Research Topics
Genomes and Genes | David M BryantSummaryAffiliation: University of California Country: USA Publications
| Collaborators
|
Detail Information
Publications
From cells to organs: building polarized tissueDavid M Bryant
Department of Anatomy, University of California San Francisco, California 94143 2140, USA
Nat Rev Mol Cell Biol 9:887-901. 2008....
Reduced immunoglobulin A transcytosis associated with immunoglobulin A nephropathy and nasopharyngeal carcinomaTao Su
Department of Anatomy, University of California, San Francisco, California 94158, USA
J Biol Chem 286:44921-5. 2011..We propose that the defects in pIgR trafficking caused by the A580V mutation may underlie the pathogenesis of both diseases...
Molecular regulation of lumen morphogenesisAnirban Datta
Department of Anatomy, University of California San Francisco, CA 94143 2140, USA
Curr Biol 21:R126-36. 2011..We here discuss progress in understanding common design principles underpinning de novo lumen formation and expansion...
A molecular network for de novo generation of the apical surface and lumenDavid M Bryant
Department of Anatomy, University of California, San Francisco, CA 94143 2140, USA
Nat Cell Biol 12:1035-45. 2010..This Rab11a-directed network directs Cdc42-dependent apical exocytosis during lumen formation, revealing an interaction between the machineries of vesicular transport and polarization...
A kinase cascade leading to Rab11-FIP5 controls transcytosis of the polymeric immunoglobulin receptorTao Su
Department of Anatomy, University of California, San Francisco, CA 94158 2517, USA
Nat Cell Biol 12:1143-53. 2010..Finally, we demonstrate that Rab11-FIP5 phosphorylation by ERK controls Rab11a endosome distribution and pIgA-pIgR transcytosis. Our results reveal a novel Yes-EGFR-ERK-FIP5 signalling network for regulation of pIgA-pIgR transcytosis...
Involvement of RhoA, ROCK I and myosin II in inverted orientation of epithelial polarityWei Yu
Department of Anatomy, Neurology, University of California, San Francisco, California 94143, USA
EMBO Rep 9:923-9. 2008..These results might be relevant to the hyperactivation of RhoA and disruption of normal polarity frequently observed in human epithelial cancers...
