Pablo Rodolfo Brumovsky

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. doi request reprint Expression of vesicular glutamate transporters in sensory and autonomic neurons innervating the mouse bladder
    Pablo R Brumovsky
    Pittsburgh Center for Pain Research, Department of Anesthesiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    J Urol 189:2342-9. 2013
  2. doi request reprint Expression of vesicular glutamate transporters type 1 and 2 in sensory and autonomic neurons innervating the mouse colorectum
    Pablo R Brumovsky
    Pittsburgh Center for Pain Research, Department of Anesthesiology, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    J Comp Neurol 519:3346-66. 2011
  3. pmc Some lumbar sympathetic neurons develop a glutamatergic phenotype after peripheral axotomy with a note on VGLUT₂-positive perineuronal baskets
    Pablo R Brumovsky
    Pittsburgh Center for Pain Research, Deparment of Anesthesiology, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Exp Neurol 230:258-72. 2011
  4. pmc Cystitis increases colorectal afferent sensitivity in the mouse
    Pablo Rodolfo Brumovsky
    Center for Pain Research, Departments of Anesthesiology, University of Pittsburgh, Pennsylvania, USA
    Am J Physiol Gastrointest Liver Physiol 297:G1250-8. 2009
  5. ncbi request reprint Neuropeptide tyrosine and pain
    Pablo Brumovsky
    Department of Neuroscience, Karolinska Institutet, S 171 77 Stockholm, Sweden
    Trends Pharmacol Sci 28:93-102. 2007
  6. ncbi request reprint Expression of the vesicular glutamate transporters-1 and -2 in adult mouse dorsal root ganglia and spinal cord and their regulation by nerve injury
    P Brumovsky
    Department of Neuroscience, Karolinska Institutet, Retzius vag 8, B2 5, S 171 77 Stockholm, Sweden
    Neuroscience 147:469-90. 2007
  7. ncbi request reprint Differential galanin upregulation in dorsal root ganglia and spinal cord after graded single ligature nerve constriction of the rat sciatic nerve
    María Florencia Coronel
    School of Biomedical Sciences, Austral University, Av Pte Perón 1500, B1629AHJ Pilar, Buenos Aires, Argentina
    J Chem Neuroanat 35:94-100. 2008
  8. ncbi request reprint Phenotyping of sensory and sympathetic ganglion neurons of a galanin-overexpressing mouse--possible implications for pain processing
    Pablo Brumovsky
    Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden
    J Chem Neuroanat 31:243-62. 2006
  9. ncbi request reprint NPY and pain as seen from the histochemical side
    Tomas Hokfelt
    Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden
    Peptides 28:365-72. 2007
  10. ncbi request reprint Neuropeptide Y2 receptor protein is present in peptidergic and nonpeptidergic primary sensory neurons of the mouse
    Pablo Brumovsky
    Department of Neuroscience, Karolinska Institutet, S 171 77 Stockholm, Sweden
    J Comp Neurol 489:328-48. 2005

