Research Topics
| Irina BurdSummaryAffiliation: University of Pennsylvania Country: USA Publications
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Detail Information
Publications
Maternal mortality from systemic illness: unraveling the contribution of the immune responseJuan M Gonzalez
Maternal and Child Health Research Program, Department of Obstetrics and Gynecology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
Am J Obstet Gynecol 200:430.e1-8. 2009..Alterations in the immune response could account for the increase MM. We sought to determine whether the immune response is functionally different during pregnant and nonpregnant (NP) states...
Inflammation-induced preterm birth alters neuronal morphology in the mouse fetal brainIrina Burd
Maternal and Child Health Research Program, Department of Obstetrics and Gynecology, Center for Research on Reproduction and Women s Health, University of Pennsylvania, Philadelphia, PA 19104 6142, USA
J Neurosci Res 88:1872-81. 2010..001, ANOVA between groups). These results suggest that inflammation-induced preterm birth and not the process of preterm birth may result in neuroinflammation and alter fetal neuronal morphology...
Magnesium sulfate reduces inflammation-associated brain injury in fetal miceIrina Burd
Maternal and Child Health Research Program, Department of Obstetrics and Gynecology, Center for Research on Reproduction and Women s Health, University of Pennsylvania, 1353 Biomedical Research Bldg II III, 421 Curie Blvd, Philadelphia, PA 19104 6142, USA
Am J Obstet Gynecol 202:292.e1-9. 2010..The purpose of this study was to investigate whether magnesium sulfate (MgSO(4)) prevents fetal brain injury in inflammation-associated preterm birth (PTB)...
TLR-4-dependent and -independent mechanisms of fetal brain injury in the setting of preterm birthKelsey Breen
Maternal and Child Health Research Program, Department of OBGYN, Center for Research on Reproduction and Women s Health, University of Pennsylvania Health System, Philadelphia, PA 19104, USA
Reprod Sci 19:839-50. 2012..However, injured neurons could induce injury in other neurons regardless of TLR-4 competency. Our results indicate that initiation of neuronal injury is a TLR-4-dependent event, while propagation is a TLR-4-independent event...
Beyond white matter damage: fetal neuronal injury in a mouse model of preterm birthIrina Burd
Department of Obstetrics and Gynecology, Center for Research on Reproduction and Women s Health, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6142, USA
Am J Obstet Gynecol 201:279.e1-8. 2009..The purpose of this study was to elucidate possible mechanisms of fetal neuronal injury in inflammation-induced preterm birth...
Intrauterine inflammation, insufficient to induce parturition, still evokes fetal and neonatal brain injuryMichal A Elovitz
Maternal and Child Health Research Program, Department of Obstetrics and Gynecology, Center for Research in Reproduction and Women s Health, University of Pennsylvania School of Medicine, 421 Curie Blvd, 1354 BRB 2 3, Philadelphia, PA 19104 6142, United States
Int J Dev Neurosci 29:663-71. 2011..Subclinical intrauterine inflammation can lead to fetal brain injury and is likely to be mechanistically associated with long term adverse outcomes for exposed offspring...
A mouse model of term chorioamnionitis: unraveling causes of adverse neurological outcomesIrina Burd
Maternal and Child Health Research Program, Department of Obstetrics and Gynecology, Center for Research on Reproduction and Women s Health, University of Pennsylvania, Philadelphia, PA 19104, USA
Reprod Sci 18:900-7. 2011..05). These studies may provide a critical mechanism for the observed long-term adverse neurobehavioral outcomes after exposure to chorioamnionitis at term...
Is sonographic assessment of fetal weight influenced by formula selection?Irina Burd
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of Pennsylvania, 2000 Courtyard, 3400 Spruce St, Philadelphia, PA 19104 6142 USA
J Ultrasound Med 28:1019-24. 2009..The aims of our study were to assess and compare the performance of different EFW formulas in predicting actual birth weight (BW) in an urban population...
Impact of the recent randomized trials on the use of progesterone to prevent preterm birth: a 2005 follow-up surveyAmen Ness
Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Jefferson Medical College of Thomas Jefferson University, Philadelphia, PA, USA
Am J Obstet Gynecol 195:1174-9. 2006..Among users, many are using it for indications not yet proven in clinical trials. Current nonusers have higher levels of concerns compared to nonusers in the first survey and their major concern is the need for more data...
