Eugene N Bruce

Summary

Affiliation: University of Kentucky
Country: USA

Publications

  1. ncbi request reprint A multicompartment model of carboxyhemoglobin and carboxymyoglobin responses to inhalation of carbon monoxide
    Eugene N Bruce
    Center for Biomedical Engineering, University of Kentucky, Lexington, KY 40506 0070, USA
    J Appl Physiol 95:1235-47. 2003
  2. pmc A mathematical modeling approach to risk assessment for normal and anemic women chronically exposed to carbon monoxide from biomass-fueled cookstoves
    Eugene N Bruce
    Center for Biomedical Engineering, University of Kentucky, Lexington, KY 40506 0070, USA
    J Appl Physiol 111:473-84. 2011
  3. pmc Prediction of the rate of uptake of carbon monoxide from blood by extravascular tissues
    Eugene N Bruce
    Center for Biomedical Engineering, University of Kentucky, Lexington, KY 40506 0070, USA
    Respir Physiol Neurobiol 161:142-59. 2008
  4. pmc Sample entropy tracks changes in electroencephalogram power spectrum with sleep state and aging
    Eugene N Bruce
    Center for Biomedical Engineering, University of Kentucky, Lexington, Kentucky 40506 0070, USA
    J Clin Neurophysiol 26:257-66. 2009
  5. pmc Progressive changes in cortical state before and after spontaneous arousals from sleep in elderly and middle-aged women
    E N Bruce
    Center for Biomedical Engineering, University of Kentucky, Lexington, KY, USA
    Neuroscience 175:184-97. 2011
  6. pmc Mutual information analysis of EEG signals indicates age-related changes in cortical interdependence during sleep in middle-aged versus elderly women
    Pravitha Ramanand
    Center for Biomedical Engineering, University of Kentucky, Lexington, Kentucky 40506 0070, USA
    J Clin Neurophysiol 27:274-84. 2010
  7. pmc Transient decoupling of cortical EEGs following arousals during NREM sleep in middle-aged and elderly women
    Pravitha Ramanand
    Center for Biomedical Engineering, University of Kentucky, Lexington, KY 40506 0070, USA
    Int J Psychophysiol 77:71-82. 2010
  8. doi request reprint Computational analyses of CO-rebreathing methods for estimating haemoglobin mass in humans
    Kinnera E Chada
    Center for Biomedical Engineering, University of Kentucky, Lexington, KY 40506 0070, USA
    Exp Physiol 97:141-54. 2012
  9. doi request reprint Prediction of extravascular burden of carbon monoxide (CO) in the human heart
    Kinnera Erupaka
    Center for Biomedical Engineering, University of Kentucky, Lexington, KY 40506 0070, USA
    Ann Biomed Eng 38:403-38. 2010
  10. ncbi request reprint Analysis of factors that influence rates of carbon monoxide uptake, distribution, and washout from blood and extravascular tissues using a multicompartment model
    Margaret C Bruce
    Department of Physiology, University of Kentucky, Lexington, 40506 0070, USA
    J Appl Physiol 100:1171-80. 2006

