer: conceptual considerations and a preliminary economic analysis
    Scott D Ramsey
    Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North M2 B230, P O Box 19024, Seattle, WA 98109, USA
    Cancer Epidemiol Biomarkers Prev 14:2494-500. 2005
  5. pmc Stakeholder perspectives on a risk-benefit framework for genetic testing
    Joshua A Roth
    Department of Pharmacy, University of Washington, Seattle, WA 98195, USA
    Public Health Genomics 14:59-67. 2011
  6. ncbi request reprint Breast cancer risk counseling improves women's functioning
    Deborah J Bowen
    Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, MP 900, Seattle, WA 98109, USA
    Patient Educ Couns 53:79-86. 2004
  7. pmc Genetic assessment of breast cancer risk in primary care practice
    Wylie Burke
    Department of Bioethics and Humanities, University of Washington, Seattle, Washington 98195 7120, USA
    Am J Med Genet A 149:349-56. 2009
  8. pmc Return of incidental findings in genomic medicine: measuring what patients value--development of an instrument to measure preferences for information from next-generation testing (IMPRINT)
    Caroline Savage Bennette
    Department of Pharmacy, Pharmaceutical Outcomes Research and Policy Program, University of Washington, Seattle, Washington, USA
    Genet Med 15:873-81. 2013
  9. pmc Recommendations for returning genomic incidental findings? We need to talk!
    Wylie Burke
    Department of Bioethics and Humanities, University of Washington, Seattle, Washington, USA
    Genet Med 15:854-9. 2013
  10. pmc Debating clinical utility
    Wylie Burke
    Department of Bioethics and Humanities, University of Washington, Seattle, Wash 98195 7120, USA
    Public Health Genomics 13:215-23. 2010

Detail Information

Publications80

  1. ncbi request reprint Personalized medicine in the era of genomics
    Wylie Burke
    Center for Genomics and Healthcare Equality and Department of Medical History and Ethics, University of Washington, Seattle, WA 98195, USA
    JAMA 298:1682-4. 2007
  2. ncbi request reprint Breast cancer risk communication: assessment of primary care physicians by standardized patients
    Julie O Culver
    Department of Bioethics and Humanities, University of Washington, Seattle, Washington 98195, USA
    Genet Med 11:735-41. 2009
    ..To assess primary care providers' communication about breast cancer risk...
  3. pmc Genetics researchers' and IRB professionals' attitudes toward genetic research review: a comparative analysis
    Karen L Edwards
    Department of Epidemiology, University of Washington, Seattle, WA, USA
    Genet Med 14:236-42. 2012
    ..However, few empirical studies describe how genetic researchers and institutional review board (IRB) professionals conceptualize ethical issues in genetic research or where common ground might exist...
  4. pmc Family history assessment to detect increased risk for colorectal cancer: conceptual considerations and a preliminary economic analysis
    Scott D Ramsey
    Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North M2 B230, P O Box 19024, Seattle, WA 98109, USA
    Cancer Epidemiol Biomarkers Prev 14:2494-500. 2005
    ..Although the rationale for earlier screening of persons with a family history of colorectal cancer is plausible, there is no direct evidence that earlier assessment is either effective or cost-effective...
  5. pmc Stakeholder perspectives on a risk-benefit framework for genetic testing
    Joshua A Roth
    Department of Pharmacy, University of Washington, Seattle, WA 98195, USA
    Public Health Genomics 14:59-67. 2011
    ..The meeting's findings emphasize the potential utility of risk-benefit analysis in genetic test evaluation, and highlight key areas for future research and stakeholder consensus-building...
  6. ncbi request reprint Breast cancer risk counseling improves women's functioning
    Deborah J Bowen
    Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, MP 900, Seattle, WA 98109, USA
    Patient Educ Couns 53:79-86. 2004
    ..Cancer worry decreased in both counseling groups by one scale point (P < 0.05). These results indicate that counseling can relieve women's negative reactions to breast cancer risk...
  7. pmc Genetic assessment of breast cancer risk in primary care practice
    Wylie Burke
    Department of Bioethics and Humanities, University of Washington, Seattle, Washington 98195 7120, USA
    Am J Med Genet A 149:349-56. 2009
    ..Educational efforts may be most successful when they emphasize the value of genetic counseling for individuals at risk for inherited cancer and the connection between genetic risk and specific prevention measures...
