Research Topics
Species | Kristen L BrunsonSummaryAffiliation: University of California Country: USA Publications
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Publications
Stress and the developing hippocampus: a double-edged sword?Kristen L Brunson
Department of Anatomy and Neurobiology, University of CA at Irvine, Irvine, CA 92697, USA
Mol Neurobiol 27:121-36. 2003..We highlight the physiological and pathological roles of this peptide in the developing hippocampus, and their relevance to the long-term effects of early-life experience on cognitive function during adulthood...
Enduring, handling-evoked enhancement of hippocampal memory function and glucocorticoid receptor expression involves activation of the corticotropin-releasing factor type 1 receptorKristina A Fenoglio
Department of Anatomy Neurobiology, Med Sci I, ZOT 4475, University of California, Irvine, California 92697 4475, USA
Endocrinology 146:4090-6. 2005..Thus, the extent of CRF1 activation, probably involving changes in hypothalamic CRF levels and release, contributes to the changes in hippocampal GR expression and learning and memory functions...
Region-specific onset of handling-induced changes in corticotropin-releasing factor and glucocorticoid receptor expressionKristina A Fenoglio
19182 Jamboree Boulevard, University of California, Irvine, Med Sci I Room B160, Irvine, California 92697 4475, USA
Endocrinology 145:2702-6. 2004....
Hippocampal neurogenesis is not enhanced by lifelong reduction of glucocorticoid levelsKristen L Brunson
Departments of Anatomy/Neurobiology and Pediatrics, University of California at Irvine, Irvine, CA 92697-4475, USA
Hippocampus 15:491-501. 2005..Specifically, chronic modulation of glucocorticoid levels commencing early in life evokes additional, adaptive, and compensatory mechanisms that contribute to the regulation of granule cell proliferation...
Involvement of stress-released corticotropin-releasing hormone in the basolateral amygdala in regulating memory consolidationBenno Roozendaal
Center for the Neurobiology of Learning and Memory, Department of Neurobiology and Behavior, University of California, Irvine, CA 92697, USA
Proc Natl Acad Sci U S A 99:13908-13. 2002..These findings indicate that activation of CRH receptors in the BLA, likely by training-induced release of endogenous peptide originating from the CEA, participates in mediating stress effects on memory consolidation...
Mechanisms of late-onset cognitive decline after early-life stressKristen L Brunson
Department of Anatomy/Neurobiology, University of California, Irvine, California 92697-4475, USA
J Neurosci 25:9328-38. 2005....
Corticotropin-releasing hormone (CRH) downregulates the function of its receptor (CRF1) and induces CRF1 expression in hippocampal and cortical regions of the immature rat brainKristen L Brunson
Department of Anatomy and Neurobiology, University of California at Irvine, Irvine, California 92697, USA
Exp Neurol 176:75-86. 2002....
Endogenous neuropeptide Y prevents recurrence of experimental febrile seizures by increasing seizure thresholdCeline Dube
Department of Anatomy and Neurobiology, University of California at Irvine, Irvine, CA 92697, USA
J Mol Neurosci 25:275-84. 2005....
Modulation of dendritic differentiation by corticotropin-releasing factor in the developing hippocampusYuncai Chen
Departments of Anatomy Neurobiology and Pediatrics, University of California, Irvine, CA 92697 4475
Proc Natl Acad Sci U S A 101:15782-7. 2004..Taken together, these findings suggest that endogenous CRF, if released excessively by previous early postnatal stress, might influence neuronal connectivity and thus function of the immature hippocampus...
Stressed-out, or in (utero)?Sarit Avishai-Eliner
Dept of Anatomy and Neurobiology, University of California at Irvine, 92697, USA
Trends Neurosci 25:518-24. 2002..Importantly, these CRH-mediated processes could be targets of preventive and interventional strategies...
Hippocampal neuroplasticity induced by early-life stress: functional and molecular aspectsKristina A Fenoglio
Department of Anatomy/Neurobiology, University of California at Irvine, 92697-4475, USA
Front Neuroendocrinol 27:180-92. 2006..We review the cellular mechanisms involved and discuss the roles of stress-mediating molecules, including corticotropin releasing hormone, in the process by which stress impacts the structure and function of hippocampal neurons...
