Research Topics
Species | Patricia BufflerSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
Household vacuum cleaners vs. the high-volume surface sampler for collection of carpet dust samples in epidemiologic studies of childrenJoanne S Colt
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, 6120 Executive Blvd MSC 7240, Bethesda, MD, 20892 7240, USA
Environ Health 7:6. 2008..Here, we compare levels of pesticides and other compounds in dust from household vacuums to that collected using the HVS3...- FLT3 mutation incidence and timing of origin in a population case series of pediatric leukemiaPatrick Chang
Department of Epidemiology and Biostatistics, UCSF, Helen Diller Cancer Research Building, San Francisco, CA 94158, USA
BMC Cancer 10:513. 2010..The causes and timing of the mutations are not currently known. We evaluated the prevalence and timing of origin of FLT3 mutations in a population series of childhood leukemia patients from Northern California... 
Primary brain tumor mortality at a petroleum exploration and extraction research facilityPatricia A Buffler
University of California, Berkeley, CA 94720 7360, USA
J Occup Environ Med 46:257-70. 2004..Although conclusions are limited by the small study population and lack of specific exposure data, these findings were not consistent with an occupational explanation for the observed brain tumor cluster...- A nested case-control study of brain tumors among employees at a petroleum exploration and extraction research facilityPatricia A Buffler
University of California, Berkeley, School of Public Health, Berkeley, CA 94720 7360, USA
J Occup Environ Med 49:791-802. 2007..0, 95% CI = 0.4-10.7). While some ORs above 1.5 were noted, no work-related chemical and physical exposures were significantly associated with the occurrence of brain tumors among employees at this facility... - Environmental and genetic risk factors for childhood leukemia: appraising the evidencePatricia A Buffler
School of Public Health, University of California, Berkeley, CA 94720 7360, USA
Cancer Invest 23:60-75. 2005..We hope to provide the reader with an understanding of the challenge and promise that characterizes the current and future directions in childhood leukemia research... - Determinants of polycyclic aromatic hydrocarbon levels in house dustTodd Whitehead
School of Public Health, University of California, Berkeley, California 94720, USA
J Expo Sci Environ Epidemiol 21:123-32. 2011..As self-reported data and outdoor PAH sources were only marginally predictive of observed PAH levels, we recommend that PAH concentrations be measured directly in dust samples for use in epidemiological studies... 
Estimating exposures to indoor contaminants using residential dustTodd Whitehead
School of Public Health, University of California, Berkeley, California 94720, USA
J Expo Sci Environ Epidemiol 21:549-64. 2011..We conclude our review with a discussion of the current gaps in knowledge of worldwide dust levels and suggestions for how residential-dust measurements could be used to describe human exposures to chemicals in developing countries...- Residential traffic density and childhood leukemia riskJulie Von Behren
Northern California Cancer Center, Berkeley, CA 94704, USA
Cancer Epidemiol Biomarkers Prev 17:2298-301. 2008..Exposures to carcinogenic compounds from vehicle exhaust may increase childhood leukemia risk, and the timing of this exposure may be important... - Is house-dust nicotine a good surrogate for household smoking?Todd Whitehead
School of Public Health, University of California, Berkeley, CA 94720, USA
Am J Epidemiol 169:1113-23. 2009.... - Exposure to electrical contact currents and the risk of childhood leukemiaMonique Does
School of Public Health, University of California, Berkeley, Berkeley, California, USA
Radiat Res 175:390-6. 2011.... - Maternal dietary risk factors in childhood acute lymphoblastic leukemia (United States)Christopher D Jensen
School of Public Health, 419 Warren Hall, University of California, Berkeley, CA 94720 7360, USA
Cancer Causes Control 15:559-70. 2004..Recent research has established that the disease can originate in utero, and thus maternal diet may be an important risk factor for ALL... - Parental smoking and the risk of childhood leukemiaJeffrey S Chang
School of Public Health, University of California, Berkeley, CA 94720 7380, USA
Am J Epidemiol 163:1091-100. 2006..004). These results strongly suggest that exposure to paternal preconception smoking alone or in combination with postnatal passive smoking may be important in the risk of childhood leukemia... - Cytogenetics of Hispanic and White children with acute lymphoblastic leukemia in CaliforniaMelinda C Aldrich