  8. pmc Return of incidental findings in genomic medicine: measuring what patients value--development of an instrument to measure preferences for information from next-generation testing (IMPRINT)
    Caroline Savage Bennette
    Department of Pharmacy, Pharmaceutical Outcomes Research and Policy Program, University of Washington, Seattle, Washington, USA
    Genet Med 15:873-81. 2013
    ..This study identified attributes of incidental findings that were important to patients and developed a discrete-choice experiment instrument to quantify patient preferences...
  9. pmc Recommendations for returning genomic incidental findings? We need to talk!
    Wylie Burke
    Department of Bioethics and Humanities, University of Washington, Seattle, Washington, USA
    Genet Med 15:854-9. 2013
    ..Instead of premature practice recommendations, we call for robust dialogue among stakeholders to define a pathway to normatively sound, evidence-based guidelines...
  10. pmc Debating clinical utility
    Wylie Burke
    Department of Bioethics and Humanities, University of Washington, Seattle, Wash 98195 7120, USA
    Public Health Genomics 13:215-23. 2010
    ..Addressing each of these issues requires attention to stakeholder values and methods for effective deliberation that incorporate consumer as well as health professional perspectives...
  11. ncbi request reprint Effects of individual and family functioning on interest in genetic testing
    Deborah J Bowen
    Fred Hutchinson Cancer Research Center, Seattle, Wash 98109, USA
    Community Genet 7:25-32. 2004
    ..The present study reports on the important issue of how family communication and support regarding breast cancer risk affects interest in genetic testing and mental health...
  12. pmc Motivating factors for physician ordering of factor V Leiden genetic tests
    Lucia A Hindorff
    Department of Epidemiology, University of Washington, Seattle, USA
    Arch Intern Med 169:68-74. 2009
    ..The factor V Leiden (FVL) genetic test is used by many physicians despite its uncertain clinical utility...
  13. ncbi request reprint Effects of counseling Ashkenazi Jewish women about breast cancer risk
    Deborah J Bowen
    Department of Health Services, University of Washington, Seattle, WA 98109, USA
    Cultur Divers Ethnic Minor Psychol 12:45-56. 2006
    ..Counseling can help women gain a more accurate perception of their risk, expose them to the benefits and limitations of genetic testing, and reduce their worry about cancer...
  14. pmc Population description and its role in the interpretation of genetic association
    Stephanie M Fullerton
    Department of Bioethics and Humanities, Center for Genomics and Healthcare Equality, University of Washington School of Medicine, Box 357120, Seattle, WA 98195, USA
    Hum Genet 127:563-72. 2010
    ..Instead, criteria which help investigators better distinguish justified and unjustified forms of population generalization may be required...
  15. pmc Will knowledge of gene-based colorectal cancer disease risk influence quality of life and screening behavior? Findings from a population-based study
    Scott Ramsey
    Fred Hutchinson Cancer Research Center, University of Washington, Seattle, Wash 98109, USA
    Public Health Genomics 13:1-12. 2010
    ..We evaluated the potential impact of hypothetical colorectal-cancer-associated gene variant testing on quality of life, health habits and cancer screening behavior...
  16. pmc Translational genomics: seeking a shared vision of benefit
    Wylie Burke
    Department of Medical History and Ethics, University of Washington, Seattle, WA 98195, USA
    Am J Bioeth 8:54-6; discussion W1-3. 2008
  17. pmc Return of individual research results from genome-wide association studies: experience of the Electronic Medical Records and Genomics (eMERGE) Network
    Stephanie M Fullerton
    University of Washington, Seattle, Washington, USA
    Genet Med 14:424-31. 2012
    ..However, few groups have deliberated on specific results or weighed deliberations against relevant local contextual factors...
  18. pmc A formal risk-benefit framework for genomic tests: facilitating the appropriate translation of genomics into clinical practice
    David L Veenstra
    Department of Pharmacy, University of Washington, Seattle, Washington 98195, USA
    Genet Med 12:686-93. 2010
    ..To address these issues, this study presents a risk-benefit framework for assessing the health-related utility of genomic tests...
