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Genomes and Genes | Brandon J BurbachSummaryAffiliation: University of Minnesota Country: USA Publications
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Publications
The pleckstrin homology domain in the SKAP55 adapter protein defines the ability of the adapter protein ADAP to regulate integrin function and NF-kappaB activationBrandon J Burbach
Department of Laboratory Medicine and Pathology, Center for Immunology, Masonic Cancer Center, University of Minnesota Medical School, Minneapolis, MN 55414, USA
J Immunol 186:6227-37. 2011....- Distinct regulation of integrin-dependent T cell conjugate formation and NF-kappa B activation by the adapter protein ADAPBrandon J Burbach
Department of Laboratory Medicine and Pathology, Masonic Cancer Center, University of Minnesota Medical School, Minneapolis, MN 55455, USA
J Immunol 181:4840-51. 2008.... - NF-kappaB activation in T cells requires discrete control of IkappaB kinase alpha/beta (IKKalpha/beta) phosphorylation and IKKgamma ubiquitination by the ADAP adapter proteinRupa Srivastava
Department of Laboratory Medicine and Pathology, Center for Immunology, Masonic Cancer Center, University of Minnesota Medical School, Minneapolis, Minnesota 55455, USA
J Biol Chem 285:11100-5. 2010..In contrast, only the CARMA1 binding site in ADAP is required for ubiquitination of IKKgamma. Thus, distinct sites within ADAP control two key activation responses that are required for NF-kappaB activation in T cells... 
Adhesion and degranulation-promoting adapter protein (ADAP) positively regulates T cell sensitivity to antigen and T cell survivalKristen L Mueller
Department of Laboratory Medicine and Pathology, Center for Immunology, Cancer Center, University of Minnesota Medical School, Minneapolis, MN 55455, USA
J Immunol 179:3559-69. 2007....- Regulation of NF-kappaB activation in T cells via association of the adapter proteins ADAP and CARMA1Ricardo B Medeiros
Department of Laboratory Medicine and Pathology, Center for Immunology, Cancer Center, University of Minnesota Medical School, Minneapolis, MN 55455, USA
Science 316:754-8. 2007..These findings provide new insights into ADAP function and the mechanism by which CARMA1 regulates NF-kappaB activation in T cells... - T-cell receptor signaling to integrinsBrandon J Burbach
Department of Laboratory Medicine and Pathology, Center for Immunology, University of Minnesota Medical School, Minneapolis, MN 55455, USA
Immunol Rev 218:65-81. 2007..These events coordinate changes in integrin conformation and clustering that result in enhanced integrin functional activity following TCR stimulation... - ADAP regulates cell cycle progression of T cells via control of cyclin E and Cdk2 expression through two distinct CARMA1-dependent signaling pathwaysRupa Srivastava
Department of Laboratory Medicine and Pathology, Center for Immunology, Masonic Cancer Center, University of Minnesota Medical School, Minneapolis, Minnesota, USA
Mol Cell Biol 32:1908-17. 2012..Thus, ADAP coordinates distinct CARMA1-dependent control of key cell cycle proteins in T cells... - β-Actin specifically controls cell growth, migration, and the G-actin poolTina M Bunnell
Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN 55455, USA
Mol Biol Cell 22:4047-58. 2011..These data support an essential role for β-actin in regulating cell migration and gene expression through control of the cellular G-actin pool... - ADAP is dispensable for NK cell development and functionLindsey V Fostel
Department of Internal Medicine, University of Minnesota Medical School, Center for Immunology, Cancer Center, University of Minnesota, Minneapolis, 55455, USA
Int Immunol 18:1305-14. 2006..These results indicate that, unlike events stimulated by TCR engagement, signaling events engaged by immunoreceptor tyrosine-based activation motif-associated and cytokine receptors on NK cells can occur independently of ADAP...