Detail Information

Publications14

  1. doi request reprint Expression of vesicular glutamate transporters in sensory and autonomic neurons innervating the mouse bladder
    Pablo R Brumovsky
    Pittsburgh Center for Pain Research, Department of Anesthesiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    J Urol 189:2342-9. 2013
    ..However, to our knowledge the expression of VGLUTs in neurons innervating the bladder has not yet been analyzed. We studied VGLUT1, VGLUT2 and VGLUT3 in mouse bladder neurons...
  2. doi request reprint Expression of vesicular glutamate transporters type 1 and 2 in sensory and autonomic neurons innervating the mouse colorectum
    Pablo R Brumovsky
    Pittsburgh Center for Pain Research, Department of Anesthesiology, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    J Comp Neurol 519:3346-66. 2011
    ..Altogether, our data suggests a role for VGLUT(2) in colorectal glutamatergic neurotransmission, potentially influencing colorectal sensitivity and motility...
  3. pmc Some lumbar sympathetic neurons develop a glutamatergic phenotype after peripheral axotomy with a note on VGLUT₂-positive perineuronal baskets
    Pablo R Brumovsky
    Pittsburgh Center for Pain Research, Deparment of Anesthesiology, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Exp Neurol 230:258-72. 2011
    ..Taken together, axotomy of visceral and non-visceral nerves results in a glutamatergic phenotype of some LSC neurons. In addition, we show previously non-described MPG perineuronal glutamatergic baskets...
  4. pmc Cystitis increases colorectal afferent sensitivity in the mouse
    Pablo Rodolfo Brumovsky
    Center for Pain Research, Departments of Anesthesiology, University of Pittsburgh, Pennsylvania, USA
    Am J Physiol Gastrointest Liver Physiol 297:G1250-8. 2009
    ..These data support a peripheral contribution to cross-organ sensitization of pelvic organs...
  5. ncbi request reprint Neuropeptide tyrosine and pain
    Pablo Brumovsky
    Department of Neuroscience, Karolinska Institutet, S 171 77 Stockholm, Sweden
    Trends Pharmacol Sci 28:93-102. 2007
    ....
  6. ncbi request reprint Expression of the vesicular glutamate transporters-1 and -2 in adult mouse dorsal root ganglia and spinal cord and their regulation by nerve injury
    P Brumovsky
    Department of Neuroscience, Karolinska Institutet, Retzius vag 8, B2 5, S 171 77 Stockholm, Sweden
    Neuroscience 147:469-90. 2007
    ..J Comp Neurol 483:1-16], we speculate that virtually all DRG neurons in adult mouse express VGLUTs and use glutamate as transmitter...
  7. ncbi request reprint Differential galanin upregulation in dorsal root ganglia and spinal cord after graded single ligature nerve constriction of the rat sciatic nerve
    María Florencia Coronel
    School of Biomedical Sciences, Austral University, Av Pte Perón 1500, B1629AHJ Pilar, Buenos Aires, Argentina
    J Chem Neuroanat 35:94-100. 2008
    ..These results show that galanin expression in DRGs and spinal cord is differentially regulated by different degrees of nerve constriction and further support its modulatory role on neuropathic pain...
  8. ncbi request reprint Phenotyping of sensory and sympathetic ganglion neurons of a galanin-overexpressing mouse--possible implications for pain processing
    Pablo Brumovsky
    Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden
    J Chem Neuroanat 31:243-62. 2006
    ..Hao, J.X., Xu, X.J., Hökfelt, T., Crawley, J.N., Wiesenfeld-Hallin, Z., 2004. Galanin over-expression decreases the development of neuropathic pain-like behaviour in mice after partial sciatic nerve injury. Brain Res. 1025, 152-158]...
  9. ncbi request reprint NPY and pain as seen from the histochemical side
    Tomas Hokfelt
    Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden
    Peptides 28:365-72. 2007
    ..Taken together with behavioral and electrophysiological results summarized by Smith et al. in this volume, histochemical analyses have advanced the knowledge on the role of NPY in pain processing...
  10. ncbi request reprint Neuropeptide Y2 receptor protein is present in peptidergic and nonpeptidergic primary sensory neurons of the mouse
    Pablo Brumovsky
    Department of Neuroscience, Karolinska Institutet, S 171 77 Stockholm, Sweden
    J Comp Neurol 489:328-48. 2005
    ..The results also support a role for this receptor and NPY in pain mechanisms...
  11. ncbi request reprint Characterization of neuropeptide Y2 receptor protein expression in the mouse brain. I. Distribution in cell bodies and nerve terminals
    Davor Stanic
    Department of Neuroscience, Karolinska Institutet, S 17177 Stockholm, Sweden
    J Comp Neurol 499:357-90. 2006
    ..Localization of the Y2R suggests that it is mostly presynaptic, a view supported by its frequent absence in cell bodies in the normal mouse and its dramatic increase in cell bodies of colchicine-treated mice...
  12. ncbi request reprint Differential distribution and regulation of galanin receptors- 1 and -2 in the rat lumbar spinal cord
    Pablo Brumovsky
    Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden
    Brain Res 1085:111-20. 2006
    ..Furthermore, the nerve injury-induced Gal(2) upregulation in motor neurons suggests a role for galanin in survival/regeneration mechanisms...
  13. ncbi request reprint Tyrosine hydroxylase is expressed in a subpopulation of small dorsal root ganglion neurons in the adult mouse
    Pablo Brumovsky
    Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden
    Exp Neurol 200:153-65. 2006
    ..A further alternative is that L-DOPA after release is extracellularly converted to dopamine...
  14. ncbi request reprint Galanin over-expression decreases the development of neuropathic pain-like behaviors in mice after partial sciatic nerve injury
    Karin Hygge-Blakeman
    Department of Laboratory Medicine, Division of Clinical Neurophysiology, Huddinge University Hospital, S 141 86 Huddinge, Sweden
    Brain Res 1025:152-8. 2004
    ....