  19. ncbi request reprint Pharmacogenomic testing to prevent aminoglycoside-induced hearing loss in cystic fibrosis patients: potential impact on clinical, patient, and economic outcomes
    David L Veenstra
    Institute for Public Health Genetics, Department of Pharmacy, University of Washington, Seattle, Washington 98195, USA
    Genet Med 9:695-704. 2007
    ..Although the A1555G variant is very rare, it seems to confer a high risk of severe hearing loss in patients exposed to aminoglycosides...
  20. ncbi request reprint Ethical obligations and counseling challenges in cancer genetics
    Wylie Burke
    Department of Medical History and Ethics, University of Washington, Box 356120, 1959 NE Pacific, Room A204, Seattle, WA 98195 7120, USA
    J Natl Compr Canc Netw 4:185-91. 2006
    ..Clinicians must also provide emotional support and accurate information about cancer risks and cancer risk reduction measures, including uncertainties. Teamwork among different specialties is important in addressing these challenges...
  21. ncbi request reprint Practicing moral medicine: patient care to public health
    Denise M Dudzinski
    University of Washington, USA
    Am J Bioeth 6:75-6. 2006
  22. ncbi request reprint Contributions of public health to genetics education for health care professionals
    Wylie Burke
    Department of Medical History and Ethics, University of Washington, Seattle, WA 98195 7120, USA
    Health Educ Behav 32:668-75. 2005
    ....
  23. ncbi request reprint Genetics as a tool to improve cancer outcomes: ethics and policy
    Wylie Burke
    Department of Medical History and Ethics, University of Washington, Box 357120, 1959 North East Pacific, Room A204, Seattle, Washington 98195 7120, USA
    Nat Rev Cancer 6:476-82. 2006
    ..When the benefits of testing are well established, efforts must also be made to ensure access to genetic services for all who can benefit...
  24. pmc Genetic screening
    Wylie Burke
    Department of Bioethics and Humanities, A204 Health Sciences Building, Box 357120, University of Washington, Seattle, WA 98195, USA
    Epidemiol Rev 33:148-64. 2011
    ....
  25. ncbi request reprint The path from genome-based research to population health: development of an international public health genomics network
    Wylie Burke
    Department of Medical History and Ethics, University of Washington, Seattle, WA 98195 7120, USA
    Genet Med 8:451-8. 2006
  26. pmc Use of Factor V Leiden genetic testing in practice and impact on management
    Anne Marie Laberge
    Institute for Public Health Genetics, Center for Genomics and Healthcare Equality, University of Washington, Seattle, Washington, USA
    Genet Med 11:750-6. 2009
    ..To assess the use of the genetic test for Factor V Leiden in clinical practice, physician adherence to national and local guidelines, and impacts of test results on patient management...
  27. doi request reprint Extending the reach of public health genomics: what should be the agenda for public health in an era of genome-based and “personalized” medicine?
    Wylie Burke
    Department of Bioethics and Humanities, University of Washington, Seattle, Washington, USA
    Genet Med 12:785-91. 2010
    ..These deliberations formed the basis for six key recommendations, which could guide the practice of public health in an era of genomics and personalized medicine...
  28. pmc Genomic research and wide data sharing: views of prospective participants
    Susan Brown Trinidad
    Department of Bioethics and Humanities, University of Washington, Seattle, WA 98195 7120, USA
    Genet Med 12:486-95. 2010
    ..This study was designed to explore the perceptions, beliefs, and attitudes of research participants and possible future participants regarding genome-wide association studies and repository-based research...
  29. pmc Researcher perspectives on disclosure of incidental findings in genetic research
    Meredith C Meacham
    University of Washington s Institute of Public Health Genetics Master of Public Health program, Seattle, WA 98195 7120, USA
    J Empir Res Hum Res Ethics 5:31-41. 2010
    ....
  30. ncbi request reprint Return of genomic results to research participants: the floor, the ceiling, and the choices in between
    Gail P Jarvik
    Division of Medical Genetics, Department of Medicine, University of Washington, Seattle, WA 98195, USA Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA Electronic address
    Am J Hum Genet 94:818-26. 2014
    ..These positions are consistent with the recognition that clinical research is distinct from medical care in both its aims and its guiding moral principles. ..
