Brandon J Burbach

Summary

Affiliation: University of Minnesota
Country: USA

Publications

  1. pmc The pleckstrin homology domain in the SKAP55 adapter protein defines the ability of the adapter protein ADAP to regulate integrin function and NF-kappaB activation
    Brandon J Burbach
    Department of Laboratory Medicine and Pathology, Center for Immunology, Masonic Cancer Center, University of Minnesota Medical School, Minneapolis, MN 55414, USA
    J Immunol 186:6227-37. 2011
  2. pmc Distinct regulation of integrin-dependent T cell conjugate formation and NF-kappa B activation by the adapter protein ADAP
    Brandon J Burbach
    Department of Laboratory Medicine and Pathology, Masonic Cancer Center, University of Minnesota Medical School, Minneapolis, MN 55455, USA
    J Immunol 181:4840-51. 2008
  3. pmc NF-kappaB activation in T cells requires discrete control of IkappaB kinase alpha/beta (IKKalpha/beta) phosphorylation and IKKgamma ubiquitination by the ADAP adapter protein
    Rupa Srivastava
    Department of Laboratory Medicine and Pathology, Center for Immunology, Masonic Cancer Center, University of Minnesota Medical School, Minneapolis, Minnesota 55455, USA
    J Biol Chem 285:11100-5. 2010
  4. pmc Multistage T cell-dendritic cell interactions control optimal CD4 T cell activation through the ADAP-SKAP55-signaling module
    Jason S Mitchell
    Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, Minneapolis, MN 55455, USA
    J Immunol 191:2372-83. 2013
  5. ncbi request reprint Adhesion and degranulation-promoting adapter protein (ADAP) positively regulates T cell sensitivity to antigen and T cell survival
    Kristen L Mueller
    Department of Laboratory Medicine and Pathology, Center for Immunology, Cancer Center, University of Minnesota Medical School, Minneapolis, MN 55455, USA
    J Immunol 179:3559-69. 2007
  6. pmc ADAP regulates cell cycle progression of T cells via control of cyclin E and Cdk2 expression through two distinct CARMA1-dependent signaling pathways
    Rupa Srivastava
    Department of Laboratory Medicine and Pathology, Center for Immunology, Masonic Cancer Center, University of Minnesota Medical School, Minneapolis, Minnesota, USA
    Mol Cell Biol 32:1908-17. 2012
  7. ncbi request reprint T-cell receptor signaling to integrins
    Brandon J Burbach
    Department of Laboratory Medicine and Pathology, Center for Immunology, University of Minnesota Medical School, Minneapolis, MN 55455, USA
    Immunol Rev 218:65-81. 2007
  8. ncbi request reprint Regulation of NF-kappaB activation in T cells via association of the adapter proteins ADAP and CARMA1
    Ricardo B Medeiros
    Department of Laboratory Medicine and Pathology, Center for Immunology, Cancer Center, University of Minnesota Medical School, Minneapolis, MN 55455, USA
    Science 316:754-8. 2007
  9. pmc β-Actin specifically controls cell growth, migration, and the G-actin pool
    Tina M Bunnell
    Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN 55455, USA
    Mol Biol Cell 22:4047-58. 2011
  10. ncbi request reprint ADAP is dispensable for NK cell development and function
    Lindsey V Fostel
    Department of Internal Medicine, University of Minnesota Medical School, Center for Immunology, Cancer Center, University of Minnesota, Minneapolis, 55455, USA
    Int Immunol 18:1305-14. 2006

Collaborators

  • Yoji Shimizu
  • Brian T Fife
  • Rupa Srivastava
  • Jason S Mitchell
  • Kristen L Mueller
  • Erik J Peterson
  • Tina M Bunnell
  • Ricardo B Medeiros
  • Lindsey V Fostel
  • Antonio J Pagán
  • James M Ervasti
  • James J Moon
  • Sarah Highfill
  • Molly S Thomas
  • Joanna Dluzniewska