University of California Berkeley, 2150 Shattuck Avenue, Suite 500, Berkeley, CA 94720 7380, USA
Cancer Epidemiol Biomarkers Prev 15:578-81. 2006..The mechanistic basis for this 2-fold variation in frequency of TEL-AML1 may be due to ethnic-specific risk factors or genetics and should be explored further... - Factors associated with residential mobility in children with leukemia: implications for assigning exposuresKevin Y Urayama
School of Public Health, University of California, Berkeley, CA 94704, USA
Ann Epidemiol 19:834-40. 2009..The authors evaluated residential mobility patterns for a population-based series of childhood leukemia cases enrolled in the Northern California Childhood Leukemia Study... - Genetic susceptibility to childhood leukaemiaAnand P Chokkalingam
School of Public Health, University of California, Berkeley, CA 94704 7380 USA
Radiat Prot Dosimetry 132:119-29. 2008.... - Exposure to infections through day-care attendance and risk of childhood leukaemiaKevin Y Urayama
School of Public Health, University of California, Berkeley, 2150 Shattuck Avenue, Suite 500, Berkeley, CA 94704, USA
Radiat Prot Dosimetry 132:259-66. 2008..A meta-analysis is currently underway, which will provide a quantitative evaluation of the overall consistency and strength of the association between day-care attendance or social contact and risk of childhood ALL... - Residential exposures to pesticides and childhood leukaemiaCatherine Metayer
School of Public Health, University of California, 2150 Shattuck Avenue, Suite 500, Berkeley, CA 94720 7080, USA
Radiat Prot Dosimetry 132:212-9. 2008..A better quantification of children's exposures to pesticides at home is critical to the evaluation of childhood leukaemia risk, especially for future gene-environment interaction studies... - NQO1 polymorphisms and de novo childhood leukemia: a HuGE review and meta-analysisNeela Guha
Division of Epidemiology, School of Public Health, University of California, Berkeley, California 94704, USA
Am J Epidemiol 168:1221-32. 2008..Therefore, further research is warranted on the role of NQO1 polymorphisms in the etiology of childhood leukemia, especially among MLL-positive leukemias... - Household exposure to paint and petroleum solvents, chromosomal translocations, and the risk of childhood leukemiaGhislaine Scelo
School of Public Health, University of California Berkeley, Berkeley, California 94704 7380, USA
Environ Health Perspect 117:133-9. 2009..Few studies have examined the association between home use of solvents and paint and the risk of childhood leukemia... - Residential proximity to agricultural pesticide applications and childhood acute lymphoblastic leukemiaRudolph P Rull
Northern California Cancer Center, 2001 Center Street, Suite 700, Berkeley, CA 94704, USA
Environ Res 109:891-9. 2009..A similar pattern was also observed for several toxicological groups of pesticides. These findings suggest future directions for the identification of specific pesticides that may play a role in the etiology of childhood leukemia... 
Integrating research, surveillance, and practice in environmental public health trackingAmy D Kyle
School of Public Health, University of California, Berkeley, California, USA
Environ Health Perspect 114:980-4. 2006..The fourth is to promote disease prevention by systematically identifying and addressing population-level environmental determinants of health and disease...- Use of an index to reflect the aggregate burden of long-term exposure to criteria air pollutants in the United StatesAmy D Kyle
School of Public Health, University of California Berkeley, Berkeley, California 94720, USA
Environ Health Perspect 110:95-102. 2002.... - Critical windows of exposure to household pesticides and risk of childhood leukemiaXiaomei Ma
School of Public Health, University of California, Berkeley, California 24720, USA
Environ Health Perspect 110:955-60. 2002..The findings suggest that exposure to household pesticides is associated with an elevated risk of childhood leukemia and further indicate the importance of the timing and location of exposure... - Food consumption by children and the risk of childhood acute leukemiaMarilyn L Kwan
Division of Public Health Biology and Epidemiology, School of Public Health, University of California, Berkeley, CA 94720 7380, USA
Am J Epidemiol 160:1098-107. 2004..These results suggest that fruits or fruit juices that contain vitamin C and/or potassium may reduce the risk of childhood leukemia, especially if they are consumed on a regular basis during the first 2 years of life... - Breastfeeding and the risk of childhood leukemia: a meta-analysisMarilyn L Kwan