Collaborators

Detail Information

Publications11

  1. ncbi request reprint A multicompartment model of carboxyhemoglobin and carboxymyoglobin responses to inhalation of carbon monoxide
    Eugene N Bruce
    Center for Biomedical Engineering, University of Kentucky, Lexington, KY 40506 0070, USA
    J Appl Physiol 95:1235-47. 2003
    ..In contrast to approaches based on the Coburn-Forster-Kane equation, the present model predicts uptake and distribution of CO in both vascular and tissue compartments during inhalation of either constant or variable levels of CO...
  2. pmc A mathematical modeling approach to risk assessment for normal and anemic women chronically exposed to carbon monoxide from biomass-fueled cookstoves
    Eugene N Bruce
    Center for Biomedical Engineering, University of Kentucky, Lexington, KY 40506 0070, USA
    J Appl Physiol 111:473-84. 2011
    ..Our results demonstrate the efficacy of using a mathematical model to predict the physiologic responses to CO and also demonstrate that chronic anemia is a critically important determinant of CO toxicity in these women...
  3. pmc Prediction of the rate of uptake of carbon monoxide from blood by extravascular tissues
    Eugene N Bruce
    Center for Biomedical Engineering, University of Kentucky, Lexington, KY 40506 0070, USA
    Respir Physiol Neurobiol 161:142-59. 2008
    ..We conclude that slow uptake is most consistent with all of the experimental data. Slow uptake of CO by tissue is primarily due to the very small blood-to-tissue partial pressure gradients for CO...
  4. pmc Sample entropy tracks changes in electroencephalogram power spectrum with sleep state and aging
    Eugene N Bruce
    Center for Biomedical Engineering, University of Kentucky, Lexington, Kentucky 40506 0070, USA
    J Clin Neurophysiol 26:257-66. 2009
    ..029) and rapid eye movement (P = 0.001), suggesting that cortical state is shifted toward alertness in elderly subjects in these sleep states compared with the middle-aged subjects...
  5. pmc Progressive changes in cortical state before and after spontaneous arousals from sleep in elderly and middle-aged women
    E N Bruce
    Center for Biomedical Engineering, University of Kentucky, Lexington, KY, USA
    Neuroscience 175:184-97. 2011
    ....
  6. pmc Mutual information analysis of EEG signals indicates age-related changes in cortical interdependence during sleep in middle-aged versus elderly women
    Pravitha Ramanand
    Center for Biomedical Engineering, University of Kentucky, Lexington, Kentucky 40506 0070, USA
    J Clin Neurophysiol 27:274-84. 2010
    ..The loss of synchronization between neural activities during sleep in the elderly may make these women more susceptible to localized disturbances that could lead to frequent arousals...
  7. pmc Transient decoupling of cortical EEGs following arousals during NREM sleep in middle-aged and elderly women
    Pravitha Ramanand
    Center for Biomedical Engineering, University of Kentucky, Lexington, KY 40506 0070, USA
    Int J Psychophysiol 77:71-82. 2010
    ..The findings suggest that the state following an arousal characterized by lower interdependence may resemble a more vigilant period during which the system may be vulnerable to more arousals...
  8. doi request reprint Computational analyses of CO-rebreathing methods for estimating haemoglobin mass in humans
    Kinnera E Chada
    Center for Biomedical Engineering, University of Kentucky, Lexington, KY 40506 0070, USA
    Exp Physiol 97:141-54. 2012
    ..Regression equations were developed to improve the estimation of volume of CO bound to myoglobin, and a new protocol that is less dependent on the site of blood sampling is proposed...
  9. doi request reprint Prediction of extravascular burden of carbon monoxide (CO) in the human heart
    Kinnera Erupaka
    Center for Biomedical Engineering, University of Kentucky, Lexington, KY 40506 0070, USA
    Ann Biomed Eng 38:403-38. 2010
    ..Because the model can predict CO uptake and distribution in human myocardium, it could be a tool to estimate the potential for hypoxic myocardial injury and facilitate therapeutic intervention...
  10. ncbi request reprint Analysis of factors that influence rates of carbon monoxide uptake, distribution, and washout from blood and extravascular tissues using a multicompartment model
    Margaret C Bruce
    Department of Physiology, University of Kentucky, Lexington, 40506 0070, USA
    J Appl Physiol 100:1171-80. 2006
    ..Thus exposure conditions, COHb sampling times, and individual parameters should be considered when estimating CO washout rates for poisoning victims...
  11. ncbi request reprint Dexamethasone-induced changes in lung function are not prevented by concomitant treatment with retinoic acid
    Ganesh Srinivasan
    Department of Pediatrics, University of Kentucky Medical School, Lexington, Kentucky 40536, USA
    Am J Physiol Lung Cell Mol Physiol 283:L275-87. 2002
    ..006). Despite impaired septation, O(2) saturation was not compromised in Dex- or Dex + RA-treated rats. Thus lung function changes induced by Dex treatment during alveolarization were not prevented by concomitant treatment with RA...