Detail Information

Publications10

  1. pmc The pleckstrin homology domain in the SKAP55 adapter protein defines the ability of the adapter protein ADAP to regulate integrin function and NF-kappaB activation
    Brandon J Burbach
    Department of Laboratory Medicine and Pathology, Center for Immunology, Masonic Cancer Center, University of Minnesota Medical School, Minneapolis, MN 55414, USA
    J Immunol 186:6227-37. 2011
    ....
  2. pmc Distinct regulation of integrin-dependent T cell conjugate formation and NF-kappa B activation by the adapter protein ADAP
    Brandon J Burbach
    Department of Laboratory Medicine and Pathology, Masonic Cancer Center, University of Minnesota Medical School, Minneapolis, MN 55455, USA
    J Immunol 181:4840-51. 2008
    ....
  3. pmc NF-kappaB activation in T cells requires discrete control of IkappaB kinase alpha/beta (IKKalpha/beta) phosphorylation and IKKgamma ubiquitination by the ADAP adapter protein
    Rupa Srivastava
    Department of Laboratory Medicine and Pathology, Center for Immunology, Masonic Cancer Center, University of Minnesota Medical School, Minneapolis, Minnesota 55455, USA
    J Biol Chem 285:11100-5. 2010
    ..In contrast, only the CARMA1 binding site in ADAP is required for ubiquitination of IKKgamma. Thus, distinct sites within ADAP control two key activation responses that are required for NF-kappaB activation in T cells...
  4. pmc Multistage T cell-dendritic cell interactions control optimal CD4 T cell activation through the ADAP-SKAP55-signaling module
    Jason S Mitchell
    Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, Minneapolis, MN 55455, USA
    J Immunol 191:2372-83. 2013
    ..Thus, integrin activation by the ADAP-SKAP55-signaling module controls the stability and duration of T cell-dendritic cell contacts during the progressive phases necessary for optimal T cell activation. ..
  5. ncbi request reprint Adhesion and degranulation-promoting adapter protein (ADAP) positively regulates T cell sensitivity to antigen and T cell survival
    Kristen L Mueller
    Department of Laboratory Medicine and Pathology, Center for Immunology, Cancer Center, University of Minnesota Medical School, Minneapolis, MN 55455, USA
    J Immunol 179:3559-69. 2007
    ....
  6. pmc ADAP regulates cell cycle progression of T cells via control of cyclin E and Cdk2 expression through two distinct CARMA1-dependent signaling pathways
    Rupa Srivastava
    Department of Laboratory Medicine and Pathology, Center for Immunology, Masonic Cancer Center, University of Minnesota Medical School, Minneapolis, Minnesota, USA
    Mol Cell Biol 32:1908-17. 2012
    ..Thus, ADAP coordinates distinct CARMA1-dependent control of key cell cycle proteins in T cells...
  7. ncbi request reprint T-cell receptor signaling to integrins
    Brandon J Burbach
    Department of Laboratory Medicine and Pathology, Center for Immunology, University of Minnesota Medical School, Minneapolis, MN 55455, USA
    Immunol Rev 218:65-81. 2007
    ..These events coordinate changes in integrin conformation and clustering that result in enhanced integrin functional activity following TCR stimulation...
  8. ncbi request reprint Regulation of NF-kappaB activation in T cells via association of the adapter proteins ADAP and CARMA1
    Ricardo B Medeiros
    Department of Laboratory Medicine and Pathology, Center for Immunology, Cancer Center, University of Minnesota Medical School, Minneapolis, MN 55455, USA
    Science 316:754-8. 2007
    ..These findings provide new insights into ADAP function and the mechanism by which CARMA1 regulates NF-kappaB activation in T cells...
  9. pmc β-Actin specifically controls cell growth, migration, and the G-actin pool
    Tina M Bunnell
    Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN 55455, USA
    Mol Biol Cell 22:4047-58. 2011
    ..These data support an essential role for β-actin in regulating cell migration and gene expression through control of the cellular G-actin pool...
  10. ncbi request reprint ADAP is dispensable for NK cell development and function
    Lindsey V Fostel
    Department of Internal Medicine, University of Minnesota Medical School, Center for Immunology, Cancer Center, University of Minnesota, Minneapolis, 55455, USA
    Int Immunol 18:1305-14. 2006
    ..These results indicate that, unlike events stimulated by TCR engagement, signaling events engaged by immunoreceptor tyrosine-based activation motif-associated and cytokine receptors on NK cells can occur independently of ADAP...