Division of Public Health Biology and Epidemiology, School of Public Health, University of California, Berkeley, CA 94720, USA
Public Health Rep 119:521-35. 2004.... - Spatial analysis of childhood leukemia in a case/control studySteve Selvin
School of Public Health, University of California, Berkeley, Berkeley, CA 94720, USA
Int J Hyg Environ Health 207:555-62. 2004..01) arising from a frequency analysis of concordant case pairs. Although these p-values accurately reflect the probability of the observed spatial pattern occurring by chance alone, these results are based on only four cases of leukemia... - Molecular biomarkers for the study of childhood leukemiaMartyn T Smith
Division of Environmental Health Sciences, School of Public Health, University of California, 140 Warren Hall, Berkeley, CA 94720 7360, USA
Toxicol Appl Pharmacol 206:237-45. 2005..Several proteins have been identified that may serve as useful biomarkers for rapidly identifying different forms of childhood leukemia... - Diagnostic X-rays and risk of childhood leukaemiaKaren Bartley
School of Public Health, University of California, Berkeley, CA, USA
Int J Epidemiol 39:1628-37. 2010..The association between diagnostic X-ray exposures early in life and increased risk of childhood leukaemia remains unclear... - Development and evaluation of parental occupational exposure questionnaires for a childhood leukemia studyKyndaron Reinier
School of Public Health, Division of Public Health Biology and Epidemiology, University of California, Berkeley, Berkeley, California, United States
Scand J Work Environ Health 30:450-8. 2004.... - Ambient UVB and melanoma risk in the United States: a case-control analysisC Suzanne Lea
Department of Epidemiology and Public Health Biology, University of California, Berkeley, Berkeley, CA USA
Ann Epidemiol 17:447-53. 2007..This study assessed cumulative UVB using a ground-based measurement instrument to estimate the association between UVB and melanoma... - A review: dietary and endogenously formed N-nitroso compounds and risk of childhood brain tumorsMarion Dietrich
School of Public Health, University of California Berkeley, Berkeley, CA 94720 7360, USA
Cancer Causes Control 16:619-35. 2005..This approach may be helpful in determining the essential information that must be collected in future epidemiological studies on CBT... - CYP1A1/2 haplotypes and lung cancer and assessment of confounding by population stratificationMelinda C Aldrich
Department of Medicine and Division of Neuroepidemiology, University of California, San Francisco, California, USA
Cancer Res 69:2340-8. 2009..These results suggest that a variant occurring within the CYP1A2 region may be conferring an increased risk of lung cancer in Latinos... - Surveillance and survival in Barrett's adenocarcinomas: a population-based studyDouglas A Corley
The School of Public Health, University of California, Berkeley, California 94115, USA
Gastroenterology 122:633-40. 2002..We evaluated the association between endoscopic surveillance of BE and survival among esophageal/gastric cardia adenocarcinoma patients... - A meta-analysis of the association between day-care attendance and childhood acute lymphoblastic leukaemiaKevin Y Urayama
School of Public Health, University of California, Berkeley, CA 94720, USA
Int J Epidemiol 39:718-32. 2010..A meta-analysis was conducted to examine the relationship between day-care attendance and risk of childhood ALL, specifically to address whether early-life exposure to infection is protective against ALL... - Comparison of statistical methods for estimating genetic admixture in a lung cancer study of African Americans and LatinosMelinda C Aldrich
University of California, San Francisco, Box 2911 Rock Hall, Mission Bay 582, 1550 4th Street, San Francisco, CA 94143 2911, USA
Am J Epidemiol 168:1035-46. 2008..Genetic admixture proportions provide a quantitative measure of ancestry differences among Latinos that can be used in analyses of genetic risk factors... - Issues of diagnostic review in brain tumor studies: from the Brain Tumor Epidemiology ConsortiumFaith G Davis
Division of Epidemiology Biostatistics, School of Public Health, University of Illinois at Chicago, Chicago, IL 60612, USA
Cancer Epidemiol Biomarkers Prev 17:484-9. 2008..It is essential that epidemiologists and neuropathologists collaborate to develop appropriate study designs and protocols for specific hypothesis and populations... - Site-specific translocation and evidence of postnatal origin of the t(1;19) E2A-PBX1 fusion in childhood acute lymphoblastic leukemiaJoseph L Wiemels
