John O Brooks

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Neurocognitive costs and benefits of psychotropic medications in older adults
    John O Brooks
    Palo Alto Veterans Affairs Health Care System and Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California, USA
    J Geriatr Psychiatry Neurol 20:199-214. 2007
  2. pmc Corticolimbic metabolic dysregulation in euthymic older adults with bipolar disorder
    John O Brooks
    UCLA Semel Institute, Los Angeles, CA 90025, USA
    J Psychiatr Res 43:497-502. 2009
  3. doi request reprint Substance use disorders as risk factors for psychiatric hospitalization in bipolar disorder
    Jennifer C Hoblyn
    Palo Alto Veterans Affairs Health Care System, Palo Alto, California, USA
    Psychiatr Serv 60:50-5. 2009
  4. ncbi request reprint Metabolic risks in older adults receiving second-generation antipsychotic medication
    John O Brooks
    UCLA Semel Institute, MC 175919, 760 Westwood Plaza, B8 233B NPI, Los Angeles, CA 90024, USA
    Curr Psychiatry Rep 11:33-40. 2009
  5. doi request reprint Metabolic evidence of corticolimbic dysregulation in bipolar mania
    John O Brooks
    UCLA Semel Institute, 760 Westwood Plaza, B3 233 NPI, Los Angeles, CA 90024 1759, USA
    Psychiatry Res 181:136-40. 2010
  6. doi request reprint Resting prefrontal hypometabolism and paralimbic hypermetabolism related to verbal recall deficits in euthymic older adults with bipolar disorder
    John O Brooks
    UCLA Semel Institute and Department of Psychiatry, Los Angeles, CA 90024 1759, USA
    Am J Geriatr Psychiatry 17:1022-9. 2009
  7. doi request reprint Preliminary evidence of within-subject changes in gray matter density associated with remission of bipolar depression
    John O Brooks
    Semel Institute for Neuroscience and Human Behavior at UCLA, Los Angeles, CA 90024, USA
    Psychiatry Res 193:53-5. 2011
  8. doi request reprint Safety and tolerability associated with second-generation antipsychotic polytherapy in bipolar disorder: findings from the Systematic Treatment Enhancement Program for Bipolar Disorder
    John O Brooks
    UCLA Semel Institute, Los Angeles, California, USA
    J Clin Psychiatry 72:240-7. 2011
  9. doi request reprint Prefrontal and paralimbic metabolic dysregulation related to sustained attention in euthymic older adults with bipolar disorder
    John O Brooks
    Semel Institute for Neuroscience and Human Behavior, 760 Westwood Plaza, Los Angeles, CA 90024, USA
    Bipolar Disord 12:866-74. 2010
  10. pmc Mood-state effects on amygdala volume in bipolar disorder
    Lara C Foland-Ross
    Laboratory of Neuro Imaging, Dept of Neurology, UCLA School of Medicine, Los Angeles, CA, USA
    J Affect Disord 139:298-301. 2012

Collaborators

Detail Information

Publications11

  1. ncbi request reprint Neurocognitive costs and benefits of psychotropic medications in older adults
    John O Brooks
    Palo Alto Veterans Affairs Health Care System and Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California, USA
    J Geriatr Psychiatry Neurol 20:199-214. 2007
    ..The neurocognitive costs and benefits of psychiatric medications should be considered in the context of disease treatment in older adults...
  2. pmc Corticolimbic metabolic dysregulation in euthymic older adults with bipolar disorder
    John O Brooks
    UCLA Semel Institute, Los Angeles, CA 90025, USA
    J Psychiatr Res 43:497-502. 2009
    ..Persistent corticolimbic dysregulation may be related to residual affective, behavioral, and cognitive symptoms in older patients with bipolar disorder, even when not experiencing syndromal mood disturbance...
  3. doi request reprint Substance use disorders as risk factors for psychiatric hospitalization in bipolar disorder
    Jennifer C Hoblyn
    Palo Alto Veterans Affairs Health Care System, Palo Alto, California, USA
    Psychiatr Serv 60:50-5. 2009
    ..This study developed risk profiles of psychiatric hospitalization for veterans diagnosed as having bipolar disorder...
  4. ncbi request reprint Metabolic risks in older adults receiving second-generation antipsychotic medication
    John O Brooks
    UCLA Semel Institute, MC 175919, 760 Westwood Plaza, B8 233B NPI, Los Angeles, CA 90024, USA
    Curr Psychiatry Rep 11:33-40. 2009
    ..Although lifestyle modifications can help to reduce some aspects of metabolic syndrome, lifestyle modifications in conjunction with metformin therapy appear to be most effective...
  5. doi request reprint Metabolic evidence of corticolimbic dysregulation in bipolar mania
    John O Brooks
    UCLA Semel Institute, 760 Westwood Plaza, B3 233 NPI, Los Angeles, CA 90024 1759, USA
    Psychiatry Res 181:136-40. 2010
    ..The findings support the hypothesis of corticolimbic dysregulation as a crucial contributor to the pathophysiology of bipolar disorder...
  6. doi request reprint Resting prefrontal hypometabolism and paralimbic hypermetabolism related to verbal recall deficits in euthymic older adults with bipolar disorder
    John O Brooks
    UCLA Semel Institute and Department of Psychiatry, Los Angeles, CA 90024 1759, USA
    Am J Geriatr Psychiatry 17:1022-9. 2009
    ..To evaluate deficits of delayed free recall in euthymic older patients with bipolar disorder and relate deficits to resting cerebral metabolism...
  7. doi request reprint Preliminary evidence of within-subject changes in gray matter density associated with remission of bipolar depression
    John O Brooks
    Semel Institute for Neuroscience and Human Behavior at UCLA, Los Angeles, CA 90024, USA
    Psychiatry Res 193:53-5. 2011
    ..Decreases were observed in superior and inferior frontal gyri and anterior cingulate...
  8. doi request reprint Safety and tolerability associated with second-generation antipsychotic polytherapy in bipolar disorder: findings from the Systematic Treatment Enhancement Program for Bipolar Disorder
    John O Brooks
    UCLA Semel Institute, Los Angeles, California, USA
    J Clin Psychiatry 72:240-7. 2011
    ..Practitioners often combine 2 or more second-generation antipsychotics (SGAs) in patients with bipolar disorder, despite an absence of data to support their safety, tolerability, or efficacy...
  9. doi request reprint Prefrontal and paralimbic metabolic dysregulation related to sustained attention in euthymic older adults with bipolar disorder
    John O Brooks
    Semel Institute for Neuroscience and Human Behavior, 760 Westwood Plaza, Los Angeles, CA 90024, USA
    Bipolar Disord 12:866-74. 2010
    ..In the present study, we evaluated relationships between cognitive performance deficits and resting cerebral metabolism in euthymic older adults with bipolar disorder...
  10. pmc Mood-state effects on amygdala volume in bipolar disorder
    Lara C Foland-Ross
    Laboratory of Neuro Imaging, Dept of Neurology, UCLA School of Medicine, Los Angeles, CA, USA
    J Affect Disord 139:298-301. 2012
    ..The prefrontal cortex has recently been reported to have a lower volume in depressed versus euthymic bipolar patients. Here we examined whether similar mood state-dependent volumetric differences are detectable in the amygdala...
  11. doi request reprint Predictive socioeconomic and clinical profiles of antidepressant response and remission
    Felipe A Jain
    Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, California 90024, USA
    Depress Anxiety 30:624-30. 2013
    ..The predictive power of any single factor, however, is limited. We aimed to develop profiles of antidepressant response and remission based upon hierarchical combinations of baseline clinical and demographic factors...