Michael J Buck

Summary

Affiliation: University of North Carolina
Country: USA

Publications

  1. pmc ChIPOTle: a user-friendly tool for the analysis of ChIP-chip data
    Michael J Buck
    Department of Biology, Carolina Center for Genome Sciences, CB 3280, University of North Carolina, Chapel Hill, NC 27599 3280, USA
    Genome Biol 6:R97. 2005
  2. ncbi request reprint Networks of coevolving sites in structural and functional domains of serpin proteins
    Michael J Buck
    Department of Genetics and The Center for Computational Biology, North Carolina State University, USA
    Mol Biol Evol 22:1627-34. 2005
  3. pmc A chromatin-mediated mechanism for specification of conditional transcription factor targets
    Michael J Buck
    Department of Biology and the Carolina Center for Genome Sciences, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA
    Nat Genet 38:1446-51. 2006
  4. pmc The stress response factors Yap6, Cin5, Phd1, and Skn7 direct targeting of the conserved co-repressor Tup1-Ssn6 in S. cerevisiae
    Sean E Hanlon
    Department of Biology, Carolina Center for Genome Sciences and Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America
    PLoS ONE 6:e19060. 2011
  5. pmc The RNA polymerase II kinase Ctk1 regulates positioning of a 5' histone methylation boundary along genes
    Tiaojiang Xiao
    Department of Biochemistry and Biophysics, University of North Carolina School of Medicine, 405 Mary Ellen Jones, Chapel Hill, NC 27599 7260, USA
    Mol Cell Biol 27:721-31. 2007
  6. pmc Improved ChIP-chip analysis by a mixture model approach
    Wei Sun
    Department of Biostatistics, Carolina Center for Genome Sciences, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
    BMC Bioinformatics 10:173. 2009
  7. pmc Global analysis of the relationship between the binding of the Bas1p transcription factor and meiosis-specific double-strand DNA breaks in Saccharomyces cerevisiae
    Piotr A Mieczkowski
    Department of Biology and Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 3280, USA
    Mol Cell Biol 26:1014-27. 2006
  8. ncbi request reprint ChIP-chip: considerations for the design, analysis, and application of genome-wide chromatin immunoprecipitation experiments
    Michael J Buck
    Department of Biology and Carolina Center for Genome Sciences, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 3280, USA
    Genomics 83:349-60. 2004
  9. ncbi request reprint Phylogenetic analysis of plant basic helix-loop-helix proteins
    Michael J Buck
    Department of Genetics and The Center for Computational Biology, North Carolina State University, Campus Box 7614, Raleigh, NC 27695 7614, USA
    J Mol Evol 56:742-50. 2003
  10. pmc Loss of a histone deacetylase dramatically alters the genomic distribution of Spo11p-catalyzed DNA breaks in Saccharomyces cerevisiae
    Piotr A Mieczkowski
    Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA
    Proc Natl Acad Sci U S A 104:3955-60. 2007

Collaborators

Detail Information

Publications10

  1. pmc ChIPOTle: a user-friendly tool for the analysis of ChIP-chip data
    Michael J Buck
    Department of Biology, Carolina Center for Genome Sciences, CB 3280, University of North Carolina, Chapel Hill, NC 27599 3280, USA
    Genome Biol 6:R97. 2005
    ..Implemented as a Microsoft Excel macro written in Visual Basic, ChIPOTle uses a sliding window approach that yields improvements in the identification of bona fide sites of protein-DNA interaction...
  2. ncbi request reprint Networks of coevolving sites in structural and functional domains of serpin proteins
    Michael J Buck
    Department of Genetics and The Center for Computational Biology, North Carolina State University, USA
    Mol Biol Evol 22:1627-34. 2005
    ..This research provides a better understanding on how protein structure evolves; in particular, it elucidates the selective forces creating coevolution among protein sites...
  3. pmc A chromatin-mediated mechanism for specification of conditional transcription factor targets
    Michael J Buck
    Department of Biology and the Carolina Center for Genome Sciences, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA
    Nat Genet 38:1446-51. 2006
    ....
  4. pmc The stress response factors Yap6, Cin5, Phd1, and Skn7 direct targeting of the conserved co-repressor Tup1-Ssn6 in S. cerevisiae
    Sean E Hanlon
    Department of Biology, Carolina Center for Genome Sciences and Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America
    PLoS ONE 6:e19060. 2011
    ....
  5. pmc The RNA polymerase II kinase Ctk1 regulates positioning of a 5' histone methylation boundary along genes
    Tiaojiang Xiao
    Department of Biochemistry and Biophysics, University of North Carolina School of Medicine, 405 Mary Ellen Jones, Chapel Hill, NC 27599 7260, USA
    Mol Cell Biol 27:721-31. 2007
    ....
  6. pmc Improved ChIP-chip analysis by a mixture model approach
    Wei Sun
    Department of Biostatistics, Carolina Center for Genome Sciences, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
    BMC Bioinformatics 10:173. 2009
    ..Most existing methods were designed for the identification of relatively sparse peaks, in the presence of replicates...
  7. pmc Global analysis of the relationship between the binding of the Bas1p transcription factor and meiosis-specific double-strand DNA breaks in Saccharomyces cerevisiae
    Piotr A Mieczkowski
    Department of Biology and Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 3280, USA
    Mol Cell Biol 26:1014-27. 2006
    ..These results argue that both local and regional factors affect the level of meiotic recombination...
  8. ncbi request reprint ChIP-chip: considerations for the design, analysis, and application of genome-wide chromatin immunoprecipitation experiments
    Michael J Buck
    Department of Biology and Carolina Center for Genome Sciences, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 3280, USA
    Genomics 83:349-60. 2004
    ....
  9. ncbi request reprint Phylogenetic analysis of plant basic helix-loop-helix proteins
    Michael J Buck
    Department of Genetics and The Center for Computational Biology, North Carolina State University, Campus Box 7614, Raleigh, NC 27695 7614, USA
    J Mol Evol 56:742-50. 2003
    ..We suggest that plant bHLH proteins are under weaker selective constraints than their animal counterparts and that lineage specific expansions and subfunctionalization have fashioned regulatory proteins for plant specific functions...
  10. pmc Loss of a histone deacetylase dramatically alters the genomic distribution of Spo11p-catalyzed DNA breaks in Saccharomyces cerevisiae
    Piotr A Mieczkowski
    Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA
    Proc Natl Acad Sci U S A 104:3955-60. 2007
    ..Some of the genes with altered frequencies of DSBs (including the ribosomal RNA gene cluster) are known targets of Sir2p deacetylation in the wild-type strain...