Research Topics
| L BurdSummaryAffiliation: University of North Dakota Country: USA Publications
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Publications
The attention-deficit hyperactivity disorder paradox: 2. Phenotypic variability in prevalence and cost of comorbidityLarry Burd
Department of Pediatrics, University of North Dakota School of Medicine, North Dakota Population Health Laboratory, Grand Forks, ND, USA
J Child Neurol 18:653-60. 2003..We identified an ADHD paradox: decreased rates of comorbid general health conditions and increased rates of comorbid mental disorders. Further research on comorbidity in ADHD is required...
Ethanol and the placenta: A reviewLarry Burd
Department of Pediatrics, University of North Dakota School of Medicine and Health Sciences, Grand Forks, North Dakota, USA
J Matern Fetal Neonatal Med 20:361-75. 2007..In this paper we review published studies of alcohol exposure on placentation, placenta growth and function...
Fetal alcohol syndrome: neuropsychiatric phenomicsLarry Burd
North Dakota Fetal Alcohol Syndrome Center, Department of Pediatrics, University of North Dakota School of Medicine, 1300 S Columbia Road, Grand Forks, ND 58202, USA
Neurotoxicol Teratol 25:697-705. 2003..Adults will require care primarily from teams with expertise in mental health and developmental disabilities...
Fetal, infant, and child mortality in a context of alcohol useLarry Burd
North Dakota Fetal Alcohol Syndrome Center, University of North Dakota School of Medicine and Health Sciences, 501 North Columbia Road, Grand Rapids, ND 58203, USA
Am J Med Genet C Semin Med Genet 127:51-8. 2004..A schema to collect data on alcohol use is provided to increase awareness of alcohol use as an environmental risk marker for mortality...
Diagnosis of FAS: a comparison of the Fetal Alcohol Syndrome Diagnostic Checklist and the Institute of Medicine Criteria for Fetal Alcohol SyndromeLarry Burd
North Dakota Fetal Alcohol Syndrome Center, Department of Pediatrics, School of Medicine and Health Sciences, University of North Dakota, 501 North Columbia Road, Grand Forks, ND 58203, USA
Neurotoxicol Teratol 25:719-24. 2003..The syndrome may be more common than has been previously reported. Considerable controversy exists over the approaches for diagnosis of the syndrome...
Efficacy of a SIDS risk factor education methodology at a native American and Caucasian siteLarry Burd
ND Fetal Alcohol Syndrome Center, University of North Dakota School of Medicine and Health Sciences, Grand Forks, ND 58203, USA
Matern Child Health J 11:365-71. 2007..To complete a community based efficacy study of a SIDS risk reduction methodology...
A staged screening strategy for prenatal alcohol exposure and maternal risk stratificationLarry Burd
Department of Pediatrics, University of North Dakota School of Medicine and Health Sciences, 501 N Columbia Road, Grand Forks, ND 58203, USA
J R Soc Promot Health 126:86-94. 2006..We include an illustrative example of the development of a screening component using an existing data set...
Tourette Syndrome and learning disabilitiesLarry Burd
Department of Pediatrics, University of North Dakota School of Medicine and Health Sciences, Grand Forks, North Dakota, USA
BMC Pediatr 5:34. 2005..Learning disabilities are frequently comorbid with TS. Using the largest sample of TS patients ever reported, we sought to identify differences between subjects with TS only and subjects with TS and a comorbid learning disability...
Increased sibling mortality in children with fetal alcohol syndromeLarry Burd
Department of Pediatrics, University of North Dakota, Grand Forks, ND 58203, USA
Addict Biol 9:179-86; discussion 187-8. 2004..Maternal alcoholism appears to be a useful risk marker for increased mortality risk in diagnosed cases and their siblings. This has important implications in the management of family members of children with FAS...
Fetal alcohol syndrome. IntroductionLarry Burd
Fetal Alcohol Syndrome Center, Department of Pediatrics, University of North Dakota, Grand Forks, ND 58203, USA
Addict Biol 9:115-8. 2004
Recognition and management of fetal alcohol syndromeLarry Burd
Department of Pediatrics, University of North Dakota School of Medicine and Health Sciences, Grand Forks, ND 58202 9037, USA
Neurotoxicol Teratol 25:681-8. 2003..0 billion. Early recognition and entry into appropriate treatment programs appear to improve outcome. Prevention efforts should involve screening for alcohol use prior to pregnancy and at the first prenatal care visit...