  31. doi request reprint Clinical validity and clinical utility of genetic tests
    Wylie Burke
    University of Washington, Seattle, Washington, USA
    Curr Protoc Hum Genet . 2009
    ..This unit defines clinical validity and clinical utility, provides examples, and considers the implications of these test properties for clinical practice...
  32. ncbi request reprint Genetic information: Special or not? Responses from focus groups with members of a health maintenance organization
    Brenda Diergaarde
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
    Am J Med Genet A 143:564-9. 2007
    ..These data may guide future research and policy concerning the use and protection of medical information, including genetic information...
  33. ncbi request reprint Incorporating principles and practical wisdom in research ethics education: a preliminary study
    Nicole Deming
    Department of Medical History and Ethics, University of Washington School of Medicine, Seattle, WA 98195 7120, USA
    Acad Med 82:18-23. 2007
    ..This study characterized researchers' responses to ethical dilemmas with the goal of aligning research ethics education programs with the demands of practice...
  34. doi request reprint Clinical validity and clinical utility of genetic tests
    Wylie Burke
    University of Washington, Seattle, Washington, USA
    Curr Protoc Hum Genet . 2004
    ..This unit defines clinical validity and clinical utility, provides examples, and considers the implications of these test properties for clinical practice...
  35. ncbi request reprint Potential for genetics to promote public health: genetics research on smoking suggests caution about expectations
    Chris Carlsten
    Department of Medicine, Division of Pulmonary and Critical Care Medicine, Occupational and Environmental Medicine Program, University of Washington, Seattle, USA
    JAMA 296:2480-2. 2006
  36. doi request reprint Educational needs in genetic medicine: primary care perspectives
    Susan B Trinidad
    Department of Medical History and Ethics, University of Washington, Seattle, Wash 98195 7120, USA
    Community Genet 11:160-5. 2008
    ..This study was performed to identify primary care physicians' (PCPs) attitudes toward genetic medicine and their perceived needs for education in this area...
  37. ncbi request reprint Genetic testing in primary care
    Wylie Burke
    Department of Medical History and Ethics, University of Washington, Seattle, Washington 98195 7120, USA
    Annu Rev Genomics Hum Genet 5:1-14. 2004
    ..A partnership between medical genetics and primary care will help to ensure the development of effective policies, educational tools, and practice guidelines for the coming era of genomic health care...
  38. ncbi request reprint Jewish identity and intentions to obtain breast cancer screening
    Deborah J Bowen
    Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, MP900, Seattle, Washington 98109, USA
    Cultur Divers Ethnic Minor Psychol 9:79-87. 2003
    ..Religious identity was a significant predictor of intention to adhere to mammography recommendations. Findings show that culture and religion, although correlated, may have different associations with health attitudes...
  39. ncbi request reprint Achieving utility with family history: colorectal cancer risk
    Deborah J Bowen
    Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue N, MP900, Seattle, WA 98109, USA
    Am J Prev Med 24:177-82. 2003
    ..Where available, we cite data to support the issues that could arise. Where there are no studies, we invite further research. The potential of family history as a health improvement tool is still under review...
  40. ncbi request reprint Gene expression profiling and breast cancer care: what are the potential benefits and policy implications?
    Nina Oestreicher
    University of Washington, Seattle, Washington, USA
    Genet Med 7:380-9. 2005
    ..However, the outcomes associated with gene expression profiling are not clear, and guidelines for the appropriate use of genomic technologies have not been established...
  41. ncbi request reprint Defining purpose: a key step in genetic test evaluation
    Wylie Burke
    Department of Medical History and Ethics, University of Washington, Seattle, Washington 98195 7120, USA
    Genet Med 9:675-81. 2007
  42. ncbi request reprint Effects of risk counseling on interest in breast cancer genetic testing for lower risk women
    Deborah J Bowen
    Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
    Genet Med 4:359-65. 2002
    ..A randomized trial was conducted to test the effects of two counseling methods (genetic counseling and group counseling) against a control no-intervention condition on interest in genetic testing in lower risk women...
