Research Topics
| Pablo Rodolfo BrumovskySummaryAffiliation: University of Pittsburgh Country: USA Publications
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Publications
Expression of vesicular glutamate transporters in sensory and autonomic neurons innervating the mouse bladderPablo R Brumovsky
Pittsburgh Center for Pain Research, Department of Anesthesiology, University of Pittsburgh, Pittsburgh, Pennsylvania Consejo Nacional de Investigaciones Científicas y Técnicas and School of Biomedical Sciences, Austral University, Buenos Aires, Argentina Electronic address
J Urol 189:2342-9. 2013..However, to our knowledge the expression of VGLUTs in neurons innervating the bladder has not yet been analyzed. We studied VGLUT1, VGLUT2 and VGLUT3 in mouse bladder neurons...
Expression of vesicular glutamate transporters type 1 and 2 in sensory and autonomic neurons innervating the mouse colorectumPablo R Brumovsky
Pittsburgh Center for Pain Research, Department of Anesthesiology, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
J Comp Neurol 519:3346-66. 2011..Altogether, our data suggests a role for VGLUT(2) in colorectal glutamatergic neurotransmission, potentially influencing colorectal sensitivity and motility...
Some lumbar sympathetic neurons develop a glutamatergic phenotype after peripheral axotomy with a note on VGLUT₂-positive perineuronal basketsPablo R Brumovsky
Pittsburgh Center for Pain Research, Deparment of Anesthesiology, University of Pittsburgh, Pittsburgh, PA 15213, USA
Exp Neurol 230:258-72. 2011..Taken together, axotomy of visceral and non-visceral nerves results in a glutamatergic phenotype of some LSC neurons. In addition, we show previously non-described MPG perineuronal glutamatergic baskets...
Cystitis increases colorectal afferent sensitivity in the mousePablo Rodolfo Brumovsky
Center for Pain Research, Departments of Anesthesiology, University of Pittsburgh, Pennsylvania, USA
Am J Physiol Gastrointest Liver Physiol 297:G1250-8. 2009..These data support a peripheral contribution to cross-organ sensitization of pelvic organs...
Neuropeptide tyrosine and painPablo Brumovsky
Department of Neuroscience, Karolinska Institutet, S 171 77 Stockholm, Sweden
Trends Pharmacol Sci 28:93-102. 2007....
Expression of the vesicular glutamate transporters-1 and -2 in adult mouse dorsal root ganglia and spinal cord and their regulation by nerve injuryP Brumovsky
Department of Neuroscience, Karolinska Institutet, Retzius vag 8, B2 5, S 171 77 Stockholm, Sweden
Neuroscience 147:469-90. 2007..J Comp Neurol 483:1-16], we speculate that virtually all DRG neurons in adult mouse express VGLUTs and use glutamate as transmitter...
Differential galanin upregulation in dorsal root ganglia and spinal cord after graded single ligature nerve constriction of the rat sciatic nerveMaría Florencia Coronel
School of Biomedical Sciences, Austral University, Av Pte Perón 1500, B1629AHJ Pilar, Buenos Aires, Argentina
J Chem Neuroanat 35:94-100. 2008..These results show that galanin expression in DRGs and spinal cord is differentially regulated by different degrees of nerve constriction and further support its modulatory role on neuropathic pain...
Phenotyping of sensory and sympathetic ganglion neurons of a galanin-overexpressing mouse--possible implications for pain processingPablo Brumovsky
Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden
J Chem Neuroanat 31:243-62. 2006..Hao, J.X., Xu, X.J., Hökfelt, T., Crawley, J.N., Wiesenfeld-Hallin, Z., 2004. Galanin over-expression decreases the development of neuropathic pain-like behaviour in mice after partial sciatic nerve injury. Brain Res. 1025, 152-158]...
NPY and pain as seen from the histochemical sideTomas Hokfelt
Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden
Peptides 28:365-72. 2007..Taken together with behavioral and electrophysiological results summarized by Smith et al. in this volume, histochemical analyses have advanced the knowledge on the role of NPY in pain processing...
Neuropeptide Y2 receptor protein is present in peptidergic and nonpeptidergic primary sensory neurons of the mousePablo Brumovsky
Department of Neuroscience, Karolinska Institutet, S 171 77 Stockholm, Sweden
J Comp Neurol 489:328-48. 2005..The results also support a role for this receptor and NPY in pain mechanisms...
Characterization of neuropeptide Y2 receptor protein expression in the mouse brain. I. Distribution in cell bodies and nerve terminalsDavor Stanic
Department of Neuroscience, Karolinska Institutet, S 17177 Stockholm, Sweden
J Comp Neurol 499:357-90. 2006..Localization of the Y2R suggests that it is mostly presynaptic, a view supported by its frequent absence in cell bodies in the normal mouse and its dramatic increase in cell bodies of colchicine-treated mice...
Differential distribution and regulation of galanin receptors- 1 and -2 in the rat lumbar spinal cordPablo Brumovsky
Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden
Brain Res 1085:111-20. 2006..Furthermore, the nerve injury-induced Gal(2) upregulation in motor neurons suggests a role for galanin in survival/regeneration mechanisms...
Tyrosine hydroxylase is expressed in a subpopulation of small dorsal root ganglion neurons in the adult mousePablo Brumovsky
Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden
Exp Neurol 200:153-65. 2006..A further alternative is that L-DOPA after release is extracellularly converted to dopamine...
Galanin over-expression decreases the development of neuropathic pain-like behaviors in mice after partial sciatic nerve injuryKarin Hygge-Blakeman
Department of Laboratory Medicine, Division of Clinical Neurophysiology, Huddinge University Hospital, S 141 86 Huddinge, Sweden
Brain Res 1025:152-8. 2004....