Prenatal alcohol exposure assessment: multiple embedded measures in a prenatal questionnaireLarry Burd
North Dakota Fetal Alcohol Syndrome Center, School of Medicine and the Health Sciences, University of North Dakota, 501 N Columbia Road, Grand Forks, ND 58203, USA
Neurotoxicol Teratol 25:675-9. 2003..The data from prenatal care can also be used for maternal risk stratification. Early identification can provide opportunity for early interventions to decrease total exposure during pregnancy and to improve the outcome for the child...
Congenital heart defects and fetal alcohol spectrum disordersLarry Burd
Department of Pediatrics, Univrsity of North Dakota School of Medicine and Health Sciences, Grand Forks, ND 58203, USA
Congenit Heart Dis 2:250-5. 2007..Review of the prevalence of congenital heart defects (CHD) and fetal alcohol spectrum disorder (FASD)...
Diagnosis of fetal alcohol spectrum disorders: a validity study of the fetal alcohol syndrome checklistLarry Burd
Department of Pediatrics, North Dakota Fetal Alcohol Syndrome Center, University of North Dakota School of Medicine and Health Sciences, Grand Forks, ND 58203, USA
Alcohol 44:605-14. 2010..The FASDC scores produce diagnostic groupings that approximate expert clinical judgment. The tool may be useful in other clinical settings for the diagnosis of FASD or as an FASD registry or research database...
Long-term follow-up of an epidemiologically defined cohort of patients with Tourette syndromeL Burd
Department of Neuroscience, University of North Dakota School of Medicine and Health Sciences, Grand Forks, USA
J Child Neurol 16:431-7. 2001..Males demonstrated substantially more variability in improvement but overall demonstrated more improvement than females...
Neuropsychiatric genetics: misclassification in linkage studies of phenotype-genotype researchL Burd
Department of Pediatrics, University of North Dakota School of Medicine, Grand Forks, USA
J Child Neurol 16:499-504. 2001..The model demonstrates that an error rate of 5% would result in misclassification of 20% of true cases by step three. Adding additional steps to improve diagnostic accuracy may increase rather than decrease classification error...
Tourette syndrome and comorbid pervasive developmental disordersLarry Burd
Department of Pediatrics, University of North Dakota School of Medicine and Health Sciences, Grand Forks, North Dakota 58202 9037, USA
J Child Neurol 24:170-5. 2009..Identification of differences between subgroups of patients with Tourette syndrome may increase understanding of syndromal susceptibility, severity, and outcome...
Prospective long-term follow-up of patients with pervasive developmental disordersLarry Burd
Department of Pediatrics, University of North Dakota School of Medicine and Health Sciences, Grand Forks, ND, USA
J Child Neurol 17:681-8. 2002..Male subjects demonstrated substantially more variability in improvement but, overall, demonstrated more improvement than female subjects...
Biomarkers for detection of prenatal alcohol exposure: a critical review of fatty acid ethyl esters in meconiumLarry Burd
North Dakota Fetal Alcohol Syndrome Center, Department of Pediatrics, University of North Dakota School of Medicine and Health Sciences, Grand Forks, North Dakota 58203 9037, USA
Birth Defects Res A Clin Mol Teratol 82:487-93. 2008..The objective of this study was a review of published studies utilizing measurement of fatty acid ethyl esters (FAEE) in meconium as biomarkers for prenatal alcohol exposure...
Children and adolescents with attention deficit-hyperactivity disorder: 1. Prevalence and cost of careLarry Burd
Department of Pediatrics, University of North Dakota School of Medicine, and the North Dakota Population Health Laboratory, Grand Forks, ND, USA
J Child Neurol 18:555-61. 2003..79 million dollars. Thus, 1.9% of total health expenditures for children was attributable to ADHD. In the United States, the cost of care attributable to children with ADHD would be 2.15 billion dollars annually...