  43. ncbi request reprint Ethical issues arising from the participation of children in genetic research
    Wylie Burke
    Department of Medical History and Ethics, University of Washington, Seattle 98195 7120, USA
    J Pediatr 149:S34-8. 2006
    ..Because genetic information is often accorded special power in our society, careful attention should be paid to how genetic information is collected and used in research involving pediatric participants...
  44. pmc Trends in death associated with pediatric dental sedation and general anesthesia
    Helen H Lee
    Department of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA 98105, USA
    Paediatr Anaesth 23:741-6. 2013
    ..Sedation is increasingly popular and viewed as lower risk than GA in community settings. Currently, few data are available to quantify pediatric morbidity and mortality related to dental anesthesia...
  45. pmc Actionable, pathogenic incidental findings in 1,000 participants' exomes
    Michael O Dorschner
    Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA 98195, USA Department of Laboratory Medicine, University of Washington, Seattle, WA 98195, USA
    Am J Hum Genet 93:631-40. 2013
    ....
  46. ncbi request reprint Genomics as a probe for disease biology
    Wylie Burke
    Department of Medical History and Ethics, University of Washington, Seattle 98195, USA
    N Engl J Med 349:969-74. 2003
  47. pmc The asthma consultative process: a collaborative approach to integrating genomics into public health practice
    Tabitha A Harrison
    Department of Epidemiology, School of Public Health and Community Medicine, University of Washington, Seattle, WA 98105, USA
    Prev Chronic Dis 2:A27. 2005
    ..This paper describes the methods used to conduct these professional and community consultations, referred to as the asthma consultative process, and discusses the lessons learned from this activity...
  48. ncbi request reprint Ensuring the appropriate use of genetic tests
    Wylie Burke
    Department of Medical History and Ethics, Box 357120, University of Washington, 1959 NE Pacific, Room A204, Seattle, Washington 98195, USA
    Nat Rev Genet 5:955-9. 2004
    ..Other strategies, including resource allocation and matters related to clinical governance - such as practice-guideline development and health-provider education - are also important...
  49. ncbi request reprint Genetic testing
    Wylie Burke
    Department of Medical History and Ethics, University of Washington, Seattle, WA 98195, USA
    N Engl J Med 347:1867-75. 2002
  50. pmc Essential elements of personalized medicine
    Wylie Burke
    Department of Bioethics and Humanities, University of Washington, Seattle, WA Electronic address
    Urol Oncol 32:193-7. 2014
    ..Genomic information has been promoted as the basis for "personalized" health care. We considered the benefits provided by genomic testing in context of the concept of personalized medicine...
  51. doi request reprint Cytochrome p450 enzyme polymorphism frequency in indigenous and native american populations: a systematic review
    Cheedy Jaja
    Center for Genomics and Healthcare Equality, University of Washington, Seattle, Wash, USA
    Community Genet 11:141-9. 2008
    ..The purpose of our study was to evaluate the evidence on the prevalence of cytochrome P450 enzyme polymorphisms as potential genetic factors influencing drug efficacy and safety in the indigenous populations of the American hemispheres...
  52. pmc Systems medicine and the public's health
    Wylie Burke
    Department of Bioethics and Humanities, University of Washington, Box 357120, 1959 NE Pacific, Room A204, Seattle, WA 98195 7120, USA
    Genome Med 3:47. 2011
    ..See correspondence article: http://genomemedicine.com/content/3/7/43...
  53. pmc An economic viewpoint on alternative strategies for identifying persons with hereditary nonpolyposis colorectal cancer
    Scott D Ramsey
    Fred Hutchinson Cancer Research Center, and Department of Medicine, University of Washington, Seattle, Washington, USA
    Genet Med 5:353-63. 2003
    ..There is uncertainty regarding the optimal strategy for identifying mutation carriers among those with hereditary nonpolyposis colorectal cancer (HNPCC)...
  54. ncbi request reprint Genetic test evaluation: information needs of clinicians, policy makers, and the public
    Wylie Burke
    University of Washington, Seattle, WA, USA
    Am J Epidemiol 156:311-8. 2002
    ....