Department of Epidemiology and Biostatistics, University of California, San Francisco 94143, USA
Proc Natl Acad Sci U S A 99:15101-6. 2002.... - Prenatal origin of TEL-AML1-positive acute lymphoblastic leukemia in children born in CaliforniaCliona M McHale
School of Public Health, University of California, Berkeley 94720-7360, USA
Genes Chromosomes Cancer 37:36-43. 2003..Secondary changes were also similar to those described previously, with deletion of the second TEL allele being the most common. Other secondary changes included duplication of the fusion gene, trisomy 21, and monosomy X... - Thyroid function and perchlorate in drinking water: an evaluation among California newborns, 1998Patricia A Buffler
University of California, Berkeley, California, and Nemours Children's Clinic, Orlando, FL, USA
Environ Health Perspect 114:798-804. 2006.... - Ethnic difference in daycare attendance, early infections, and risk of childhood acute lymphoblastic leukemiaXiaomei Ma
Department of Epidemiology and Public Health, Yale University School of Medicine, 60 College Street, New Haven, CT 06520 8034, USA
Cancer Epidemiol Biomarkers Prev 14:1928-34. 2005..These results offer indirect yet strong support for the infectious disease hypothesis in the etiology of ALL in non-Hispanic White children and highlight an important ethnic difference... - Maternal pregnancy loss, birth characteristics, and childhood leukemia (United States)Xiaomei Ma
Department of Epidemiology and Public Health, Yale University School of Medicine, 60 College St, New Haven, CT 06520 8034, USA
Cancer Causes Control 16:1075-83. 2005..The authors evaluated the relation between maternal pregnancy loss, birth characteristics, and childhood leukemia in the Northern California Childhood Leukemia Study... - In utero origin of t(8;21) AML1-ETO translocations in childhood acute myeloid leukemiaJoseph L Wiemels
Laboratory for Molecular Epidemiology, Department of Epidemiology and Biostatistics, University of California San Francisco 94143 0560, USA
Blood 99:3801-5. 2002.... - Secondhand smoke exposure in adulthood and risk of lung cancer among never smokers: a pooled analysis of two large studiesPaul Brennan
International Agency for Research on Cancer, Lyon, France
Int J Cancer 109:125-31. 2004..Clear dose-response relationships consistent with a causal association were observed between exposure to secondhand smoke from spousal, workplace and social sources and the development of lung cancer among never smokers... - Hypermethylation of the 5' CpG island of the FHIT gene is associated with hyperdiploid and translocation-negative subtypes of pediatric leukemiaShichun Zheng
Laboratory for Molecular Epidemiology, Department of Epidemiology and Biostatistics, University of California at San Francisco, San Francisco, CA 94143 0560, USA
Cancer Res 64:2000-6. 2004..These results suggest that hypermethylation of the promoter region CpG island of the FHIT gene is a common event and may play an important role in the etiology and pathophysiology of specific cytogenetic subtypes of childhood ALL... - Control selection strategies in case-control studies of childhood diseasesXiaomei Ma
Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT 06520 8034, USA
Am J Epidemiol 159:915-21. 2004..0% for 560 enrolled birth certificate controls), using birth records to recruit controls appears to provide a representative sample of children and an opportunity to assess the representativeness of controls... - Maternal illness and drug/medication use during the period surrounding pregnancy and risk of childhood leukemia among offspringMarilyn L Kwan
Division of Research, Kaiser Permanente, Oakland, CA 94612, USA
Am J Epidemiol 165:27-35. 2007..Furthermore, maternal iron supplement use may be protective against childhood leukemia... - Brain tumor epidemiology: consensus from the Brain Tumor Epidemiology ConsortiumMelissa L Bondy
Department of Epidemiology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
Cancer 113:1953-68. 2008..In this report, BTEC epidemiologists reviewed the group's consensus on the current state of scientific findings, and they present a consensus on research priorities to identify which important areas the science should move to address... - Abdominal obesity and body mass index as risk factors for Barrett's esophagusDouglas A Corley
Division of Research, Kaiser Permanente, Oakland, California 94612, USA
Gastroenterology 133:34-41; quiz 311. 2007..Barrett's esophagus is a strong risk factor for esophageal adenocarcinoma, but little is known about its associations with body mass index (BMI) or abdominal obesity... - Barrett's esophagus and medications that relax the lower esophageal sphincterDouglas A Corley