Fetal alcohol syndrome in the United States corrections systemLarry Burd
The North Dakota Fetal Alcohol Syndrome Center, University of North Dakota School of Medicine and Health Sciences, Grand Forks, ND 58203, USA
Addict Biol 9:169-76; discussion 177-8. 2004..Reported staff training needs were very large. In conclusion, corrections systems have high unmet needs to screen, identify, and treat offenders with FAS and ARND. Staff training needs are substantial...
Prenatal and perinatal risk factors for Tourette disorderL Burd
Department of Pediatrics and Neuroscience, University of North Dakota School of Medicine and Health Sciences, USA
J Perinat Med 27:295-302. 1999..To identify pre- and perinatal risk factors for Tourette disorder...
Prenatal and perinatal risk factors for autismL Burd
University of North Dakota School of Medicine and Health Sciences, North Dakota Fetal Alcohol Syndrome Center, Grand Forks, USA
J Perinat Med 27:441-50. 1999..To identify pre- and perinatal risk factors for autism...
A comparison of the effects of parental risk markers on pre- and perinatal variables in multiple patient cohorts with fetal alcohol syndrome, autism, Tourette syndrome, and sudden infant death syndrome: an enviromic analysisMarilyn G Klug
North Dakota Fetal Alcohol Syndrome Center, School of Medicine and Health Sciences, University of North Dakota, Box 9037, 501 N. Columbia Road, Grand Forks, ND 58202-9037, USA
Neurotoxicol Teratol 25:707-17. 2003..Use of cohorts from similar denominator populations obtained from prevalence studies is a useful methodological tool for estimating the prevalence and magnitude of effect of risk markers...
Prenatal alcohol exposure, blood alcohol concentrations and alcohol elimination rates for the mother, fetus and newbornL Burd
North Dakota Fetal Alcohol Syndrome Center, Department of Pediatrics, University of North Dakota School of Medicine and Health Sciences, Grand Forks, ND 58203, USA
J Perinatol 32:652-9. 2012..Lastly, detection of alcohol use and appropriate management would decrease risk from PAE for subsequent pregnancies...
Epidemiology of fetal alcohol syndrome in American Indians, Alaskan Natives, and Canadian Aboriginal peoples: a review of the literatureL Burd
Department of Pediatrics, University of North Dakota, School of Medicine, Grand Forks
Public Health Rep 109:688-93. 1994..Reviews of death certificates may also bea potentially important source of cases...
Tourette syndrome and comorbid early-onset schizophreniaJacob Kerbeshian
Department of Neuroscience, University of North Dakota School of Medicine and Health Sciences, Grand Forks, ND 58202 9037, USA
J Psychosom Res 67:515-23. 2009..A study of the shared phenomenology between Tourette syndrome (TS) and schizophrenia...
Mortality rates in subjects with fetal alcohol spectrum disorders and their siblingsLarry Burd
University of North Dakota School of Medicine and Health Sciences, Department of Pediatrics, Grand Forks, North Dakota 58203
Birth Defects Res A Clin Mol Teratol 82:217-23. 2008..Our objective was to estimate the mortality rate in subjects with fetal alcohol spectrum disorders (FASD) and their siblings whose FASD status was unknown...
Is anorexia nervosa a neuropsychiatric developmental disorder? An illustrative case reportJacob Kerbeshian
Department of Neuroscience, University of North Dakota School of Medicine and Health Sciences, Grand Forks, ND, USA
World J Biol Psychiatry 10:648-57. 2009..We conclude with examples of a neuropsychiatric developmental approach to generate a research agenda for anorexia nervosa...
A 15-year follow-up of a boy with pyridoxine (vitamin B6)-dependent seizures with autism, breath holding, and severe mental retardationL Burd
Department of Pediatrics, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, USA
J Child Neurol 15:763-5. 2000..This complex outcome should alert clinicians to the wide range of neuropsychiatric outcomes associated with this disorder...
Health care costs and utilization rates for children with pervasive developmental disorders in North Dakota from 1998 to 2004: impact on MedicaidChun Zi Peng
Department of Pediatrics, University of North Dakota School of Medicine and Health Sciences, Grand Forks, North Dakota 58202 9037, USA
J Child Neurol 24:140-7. 2009..4:1), and pharmacy services ($1258 vs $82, ratio = 15:1). Children with pervasive developmental disorders covered by Medicaid have increased costs of health care...