  55. ncbi request reprint Pharmacogenetic testing: not as simple as it seems
    Susanne B Haga
    Institute for Genome Sciences and Policy, Duke University, Durham, North Carolina27708, USA
    Genet Med 10:391-5. 2008
    ..These issues have implications for informed consent and genetic counseling requirements, and for the role of health professionals...
  56. ncbi request reprint Family history as a predictor of asthma risk
    Wylie Burke
    Department of Medical History and Ethics, University of Washington, Box 357120, 1959 NE Pacific, Seattle, WA 98195, USA
    Am J Prev Med 24:160-9. 2003
    ..Positive family history may have utility in targeting some individual prevention efforts, but the low positive predictive value limits its value as a means to direct environmental remediation efforts...
  57. ncbi request reprint Hereditary hemochromatosis: perspectives of public health, medical genetics, and primary care
    Giuseppina Imperatore
    National Canter for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
    Genet Med 5:1-8. 2003
    ..The authors review these data and consider their implications for public health, medical genetics, and primary care...
  58. ncbi request reprint Re: On the use of familial aggregation in population-based case probands for calculating penetrance
    Wylie Burke
    J Natl Cancer Inst 95:78-9. 2003
  59. ncbi request reprint Hereditary haemochromatosis: a realistic approach to prevention of iron overload disease in the population
    Wylie Burke
    Department of Medical History and Ethics, Box 357120, University of Washington, 1959 NE Pacific, Room A204, Seattle, WA 98195, USA
    Best Pract Res Clin Haematol 15:315-28. 2002
    ....
  60. pmc Reconsidering the family history in primary care
    Eugene C Rich
    Department of Medicine, Creighton University, 601 N 30th Street, Suite 8850, Omaha, NE 68131, USA
    J Gen Intern Med 19:273-80. 2004
    ....
  61. pmc Hereditary diffuse gastric cancer: association with lobular breast cancer
    Kasmintan A Schrader
    Department of Pathology and Laboratory Medicine, University of British Columbia, British Columbia Cancer Agency, Vancouver, BC, Canada
    Fam Cancer 7:73-82. 2008
    ....
  62. ncbi request reprint Anticipating dissemination of cancer genomics in public health: a theoretical approach to psychosocial and behavioral challenges
    Jennifer L Hay
    Memorial Sloan Kettering Cancer Center, Department of Psychiatry and Behavioral Sciences, New York, NY 10022, USA
    Ann Behav Med 34:275-86. 2007
    ..Given the recent sequencing of the human genome, genetic susceptibility information will probably be increasingly useful in the prevention and control of many common diseases, including cancer...
  63. ncbi request reprint Genetics education for primary-care providers
    Wylie Burke
    Department of Medical History and Ethics, University of Washington, Seattle, Washington 98195, USA
    Nat Rev Genet 3:561-6. 2002
    ..Although most have little knowledge of genetics, their expertise in the prudent use of technology is relevant to the task. Successful educational programmes will need to forge partnerships between primary care and genetics...
  64. doi request reprint Waiving informed consent in newborn screening research: balancing social value and respect
    Beth A Tarini
    Division of Pediatrics, University of Michigan, Ann Arbor, MI 48109, USA
    Am J Med Genet C Semin Med Genet 148:23-30. 2008
    ....
  65. pmc Differential use of available genetic tests among primary care physicians in the United States: results of a national survey
    Alexandra E Shields
    Harvard MGH Center on Genomics, Vulnerable Populations, and Health Disparities, Massachusetts General Hospital Partners HealthCare, Boston, Massachusetts, USA
    Genet Med 10:404-14. 2008
    ..This study assesses primary care physicians' experience ordering and referring patients for genetic testing, and whether minority-serving physicians are less likely than those serving fewer minorities to offer such services...
  66. ncbi request reprint Deliberate deceit of family members: a challenge to providers of clinical genetics services
    Jennifer T Loud
    Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services Food and Drug Administration, Rockville, MD 20853 7231, USA
    J Clin Oncol 24:1643-6. 2006
  67. pmc Diabetes and HFE mutations: cause or coincidence?