Northern California Kaiser Permanente Division of Research, Oakland 94612, USA
Am J Gastroenterol 101:937-44. 2006..This association was only observed with asthma medications; the analyses suggested the possibility of confounding by indication, whereby reflux may cause both asthma and Barrett's esophagus... - The emergence of networks in human genome epidemiology: challenges and opportunitiesDaniela Seminara
Epidemiology and Genetics Research Branch, Division of Cancer Control and Population Sciences, National Cancer Institute, NIH, EPN Bldg, Rm. 5142, MSC 7393, 6130 Executive Blvd, Bethesda, MD 20892, USA
Epidemiology 18:1-8. 2007 - Monoclonal B-cell lymphocytosis as a biomarker in environmental health studiesRobert F Vogt
Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA, USA
Br J Haematol 139:690-700. 2007..This review summarizes the findings from those investigations and discusses the issues related to using MBL as a biomarker in environmental health research and population-based studies... - Family history of cancer among children with brain tumors: a critical reviewJoanna V Dearlove
Stanford Cancer Center, Stanford University School of Medicine, Palo Alto, CA 94305 5826, USA
J Pediatr Hematol Oncol 30:8-14. 2008..There is limited evidence that a family history of cancer is more common among families of childhood brain tumor patients... - Primary congenital hypothyroidism, newborn thyroid function, and environmental perchlorate exposure among residents of a Southern California communityMichael A Kelsh
Exponent, Inc, 149 Commonwealth Drive, Menlo Park, CA 94025, USA
J Occup Environ Med 45:1116-27. 2003..Age of the newborn at time of screening was the most important predictor of the TSH level. These findings suggest that residence in a community with potential perchlorate exposure has not impacted PCH rates or newborn thyroid function... - Socioeconomic status and childhood acute lymphocytic leukemia incidence in São Paulo, BrazilKarina Braga Ribeiro
Department of Social Medicine, Faculdade de Ciencias Medicas da Santa Casa de Sao Paulo, Sao Paulo, Brazil
Int J Cancer 123:1907-12. 2008..95, p < 0.001). Population-based attributes for SES and household size may be useful surrogate markers of early exposure to childhood infections, which has been found to decrease the risk of ALL... - Prenatal origin of childhood acute myeloid leukemias harboring chromosomal rearrangements t(15;17) and inv(16)Cliona M McHale
Blood 101:4640-1. 2003 - A road map for efficient and reliable human genome epidemiologyJohn P A Ioannidis
Clinical and Molecular Epidemiology Unit, Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, and Biomedical Research Institute, Foundation for Research and Technology Hellas, Ioannina 45110, Greece
Nat Genet 38:3-5. 2006..Systematic reviews will be expanded to include more meta-analyses of individual-level data and prospective meta-analyses. Field synopses will offer regularly updated overviews... - Vaccination history and risk of childhood leukaemiaXiaomei Ma
Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT 06520 8034, USA
Int J Epidemiol 34:1100-9. 2005..Previous studies on vaccination and childhood leukaemia generated inconsistent results...
Research Grants
- Childhood Leukemia and Home Environmental ExposuresPatricia A Buffler; Fiscal Year: 2010..This study will identify time trends in exposure levels that might have a significant impact on exposure levels during gestation and early childhood. ..
- Environmental and Molecular Epidemiology of Childhood LeukemiaPatricia Buffler; Fiscal Year: 2009..The culturally diverse population of the NCCLS ensures that environmental and genetic exposures unique to Hispanics will be examined. ..
- CHILDHOOD LEUKEMIA AND ENVIRONMENTAL EXPOSURESPatricia Buffler; Fiscal Year: 2009..abstract_text> ..
- Childhood Leukemia and Home Environmental ExposuresPatricia Buffler; Fiscal Year: 2009..This study will identify time trends in exposure levels that might have a significant impact on exposure levels during gestation and early childhood. ..
- CHILDHOOD LEUKEMIA AND ENVIRONMENTAL EXPOSURESPatricia Buffler; Fiscal Year: 2003..The proposed study, which will attempt to link specific chemical components with genetic changes found in childhood leukemia, will help to reduce the percentage of leukemias for which there is no known cause. ..
- Environmental and Molecular Epidemiology of Childhood LeukemiaPatricia A Buffler; Fiscal Year: 2010..The culturally diverse population of the NCCLS ensures that environmental and genetic exposures unique to Hispanics will be examined. ..