Impact of smoking on cancer stage at diagnosisNathan L Kobrinsky
Roger Maris Cancer Center, Fargo, North Dakota, USA
J Clin Oncol 21:907-13. 2003..Studies evaluating the relationship between smoking and cancer spread are limited...
Chain reaction or time bomb: a neuropsychiatric-developmental/neurodevelopmental formulation of tourettisms, pervasive developmental disorder, and schizophreniform symptomatology associated with PANDASJacob Kerbeshian
Department of Neuroscience, University of North Dakota School of Medicine and Health Sciences, Grand Forks, ND 58202, USA
World J Biol Psychiatry 8:201-7. 2007..Our main emphasis is to utilize our case study as an example of the application in case formulation of the neuropsychiatric developmental model and of the neurodevelopmental model on symptom ontogenesis and clinical outcome...
Review of published studies of kidney, liver, and gastrointestinal birth defects in fetal alcohol spectrum disordersRyan Hofer
North Dakota Fetal Alcohol Syndrome Center, Department of Pediatrics, University of North Dakota School of Medicine and Health Sciences, 501 North Columbia Road, Grand Forks, ND 58203 9037, USA
Birth Defects Res A Clin Mol Teratol 85:179-83. 2009..Review of published studies of birth defects of the renal, liver, and gastrointestinal organ systems in subjects with fetal alcohol spectrum disorders (FASD)...
Body mass index in fetal alcohol syndromeMarilyn G Klug
North Dakota Fetal Alcohol Syndrome Center, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, ND 58203, USA
Neurotoxicol Teratol 25:689-96. 2003..DISCUSSION: The requirement for growth impairment needs to be broad rather than narrow, if most subjects with a diagnosis of FAS and partial FAS/ARND are to be captured...
Genetic thrombophilia variants and risk for preeclampsia among American IndiansLyle G Best
Turtle Mountain Community College, Belcourt, North Dakota, USA
Hypertens Pregnancy 28:85-94. 2009..To determine the prevalence of thrombophilic genetic variants in an American Indian population and determine if they are associated with preeclampsia...
Fetal alcohol syndrome prevention: annual and cumulative cost savingsMarilyn G Klug
Department of Pediatrics, North Dakota Fetal Alcohol Syndrome Center, University of North Dakota School of Medicine and Health Sciences, 501 N. Columbia Road, Grand Forks, ND 58203, USA
Neurotoxicol Teratol 25:763-5. 2003..After 10 years of prevention, the annual savings in health care costs alone for one case of FAS would be US23,420 dollars...
A school-based screening program for fetal alcohol syndromeBetty A Poitra
Turtle Mountain Community Schools, and Turtle Mountain FAS Community Response Team, USA
Neurotoxicol Teratol 25:725-9. 2003..The procedure was well accepted in the community. This screening strategy was inexpensive to implement (less than US8.00 dollars per student), and can be easily included with the other screens completed at kindergarten entry...
Effects of maternal and paternal age on Caucasian and Native American preterm births and birth weightsErnest L Abel
Department of Obstetrics and Gynecology, C.S. Mott Center for Human Growth and Development, Wayne State University, Detroit, Michigan, USA
Am J Perinatol 19:49-54. 2002..The influence of teenage fathers on preterm and LBWs has not been previously reported, and the finding that paternal age has a greater influence among Native Americans is especially intriguing and deserving of further investigation...
Infant mortality reviews in the Aberdeen Area of the Indian Health Service: strategies and outcomesMary Lynn EagleStaff
Aberdeen Area of the Indian Health Service, Aberdeen, SD, USA
Public Health Rep 121:140-8. 2006..These include increasing data on substance use, mental health needs, and reviews of fetal deaths. The process of mortality review has been very helpful in public education in the AAIHS...
Cost of fetal alcohol spectrum disordersChuck Lupton
Fetal Alcohol Spectrum Disorders Center for Excellence, SAMHSA NIH DHHS, 1700 Research Boulevard, Suite 400, Rockville, MD 20850, USA
Am J Med Genet C Semin Med Genet 127:42-50. 2004..Each day, from 6-22 infants with FAS are born in the United States, and as many as 87-103 more are born with other impairments resulting from prenatal alcohol exposure. Updated and improved cost data on FAS should be a research priority...