    Linda E Pinsky
    Department of Medicine, Division of General Internal Medicine, University of Washington Medical Center, 4245 Roosevelt Way, NE Seattle, WA 98105 6920, USA
    West J Med 176:114-5. 2002
  68. ncbi request reprint Ethical issues in identifying and recruiting participants for familial genetic research
    Laura M Beskow
    Department of Health Policy and Administration, University of North Carolina at Chapel Hill School of Public Health, Chapel Hill, NC 27599 7411, USA
    Am J Med Genet A 130:424-31. 2004
    ..They suggest a framework for considering alternative recruitment strategies and their implications, as well as highlight areas in need of further empirical research...
  69. ncbi request reprint Recommendations for the care of individuals with an inherited predisposition to Lynch syndrome: a systematic review
    Noralane M Lindor
    Department of Medical Genetics, Mayo Clinic College of Medicine, Rochester, Minn, USA
    JAMA 296:1507-17. 2006
    ..Potential risk-reducing interventions are recommended for individuals known to have these mutations...
  70. ncbi request reprint Will genomics widen or help heal the schism between medicine and public health?
    Muin J Khoury
    National Office of Public Health Genomics, Centers for Disease Control and Prevention, 4770 Buford Highway NE, Atlanta, GA 30341, USA
    Am J Prev Med 33:310-7. 2007
    ..A strong medicine-public health partnership in the genomics era is needed for the translation of all scientific discoveries for the benefit of population health...
  71. ncbi request reprint Adding pharmacogenetics information to drug labels: lessons learned
    Susanne B Haga
    Institute for Genome Sciences and Policy, Duke University, Durham, North Carolina 27708, USA
    Pharmacogenet Genomics 16:847-54. 2006
    ..We review the reasons behind the cautious label changes and discuss some of the lessons that can be learned from these experiences...
  72. ncbi request reprint Taking family history seriously
    Wylie Burke
    Ann Intern Med 143:388-9. 2005
  73. ncbi request reprint American Cancer Society guidelines for breast screening with MRI as an adjunct to mammography
    Debbie Saslow
    Cancer Control Science Department, American Cancer Society, Atlanta, GA, USA
    CA Cancer J Clin 57:75-89. 2007
    ..Diagnostic uses of MRI were not considered to be within the scope of this review...
  74. ncbi request reprint Changing the clinical management of hereditary hemochromatosis: translating screening and early case detection strategies into clinical practice
    Alexander R Hover
    St John s Regional Health Center, St John s Health System, Springfield, MO 65804, USA
    Arch Intern Med 164:957-61. 2004
    ..This article describes the effect of an extensive physician educational program on detection and management of hereditary hemochromatosis (HH) before and after a hemochromatosis population screening study...
  75. ncbi request reprint ASHG Statement* on direct-to-consumer genetic testing in the United States
    Kathy Hudson
    Department of Pediatrics, Johns Hopkins University, Washington, D C, USA
    Obstet Gynecol 110:1392-5. 2007
  76. ncbi request reprint 'That's like chopping off a finger because you're afraid it might get broken': disease and illness in women's views of prophylactic mastectomy
    Nancy Press
    Schools of Nursing and Medicine, Oregon Health and Science University, 3455 SW US Veterans Hospital Road, SN 5S, Portland, OR 97239 2941, USA
    Soc Sci Med 61:1106-17. 2005
    ..We suggest that while prophylactic mastectomy may prevent the "disease" of breast cancer, it may be of little interest to women who see this surgery as itself mimicking the "illness" of breast cancer...
  77. ncbi request reprint Genetic exceptionalism. Too much of a good thing?
    James P Evans
    Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599 7264, USA
    Genet Med 10:500-1. 2008
  78. ncbi request reprint Genomic profiling to promote a healthy lifestyle: not ready for prime time
    Susanne B Haga
    Center for the Advancement of Genomics, 1901 Research Blvd, Sixth Floor, Rockville, Maryland 20850, USA
    Nat Genet 34:347-50. 2003
  79. ncbi request reprint Using pharmacogenetics to improve drug safety and efficacy
    Susanne B Haga
    The Center for the Advancement of Genomics, Rockville, MD, USA
    JAMA 291:2869-71. 2004
  80. ncbi request reprint Genetic risk in context: calculating the penetrance of BRCA1 and BRCA2 mutations
    Wylie Burke
    J Natl Cancer Inst 94:1185-7. 2002